Page last updated: 2024-11-02

phenobarbital and Deficiency, Vitamin K

phenobarbital has been researched along with Deficiency, Vitamin K in 6 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
" The hypothesis is that the above mentioned chemicals can be responsible for a vitamin K deficiency in the babies resulting in a bleeding analogous with phenobarbital."3.67Dioxins and furans in the mother and possible effects on the fetus and newborn breast-fed baby. ( Koppe, JG, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiménez, R1
Gerken, DK1
Yeary, RA1
Renzulli, P1
Tuchschmid, P1
Eich, G1
Fanconi, S1
Schwöbel, MG1
Koppe, JG1
Matschiner, JT1
Willingham, AK1
Alagille, D1
Odievre, M1
Houllemare, L1
Viterbo, G1
Leroy, D1

Reviews

1 review available for phenobarbital and Deficiency, Vitamin K

ArticleYear
[Advances in neonatology: vitamin K, intracranial hemorrhage, arterial pressure, hemolytic disease].
    Anales espanoles de pediatria, 1984, Oct-15, Volume: 21, Issue:5

    Topics: Antihypertensive Agents; Blood Coagulation Disorders; Cerebral Hemorrhage; Erythroblastosis, Fetal;

1984

Other Studies

5 other studies available for phenobarbital and Deficiency, Vitamin K

ArticleYear
Effect of anticonvulsants on in vitro prothrombin synthesis in adult and fetal rat liver.
    Toxicology and applied pharmacology, 1981, Volume: 61, Issue:3

    Topics: Aging; Animals; Anticonvulsants; Female; In Vitro Techniques; Liver; Male; Phenobarbital; Phenytoin;

1981
Early vitamin K deficiency bleeding after maternal phenobarbital intake: management of massive intracranial haemorrhage by minimal surgical intervention.
    European journal of pediatrics, 1998, Volume: 157, Issue:8

    Topics: Anticonvulsants; Cesarean Section; Epilepsy, Generalized; Female; Hematoma, Subdural; Humans; Infant

1998
Dioxins and furans in the mother and possible effects on the fetus and newborn breast-fed baby.
    Acta paediatrica Scandinavica. Supplement, 1989, Volume: 360

    Topics: Adult; Dioxins; Female; Furans; Hemorrhage; Humans; Infant, Newborn; Milk, Human; Phenobarbital; Pre

1989
Influence of sex hormones on vitamin K deficiency and epoxidation of vitamin K in the rat.
    The Journal of nutrition, 1974, Volume: 104, Issue:6

    Topics: Animals; Carbon Radioisotopes; Castration; DDT; Estradiol; Ethers, Cyclic; Female; Gonadal Steroid H

1974
[Severe neonatal avitaminosis K in 2 infants born of a mother treated with anticonvulsants].
    Archives francaises de pediatrie, 1968, Volume: 25, Issue:1

    Topics: Adult; Epilepsy; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Preg

1968