phenobarbital has been researched along with Depressive Disorder in 19 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As the result of the detailed analysis of the literature the author recommends lamotrigine, carbamazepine and oxcarbazepine as first choice antiepileptic drug for epileptic patients suffering from depressive disorder, too." | 4.84 | [Effects of antiepileptic drugs on mood of people with epilepsy]. ( Rajna, P, 2007) |
| "The paper describes the case of a depressive syndrome induced in a nine-year-old boy, with complex localised attacks and secondary generalisation, which completely receded on treatment with Convulsofin." | 1.28 | [A barbiturate derivative-induced depressive syndrome in a 9-year-old boy with complex focal seizures and secondary generalization--a case report]. ( Hässler, F, 1989) |
| "The bioavailability of dexamethasone (DEX) has recently been demonstrated to be a critical factor in determining Dexamethasone Suppression Test (DST) status in psychiatric patients." | 1.27 | Dexamethasone bioavailability: implications for DST research. ( Lowy, MT; Meltzer, HY, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Machado, RA | 1 |
| Espinosa, AG | 1 |
| Melendrez, D | 1 |
| González, YR | 1 |
| García, VF | 1 |
| Rodríguez, YQ | 1 |
| MARSH, DO | 1 |
| SCHNIEDEN, H | 1 |
| MARSHALL, J | 1 |
| NORRIS, AS | 1 |
| RYPSON, L | 1 |
| ZIELINSKI, J | 1 |
| PRESTON, DN | 1 |
| ATACK, EA | 1 |
| KAST, EC | 1 |
| Rajna, P | 1 |
| Ostergaard, GZ | 1 |
| Pedersen, SE | 1 |
| Campbell, M | 1 |
| Cueva, JE | 1 |
| Campbell, JJ | 1 |
| McNamara, ME | 1 |
| Schneider, S | 1 |
| Charles, F | 1 |
| Chichmanian, RM | 1 |
| Montoya, ML | 1 |
| Rampal, P | 1 |
| Schneier, HA | 1 |
| Kahn, D | 1 |
| Brent, DA | 2 |
| Crumrine, PK | 2 |
| Varma, R | 1 |
| Brown, RV | 1 |
| Allan, MJ | 1 |
| Hässler, F | 1 |
| Keitner, GI | 1 |
| Fruzzetti, AE | 1 |
| Miller, IW | 1 |
| Norman, WH | 1 |
| Brown, WA | 1 |
| O'Connor, WT | 1 |
| Earley, B | 1 |
| Leonard, BE | 1 |
| Varma, RR | 1 |
| Allan, M | 1 |
| Allman, C | 1 |
| Lowy, MT | 1 |
| Meltzer, HY | 1 |
| Sandman, CA | 1 |
| Barron, JL | 1 |
| Parker, L | 1 |
2 reviews available for phenobarbital and Depressive Disorder
| Article | Year |
|---|---|
[Effects of antiepileptic drugs on mood of people with epilepsy].
Topics: Affect; Anticonvulsants; Antidepressive Agents; Carbamazepine; Depressive Disorder; Epilepsy; Fructo | 2007 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder | 1995 |
17 other studies available for phenobarbital and Depressive Disorder
| Article | Year |
|---|---|
Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Comorbidity; Depressive Disorder; Electroencephalography; | 2011 |
A CONTROLLED CLINICAL TRIAL OF ALPHA METHYL DOPA IN PARKINSONIAN TREMOR.
Topics: Depression; Depressive Disorder; Hypnotics and Sedatives; Methyldopa; Parasympatholytics; Parkinsoni | 1963 |
THE TIRED MOTHER.
Topics: Antidepressive Agents; Counseling; Depression; Depressive Disorder; Diagnosis; Fatigue; Humans; Marr | 1964 |
[DEPRESSION OF LACTATION WITH LUMINAL].
Topics: Breast Feeding; Depression; Depressive Disorder; Female; Humans; Lactation; Phenobarbital; Pregnancy | 1963 |
TEMPORAL LOBE EPILEPSY: A CLINICAL STUDY OF 47 CASES.
Topics: Adolescent; Biomedical Research; Birth Injuries; Depression; Depressive Disorder; Diagnosis, Differe | 1964 |
OBSERVATIONS OF PSYCHOMOTOR BEHAVIOR AS AN INDEX OF PSYCHOPHARMACOLOGIC ACTION.
Topics: Antidepressive Agents; Biomedical Research; Depression; Depressive Disorder; Dextroamphetamine; Drug | 1964 |
Neonatal effects of maternal clomipramine treatment.
Topics: Acidosis, Respiratory; Clomipramine; Cyanosis; Depressive Disorder; Female; Humans; Infant, Newborn; | 1982 |
A case of phenobarbital behavioral toxicity presenting as a menstrually related mood disorder.
Topics: Adult; Depressive Disorder; Diagnosis, Differential; Epilepsy; Female; Humans; Intellectual Disabili | 1993 |
[Acute hepatitis associated with microvesicular steatosis induced by Atrium].
Topics: Acute Disease; Adult; Barbiturates; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; | 1995 |
Selective response to carbamazepine in a case of organic mood disorder.
Topics: Aged; Carbamazepine; Depressive Disorder; Female; Humans; Neurocognitive Disorders; Phenobarbital; P | 1990 |
Phenobarbital treatment and major depressive disorder in children with epilepsy: a naturalistic follow-up.
Topics: Adolescent; Analysis of Variance; Carbamazepine; Child; Depressive Disorder; Epilepsy; Follow-Up Stu | 1990 |
[A barbiturate derivative-induced depressive syndrome in a 9-year-old boy with complex focal seizures and secondary generalization--a case report].
Topics: Anticonvulsants; Child; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Epilepsie | 1989 |
The effect of anticonvulsants on the dexamethasone suppression test.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Dexamethasone; Epileps | 1989 |
Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Biogenic Amines; B | 1985 |
Phenobarbital treatment and major depressive disorder in children with epilepsy.
Topics: Adolescent; Carbamazepine; Child; Depressive Disorder; Epilepsy; Humans; Phenobarbital; Suicide, Att | 1987 |
Dexamethasone bioavailability: implications for DST research.
Topics: Biological Availability; Carbamazepine; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans | 1987 |
Disregulation of hypothalamic-pituitary-adrenal axis in the mentally retarded.
Topics: Adult; Depressive Disorder; Dexamethasone; Hospitalization; Humans; Hydrocortisone; Hypothalamo-Hypo | 1985 |