phenobarbital has been researched along with Fetal Growth Retardation in 10 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Fetal Growth Retardation: Failure of a FETUS to attain expected GROWTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While cocaine is now used much more frequently than heroin by women of childbearing age, we have found that a significant number of mothers have abused both drugs during their pregnancy." | 3.67 | Perinatal outcome of infants exposed to cocaine and/or heroin in utero. ( Durand, DJ; Fulroth, R; Phillips, B, 1989) |
| "The aim of the study was to compare the effect of phenobarbital given to pregnant rabbits and of epileptic seizures on the course of pregnancy, the physical state, and central nervous system development of newborns." | 3.66 | [Comparison of the transplacental effect of luminal and epileptic seizures in pregnant rabbits on the development of the fetal nervous system]. ( Bryłko-Chmielik, J; Dambska, M; Danielewicz-Kotowicz, A; Dydyk, L; Maślińska, D; Onyszkiewicz, J, 1979) |
| "The risks of preeclampsia (adjusted odds ratio [OR] 1." | 1.35 | Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. ( Fraser, W; Olatunbosun, O; Walker, M; Wen, SW; Yang, Q; Zhou, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, SW | 1 |
| Zhou, J | 1 |
| Yang, Q | 1 |
| Fraser, W | 1 |
| Olatunbosun, O | 1 |
| Walker, M | 1 |
| Ramsey, PS | 1 |
| Rouse, DJ | 1 |
| Holmes, LB | 1 |
| Harvey, EA | 1 |
| Coull, BA | 1 |
| Huntington, KB | 1 |
| Khoshbin, S | 1 |
| Hayes, AM | 1 |
| Ryan, LM | 1 |
| Dambska, M | 1 |
| Bryłko-Chmielik, J | 1 |
| Danielewicz-Kotowicz, A | 1 |
| Dydyk, L | 1 |
| Maślińska, D | 1 |
| Onyszkiewicz, J | 1 |
| Redmond, GP | 1 |
| Kattner, E | 1 |
| Fulroth, R | 1 |
| Phillips, B | 1 |
| Durand, DJ | 1 |
| Finnell, RH | 1 |
| Shields, HE | 1 |
| Chernoff, GF | 1 |
| Bertollini, R | 1 |
| Källen, B | 1 |
| Mastroiacovo, P | 1 |
| Robert, E | 1 |
| Matsuoka, R | 1 |
| Gilbert, EF | 1 |
| Bruyers, H | 1 |
| Optiz, JM | 1 |
3 reviews available for phenobarbital and Fetal Growth Retardation
| Article | Year |
|---|---|
Therapies administered to mothers at risk for preterm birth and neurodevelopmental outcome in their infants.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Developmental Disabilities; Excitatory Amino Acid A | 2002 |
Effect of drugs on intrauterine growth.
Topics: Abnormalities, Drug-Induced; Animals; Ethanol; Female; Fetal Growth Retardation; Fetus; Growth; Huma | 1979 |
[Findings in newborn infants following drug abuse or drug weaning in the mother].
Topics: Abnormalities, Drug-Induced; Adult; Female; Fetal Growth Retardation; Heroin Dependence; Humans; Inf | 1991 |
7 other studies available for phenobarbital and Fetal Growth Retardation
| Article | Year |
|---|---|
Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes.
Topics: Abruptio Placentae; Adult; Cohort Studies; Female; Fetal Death; Fetal Growth Retardation; Folic Acid | 2008 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnorm | 2001 |
[Comparison of the transplacental effect of luminal and epileptic seizures in pregnant rabbits on the development of the fetal nervous system].
Topics: Anencephaly; Animals; Brain Stem; Cerebral Cortex; Epilepsy, Tonic-Clonic; Female; Fetal Growth Reta | 1979 |
Perinatal outcome of infants exposed to cocaine and/or heroin in utero.
Topics: Cocaine; Drug Synergism; Female; Fetal Growth Retardation; Heroin; Humans; Infant, Newborn; Microcep | 1989 |
Variable patterns in anticonvulsant drug-induced malformations in mice: comparisons of phenytoin and phenobarbital.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Growth Retardation; Mice; Mice, Inbred Strains; | 1987 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fe | 1987 |
An aborted human fetus with truncus arteriosus communis--possible teratogenic effect of Tedral.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Drug Combinations; Embryo, Mammalian; Eph | 1985 |