Page last updated: 2024-11-02

phenobarbital and Coproporphyria, Hereditary

phenobarbital has been researched along with Coproporphyria, Hereditary in 1 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Coproporphyria, Hereditary: An autosomal dominant porphyria that is due to a deficiency of COPROPORPHYRINOGEN OXIDASE in the LIVER, the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, 5-AMINOLEVULINATE and COPROPORPHYRINS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Conway, AJ1
Brown, FC1
Fullinfaw, RO1
Kile, BT1
Jane, SM1
Curtis, DJ1

Other Studies

1 other study available for phenobarbital and Coproporphyria, Hereditary

ArticleYear
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen.
    Disease models & mechanisms, 2017, 08-01, Volume: 10, Issue:8

    Topics: Anemia, Hypochromic; Animals; Base Sequence; Biosynthetic Pathways; Coproporphyria, Hereditary; Copr

2017