Page last updated: 2024-11-02

phenobarbital and Craniocerebral Injuries

phenobarbital has been researched along with Craniocerebral Injuries in 17 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"Odds for epilepsy were higher among people who had positive family history (O."2.69A case control study and one year follow-up of registered epilepsy cases in a resettlement colony of North India, a developing tropical country. ( Chopra, JS; Kaur, P; Sawhney, IM; Singh, A; Suri, G, 1999)
"Male accounted for 51."1.72Electroencephalographic Findings, Antiepileptic Drugs and Risk Factors of 433 Individuals Referred to a Tertiary Care Hospital in Ethiopia. ( Amare, A; Ayele, BA; Belay, HD; Gebrewold, MA; Gelan, YD; Gugssa, SA; Hagos, T; Kifelew, S; Mengesha, AT; Moges, A; Negash, HA; Oda, DM; Tsehayneh, F; Yifru, YM; Zewde, YZ, 2022)
" In these patients SHS developed during the first 7 months of therapy and regressed after PB discontinuation or, in 2 cases, after dosage reduction."1.31Shoulder-hand syndrome in neurosurgical patients treated with barbiturates. A long term evaluation. ( Bello, L; Ceccarelli, G; Cesana, BM; De Santis, A; Spagnoli, D; Villani, RM, 2000)
"Phenobarbital therapy was promptly effective."1.26Paroxysmal choreoathetosis following head injury. ( Robin, JJ, 1977)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's3 (17.65)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Ayele, BA1
Belay, HD1
Oda, DM1
Gelan, YD1
Negash, HA1
Kifelew, S1
Gebrewold, MA1
Hagos, T1
Zewde, YZ1
Yifru, YM1
Tsehayneh, F1
Amare, A1
Moges, A1
Gugssa, SA1
Mengesha, AT1
Pfenninger, J1
Kaiser, G1
Lütschg, J1
Sutter, M1
Wilberger, JE1
Cantella, D1
Sylvester, CE1
Marchlewski, A1
Manaligod, JM1
Sawhney, IM1
Singh, A1
Kaur, P1
Suri, G1
Chopra, JS1
De Santis, A1
Ceccarelli, G1
Cesana, BM1
Bello, L1
Spagnoli, D1
Villani, RM1
Robin, JJ1
Acs, H1
Kilchevsky, E1
Smith, JL1
Sacks, E1
Hierons, R1
Saunders, M1
Grand, W1
Rapport, RL1
Penry, JK1
Alexander, E2
Popek, K1
Holub, V1
Carroll, BJ1
Adeloye, A1
Familusi, JB1
Alabi, GO1
Latunde Odeku, E1

Reviews

1 review available for phenobarbital and Craniocerebral Injuries

ArticleYear
High-dose barbiturates for intracranial pressure control.
    New horizons (Baltimore, Md.), 1995, Volume: 3, Issue:3

    Topics: Barbiturates; Cerebrovascular Circulation; Craniocerebral Trauma; Dose-Response Relationship, Drug;

1995

Trials

1 trial available for phenobarbital and Craniocerebral Injuries

ArticleYear
A case control study and one year follow-up of registered epilepsy cases in a resettlement colony of North India, a developing tropical country.
    Journal of the neurological sciences, 1999, May-01, Volume: 165, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Child; Craniocerebral Trauma; Developmenta

1999

Other Studies

15 other studies available for phenobarbital and Craniocerebral Injuries

ArticleYear
Electroencephalographic Findings, Antiepileptic Drugs and Risk Factors of 433 Individuals Referred to a Tertiary Care Hospital in Ethiopia.
    Ethiopian journal of health sciences, 2022, Volume: 32, Issue:5

    Topics: Adult; Anticonvulsants; Brain Neoplasms; Craniocerebral Trauma; Electroencephalography; Epilepsy; Et

2022
Treatment and outcome of the severely head injured child.
    Intensive care medicine, 1983, Volume: 9, Issue:1

    Topics: Adolescent; Body Temperature; Child; Child, Preschool; Craniocerebral Trauma; Critical Care; Dexamet

1983
Primidone or phenobarbital use complicating disruptive behavior disorders.
    Clinical pediatrics, 1994, Volume: 33, Issue:4

    Topics: Adolescent; Adolescent Behavior; Craniocerebral Trauma; Dangerous Behavior; Humans; Male; Mental Dis

1994
Shoulder-hand syndrome in neurosurgical patients treated with barbiturates. A long term evaluation.
    Journal of neurosurgical sciences, 2000, Volume: 44, Issue:2

    Topics: Adult; Barbiturates; Craniocerebral Trauma; Female; Follow-Up Studies; Humans; Intracranial Aneurysm

2000
Paroxysmal choreoathetosis following head injury.
    Annals of neurology, 1977, Volume: 2, Issue:5

    Topics: Adult; Athetosis; Chorea; Craniocerebral Trauma; Humans; Male; Phenobarbital

1977
Cranial bruising and intraventricular hemorrhage.
    Pediatrics, 1986, Volume: 78, Issue:5

    Topics: Birth Injuries; Cerebral Hemorrhage; Craniocerebral Trauma; Humans; Infant, Newborn; Phenobarbital

1986
Epilepsy in a community--management and social impact.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Jun-15, Volume: 67, Issue:24

    Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Carbamazepine; Craniocerebral Trauma; Epilepsy;

1985
Impotence in patients with temporal-lobe lesions.
    Lancet (London, England), 1966, Oct-08, Volume: 2, Issue:7467

    Topics: Adult; Craniocerebral Trauma; Electroencephalography; Epilepsy, Temporal Lobe; Erectile Dysfunction;

1966
The significance of post-traumatic status epilepticus in childhood.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:2

    Topics: Age Factors; Cerebral Cortex; Child; Child, Preschool; Consciousness; Craniocerebral Trauma; Electro

1974
A survey of attitudes toward the pharmacological prophylaxis of posttraumatic epilepsy.
    Journal of neurosurgery, 1973, Volume: 38, Issue:2

    Topics: Anticonvulsants; Attitude of Health Personnel; Craniocerebral Trauma; Epilepsy, Post-Traumatic; Huma

1973
Medical management of closed head injuries.
    Clinical neurosurgery, 1972, Volume: 19

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Anti-Bacterial Agents; Blood Transfusion; Cerebral Angi

1972
Surgical management of head injuries in children in the acute phase.
    Clinical neurosurgery, 1972, Volume: 19

    Topics: Adolescent; Age Factors; Cerebral Angiography; Child; Child, Preschool; Craniocerebral Trauma; Femal

1972
[Clinical attempt to prevent post-traumatic epilepsy in children].
    Casopis lekaru ceskych, 1969, Volume: 108, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Craniocerebral Trauma; Electroencephalography; Epilepsy, Post-T

1969
Barbiturate overdosage: presentation with focal neurological signs.
    The Medical journal of Australia, 1969, May-31, Volume: 1, Issue:22

    Topics: Adult; Alcoholism; Amobarbital; Barbiturates; Basilar Artery; Bromides; Cerebral Hemorrhage; Coma; C

1969
Stevens-Johnson syndrome following anticonvulsant therapy in penetrating head injury.
    Ghana medical journal, 1971, Volume: 10, Issue:1

    Topics: Adult; Anticonvulsants; Child; Craniocerebral Trauma; Female; Humans; Male; Phenobarbital; Stevens-J

1971