Page last updated: 2024-11-02

phenobarbital and Exanthema

phenobarbital has been researched along with Exanthema in 12 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.

Research Excerpts

ExcerptRelevanceReference
"A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported."8.85Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009)
"A case of propofol infusion syndrome in a patient with respiratory failure and sepsis is reported."4.85Propofol infusion syndrome: case report and literature review. ( Chen, J; Cohen, N; Nadkarni, A; Orsini, J, 2009)
"The antiepileptic drug hypersensitivity syndrome (AHS) is an adverse drug reaction associated with the aromatic antiepileptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), and primidone."4.80Antiepileptic drug hypersensitivity syndrome. ( Schlienger, RG; Shear, NH, 1998)
"The clinical diagnosis of incontinentia pigmenti (stage 1) was secured by histopathology."1.35Therapy resistant neonatal seizures, linear vesicular rash, and unusually early neuroradiological changes: incontinentia pigmenti: a case report, literature review and insight into pathogenesis. ( Gardiner, J; Kaczala, GW; Messer, MA; Poskitt, KJ; Prendiville, JS; Senger, C, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hosohata, K1
Inada, A1
Oyama, S1
Niinomi, I1
Wakabayashi, T1
Iwanaga, K1
Wolski, TP1
Blasick, S1
Blackford, MG1
Orsini, J1
Nadkarni, A1
Chen, J1
Cohen, N1
LEVY, AJ1
Wang, XQ1
Lang, SY1
Shi, XB1
Tian, HJ1
Wang, RF1
Yang, F1
SNEDDON, IB1
LEISHMAN, AW1
Kaczala, GW1
Messer, MA1
Poskitt, KJ1
Prendiville, JS1
Gardiner, J1
Senger, C1
Gupta, R1
Gupta, S1
Vandvik, IH1
Schlienger, RG1
Shear, NH1
Kleine-Natrop, HE1
Schulz, KH1
Schmidt, P1

Reviews

2 reviews available for phenobarbital and Exanthema

ArticleYear
Propofol infusion syndrome: case report and literature review.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, May-15, Volume: 66, Issue:10

    Topics: Adult; Anesthetics, Intravenous; Drug Administration Schedule; Exanthema; Female; Hepatomegaly; Huma

2009
Antiepileptic drug hypersensitivity syndrome.
    Epilepsia, 1998, Volume: 39 Suppl 7

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; D

1998

Other Studies

10 other studies available for phenobarbital and Exanthema

ArticleYear
Adverse Cutaneous Drug Reactions Associated with Old- and New- Generation Antiepileptic Drugs Using the Japanese Pharmacovigilance Database.
    Clinical drug investigation, 2019, Volume: 39, Issue:4

    Topics: Anticonvulsants; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Exanthema; Fem

2019
The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia.
    Clinical pediatrics, 2016, Volume: 55, Issue:14

    Topics: Anticonvulsants; Antipyretics; Drug Hypersensitivity Syndrome; Exanthema; Humans; Infant; Male; Panc

2016
Skin eruption due to phenobarbital among mentally defective epileptic patients.
    American journal of mental deficiency, 1946, Volume: 51, Issue:2

    Topics: Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Hypersensitivity; Phenobarbital

1946
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; Chi

2010
Severe and fatal phenobarbitone eruptions.
    British medical journal, 1952, Jun-14, Volume: 1, Issue:4771

    Topics: Barbiturates; Drug Eruptions; Exanthema; Humans; Phenobarbital

1952
Therapy resistant neonatal seizures, linear vesicular rash, and unusually early neuroradiological changes: incontinentia pigmenti: a case report, literature review and insight into pathogenesis.
    European journal of pediatrics, 2008, Volume: 167, Issue:9

    Topics: Anticonvulsants; Exanthema; Female; Humans; Incontinentia Pigmenti; Infant, Newborn; Phenobarbital;

2008
Exanthematous allergic drug reactions due to four chemically unrelated drugs.
    Dermatology online journal, 2008, Jan-15, Volume: 14, Issue:1

    Topics: Adult; Antibiotics, Antitubercular; Anticonvulsants; Antitubercular Agents; Erythema; Ethambutol; Ex

2008
[Toxic epidermal necrolysis. Epidermolysis necroticans combustiforme].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1967, Jun-01, Volume: 87, Issue:11

    Topics: Child, Preschool; Exanthema; Humans; Male; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome

1967
[Pathomechanic variants of allergic drug induced skin injuries].
    Allergie und Asthma, 1969, Volume: 15, Issue:1

    Topics: Allergens; Aminopyrine; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Exanthema; Femal

1969
[Fixed exanthema due to 3 different drugs with separate localization. Contribution to the problem of barbiturate allergy].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Jul-15, Volume: 42, Issue:14

    Topics: Antipyrine; Barbiturates; Drug Hypersensitivity; Exanthema; Female; Humans; Middle Aged; Phenobarbit

1967