phenobarbital has been researched along with Deficiency, Riboflavin in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Excerpt | Relevance | Reference |
---|---|---|
"The effects of riboflavin deficiency on electron transport components and drug metabolism activities have been noted only in adult animals after prolonged periods of deficiency." | 1.26 | The effect of certain vitamin deficiencies on hepatic drug metabolism. ( Sato, PH; Zannoni, VG, 1976) |
"The phenobarbital pretreatment induced aniline and acetanilide hydroxylase activity even in riboflavin-deficient animals." | 1.25 | Hepatic drug hydroxylation and lipid peroxidation in riboflavin-deficient rats. ( Galdhar, NR; Patel, JM; Pawar, SS, 1974) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Zannoni, VG | 1 |
Sato, PH | 1 |
Makhija, SJ | 1 |
Galdhar, NR | 3 |
Pawar, SS | 5 |
Campbell, TC | 1 |
Hayes, JR | 1 |
Shargel, L | 1 |
Mazel, P | 1 |
Patel, JM | 3 |
1 review available for phenobarbital and Deficiency, Riboflavin
Article | Year |
---|---|
Role of nutrition in the drug-metabolizing enzyme system.
Topics: Ascorbic Acid Deficiency; Calcium; Carbohydrates; Carcinogens; Catalysis; Chemical and Drug Induced | 1974 |
7 other studies available for phenobarbital and Deficiency, Riboflavin
Article | Year |
---|---|
The effect of certain vitamin deficiencies on hepatic drug metabolism.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Avitaminosis; Cytochrome P-450 Enzyme System; Cyto | 1976 |
Phenobarbital induced variations in hepatic ethyl-morphine n-demethylase and inorganic pyrophosphatase during riboflavin deficiency.
Topics: Animals; Ethylmorphine-N-Demethylase; Liver; Male; Oxidoreductases, N-Demethylating; Phenobarbital; | 1975 |
Effect of dietary riboflavin levels and phenobarbital pretreatment on hepatic drug metabolizing enzymes and lipid peroxidation in young male rats.
Topics: Animals; Lipid Metabolism; Liver; Male; Phenobarbital; Rats; Riboflavin Deficiency | 1975 |
Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat.
Topics: Aminopyrine N-Demethylase; Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 E | 1973 |
Effect of riboflavin deficiency on liver microsomal enzyme system and lipid peroxidation in male rats.
Topics: Animals; Ascorbic Acid; Cytochrome c Group; Cytochrome Reductases; Cytochromes; Lipid Metabolism; Ma | 1973 |
Riboflavin and drug metabolism in adult male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochrome c Group; Cytochr | 1974 |
Hepatic drug hydroxylation and lipid peroxidation in riboflavin-deficient rats.
Topics: Acetanilides; Aniline Compounds; Animals; Ascorbic Acid; Female; Hydroxylation; Kinetics; Lipid Meta | 1974 |