phenobarbital has been researched along with Dermatitis Medicamentosa in 48 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 7.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| "The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported." | 6.38 | A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992) |
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 3.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| "The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported." | 2.38 | A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992) |
| "This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs." | 1.32 | [Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004) |
| "Phenobarbital has a high potential to elicit adverse reactions including severe skin eruptions and systemic involvements among the worldwide-prescribed drugs." | 1.31 | Characterization of drug-specific T cells in phenobarbital-induced eruption. ( Hashizume, H; Takigawa, M; Tokura, Y, 2002) |
| "Phenobarbital was the most effective anticonvulsant drug in this patient." | 1.30 | [Successful induction of tolerance in an epilepsy patient with phenobarbital allergy]. ( Fröscher, W; Kleinhans, D, 1998) |
| "He later developed the acquired immunodeficiency syndrome and serological tests suggested that it was a congenital HIV-I infection." | 1.28 | Erythema multiforme major in a 2-month-old child with human immunodeficiency virus (HIV) infection. ( Salomon, D; Saurat, JH, 1990) |
| "The laboratory findings revealed leukocytosis with atypical lymphocytes, eosinophilia and altered liver function." | 1.27 | [Hypersensitivity syndrome caused by phenytoins and phenobarbital]. ( Azulay, DR; Azulay, RD; Fonseca, JC; Rozembau, I, 1984) |
| "Forty patients having fixed drug eruptions were subjected to provocation tests." | 1.26 | Drugs causing fixed eruptions. ( Pasricha, JS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (47.92) | 18.7374 |
| 1990's | 13 (27.08) | 18.2507 |
| 2000's | 6 (12.50) | 29.6817 |
| 2010's | 6 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Özkaya, E | 1 |
| Kutlay, A | 1 |
| Brizendine, CE | 1 |
| Naik, PJ | 1 |
| Higuchi, T | 1 |
| Satoh, T | 1 |
| Yokozeki, H | 1 |
| Chadly, Z | 1 |
| Aouam, K | 1 |
| Chaabane, A | 1 |
| Belhadjali, H | 1 |
| Abderrazzak Boughattas, N | 1 |
| Zili, JE | 1 |
| Sasaki, N | 1 |
| Baba, S | 1 |
| Takahashi, S | 1 |
| Itou, H | 1 |
| Kowada, K | 1 |
| Shikanai, T | 1 |
| Nakamura, Y | 1 |
| Yamauchi, K | 1 |
| Inoue, H | 1 |
| Sawai, T | 1 |
| Taillia, H | 1 |
| Alla, P | 1 |
| Fournier, B | 1 |
| Bounolleau, P | 1 |
| Ouologem, M | 1 |
| Ricard, D | 1 |
| Sallansonnet-Froment, M | 1 |
| de Greslan, T | 1 |
| Renard, JL | 1 |
| Tan, C | 1 |
| Zhu, WY | 1 |
| Bevier, DE | 1 |
| Miller, MA | 1 |
| Rohleder, JJ | 1 |
| Wozniak, AD | 1 |
| MORRIS, GE | 1 |
| COHEN, JD | 1 |
| CH'EN, CC | 1 |
| MA, SK | 1 |
| HARTMAN, DL | 1 |
| DICKEY, RF | 1 |
| DUPONT, V | 1 |
| MARGAIRAZ, A | 1 |
| GOGUEL, A | 1 |
| TURPIN, R | 1 |
| CAILLE, B | 1 |
| BRICOUT, F | 1 |
| LAFOURCADE, J | 1 |
| CRUVEILLER, J | 1 |
| KESSELER, A | 1 |
| JOLY, C | 1 |
| SNEDDON, IB | 1 |
| LEISHMAN, AW | 1 |
