phenobarbital has been researched along with Diabetes Mellitus in 7 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the effects of phenobarbital, an inducer, on plasma glucose and serum immunoreactive insulin levels and on hepatic glucose and drug metabolism using an animal model of non-insulin dependent diabetes mellitus." | 3.67 | Effects of enzyme induction therapy on glucose and drug metabolism in obese mice model of non-insulin dependent diabetes mellitus. ( Huupponen, R; Karvonen, I; Sotaniemi, EA; Stenbäck, FG; Stengård, JH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CORTET, P | 1 |
| FRANC, B | 1 |
| SYNEK, J | 1 |
| Scott, J | 1 |
| Henderson, AD | 1 |
| Poffenbarger, PL | 1 |
| Karvonen, I | 1 |
| Stengård, JH | 1 |
| Huupponen, R | 1 |
| Stenbäck, FG | 1 |
| Sotaniemi, EA | 1 |
| Garland, RC | 1 |
| Cori, CF | 1 |
| Chang, HW | 1 |
| Redman, DR | 1 |
| Prescott, LF | 1 |
| Fahim, MS | 1 |
| Hall, DG | 1 |
| Fahim, Z | 1 |
7 other studies available for phenobarbital and Diabetes Mellitus
| Article | Year |
|---|---|
[Resuscitation and alkalinization. Treatment of grave barbiturate poisoning in diabetic].
Topics: Barbiturates; Diabetes Complications; Diabetes Mellitus; Humans; Phenobarbital; Resuscitation | 1960 |
[Effect of phenobarbital on estrus].
Topics: Animals; Barbital; Diabetes Mellitus; Estrus; Phenobarbital | 1950 |
Genetic control of tolbutamide metabolism in humans.
Topics: Adolescent; Adult; Aged; Carrier Proteins; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Ethano | 1979 |
Effects of enzyme induction therapy on glucose and drug metabolism in obese mice model of non-insulin dependent diabetes mellitus.
Topics: Animals; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabete | 1989 |
Relipidation of phospholipid-depleted microsomal particles with high glucose 6-phosphatase activity.
Topics: Cell Fractionation; Centrifugation, Density Gradient; Deoxycholic Acid; Diabetes Mellitus; Endoplasm | 1974 |
Failure of induction of liver microsomal enzymes by tolbutamide in maturity-onset diabetics.
Topics: Aged; Diabetes Mellitus; Enzyme Induction; Female; Half-Life; Humans; Male; Microsomes, Liver; Middl | 1973 |
Urinary D-glucaric acid. An index of heparin microsomal enzyme activity in human females.
Topics: Adipates; Diabetes Mellitus; Enzyme Induction; Female; Humans; Liver; Microsomes; Middle Aged; Pheno | 1969 |