phenobarbital has been researched along with Clostridium tetani Infection in 39 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus." | 7.63 | Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951) |
| " The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus." | 3.63 | Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (97.44) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BASU, SK | 1 |
| PAUL, SS | 1 |
| KAUR, P | 1 |
| GUPTA, S | 1 |
| HARRISON, GA | 1 |
| ROSEN, M | 1 |
| GOODALL, P | 1 |
| ABRATE, M | 1 |
| LALLONI, R | 1 |
| WEINBERG, WA | 1 |
| ADAMS, EB | 1 |
| HOLLOWAY, R | 1 |
| THAMBIRAN, AK | 2 |
| BOX, QT | 1 |
| MAURY, H | 1 |
| BRESLAU, RC | 1 |
| HENDRICKSE, RG | 1 |
| SHERMAN, PM | 1 |
| GODMAN, HE | 1 |
| Miśkowiak, B | 1 |
| Bereszyńska, I | 1 |
| Gomez, RC | 1 |
| Huck, S | 1 |
| Gupta, SM | 1 |
| Takkar, VP | 1 |
| Verma, AK | 1 |
| Joseph, A | 1 |
| Pulimood, BM | 1 |
| Cantanna, R | 1 |
| da Rin Betta, V | 1 |
| Gupta, A | 1 |
| Chopra, K | 1 |
| Khalil, A | 1 |
| Khanna, KK | 1 |
| Kandapalanivelu, P | 1 |
| Balakrishnan, S | 1 |
| Puri, BK | 1 |
| Lall, JC | 1 |
| Gupta, HL | 1 |
| Antia-Obong, OE | 1 |
| Ekanem, EE | 1 |
| Udo, JJ | 1 |
| Utsalo, SJ | 1 |
| Golden, BJ | 1 |
| Crudo, DF | 1 |
| Bass, J | 1 |
| Kucher, R | 1 |
| Steinbereithner, K | 1 |
| Tsueda, K | 1 |
| Jean-Francois, J | 1 |
| Richter, RW | 1 |
| Gautier, J | 2 |
| Lamisse, F | 2 |
| Lamagnère, JP | 1 |
| Cochlin, DL | 1 |
| Tremolières, F | 1 |
| Gibert, C | 1 |
| Vachon, F | 1 |
| Pocidalo, JJ | 1 |
| Ganendran, A | 1 |
| Stacher, G | 1 |
| McNiel, JR | 1 |
| Smythe, PM | 1 |
| Kretzschmar, R | 1 |
| Meyer, HJ | 1 |
| Teschendorf, HJ | 1 |
| Zöllner, B | 1 |
| Rügheimer, E | 1 |
| Bedran, D | 1 |
| Martinez Vidal, JC | 1 |
| Plotnicoff, J | 1 |
| Singh, R | 1 |
| Femi-Pearse, D | 1 |
| Retna, CC | 1 |
2 trials available for phenobarbital and Clostridium tetani Infection
| Article | Year |
|---|---|
Therapeutic trial of methocarbamol (Robinax) in tetanus neonatorum.
Topics: Chlorpromazine; Drug Therapy, Combination; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metho | 1975 |
A controlled study of intramuscular meprobamate in neonatal tetanus.
Topics: Chlorpromazine; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Newborn, Diseases; Inject | 1966 |
37 other studies available for phenobarbital and Clostridium tetani Infection
| Article | Year |
|---|---|
Management of tetanus with case report (a study of 114 cases in a district hospital).
Topics: Anti-Allergic Agents; Chlorpromazine; Histamine H1 Antagonists; Hospitals, District; Humans; Muscle | 1963 |
TETANUS IN CHILDREN IN DELHI.
Topics: Anti-Bacterial Agents; Child; Chlorpromazine; Humans; Immunization, Passive; India; Infant; Infant M | 1963 |
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocor | 1964 |
[CONTRIBUTION TO THE USE OF INTRAVENOUS CHLOROPROMAZINE IN TETANUS].
Topics: Adolescent; Blood Transfusion; Chloral Hydrate; Chlorpromazine; Guaifenesin; Humans; Injections, Int | 1963 |
CONTROL OF THE NEUROMUSCULAR AND CONVULSIVE MANIFESTATIONS OF SEVERE SYSTEMIC TETANUS: CASE REPORT WITH A NEW DRUG, VALIUM (DIAZEPAM).
Topics: Amobarbital; Child; Diazepam; Diphenhydramine; Humans; Neurologic Manifestations; Penicillins; Pheno | 1964 |
SOME MODIFICATIONS IN METHOD OF TREATING TETANUS NEONATORUM WITH INTERMITTENT POSITIVE-PRESSURE RESPIRATION.
Topics: Biomedical Research; Chlorpromazine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mus | 1964 |
THE TREATMENT OF TETANUS.
Topics: Adolescent; Child; Chloramphenicol; Humans; Infant; Infant, Newborn; Penicillins; Phenobarbital; Sta | 1964 |
[A CASE OF TETANUS].
Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Apnea; Ascorbic Acid; Calcium; Gluconates; Huma | 1963 |
THORACOABDOMINAL TETANUS. MAKING OF ACUTE ABDOMINAL CRISIS.
