phenobarbital has been researched along with Experimental Mammary Neoplasms in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "BRCA1 driven triple negative breast cancer (TNBC) has been shown to arise from luminal progenitors yet little is known about how BRCA1 loss-of-function (LOF) and concomitant mutations affect the luminal progenitor cell state." | 1.62 | Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors. ( Bach, K; Caldas, C; Clarke, RB; Greenhalgh, AR; Halim, TYF; Howell, SJ; Kania, K; Khaled, WT; Lazarus, KA; Marioni, JC; Pensa, S; Pinaud, S; Shehata, M; Simões, BM; Stockis, J; Zarocsinceva, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Phoon, YP | 1 |
| Chivukula, IV | 1 |
| Tsoi, YL | 1 |
| Kanatani, S | 1 |
| Uhlén, P | 1 |
| Kuiper, R | 1 |
| Lendahl, U | 1 |
| Bach, K | 1 |
| Pensa, S | 1 |
| Zarocsinceva, M | 1 |
| Kania, K | 1 |
| Stockis, J | 1 |
| Pinaud, S | 1 |
| Lazarus, KA | 1 |
| Shehata, M | 1 |
| Simões, BM | 1 |
| Greenhalgh, AR | 1 |
| Howell, SJ | 1 |
| Clarke, RB | 1 |
| Caldas, C | 1 |
| Halim, TYF | 1 |
| Marioni, JC | 1 |
| Khaled, WT | 1 |
| Shirai, T | 1 |
| Lee, MS | 1 |
| Wang, CY | 1 |
| King, CM | 1 |
| Feuer, G | 3 |
| Kellen, JA | 3 |
| Kovacs, K | 2 |
| Pitot, HC | 1 |
| Ito, N | 1 |
| Porta, EA | 1 |
| Dytioco, S | 1 |
| Aquino, T | 1 |
| Dorado, RD | 1 |
| Ooka, S | 1 |
| Markell, N | 1 |
| Jellinck, PH | 1 |
| Smith, G | 1 |
| Mückter, H | 1 |
| Moré, E | 1 |
1 review available for phenobarbital and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Organ-specific modifying effects of phenobarbital, saccharin and antioxidants on 2-stage chemical carcinogenesis.
Topics: Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogen | 1986 |
10 other studies available for phenobarbital and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Notch activation in the mouse mammary luminal lineage leads to ductal hyperplasia and altered partitioning of luminal cell subtypes.
Topics: Animals; Cell Transformation, Neoplastic; Epithelial Cells; Female; Hyperplasia; Mammary Glands, Ani | 2020 |
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Cell Communication; Cell Differentiation; Cell Transformat | 2021 |
Effects of partial hepatectomy and dietary phenobarbital on liver and mammary tumorigenesis by two N-hydroxy-N-acylaminobiphenyls in female CD rats.
Topics: Aminobiphenyl Compounds; Animals; Body Weight; Female; Hepatectomy; Hydroxamic Acids; Liver Neoplasm | 1981 |
Is there any association between the pharmacologic control of prolactin release and its action on mammary carcinogenesis in the rat?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbon Tetrachloride; Coumarins; Female; Mammary Neoplasm | 1977 |
The stability of events in the natural history of neoplasia.
Topics: Animals; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; | 1977 |
Is there any association between elevated serum prolactin level and mammary adenocarcinoma induced by 7,12-dimethylbenz(alpha)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Coumarins; Female; Li | 1975 |
Evaluation of the effect of glucan on hepatic, renal and mammary tumorigenesis in rats.
Topics: Animals; Diethylnitrosamine; Female; Glucans; Glucose; Hepatectomy; Kidney Neoplasms; Liver Neoplasm | 1986 |
N-ethylmaleimide adduct of 7,12-dimethylbenzanthracene. Properties and metabolism by rat liver microsomes.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Carbon Isotopes; Chromatography, Thin Layer; Enzyme Ind | 1972 |
[Thalidomide and cancer].
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chlormadinone Acetate; Chlorpromazine; Cyclophos | 1966 |
Inhibition and enhancement of mammary tumorigenesis by 7,12-dimethylbenz (a) anthracene in the female sprague-dawley rat.
Topics: Animals; Benz(a)Anthracenes; Coumarins; Enzyme Induction; Female; Glucose-6-Phosphatase; Liver; Mamm | 1974 |