Page last updated: 2024-11-02

phenobarbital and Embryopathies

phenobarbital has been researched along with Embryopathies in 15 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"Three families are described in which each of the mothers took trimethadione during pregnancy."7.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
"Three families are described in which each of the mothers took trimethadione during pregnancy."3.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
"Treatment with phenobarbital resulted in substantial improvement in the number of seizure episodes, however fine seizure-like movement continued in both of the hands, feet and in the tongue until the five-month follow-up."1.35Prenatal diagnosis of fetal seizure: a case report. ( Huh, CY; Jung, E; Lee, BY, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jung, E1
Lee, BY1
Huh, CY1
LAWRENCE, A1
Firinu, C1
Meloni, T1
Milia, S1
Virdis, P1
Lo Dico, G1
Stoppelli, I1
Fabris, C1
Prandi, GM1
Berardi, V1
Santoro, MA1
Martano, C1
Mombrò, M1
Abdel-Rahman, AM1
Rosenberg, AA1
Muto, R1
Ohashi, H1
Zackai, EH1
Mellman, WJ1
Neiderer, B1
Hanson, JW1
Kopecky, P1
Schwarz, I1
Schwenzel, W1
Ostrow, JD1
Reynolds, JW1
Behrman, RE1
Fisher, D1
Paton, JB1
Keller, J1
Harbison, RD1
Becker, BA1
O'Leary, JA1
Feldman, M1
Switzer, HE1
Rosen, MG2
McLaughlin, A2

Reviews

6 reviews available for phenobarbital and Embryopathies

ArticleYear
[The newborn infant of the drug-dependent mother. Review of literature and personal case reports].
    Minerva pediatrica, 1980, May-31, Volume: 32, Issue:10

    Topics: Adult; Female; Fetal Diseases; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases

1980
Prevention of intraventricular hemorrhage in the premature infant.
    Clinics in perinatology, 1994, Volume: 21, Issue:3

    Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Fetal Diseases; Humans;

1994
[Fetal barbiturate effects].
    Ryoikibetsu shokogun shirizu, 2001, Issue:33

    Topics: Anticonvulsants; Female; Fetal Diseases; Humans; Infant, Newborn; Phenobarbital; Pregnancy

2001
Photochemical and biochemical basis of the treatment of neonatal jaundice.
    Progress in liver diseases, 1972, Volume: 4

    Topics: Animals; Bile; Bile Acids and Salts; Bilirubin; Erythroblastosis, Fetal; Eye Injuries; Female; Fetal

1972
The use of drugs in influencing human fetal metabolism.
    Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:3

    Topics: Adrenocortical Hyperfunction; Animals; Blood Transfusion, Intrauterine; Congenital Hypothyroidism; E

1974
In utero disease and the newborn infant.
    Advances in pediatrics, 1970, Volume: 17

    Topics: Acid-Base Equilibrium; Acidosis; Amniotic Fluid; Animals; Bilirubin; Birth Weight; Electrocardiograp

1970

Other Studies

9 other studies available for phenobarbital and Embryopathies

ArticleYear
Prenatal diagnosis of fetal seizure: a case report.
    Journal of Korean medical science, 2008, Volume: 23, Issue:5

    Topics: Female; Fetal Diseases; Humans; Infant, Newborn; Karyotyping; Magnetic Resonance Imaging; Male; Phen

2008
ANTI-EPILEPTIC DRUGS AND THE FOETUS.
    British medical journal, 1963, Nov-16, Volume: 2, Issue:5367

    Topics: Barbiturates; Epilepsy; Female; Fetal Diseases; Fetus; Phenobarbital; Phenytoin; Pregnancy; Pregnanc

1963
[Prenatal prevention of hyperbilirubinemia due to G6PD deficiency].
    Minerva ginecologica, 1983, Volume: 35, Issue:5

    Topics: Adult; Female; Fetal Diseases; Glucosephosphate Dehydrogenase Deficiency; Humans; Hyperbilirubinemia

1983
The fetal trimethadione syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental

1975
[Antepartal phenobarbital therapy for the improvement of fetal bilirubin conjugation].
    Archiv fur Gynakologie, 1975, Nov-18, Volume: 219, Issue:1-4

    Topics: Erythroblastosis, Fetal; Female; Fetal Diseases; Gestational Age; Humans; Infant, Newborn; Jaundice,

1975
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fet

1970
P henobarbital-Dilantin treatment of the intrauterine patient.
    The Journal of reproductive medicine, 1970, Volume: 5, Issue:2

    Topics: Enzyme Induction; Epilepsy; Erythroblastosis, Fetal; Female; Fetal Diseases; Humans; Infant, Newborn

1970
Maternal and fetal electroencephalography in the guinea pig.
    American journal of obstetrics and gynecology, 1966, Aug-01, Volume: 95, Issue:7

    Topics: Animals; Electroencephalography; Female; Fetal Diseases; Fetus; Guinea Pigs; Hypoxia, Brain; Phenoba

1966
Maternal and fetal electroencephalography in the guinea pig.
    American journal of obstetrics and gynecology, 1966, Aug-01, Volume: 95, Issue:7

    Topics: Animals; Electroencephalography; Female; Fetal Diseases; Fetus; Guinea Pigs; Hypoxia, Brain; Phenoba

1966