phenobarbital has been researched along with Embryopathies in 15 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 7.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 3.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| "Treatment with phenobarbital resulted in substantial improvement in the number of seizure episodes, however fine seizure-like movement continued in both of the hands, feet and in the tongue until the five-month follow-up." | 1.35 | Prenatal diagnosis of fetal seizure: a case report. ( Huh, CY; Jung, E; Lee, BY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jung, E | 1 |
| Lee, BY | 1 |
| Huh, CY | 1 |
| LAWRENCE, A | 1 |
| Firinu, C | 1 |
| Meloni, T | 1 |
| Milia, S | 1 |
| Virdis, P | 1 |
| Lo Dico, G | 1 |
| Stoppelli, I | 1 |
| Fabris, C | 1 |
| Prandi, GM | 1 |
| Berardi, V | 1 |
| Santoro, MA | 1 |
| Martano, C | 1 |
| Mombrò, M | 1 |
| Abdel-Rahman, AM | 1 |
| Rosenberg, AA | 1 |
| Muto, R | 1 |
| Ohashi, H | 1 |
| Zackai, EH | 1 |
| Mellman, WJ | 1 |
| Neiderer, B | 1 |
| Hanson, JW | 1 |
| Kopecky, P | 1 |
| Schwarz, I | 1 |
| Schwenzel, W | 1 |
| Ostrow, JD | 1 |
| Reynolds, JW | 1 |
| Behrman, RE | 1 |
| Fisher, D | 1 |
| Paton, JB | 1 |
| Keller, J | 1 |
| Harbison, RD | 1 |
| Becker, BA | 1 |
| O'Leary, JA | 1 |
| Feldman, M | 1 |
| Switzer, HE | 1 |
| Rosen, MG | 2 |
| McLaughlin, A | 2 |
6 reviews available for phenobarbital and Embryopathies
| Article | Year |
|---|---|
[The newborn infant of the drug-dependent mother. Review of literature and personal case reports].
Topics: Adult; Female; Fetal Diseases; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases | 1980 |
Prevention of intraventricular hemorrhage in the premature infant.
Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Fetal Diseases; Humans; | 1994 |
[Fetal barbiturate effects].
Topics: Anticonvulsants; Female; Fetal Diseases; Humans; Infant, Newborn; Phenobarbital; Pregnancy | 2001 |
Photochemical and biochemical basis of the treatment of neonatal jaundice.
Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Erythroblastosis, Fetal; Eye Injuries; Female; Fetal | 1972 |
The use of drugs in influencing human fetal metabolism.
Topics: Adrenocortical Hyperfunction; Animals; Blood Transfusion, Intrauterine; Congenital Hypothyroidism; E | 1974 |
In utero disease and the newborn infant.
Topics: Acid-Base Equilibrium; Acidosis; Amniotic Fluid; Animals; Bilirubin; Birth Weight; Electrocardiograp | 1970 |
9 other studies available for phenobarbital and Embryopathies
| Article | Year |
|---|---|
Prenatal diagnosis of fetal seizure: a case report.
Topics: Female; Fetal Diseases; Humans; Infant, Newborn; Karyotyping; Magnetic Resonance Imaging; Male; Phen | 2008 |
ANTI-EPILEPTIC DRUGS AND THE FOETUS.
Topics: Barbiturates; Epilepsy; Female; Fetal Diseases; Fetus; Phenobarbital; Phenytoin; Pregnancy; Pregnanc | 1963 |
[Prenatal prevention of hyperbilirubinemia due to G6PD deficiency].
Topics: Adult; Female; Fetal Diseases; Glucosephosphate Dehydrogenase Deficiency; Humans; Hyperbilirubinemia | 1983 |
The fetal trimethadione syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental | 1975 |
[Antepartal phenobarbital therapy for the improvement of fetal bilirubin conjugation].
Topics: Erythroblastosis, Fetal; Female; Fetal Diseases; Gestational Age; Humans; Infant, Newborn; Jaundice, | 1975 |
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fet | 1970 |
P henobarbital-Dilantin treatment of the intrauterine patient.
Topics: Enzyme Induction; Epilepsy; Erythroblastosis, Fetal; Female; Fetal Diseases; Humans; Infant, Newborn | 1970 |
Maternal and fetal electroencephalography in the guinea pig.
Topics: Animals; Electroencephalography; Female; Fetal Diseases; Fetus; Guinea Pigs; Hypoxia, Brain; Phenoba | 1966 |
Maternal and fetal electroencephalography in the guinea pig.
Topics: Animals; Electroencephalography; Female; Fetal Diseases; Fetus; Guinea Pigs; Hypoxia, Brain; Phenoba | 1966 |