Topics: Abdomen; Abdomen, Acute; Abdominal Cavity; Abdominal Wall; Diagnosis, Differential; Humans; Patholog | 1965 |
THERAPEUTIC TRIAL OF DIAZEPAM IN TETANUS.
Topics: Child; Chlorpromazine; Diazepam; Drug Therapy; Humans; Infant; Infant, Newborn; Infant, Newborn, Dis | 1965 |
Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases.
Topics: Mephenesin; Muscle Rigidity; Phenobarbital; Spasm; Tetanus; Tetanus Toxoid; Tracheotomy | 1951 |
[Neonatal tetanus--our clinico-therapeutic observations].
Topics: Animals; Diazepam; Female; Horses; Humans; Infant, Newborn; Intermittent Positive-Pressure Ventilati | 1984 |
Neonatal tetanus.
Topics: Chlorpromazine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbital; Tet | 1980 |
The estimation of the survival rate of tetanus-intoxicated mice. A model for screening anti-tetanus drugs.
Topics: Animals; Chlorpromazine; Diazepam; Drug Evaluation, Preclinical; Halothane; Male; Mice; Phenobarbita | 1979 |
A retrospective study of tetanus neonatorum and comparative assessment of diazepam in its treatment.
Topics: Chlorpromazine; Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Methocar | 1979 |
Use of diazepam in tetanus--a comparative study.
Topics: Adolescent; Adult; Chlorpromazine; Diazepam; Drug Evaluation; Drug Therapy, Combination; Female; Hum | 1978 |
[Tetanus: 10 years of experience].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diazepam; Female; Flunitrazepam; Humans; Infant; I | 1978 |
Tetanus neonatourm.
Topics: Diazepam; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Tetanus | 1977 |
Tetanus in childhood.
Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Tet | 1976 |
Septicaemia among neonates with tetanus.
Topics: Ampicillin; Chlorpromazine; Comorbidity; Female; Gentamicins; Humans; Infant, Newborn; Male; Nigeria | 1992 |
Neonatal tetanus: a case report and review of modern therapy.
Topics: Diazepam; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Pancuronium; Phenobarbital; Te | 1986 |
[Results of tetanus treatment at intensive care units in Vienna].
Topics: Austria; Diazepam; gamma-Globulins; Humans; Intensive Care Units; Muscle Relaxants, Central; Phenoba | 1969 |
Cardiac standstill in tetanus: review of seven consecutive cases.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Arrest; Heroin Dependence; Humans; H | 1973 |
[Treatment of tetanus with diazepam in patients over 60. Apropos of 26 cases].
Topics: Age Factors; Aged; Curare; Diazepam; Female; Humans; Immunization, Passive; Male; Middle Aged; Pheno | 1968 |
Dystonic reactions due to metoclopramide and phenothiazines resembling tetanus.
Topics: Adult; Diagnosis, Differential; Female; Humans; Male; Metoclopramide; Phenobarbital; Phenothiazines; | 1974 |
Effect of curarization on energy and nitrogen balances in acute tetanus treated by prolonged administration of D tubo-curarine.
Topics: Calorimetry; Diazepam; Energy Metabolism; Humans; Muscles; Nitrogen; Phenobarbital; Proteins; Spirom | 1974 |
Intensive therapy in neonatal tetanus.
Topics: Body Temperature; Chloral Hydrate; Chlorpromazine; Diazepam; Electrocardiography; Humans; Hydrogen P | 1974 |
Intrahepatic cholostasis following combined diazepam-barbiturate therapy in patients with tetanus.
Topics: Adult; Aged; Anti-Bacterial Agents; Chlorpromazine; Cholestasis; Diazepam; Drug Combinations; Female | 1973 |
Assisted respiration in the treatment of neonatal tetanus.
Topics: Chlorpromazine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intubation, Intratracheal; Pheno | 1968 |
[Use of dipotassium clorazepate in the treatment of 35 tetanus cases].
Topics: Adult; Aged; Dibenzazepines; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Phenobarbit | 1971 |
Treatment of tetanus neonatorum.
Topics: Humans; Humidity; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intramuscular; Injections, | 1966 |
[Antagonistic action of natural 5,6-hydrogenated Kava pyrones against strychnine poisoning and experimental local tetanus].
Topics: Anesthetics; Animals; Antidotes; Ataxia; Electromyography; Isonicotinic Acids; Male; Mephenesin; Mic | 1969 |
[Treatment principles of tetanus fromte anesthesiological viewpoint].
Topics: Anesthesia; Child; Diazepam; Female; Humans; Phenobarbital; Respiration, Artificial; Succinylcholine | 1969 |
[Treatment of tetanus in the newborn].
Topics: Chlorpromazine; Diazepam; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; | 1970 |
Clinical observations on tetanus.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Child, Preschool; Chlorpromazine; Female; Humans; | 1968 |
Experience with diazepam in tetanus.
Topics: Adolescent; Adult; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Infant, Newborn; Male; | 1966 |
Tetanus--a study of 78 cases.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; Phenoba | 1966 |