phenobarbital has been researched along with Coronary Disease in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum low-density lipoprotein cholesterol and high-density lipoprotein cholesterol concentration and the ratio between them, major risk factors of coronary heart disease, and liver size were investigated in 18 subjects who were on enzyme-inducing anticonvulsants, phenytoin alone or in combination with phenobarbital and/or carbamazepine." | 3.67 | Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes. ( Luoma, PV; Pelkonen, RO; Pirttiaho, HI; Sotaniemi, EA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ARECCO, F | 1 |
| SOLARI, E | 1 |
| FRANCO, R | 1 |
| ZUVIRIA, EM | 1 |
| HEIDE, M | 1 |
| MACKENZIE, GJ | 1 |
| PASCUAL, S | 1 |
| Wimmer, H | 1 |
| Spesshardt, K | 1 |
| Luoma, PV | 1 |
| Sotaniemi, EA | 1 |
| Pelkonen, RO | 1 |
| Pirttiaho, HI | 1 |
| Goss, JE | 1 |
| Dickhaus, DW | 1 |
| Fesenko, IP | 1 |
1 trial available for phenobarbital and Coronary Disease
| Article | Year |
|---|---|
Increased bishydroxycoumarin requirements in patients receiving phenobarbital.
Topics: Adult; Aged; Blood Coagulation Tests; Clinical Trials as Topic; Coronary Disease; Dicumarol; Humans; | 1965 |
7 other studies available for phenobarbital and Coronary Disease
| Article | Year |
|---|---|
[Parasympathicolytic effects of a delayed-absorption combination of belladonna and phenylethylbarbituric acid].
Topics: Atropa belladonna; Barbiturates; Cholecystitis; Cholelithiasis; Coronary Disease; Gastroenterology; | 1963 |
[TREATMENT OF THE ANGINAL SYNDROME AND CORONARY INSUFFICIENCY WITH HOSTAGINAN].
Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Humans; Pharmacology; Phenob | 1964 |
[THERAPEUTIC EXPERIENCES WITH MYOCARDON IN PECTANGINOUS DISORDERS].
Topics: Aminophylline; Angina Pectoris; Atropine; Autonomic Nervous System Diseases; Barbiturates; Coronary | 1964 |
PAROXYSMAL VENTRICULAR TACHYCARDIA.
Topics: Coronary Disease; Diagnosis; Digitalis Glycosides; Electrocardiography; Heart Failure; Hydrocortison | 1964 |
[The treatment of heart diseases from various causes with the combination preparation Spasmo-Guttacor].
Topics: Coronary Disease; Heart Failure; Humans; Papaverine; Phenobarbital; Plants, Medicinal; Quinidine | 1966 |
Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes.
Topics: Adult; Carbamazepine; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 Enzyme | 1985 |
[Delipin treatment of patients with arteriosclerotic cardiosclerosis].
Topics: Adult; Ascorbic Acid; Coronary Disease; Female; Humans; Male; Methionine; Middle Aged; Phenobarbital | 1972 |