| Papp, Z | 1 |
| Török, L | 1 |
| Criado, PR | 1 |
| Criado, RF | 1 |
| Vasconcellos, C | 1 |
| Pegas, JR | 1 |
| Cera, PC | 1 |
| Fonseca, JC | 1 |
| Azulay, DR | 1 |
| Rozembau, I | 1 |
| Azulay, RD | 1 |
| Fernández de Corres, L | 1 |
| Leanizbarrutia, I | 1 |
| Muñoz, D | 1 |
| Naranjo, CA | 1 |
| Kwok, MC | 1 |
| Lanctôt, KL | 1 |
| Zhao, HP | 1 |
| Spielberg, SP | 1 |
| Shear, NH | 1 |
| Sakai, C | 1 |
| Takagi, T | 1 |
| Oguro, M | 1 |
| Tanabe, N | 1 |
| Wakatsuki, S | 1 |
| Labandeira García, J | 1 |
| Gonzalez, FJ | 1 |
| Carvajal, MJ | 1 |
| del Pozo, V | 1 |
| Lahoz, C | 1 |
| Santamaria, L | 1 |
| Blanca, M | 1 |
| Juarez, C | 1 |
| Fröscher, W | 1 |
| Kleinhans, D | 1 |
| Arima, M | 1 |
| Kanoh, T | 1 |
| Yamasaki, A | 1 |
| Matsuda, S | 1 |
| Kasuya, H | 1 |
| Sunayama, S | 1 |
| Kawai, S | 1 |
| Okada, R | 1 |
| Chapman, MS | 1 |
| Zug, KA | 1 |
| Lewis, LD | 1 |
| Lachgar, T | 1 |
| Touil, Y | 1 |
| Ducote, JM | 1 |
| Coates, JR | 1 |
| Dewey, CW | 1 |
| Kennis, RA | 1 |
| Hashizume, H | 1 |
| Takigawa, M | 1 |
| Tokura, Y | 1 |
| Weisburst, M | 1 |
| Self, T | 1 |
| Peace, R | 1 |
| Cooper, J | 1 |
| Dobozy, A | 1 |
| Hunyadi, J | 1 |
| Kenderessy, AS | 1 |
| Pasricha, JS | 1 |
| Livingston, S | 1 |
| Pruce, I | 1 |
| Pauli, LL | 1 |
| Livingston, HL | 1 |
| Nagata, T | 1 |
| Kawamura, N | 1 |
| Motoyama, T | 1 |
| Miyake, M | 1 |
| Yoden, A | 1 |
| Yoshikawa, K | 1 |
| Oguni, T | 1 |
| Yamasiro, K | 1 |
| Mino, M | 1 |
| Mion, N | 1 |
| Fusade, T | 1 |
| Mathelier-Fusade, P | 1 |
| Joly, P | 1 |
| Belanyi, P | 1 |
| Balguerie, X | 1 |
| Chosidow, O | 1 |
| Thomine, E | 1 |
| Lauret, P | 1 |
| Sawaishi, Y | 1 |
| Komatsu, K | 1 |
| Takeda, O | 1 |
| Tazawa, Y | 1 |
| Takahashi, I | 1 |
| Hayasaka, K | 1 |
| Takada, G | 1 |
| Kleier, RS | 1 |
| Breneman, DL | 1 |
| Boiko, S | 1 |
| Salomon, D | 1 |
| Saurat, JH | 2 |
| Savich, RD | 1 |
| Traisman, HS | 1 |
| Naik, RP | 1 |
| Srinivas, CR | 1 |
| Das, PC | 1 |
| Pigatto, PD | 1 |
| Morelli, M | 1 |
| Polenghi, MM | 1 |
| Mozzanica, N | 1 |
| Altomare, GF | 1 |
| Savchak, VI | 1 |
| Hassett, JM | 1 |
| Doolittle, T | 1 |
| Molloy, M | 1 |
| Lalka, D | 1 |
| Pagliaro, L | 1 |
| Campesi, G | 1 |
| Aguglia, F | 1 |
| Adams, RM | 1 |
| Farber, EM | 1 |
| Kleine-Natrop, HE | 1 |
| Bakshi, S | 1 |
| Bhakoo, ON | 1 |
| Burtin, CJ | 1 |
| Soubrane, CB | 1 |
| Paupe, JR | 1 |
| Lüders, D | 1 |
3 reviews available for phenobarbital and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Suppositories for fever as a major risk for phenobarbital-induced fixed drug eruption in children.
Topics: Child; Child, Preschool; Drug Eruptions; Female; Fever; Humans; Male; Phenobarbital; Suppositories | 2017 |
A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion.
Topics: Child, Preschool; Diagnosis, Differential; Drug Eruptions; Eosinophils; Epilepsy; Female; Histiocyte | 1992 |
[The pros and cons of luminal teatment of hyperbilirubinemia].
Topics: Adrenocorticotropic Hormone; Animals; Bilirubin; Central Nervous System; Cholesterol; Drug Eruptions | 1970 |
45 other studies available for phenobarbital and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital.
