phenobarbital has been researched along with Fascioliasis in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maffei Facino, R | 1 |
| Carini, M | 1 |
| Montero, R | 1 |
| Gentile, GJ | 1 |
| Frederick, L | 1 |
| McMannis, J | 1 |
| Murphy, T | 1 |
| Silva, G | 1 |
| Blankespoor, H | 1 |
| Gentile, JM | 1 |
| Galtier, P | 1 |
| Eeckhoutte, C | 1 |
| Larrieu, G | 1 |
| Fowler, JS | 1 |
4 other studies available for phenobarbital and Fascioliasis
| Article | Year |
|---|---|
Loss of substrate binding capacity of the hepatic microsomal cytochrome P-450 in Fasciola hepatica infected rats: toxicological implications.
Topics: Alcohol Oxidoreductases; Animals; Cytochrome P-450 Enzyme System; Fasciola hepatica; Fascioliasis; H | 1982 |
Induced expression of CYP2A5 in inflamed trematode-infested mouse liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cyt | 1999 |
Fasciola hepatica: liver enzymes in rats and interaction with chemical inducers.
Topics: Animals; Arylamine N-Acetyltransferase; Biotransformation; Calcium; Cytochrome P-450 Enzyme System; | 1987 |
Toxicity of carbon tetrachloride and other fasciocidal drugs in sheep and chickens.
Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Anthelmintics; Aspartate Aminotransferases; | 1971 |