Page last updated: 2024-11-02

phenobarbital and Diabetes Mellitus, Type 1

phenobarbital has been researched along with Diabetes Mellitus, Type 1 in 5 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.

Research Excerpts

ExcerptRelevanceReference
"To report a case of type 1 diabetes mellitus (T1DM) in a child with phenobarbital hypersensitivity syndrome with an emphasis on the clinical presentation, diagnostic modalities and treatment options."7.74Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome. ( Fu, JF; Liang, L; Zou, CC, 2008)
"To report a case of type 1 diabetes mellitus (T1DM) in a child with phenobarbital hypersensitivity syndrome with an emphasis on the clinical presentation, diagnostic modalities and treatment options."3.74Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome. ( Fu, JF; Liang, L; Zou, CC, 2008)
"In the next three months, two recurrences of this syndrome were verified and successfully treated in a similar manner."1.25Recurrent hyperosmolar nonketotic episodes in a young diabetic. ( Ginsberg-Fellner, F; Primack, WA, 1975)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Kort, S1
Keszthelyi, D1
Masclee, AA1
Zou, CC1
Liang, L1
Fu, JF1
Korobkin, R1
Ginsberg-Fellner, F1
Primack, WA1
Shcherbina, RV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Innate and Adaptive Immunity After Acute Myocardial Infarction BATTLE-AMI Study (B And T Types of Lymphocytes Evaluation in Acute Myocardial Infarction)[NCT02428374]Phase 4300 participants (Anticipated)Interventional2015-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenobarbital and Diabetes Mellitus, Type 1

ArticleYear
Leaky gut and diabetes mellitus: what is the link?
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2011, Volume: 12, Issue:6

    Topics: Animals; Cholera Toxin; Cytokines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet; Hapto

2011

Other Studies

4 other studies available for phenobarbital and Diabetes Mellitus, Type 1

ArticleYear
Type 1 diabetes mellitus in a child with phenobarbital hypersensitivity syndrome.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:4

    Topics: Adrenal Cortex Hormones; Child, Preschool; Diabetes Mellitus, Type 1; Drug Hypersensitivity; Female;

2008
Active hemiparesis in juvenile insulin-dependent diabetes mellitus (JIDDM)
    Neurology, 1980, Volume: 30, Issue:2

    Topics: Diabetes Mellitus, Type 1; Female; Headache; Hemiplegia; Humans; Infant; Phenobarbital

1980
Recurrent hyperosmolar nonketotic episodes in a young diabetic.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:2

    Topics: Blood Glucose; Chlorides; Dehydration; Diabetes Mellitus, Type 1; Diabetic Coma; Female; Glucose; Hu

1975
[Use of luminal in children with labile diabetes mellitus].
    Voprosy okhrany materinstva i detstva, 1971, Volume: 16, Issue:4

    Topics: Adolescent; Child; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Humans; Male; Phenobarb

1971