phenobarbital has been researched along with Cushing's Syndrome in 9 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " But enzyme induction can also lead to acute intermittent porphyrias and distrubances of the phosphorus-calcium metabolism." | 3.65 | [Liver metabolism of drugs (author's transl)]. ( Darnis, F, 1976) |
| "The bioavailability of dexamethasone (DEX) has recently been demonstrated to be a critical factor in determining Dexamethasone Suppression Test (DST) status in psychiatric patients." | 1.27 | Dexamethasone bioavailability: implications for DST research. ( Lowy, MT; Meltzer, HY, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Darnis, F | 2 |
| Trubnikov, BM | 1 |
| Yakata, M | 1 |
| Lowy, MT | 1 |
| Meltzer, HY | 1 |
| Werk, EE | 1 |
| Thrasher, K | 1 |
| Choi, Y | 1 |
| Sholiton, LJ | 1 |
| Yamamoto, T | 1 |
| Iwasaki, Y | 1 |
| Adachi, Y | 1 |
| Nakamura, M | 1 |
| Black, M | 1 |
2 reviews available for phenobarbital and Cushing's Syndrome
| Article | Year |
|---|---|
[Enzyme induction in the liver--its mechanism and clinical significance].
Topics: Animals; Cushing Syndrome; DNA; Dogs; Drug Synergism; Enzyme Induction; Enzyme Repression; Glucocort | 1972 |
[6 Beta-hydroxycortisol].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Animals; Chemical Phenomena; Che | 1967 |
7 other studies available for phenobarbital and Cushing's Syndrome
| Article | Year |
|---|---|
[Liver metabolism of drugs (author's transl)].
Topics: Adult; Animals; Anticonvulsants; Biotransformation; Calcium; Child; Cushing Syndrome; Dicumarol; Dru | 1976 |
[Methods of treating the Itsenko-Cushing hypothalamo-hypophyseal syndrome].
Topics: Adolescent; Adult; Belladonna Alkaloids; Cushing Syndrome; Drug Combinations; Electronarcosis; Ergot | 1977 |
[The liver and metabolism of drugs].
Topics: Biotransformation; Cushing Syndrome; Drug Antagonism; Enzyme Induction; Humans; Jaundice; Liver; Phe | 1976 |
[Clinical significance of urinary 6 beta-hydroxycortisol analysis in endocrine tests of the adrenal cortex].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Cushing Syndrome; Female; Humans; Hyd | 1989 |
Dexamethasone bioavailability: implications for DST research.
Topics: Biological Availability; Carbamazepine; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans | 1987 |
Failure of metyrapone to inhibit 11-hydroxylation of 11-deoxycortisol during drug therapy.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Chromatography, Paper; Chrom | 1967 |
Drugs and the liver.
Topics: Bilirubin; Cushing Syndrome; DDT; Enzyme Induction; Ethanol; Female; Humans; Hyperbilirubinemia; Inf | 1970 |