Page last updated: 2024-11-02

phenobarbital and Dehydration

phenobarbital has been researched along with Dehydration in 12 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Dehydration: The condition that results from excessive loss of water from a living organism.

Research Excerpts

ExcerptRelevanceReference
" Four patients experienced relapse with a decreased dosage of valproate."2.74Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate. ( Amakata, K; Fujii, Y; Hikita, T; Kaga, F; Kaneko, S; Kodama, H; Nakamoto, N; Ogita, K; Yanagawa, Y, 2009)
"When phenobarbital was infused about 2."1.28Kinetics of drug action in disease states. XXXVII. Effects of acute fluid overload and water deprivation on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline in rats. ( Levy, G; Zhi, JG, 1989)
"Most had had a convulsion before admission."1.26Dexamethasone in the treatment of hypernatraemic dehydration. ( Haque, KN, 1981)
"In the next three months, two recurrences of this syndrome were verified and successfully treated in a similar manner."1.25Recurrent hyperosmolar nonketotic episodes in a young diabetic. ( Ginsberg-Fellner, F; Primack, WA, 1975)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patel, C1
Kleinig, P1
Bakker, M1
Tait, P1
Hikita, T1
Kodama, H1
Nakamoto, N1
Kaga, F1
Amakata, K1
Ogita, K1
Kaneko, S1
Fujii, Y1
Yanagawa, Y1
WONG, LC1
HEIMBACH, MD1
TRUSCOTT, DR1
DUNCAN, BD1
Boris, A1
Stevenson, RH1
Haque, KN1
Tallian, KB1
Nahata, MC1
Tsao, CY1
Ginsberg-Fellner, F1
Primack, WA1
Banister, A1
Matin-Siddiqi, SA1
Hatcher, GW1
Zhi, JG1
Levy, G1
Lannek, B1
Hohorst, HJ1
Ziemann, A1
Brock, N1
Shaywitz, BA1

Reviews

2 reviews available for phenobarbital and Dehydration

ArticleYear
Palliative sedation: A safety net for the relief of refractory and intolerable symptoms at the end of life.
    Australian journal of general practice, 2019, Volume: 48, Issue:12

    Topics: Aged; Analgesics; Conscious Sedation; Dehydration; Dyspnea; Humans; Hydromorphone; Hypnotics and Sed

2019
Role of the ketogenic diet in children with intractable seizures.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3

    Topics: Acetazolamide; Anticonvulsants; Avitaminosis; Child; Child, Preschool; Dehydration; Food-Drug Intera

1998

Trials

1 trial available for phenobarbital and Dehydration

ArticleYear
Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Dehydration; Dose-Response Relationship, Drug; Drug Admini

2009

Other Studies

9 other studies available for phenobarbital and Dehydration

ArticleYear
BORIC ACID POISONING: REPORT OF 11 CASES.
    Canadian Medical Association journal, 1964, Apr-25, Volume: 90

    Topics: Acidosis; Anti-Bacterial Agents; Borates; Boric Acids; Color Perception Tests; Dehydration; Diarrhea

1964
The effects of some psychotropic drugs on dehydration induced antidiuretic hormone activity in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 166, Issue:2

    Topics: Animals; Antidepressive Agents; Dehydration; Male; Monoamine Oxidase Inhibitors; Phenobarbital; Rats

1967
Dexamethasone in the treatment of hypernatraemic dehydration.
    Archives of disease in childhood, 1981, Volume: 56, Issue:3

    Topics: Blood Glucose; Calcium; Dehydration; Dexamethasone; Humans; Hypernatremia; Infant; Phenobarbital; Se

1981
Recurrent hyperosmolar nonketotic episodes in a young diabetic.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:2

    Topics: Blood Glucose; Chlorides; Dehydration; Diabetes Mellitus, Type 1; Diabetic Coma; Female; Glucose; Hu

1975
Treatment of hypernatraemic dehydration in infancy.
    Archives of disease in childhood, 1975, Volume: 50, Issue:3

    Topics: Bicarbonates; Body Weight; Dehydration; Gastroenteritis; Humans; Hyperglycemia; Hypernatremia; Hypoc

1975
Kinetics of drug action in disease states. XXXVII. Effects of acute fluid overload and water deprivation on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline in rats.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3

    Topics: Animals; Dehydration; Glucose; Male; Phenobarbital; Rats; Rats, Inbred Lew; Seizures; Theophylline;

1989
Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up.
    Acta veterinaria Scandinavica, 1974, Volume: 15, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dehydration; Dog Diseases; Dogs; Electrocardiograph

1974
4-Ketocyclophosphamide, a metabolite of cyclophosphamide. Formation, chemical and biological properties.
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:8

    Topics: Alkylation; Animals; Chemical Phenomena; Chemistry; Cyanides; Cyclophosphamide; Dehydration; Ketones

1971
Extreme elevations of cerebrospinal fluid protein. Association with hypernatremic dehydration.
    American journal of diseases of children (1960), 1970, Volume: 120, Issue:1

    Topics: Blood Proteins; Blood-Brain Barrier; Central Nervous System Diseases; Cerebrospinal Fluid Proteins;

1970