phenobarbital has been researched along with Fetal Death in 24 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The risks of preeclampsia (adjusted odds ratio [OR] 1." | 1.35 | Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. ( Fraser, W; Olatunbosun, O; Walker, M; Wen, SW; Yang, Q; Zhou, J, 2008) |
| "Phenobarbital was found to have a significant teratogenic potential in mice, resulting in skeletal, cardiac, renal, neural, and urogenital defects in a dose-related fashion." | 1.27 | Strain differences in phenobarbital-induced teratogenesis in mice. ( Chernoff, GF; Finnell, RH; Shields, HE; Taylor, SM, 1987) |
| "Pregnancies complicated by severe preeclampsia in the second trimester are associated with a high incidence of perinatal morbidity and mortality." | 1.27 | Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester. ( Abdella, TN; Anderson, GD; Brooks, TF; Sibai, BM; Spinnato, JA; Taslimi, M, 1985) |
| "Phenobarbital treatment antagonized THC-induced reduction of fetal body weight, but did not reduce resorption rate." | 1.26 | Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism. ( Harbison, RD; Lubin, DJ; Mantilla-Plata, B, 1977) |
| "A daily dosage of 100 mg phenobarbitone administered orally to pregnant women for three days or more immediately before delivery has reduced the various mortality rates for low-birth-weight infants by 50% or more." | 1.26 | Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment. ( Trolle, D, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (95.83) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, SW | 1 |
| Zhou, J | 1 |
| Yang, Q | 1 |
| Fraser, W | 1 |
| Olatunbosun, O | 1 |
| Walker, M | 1 |
| HANS, SF | 1 |
| KOPELMAN, H | 1 |
| WINBERG, J | 1 |
| OLIVECRONA, H | 1 |
| Hiilesmaa, VK | 1 |
| Teramo, K | 1 |
| Granström, ML | 1 |
| Bardy, AH | 1 |
| Nomura, T | 1 |
| Isa, Y | 1 |
| Kurokawa, N | 1 |
| Kanzaki, T | 1 |
| Tanaka, H | 1 |
| Tada, E | 1 |
| Sakamoto, Y | 1 |
| Walker, W | 1 |
| Harbison, RD | 2 |
| Mantilla-Plata, B | 1 |
| Lubin, DJ | 1 |
| Biale, Y | 1 |
| Lewenthal, H | 1 |
| Aderet, NB | 1 |
| Trolle, D | 1 |
| Ching, M | 1 |
| Tang, L | 1 |
| Finnell, RH | 1 |
| Shields, HE | 1 |
| Taylor, SM | 1 |
| Chernoff, GF | 1 |
| Stumpf, DA | 1 |
| Sibai, BM | 1 |
| Taslimi, M | 1 |
| Abdella, TN | 1 |
| Brooks, TF | 1 |
| Spinnato, JA | 1 |
| Anderson, GD | 1 |
| Waddell, WJ | 1 |
| Wynnne, WP | 1 |
| Milkovich, L | 1 |
| van den Berg, BJ | 1 |
| Waltman, R | 1 |
| Tricomi, V | 1 |
| Shabanah, EH | 1 |
| Arenas, R | 1 |
| Fedrick, J | 1 |
| Halbrecht, I | 1 |
| Komlos, L | 1 |
| Shabtay, F | 1 |
| Solomon, M | 1 |
| Böök, JA | 1 |
| Wilson, JT | 1 |
| Behrman, RE | 1 |
| Fisher, D | 1 |
| Paton, JB | 1 |
| Keller, J | 1 |
| Fox, LP | 1 |
| Grandi, J | 1 |
| Johnson, AH | 1 |
| Watrous, WG | 1 |
| Johnson, MJ | 1 |
| Sinclair, JG | 1 |
| Abreu, BE | 1 |
3 reviews available for phenobarbital and Fetal Death
| Article | Year |
|---|---|
Haemolytic anaemia in the newborn infant.