Topics: Adult; Drug Eruptions; Drug Substitution; Eosinophilia; Female; Humans; Phenobarbital; Phenytoin; Va | 2013 |
Using CD40 ligand expression to detect antigen-specific T cells in patients with drug eruptions.
Topics: Aged; Anticonvulsants; Biomarkers; Carbamazepine; CD4-Positive T-Lymphocytes; CD40 Ligand; Cells, Cu | 2014 |
A patch test confirmed phenobarbital-induced fixed drug eruption in a child.
Topics: Child; Cross Reactions; Drug Eruptions; Female; Humans; Patch Tests; Phenobarbital | 2014 |
[Case of systemic lupus erythematosus occurring after induced abortion and drug eruption].
Topics: Abortion, Induced; Adult; Anticonvulsants; Diagnosis, Differential; Drug Eruptions; Female; Humans; | 2008 |
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 2009 |
Annular fixed drug eruption.
Topics: Adult; Anticonvulsants; Drug Eruptions; Foot Dermatoses; Humans; Male; Phenobarbital | 2010 |
Pathology in practice. Superficial necrolytic dermatitis.
Topics: Amino Acids; Animals; Anticonvulsants; Dog Diseases; Dogs; Drug Eruptions; Foot Diseases; Male; Phen | 2010 |
Cross-sensitivity to diphenylhydantoin sodium and to phenobarbital.
Topics: Barbiturates; Drug Eruptions; Humans; Hydantoins; Phenobarbital; Phenytoin; Sodium | 1953 |
Drug eruptions due to phenobarbital (luminal): report of 16 cases.
Topics: Drug Eruptions; Humans; Phenobarbital | 1957 |
PHOTODERMATITIS INDUCED BY DRUGS. II. PHOTODERMATITIS MEDICAMENTOSA.
Topics: Anti-Bacterial Agents; Benzoates; Chlorothiazide; Diphenhydramine; Drug Eruptions; Estrogens; Geriat | 1964 |
[SOME EXAMPLES OF "PSEUDO-INFECTIOUS" PICTURES INDUCED BY DRUGS].
Topics: Adolescent; Anticonvulsants; Arsenicals; Aspirin; Barbiturates; Diagnosis, Differential; Drug Erupti | 1964 |
[ERYTHEMA MULTIFORME AND REOVIRUS INFECTION].
Topics: Animals; Child; Drug Eruptions; Erythema Multiforme; Humans; Phenobarbital; Reoviridae; Reoviridae I | 1965 |
Severe and fatal phenobarbitone eruptions.
Topics: Barbiturates; Drug Eruptions; Exanthema; Humans; Phenobarbital | 1952 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug | 2004 |
Drug-induced hypersensitivity syndrome due to anticonvulsants in a two-year-old boy.
Topics: Anticonvulsants; Child, Preschool; Diagnosis, Differential; Drug Eruptions; Humans; Male; Phenobarbi | 2004 |
[Hypersensitivity syndrome caused by phenytoins and phenobarbital].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 1984 |
Eczematous drug reaction from phenobarbitone.
Topics: Drug Eruptions; Female; Humans; Middle Aged; Patch Tests; Phenobarbital | 1984 |
Enhanced differential diagnosis of anticonvulsant hypersensitivity reactions by an integrated Bayesian and biochemical approach.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Carbamazepine; Cell Death; Child; Diagnosis | 1994 |
Erythroderma and marked atypical lymphocytosis mimicking cutaneous T-cell lymphoma probably caused by phenobarbital.
Topics: Dermatitis, Exfoliative; Diagnosis, Differential; Drug Eruptions; Humans; Lymphocytosis; Lymphoma, T | 1993 |
[Stevens-Johnson syndrome and fixed drug eruption].
Topics: Diagnosis, Differential; Drug Eruptions; Humans; Hypnotics and Sedatives; Phenobarbital; Stevens-Joh | 1995 |
Erythema multiforme to phenobarbital: involvement of eosinophils and T cells expressing the skin homing receptor.
Topics: Adult; Anticonvulsants; Drug Eruptions; Eosinophils; Erythema Multiforme; Humans; Male; Phenobarbita | 1997 |
[Successful induction of tolerance in an epilepsy patient with phenobarbital allergy].
Topics: Adult; Anticonvulsants; Desensitization, Immunologic; Dose-Response Relationship, Drug; Drug Adminis | 1998 |
Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital.
