phenobarbital has been researched along with Experimental Radiation Injuries in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentobarbital has recently been shown to be a cerebral radioprotectant in the rodent and primate models of single fraction radiation injury." | 1.28 | The cerebral radioprotective effect of alternative barbiturates to pentobarbital. ( DeLaney, T; Oldfield, EH; Olson, JJ; Orr, K; Shelley, C, 1992) |
| "Phenobarbital treatment (60 mg/kg b." | 1.28 | The influence of the radiation syndrome on cytochrome P450-dependent monooxygenation in rat liver. ( Bleyer, H; Klinger, W; Müller, D; Wölfle, G, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERNAT, P | 1 |
| BRZEK, A | 1 |
| DEDEK, V | 1 |
| ZOUBEK, J | 1 |
| DUBOIS, KP | 2 |
| KINOSHITA, F | 2 |
| Down, JD | 1 |
| Collis, CH | 1 |
| Jeffery, PK | 1 |
| Steel, GG | 1 |
| Black, HS | 1 |
| Chan, JT | 1 |
| Brown, GE | 1 |
| Olson, JJ | 1 |
| Shelley, C | 1 |
| Orr, K | 1 |
| DeLaney, T | 1 |
| Oldfield, EH | 1 |
| Wölfle, G | 1 |
| Bleyer, H | 1 |
| Müller, D | 1 |
| Klinger, W | 1 |
| Takeshita, K | 2 |
| Koldaev, VM | 1 |
| Umayahara, A | 1 |
| Fujii, K | 1 |
| Mattila, MJ | 1 |
| Holsti, LR | 1 |
| Venho, VM | 1 |
| Takki, S | 1 |
1 review available for phenobarbital and Experimental Radiation Injuries
| Article | Year |
|---|---|
[Use of chemical substances in ultrahigh frequency electromagnetic radiation (review of the literature)].
Topics: Animals; Anura; Ascorbic Acid; Atropine; Chlorpromazine; Epinephrine; Ergotamine; Glucose; Humans; M | 1972 |
10 other studies available for phenobarbital and Experimental Radiation Injuries
| Article | Year |
|---|---|
[Changes in the motor activity after pentazole administration in irradiated rats under the influence of phenobarbital inhibition].
Topics: Animals; Motor Activity; Movement; Pentylenetetrazole; Phenobarbital; Radiation Injuries, Experiment | 1960 |
THE EFFECTS OF IONIZING RADIATIONS ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. II. INFLUENCE OF VARIOUS FACTORS ON RADIATION-INDUCED INHIBITION OF THE DEVELOPMENT OF DETOXIFICATION ENZYMES. QUART PROGR REP 50.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Brain; Cholinesterases; Clinical Enzyme Tests; D | 1964 |
THE EFFECTS OF IONIZING RADIATIONS ON THE BIOCHEMISTRY OF MAMMALIAN TISSUES. I. THE INFLUENCE OF X-IRRADIATION AND CHEMICAL AGENTS ON DETOXIFICATION MECHANISMS. QUART PROGR REP 49.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Benzopyrenes; Dactinomycin; Liver; Methylcholant | 1963 |
The effects of anesthetics and misonidazole on the development of radiation-induced lung damage in mice.
Topics: Adrenal Cortex Hormones; Anesthetics; Animals; Lung; Male; Mice; Mice, Inbred CBA; Misonidazole; Nit | 1983 |
Effects of dietary constituents on ultraviolet light-mediated carcinogenesis.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Diet; Disulfiram; Female; Glutathione; Keratosis; M | 1978 |
The cerebral radioprotective effect of alternative barbiturates to pentobarbital.
Topics: Animals; Barbiturates; Brain Neoplasms; Male; Methohexital; Pentobarbital; Phenobarbital; Radiation | 1992 |
The influence of the radiation syndrome on cytochrome P450-dependent monooxygenation in rat liver.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome | 1991 |
Acute death of mice from massive doses of high energy electron.
Topics: Animals; Electrocardiography; Electrons; Female; Mice; Phenobarbital; Radiation Dosage; Radiation In | 1972 |
[Acute death of mice during massive Gamma irradiation. 3].
Topics: Animals; Electrocardiography; Electromyography; Female; Heart Rate; Injections, Intraperitoneal; Mic | 1971 |
Absorption of drugs in vitro from the rat intestine damaged by triparanol or irradiation.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Depression, Chemical; Ethionamide; Female; Intestinal Abs | 1970 |