phenobarbital has been researched along with Deficiency, Vitamin D in 19 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of loss of seizure control due to hypocalcemia resulting from long-term treatment with phenytoin and phenobarbital." | 3.72 | Loss of seizure control due to anticonvulsant-induced hypocalcemia. ( Al-Busairi, WA; Al-Bustan, MA; Al-Mulla, FA; Ali, FE, 2004) |
| " Hypocalcaemia was related to high dosage of anticonvulsant drugs, to multiple drug therapy, and to the use of individual anticonvulsant drugs in the following order, with decreasing order of importance: pheneturide, primidone, phenytoin, phenobarbitone." | 1.25 | Disturbance of calcium metabolism by anticonvulsant drugs. ( Richens, A; Rowe, DJ, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (73.68) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awa, HD | 1 |
| Chelo, D | 1 |
| Kinkela, MN | 1 |
| Ndombo, PO | 1 |
| Akın, L | 1 |
| Kurtoğlu, S | 1 |
| Yıldız, A | 1 |
| Akın, MA | 1 |
| Kendirici, M | 1 |
| Ali, FE | 1 |
| Al-Bustan, MA | 1 |
| Al-Busairi, WA | 1 |
| Al-Mulla, FA | 1 |
| Seymour, HM | 1 |
| Glendenning, P | 1 |
| Fraser, DR | 1 |
| Goraya, JS | 1 |
| Gupta, PN | 1 |
| Gupta, RK | 1 |
| Bahadur, R | 1 |
| Parmar, VR | 1 |
| Gascon-Barré, M | 1 |
| Côte, MG | 1 |
| Brodeur, J | 1 |
| Gascon Barré, M | 1 |
| Cinti, DL | 1 |
| Hosking, DJ | 1 |
| Williams, A | 1 |
| Godwin-Austen, RB | 1 |
| Allison, SP | 1 |
| Wilczek, H | 1 |
| Ston, J | 1 |
| Hrba, J | 1 |
| Pacovský, V | 1 |
| Justová, V | 1 |
| Silver, J | 1 |
| Davies, TJ | 1 |
| Kupersmitt, E | 1 |
| Orme, M | 1 |
| Petrie, A | 1 |
| Vajda, F | 1 |
| Schaefer, K | 2 |
| von Herrath, D | 2 |
| Kraft, D | 2 |
| Reynolds, EH | 1 |
| Koch, HU | 1 |
| Burckhardt, P | 1 |
| Spirer, Z | 1 |
| Weintraub, M | 1 |
| Lerman, P | 1 |
| Shor, S | 1 |
| Boagir, N | 1 |
| Krawitt, EL | 1 |
| Stubbert, PA | 1 |
| Richens, A | 1 |
| Rowe, DJ | 1 |
3 reviews available for phenobarbital and Deficiency, Vitamin D
| Article | Year |
|---|---|
Regulation of the metabolism of vitamin D.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Blood Proteins; Calcium; Carrier Proteins; Chicke | 1980 |
[Vitamin D: influence of anticonvulsant drugs on its metabolism].
Topics: Animals; Anticonvulsants; Dihydroxycholecalciferols; Humans; Hydroxycholecalciferols; Hydroxylation; | 1977 |
Disordered calcium metabolism during anticonvulsant treatment.
Topics: Adolescent; Animals; Anticonvulsants; Biliary Tract; Bone Diseases; Calcium; Child; Cholecalciferol; | 1973 |
16 other studies available for phenobarbital and Deficiency, Vitamin D
| Article | Year |
|---|---|
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Human | 2013 |
Vitamin D deficiency rickets mimicking pseudohypoparathyroidism.
Topics: Anticonvulsants; Calcium; Diagnosis, Differential; Humans; Infant; Male; Phenobarbital; Phosphates; | 2010 |
Loss of seizure control due to anticonvulsant-induced hypocalcemia.
Topics: Adult; Anticonvulsants; Humans; Hypocalcemia; Male; Phenobarbital; Phenytoin; Seizures; Vitamin D De | 2004 |
Fit for a fracture.
Topics: Anticonvulsants; Epilepsy; Ergocalciferols; Female; Femoral Neck Fractures; Follow-Up Studies; Fract | 2005 |
Anticonvulsant induced osteomalacia.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant; Male; Osteomalacia; Ph | 2000 |
Hepatic drug metabolism after phenobarbital and diphenylhydantoin administration in the rat--influence of vitamin D3 status.
Topics: Animals; Calcium; Cholecalciferol; Hexobarbital; Liver; Male; Mixed Function Oxygenases; Pharmaceuti | 1979 |
25-hydroxycholecalciferol: high affinity substrate for hepatic cytochrome P-450.
Topics: Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Dihydrotachysterol; Enzyme Activ | 1977 |
Osteomalacia presenting as chorea.
Topics: Adolescent; Alkaline Phosphatase; Chorea; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; H | 1975 |
[Unusual manifestation of vitamin D metabolism disorder in a patient treated with anticonvulsants (author's transl)].
Topics: Adult; Anticonvulsants; Humans; Hydantoins; Male; Phenobarbital; Vitamin D Deficiency | 1976 |
Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Cholecalciferol; Diet; Enzyme Induction; | 1974 |
Iatrogenic nutritional effects of anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Blood Coagulation Disorders; Bone Diseases; Child; Child, Presch | 1974 |
Influence of diphenylhydantoin and phenobarbital on intestinal calcium transport in the rat.
Topics: Animals; Binding, Competitive; Calcium; Calcium Isotopes; Calcium Metabolism Disorders; Epilepsy; In | 1972 |
[Osteomalacia: new aspects of pathogenesis and treatment].
Topics: Calcium; Humans; Hydantoins; Hyperparathyroidism; Osteomalacia; Phenobarbital; Phosphorus; Rickets; | 1973 |
[Rickets and osteomalacia induced by anticonvulsant drugs].
Topics: Anticonvulsants; Epilepsy; Humans; Hydantoins; Israel; Osteomalacia; Phenobarbital; Rickets; Vitamin | 1974 |
The effect of phenobarbital on intestinal calcium transport.
Topics: Animals; Body Weight; Calcium; Calcium Isotopes; Duodenum; Ileum; Intestinal Absorption; Intestine, | 1972 |
Disturbance of calcium metabolism by anticonvulsant drugs.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Calcium Metabolism Disorders; Enzyme | 1970 |