Topics: Adult; Drug Eruptions; Eosinophilia; Heart Failure; Humans; Hypnotics and Sedatives; Male; Myocardit | 1998 |
Lamotrigine and phenobarbitone-associated hypersensitivity syndrome: resolution without corticosteroids.
Topics: Aged; Anticonvulsants; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lip D | 1998 |
[The drug hypersensitivity syndrome or DRESS syndrome to phenobarbital].
Topics: Aged; Anticonvulsants; Cholestasis, Intrahepatic; Drug Eruptions; Edema; Eosinophilia; Epilepsy; Fem | 2001 |
Suspected hypersensitivity to phenobarbital in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Diagnosis, Differential; Drug Eruptions; Male; Phenoba | 1999 |
Characterization of drug-specific T cells in phenobarbital-induced eruption.
Topics: Adult; Aged; Antigen Presentation; CD4 Antigens; Cell Movement; Child, Preschool; Clone Cells; Drug | 2002 |
Jaundice and rash associated with the use of phenobarbital and hydrochlorothiazide.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Hydrochlorothiaz | 1976 |
[The lymphocyte transformation test in drug hypersensitivities].
Topics: Anti-Bacterial Agents; Antibody Formation; Cell Migration Inhibition; Diazepam; Drug Eruptions; Huma | 1976 |
Drugs causing fixed eruptions.
Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phen | 1979 |
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption | 1979 |
[Depigmentation of the skin and hair after phenobarbital induced eruption].
Topics: Adult; Drug Eruptions; Hair Diseases; Humans; Hypopigmentation; Male; Microscopy, Electron; Phenobar | 1992 |
A case of tubulo-interstitial nephritis with exfoliative dermatitis and hepatitis due to phenobarbital hypersensitivity.
Topics: Chemical and Drug Induced Liver Injury; Child, Preschool; Dermatitis, Exfoliative; Drug Eruptions; D | 1992 |
Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome.
Topics: Adult; Carbamazepine; Cross Reactions; Drug Eruptions; Facial Dermatoses; Humans; Male; Middle Aged; | 1991 |
Erythema multiforme major in a 2-month-old child with human immunodeficiency virus (HIV) infection.
Topics: Acquired Immunodeficiency Syndrome; Drug Eruptions; Erythema Multiforme; HIV Infections; HIV-1; Huma | 1990 |
Phenobarbital hypersensitivity reaction.
Topics: Child; Drug Eruptions; Drug Hypersensitivity; Female; Fever; Humans; Liver Function Tests; Phenobarb | 1986 |
Generalized drug reaction sparing nevus depigmentosus.
Topics: Drug Eruptions; Humans; Male; Middle Aged; Nevus; Phenobarbital; Skin Neoplasms | 1986 |
Phenobarbital-induced allergic dermatitis.
Topics: Adolescent; Drug Eruptions; Eczema; Epilepsies, Partial; Female; Humans; Phenobarbital | 1987 |
[Fixed bullous erythema after administration of corvalol].
Topics: Chest Pain; Drug Eruptions; Erythema Multiforme; Humans; Male; Middle Aged; Phenobarbital | 1987 |
Hypersensitivity reaction to anticonvulsants following head injury.
Topics: Adolescent; Brain Injuries; Drug Eruptions; Humans; Male; Phenobarbital; Phenytoin | 1987 |
Barbiturate jaundice. Report of a case due to a barbital-containing drug, with positive rechallenge to phenobarbital.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Barbiturates; Chemic | 1969 |
Treatment dermatitis. 2. Dermatitis medicamentosa.
Topics: Chlortetracycline; Drug Eruptions; Gold; Heparin; Humans; Lichen Planus; Lupus Vulgaris; Phenobarbit | 1969 |
[Pathomechanic variants of allergic drug induced skin injuries].
Topics: Allergens; Aminopyrine; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Exanthema; Femal | 1969 |
Unusual phenobarbitone sensitivity.
Topics: Child; Drug Eruptions; Drug Hypersensitivity; Female; Hepatomegaly; Humans; Phenobarbital | 1971 |
Cell mediated hypersensitivity in skin reactions to drugs (except contact dermatitis).
Topics: Allopurinol; Ampicillin; Aspirin; Cell Migration Inhibition; Colistin; Dermatitis, Contact; Drug Eru | 1973 |