phenobarbital has been researched along with Graves Disease in 5 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "With the diagnosis of neonatal Graves' disease established, both twins were treated with propranolol (2 mg/kg." | 1.30 | [Neonatal Basedow's disease in twins from a mother with severe T3 hyperthyroidism]. ( Grüters, A; Hüfner, M; Lakomek, M; Roth, C; Siggelkow, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| POPEK, K | 1 |
| Roth, C | 1 |
| Siggelkow, H | 1 |
| Grüters, A | 1 |
| Hüfner, M | 1 |
| Lakomek, M | 1 |
| Oppenheimer, JH | 1 |
| Orbeck, H | 1 |
| Cavlieri, RR | 1 |
| Sung, LC | 1 |
| Becker, CE | 1 |
1 review available for phenobarbital and Graves Disease
| Article | Year |
|---|---|
Interaction of drugs with thyroid hormone binding sites.
Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Diseas | 1973 |
4 other studies available for phenobarbital and Graves Disease
| Article | Year |
|---|---|
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromid | 1964 |
[Neonatal Basedow's disease in twins from a mother with severe T3 hyperthyroidism].
Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Autoantibodies; Developmental Disabilities; | 1997 |
Neonatal hyperthyroidism.
Topics: Adult; Body Weight; Breast Diseases; Diarrhea; Digitalis Glycosides; Female; Graves Disease; Humans; | 1973 |
Effects of phenobarbital on thyroxine and triiodothyronine kinetics in Graves' disease.
Topics: Feces; Female; Graves Disease; Humans; Iodine Isotopes; Kinetics; Liver; Male; Phenobarbital; Radioi | 1973 |