Page last updated: 2024-11-02

phenobarbital and Dizziness

phenobarbital has been researched along with Dizziness in 7 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.

Research Excerpts

ExcerptRelevanceReference
"To investigate the current status of epilepsy treatment and the efficacy and adverse effects of phenobarbital therapy in rural areas of Northern China."9.24Current status of epilepsy treatment and efficacy of standard phenobarbital therapy in rural areas of Northern China. ( Lin, W; Luo, N; Wang, Z; Yu, J, 2017)
"To investigate the current status of epilepsy treatment and the efficacy and adverse effects of phenobarbital therapy in rural areas of Northern China."5.24Current status of epilepsy treatment and efficacy of standard phenobarbital therapy in rural areas of Northern China. ( Lin, W; Luo, N; Wang, Z; Yu, J, 2017)
"One-hundred eighty patients with partial or idiopathic generalized nonabsence epilepsy, aged 6 to 65 years, requiring initiation of treatment with carbamazepine (CBZ), valproate (VPA), phenytoin (PHT), phenobarbital (PB), or primidone (PRM) were randomly allocated to two groups according to an open, prospective parallel-group design."5.09A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy. ( Bartoli, A; Cian, P; Fattore, C; Gatti, G; Jannuzzi, G; Monaco, F; Perucca, E, 2000)
"Pretreatment with phenobarbital can minimize the occurrence of intolerable adverse events associated with the introduction of primidone."2.69The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity. ( Frey, M; Kanner, AM; Parra, J, 2000)
"Perampanel (PER) is a new antiepileptic drug (AED) with a novel mechanism of action."1.51Clinical profiles associated with serum perampanel concentrations in children with refractory epilepsy. ( Ishikawa, N; Kobayashi, M; Kobayashi, Y; Tani, H; Tateishi, Y, 2019)
"This study explored the adverse effect (AE) profile of phenobarbital (PB) among patients with active convulsive epilepsy (ACE) from resource-poor areas."1.43A preliminary observation of the adverse effects of phenobarbital among patients with convulsive epilepsy in rural West China. ( Chen, D; Chen, T; Deng, Y; He, J; He, L; Li, Y; Liu, L; Mu, J; Si, Y; Tian, L; Zhou, D, 2016)
" sex, excess intracranial flow of metrizamide and myelographic blockage were not shown to have a significant influence on the adverse reactions."1.27Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography. ( du Boulay, GH; Paul, E; Yu, YL, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishikawa, N1
Tateishi, Y1
Tani, H1
Kobayashi, Y1
Kobayashi, M1
Si, Y1
Liu, L1
Tian, L1
Mu, J1
Chen, D1
Chen, T1
Deng, Y1
He, J1
Li, Y1
He, L1
Zhou, D1
Yu, J1
Luo, N1
Wang, Z1
Lin, W1
Thibodeau, LG1
Ferrera, PC1
Jannuzzi, G1
Cian, P1
Fattore, C1
Gatti, G1
Bartoli, A1
Monaco, F1
Perucca, E1
Kanner, AM1
Parra, J1
Frey, M1
Yu, YL1
du Boulay, GH1
Paul, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study on Long-term Outcome and Potential Usefulness fo an Intervention Aimed at Reducing Adverse Effects in Patients With Refractory Epilepsy[NCT03939507]1,000 participants (Actual)Interventional2006-11-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for phenobarbital and Dizziness

ArticleYear
Current status of epilepsy treatment and efficacy of standard phenobarbital therapy in rural areas of Northern China.
    The International journal of neuroscience, 2017, Volume: 127, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; China; Dizzine

2017
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy.
    Epilepsia, 2000, Volume: 41, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dizziness; Drug Administration Sched

2000
The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity.
    Epilepsia, 2000, Volume: 41, Issue:10

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Child; Child, Preschool; Dizziness; Dose-Response Relation

2000

Other Studies

4 other studies available for phenobarbital and Dizziness

ArticleYear
Clinical profiles associated with serum perampanel concentrations in children with refractory epilepsy.
    Epilepsy & behavior : E&B, 2019, Volume: 94

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dizziness; Drug Resistant Epile

2019
A preliminary observation of the adverse effects of phenobarbital among patients with convulsive epilepsy in rural West China.
    Epilepsy & behavior : E&B, 2016, Volume: 54

    Topics: Adolescent; Adult; Aged; China; Cohort Studies; Dizziness; Epilepsy, Generalized; Female; Follow-Up

2016
Nonconvulsive status epilepticus.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:7

    Topics: Anticonvulsants; Dizziness; Electroencephalography; Emergency Service, Hospital; Epilepsy, Tonic-Clo

1997
Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography.
    Neuroradiology, 1986, Volume: 28, Issue:4

    Topics: Adult; Aged; Aging; Confusion; Dizziness; Headache; Humans; Metrizamide; Middle Aged; Myelography; N

1986