phenobarbital has been researched along with Disease, Pulmonary in 20 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Findings of lung granulomas are not rare but their etiology may be embarrassing in autoptic and especially in bioptic material which is shown in two such cases: a 19-year old drug addict man practising intravenous administration of Alnagon pills and a 54-year old woman working with acrylonitrile fibres." | 3.68 | [Granulomatous processes in the lungs]. ( Dĕdic, K; Horácek, J, 1990) |
| "Phenobarbital pretreatment did not substantially alter the time course of toxicity induced with 20 mg/l monocrotaline water." | 1.28 | Dose-response relationship in intoxication by the pyrrolizidine alkaloid monocrotaline. ( Hubbard, AK; Huxtable, RJ; Shubat, PJ, 1989) |
| " It is well established that the pneumotoxicity of MCT depends on its hepatic bioactivation to monocrotaline pyrrole (MCTP) and perhaps other toxic metabolites." | 1.27 | Effect of a mixed function oxidase inducer and inhibitor on monocrotaline pyrrole pneumotoxicity. ( Bruner, LH; Carpenter, LJ; Hamlow, P; Roth, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| JARNIOU, AP | 1 |
| CHAMBATTE, C | 1 |
| Levene, M | 1 |
| Villaveces, JW | 1 |
| Breeze, RG | 1 |
| Laegreid, WW | 1 |
| Olcott, BM | 1 |
| Lourwood, DL | 1 |
| Kacew, S | 1 |
| Narbaitz, R | 1 |
| Ruddick, JA | 1 |
| Villeneuve, DC | 1 |
| Gadberry, MG | 1 |
| DeNicola, DB | 1 |
| Carlson, GP | 1 |
| Horácek, J | 1 |
| Dĕdic, K | 1 |
| Elovaara, E | 1 |
| Vainio, H | 1 |
| Aitio, A | 1 |
| Shubat, PJ | 1 |
| Hubbard, AK | 1 |
| Huxtable, RJ | 1 |
| Bruner, LH | 1 |
| Carpenter, LJ | 1 |
| Hamlow, P | 1 |
| Roth, RA | 1 |
| Lequesne, M | 1 |
| Lombroso, CT | 1 |
| Reid, WD | 1 |
| Ilett, KF | 1 |
| Glick, JM | 1 |
| Krishna, G | 1 |
| Rosenow, EC | 1 |
| Hughes, RW | 1 |
| Nolte, H | 1 |
| von Schnakenburg, K | 1 |
| Lal, S | 1 |
| Bhalla, KK | 1 |
| Davey, AJ | 1 |
| Smythe, PM | 1 |
| Dezoteux, H | 1 |
| Vinceneux, P | 1 |
| Behnke, RH | 1 |
2 reviews available for phenobarbital and Disease, Pulmonary
| Article | Year |
|---|---|
Minimising neonatal brain injury: how research in the past five years has changed my clinical practice.
Topics: Animals; Birth Injuries; Brain Diseases; Dexamethasone; Disease Models, Animal; Ethamsylate; Humans; | 2007 |
The treatment of status epilepticus.
Topics: Anti-Bacterial Agents; Anticonvulsants; Barbiturates; Brain Edema; Central Nervous System Diseases; | 1974 |
1 trial available for phenobarbital and Disease, Pulmonary
| Article | Year |
|---|---|
Slow release salbutamol and Tedral in the treatment of reversible airways obstruction.
Topics: Adolescent; Adult; Aged; Amino Alcohols; Bronchodilator Agents; Clinical Trials as Topic; Delayed-Ac | 1971 |
17 other studies available for phenobarbital and Disease, Pulmonary
| Article | Year |
|---|---|
[The use of 7438 R. P. in pneumophtysiology].
Topics: Codeine; Humans; Lung Diseases; Muscle Relaxants, Central; Opioid-Related Disorders; Phenobarbital; | 1959 |
Food emulsion therapy: an adverse reaction.
Topics: Adult; Allergens; Desensitization, Immunologic; Diet Therapy; Emulsions; Ephedrine; Erythromycin; Fo | 1967 |
Role of metabolism in the immediate effects and pneumotoxicity of 3-methylindole in goats.
Topics: Animals; Biotransformation; Female; Glycerol; Goats; Hemolysis; Indoles; Infusions, Parenteral; Lung | 1984 |
Comment on ephedrine-phenobarbital formulations.
Topics: Drug Combinations; Ephedrine; Humans; Lung Diseases; Phenobarbital | 1984 |
Role of drug metabolism in protection against chlorphentermine-induced pulmonary phospholipidosis in adult rat.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Body Weight; Chlorphentermine; Cytochrome P | 1981 |
Pneumotoxicity and hepatotoxicity of styrene and styrene oxide.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; C | 1996 |
[Granulomatous processes in the lungs].
Topics: Acrylonitrile; Adult; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Granuloma; Humans; Lung | 1990 |
Pulmonary toxicity of inhaled styrene in acetone-, phenobarbital- and 3-methylcholanthrene-treated rats.
Topics: Acetone; Animals; Body Weight; Cytochrome P-450 Enzyme System; Glutathione; Lung; Lung Diseases; Mal | 1990 |
Dose-response relationship in intoxication by the pyrrolizidine alkaloid monocrotaline.
Topics: Administration, Oral; Animals; Bronchoalveolar Lavage Fluid; Cardiomegaly; Dose-Response Relationshi | 1989 |
Effect of a mixed function oxidase inducer and inhibitor on monocrotaline pyrrole pneumotoxicity.
Topics: Animals; Enzyme Induction; Heart; Lung Diseases; Magnetic Resonance Spectroscopy; Mass Spectrometry; | 1986 |
[Etiology and pathogenesis of algodystrophies].
Topics: Antitubercular Agents; Cardiovascular Diseases; Extremities; Humans; Infections; Lung Diseases; Nerv | 1968 |
Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis.
Topics: Animals; Autoradiography; Bromine; Bronchial Diseases; Carbon Isotopes; Chemical and Drug Induced Li | 1973 |
Progress in bronchoesophageal endoscopy.
Topics: Biopsy; Bronchoscopes; Bronchoscopy; Child; Deglutition Disorders; Diazepam; Esophageal Diseases; Es | 1973 |
[Morphological and pharmacological-toxicological aspects of hyperoxia].
Topics: Aminobutyrates; Animals; Atmospheric Pressure; Brain Diseases; Diazepam; Ganglia; Humans; Lung; Lung | 1973 |
Treatment of tetanus neonatorum.
Topics: Humans; Humidity; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intramuscular; Injections, | 1966 |
[The lung and massive intentional poisoning by organo-phosphoric substances].
Topics: Adolescent; Adult; DDT; Female; Humans; Insecticides; Lung; Lung Diseases; Male; Parasympatholytics; | 1970 |
Indiana University School of Medicine. Clinicopathologic conference.
Topics: Aged; Diagnosis, Differential; Female; Humans; Hyaline Membrane Disease; Infant, Newborn; Intubation | 1968 |