Page last updated: 2024-11-02

phenobarbital and Fatigue

phenobarbital has been researched along with Fatigue in 10 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Valproic acid has become a regular component of antiepileptic therapy."6.36[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)]. ( Fröscher, W; Gugler, R; Schulz, HU, 1978)
"Valproic acid has become a regular component of antiepileptic therapy."2.36[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)]. ( Fröscher, W; Gugler, R; Schulz, HU, 1978)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NORRIS, AS1
Chelimsky, G1
Chelimsky, T1
Fröscher, W1
Schulz, HU1
Gugler, R1
Aarli, JA1
Snaith, RP1
McCoubrie, M1
Birket-Smith, E1
Lund, M1
Mikkelsen, B1
Vestermark, S1
Olsen, PZ1
Holm, P1
Russell Taylor, WJ1
Frommel, E1
Seydoux, J1
von Ledebur, I1
Chmouliovsky, M1
Prasad, CR1
Richards, RN1
Barnett, HJ1
Wojnarowska, W1

Reviews

1 review available for phenobarbital and Fatigue

ArticleYear
[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1978, Volume: 46, Issue:6

    Topics: Blood Platelets; Drug Interactions; Electroencephalography; Epilepsy; Fatigue; Half-Life; Humans; Ph

1978

Trials

2 trials available for phenobarbital and Fatigue

ArticleYear
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1973, Volume: 53

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinica

1973
A comparative determination of side effects associated with the oral use of three anticholinergic-psychotropic drugs.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:1

    Topics: Adult; Chlordiazepoxide; Clinical Trials as Topic; Constipation; Fatigue; Female; Gastrointestinal D

1970

Other Studies

7 other studies available for phenobarbital and Fatigue

ArticleYear
THE TIRED MOTHER.
    Journal of the Iowa Medical Society, 1964, Volume: 54

    Topics: Antidepressive Agents; Counseling; Depression; Depressive Disorder; Diagnosis; Fatigue; Humans; Marr

1964
Familial association of autonomic and gastrointestinal symptoms.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2001, Volume: 11, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Autonomic Nervous System Diseases; Child; Fatigue; Fem

2001
Effect of clonazepam (Ro 5-4023) on epileptic seizures.
    Acta neurologica Scandinavica. Supplementum, 1973, Volume: 53

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Chlorobenzenes; Drug Evaluatio

1973
Antihypertensive drugs and depression.
    Psychological medicine, 1974, Volume: 4, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Bethanidine; Chlorthalidone; Depression; Diuretics; Drug Thera

1974
Neuropharmacological study of central reactions to intense muscular exertion, sensorial fatigue, sexual excitation, hunger, and thirst.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14

    Topics: Amphetamine; Animals; Brain; Electric Stimulation; Electroshock; Fatigue; Female; Guinea Pigs; Hunge

1966
Paroxysmal dystonic choreoathetosis. A family study and review of the literature.
    Neurology, 1968, Volume: 18, Issue:5

    Topics: Adult; Aged; Amobarbital; Athetosis; Atropine; Benzoates; Caffeine; Child, Preschool; Chorea; Coffee

1968
Influence exerted on auditory fatigue by some calmatives and stimulants of the central nervous system.
    Acta oto-laryngologica, 1966, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Audiometry; Caffeine; Fatigue; Female; Hearing; Humans; Lobeline; Male; Meprobama

1966