Topics: ABO Blood-Group System; Amniocentesis; Antibodies; Blood Group Incompatibility; Blood Transfusion, I | 1975 |
Phenobarbital in the perinatal period.
Topics: Animals; Animals, Newborn; Bilirubin; Chemical and Drug Induced Liver Injury; Drug Antagonism; Drug | 1969 |
In utero disease and the newborn infant.
Topics: Acid-Base Equilibrium; Acidosis; Amniotic Fluid; Animals; Bilirubin; Birth Weight; Electrocardiograp | 1970 |
21 other studies available for phenobarbital and Fetal Death
| Article | Year |
|---|---|
Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes.
Topics: Abruptio Placentae; Adult; Cohort Studies; Female; Fetal Death; Fetal Growth Retardation; Folic Acid | 2008 |
METHYLDOPA IN TREATMENT OF SEVERE TOXAEMIA OF PREGNANCY.
Topics: Albuminuria; Antihypertensive Agents; Chlorothiazide; Female; Fetal Death; Humans; Methyldopa; Pheno | 1964 |
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Ca | 1964 |
EMBRYO-DESTROYING EFFECT OF INJECTED PHENOBARBITAL IN THE MOUSE.
Topics: Animals; Female; Fetal Death; Humans; Mice; Pharmacology; Phenobarbital; Pregnancy; Pregnancy, Anima | 1964 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobar | 1983 |
Enhancement effects of barbital on the teratogenicity of aminopyrine.
Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Barbital; Barbiturates; Cleft Palate; Dose-Respon | 1984 |
Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism.
Topics: Amniotic Fluid; Animals; Body Weight; Cleft Palate; Dronabinol; Drug Interactions; Female; Fetal Dea | 1977 |
Parathion-induced toxicity and phenobarbital-induced protection against parathion during prenatal development.
Topics: Animals; Body Weight; Cholinesterases; Female; Fetal Death; Fetus; Maternal-Fetal Exchange; Mice; Pa | 1975 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord | 1975 |
Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment.
Topics: Birth Weight; Female; Fetal Death; Humans; Infant Mortality; Infant, Newborn; Infant, Premature; Phe | 1976 |
Neuroleptic drug-induced alterations on neonatal growth and development. I. Prenatal exposure influences birth size, mortality rate, and the neuroendocrine system.
Topics: Animals; Animals, Newborn; Birth Weight; Codeine; Dextroamphetamine; Embryonic and Fetal Development | 1986 |
Strain differences in phenobarbital-induced teratogenesis in mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Dose-Response Relationship, Drug; Embryo | 1987 |
Anticonvulsant use during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetal Death; Humans; Phenobarbital; | 1985 |
Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester.
Topics: Administration, Oral; Antihypertensive Agents; Bed Rest; Birth Weight; Delivery, Obstetric; Diuretic | 1985 |
The effect of pretreatment with phenobarbital on the teratogenic action of chorcyclizine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Dealkylation; Drug Antagonism; Embryo Implantati | 1971 |
Effects of prenatal meprobamate and chlordiazepoxide hydrochloride on human embryonic and fetal development.
Topics: Abnormalities, Drug-Induced; Aluminum; Anxiety; Child, Preschool; Chlordiazepoxide; Embryo, Mammalia | 1974 |
The effect of anti-inflammatory drugs on parturition parameters in the rat.
Topics: Acetates; Animals; Aspirin; Cortisone; Depression, Chemical; Female; Fetal Death; Gestational Age; L | 1973 |
Epilepsy and pregnancy: a report from the Oxford Record Linkage Study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Child; Congenital Abnormalities; Drug S | 1973 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |
Pheochromocytoma associated with pregnancy. Specialty team management and review.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, Intravenous; Female; Fetal Death; Humans; Hypertension; | 1969 |
Transplacental effects of drugs in mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Male; Maternal-Fetal Exchange; Methylcell | 1965 |