phenobarbital has been researched along with Cleft Palate, Isolated in 18 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital treatment antagonized THC-induced reduction of fetal body weight, but did not reduce resorption rate." | 1.26 | Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism. ( Harbison, RD; Lubin, DJ; Mantilla-Plata, B, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nomura, T | 1 |
| Isa, Y | 1 |
| Kurokawa, N | 1 |
| Kanzaki, T | 1 |
| Tanaka, H | 1 |
| Tada, E | 1 |
| Sakamoto, Y | 1 |
| Yuschak, MM | 1 |
| Gautieri, RF | 1 |
| Friis, ML | 1 |
| Harbison, RD | 1 |
| Mantilla-Plata, B | 1 |
| Lubin, DJ | 1 |
| Anderson, RC | 1 |
| Sullivan, FM | 1 |
| McElhatton, PR | 1 |
| Biale, Y | 1 |
| Lewenthal, H | 1 |
| Aderet, NB | 1 |
| Annegers, JF | 2 |
| Elveback, LR | 2 |
| Hauser, WA | 2 |
| Kurland, LT | 2 |
| Kamath, SA | 1 |
| Phadke, V | 1 |
| Anand, AJ | 1 |
| Patel, RB | 1 |
| Deshpande, DV | 1 |
| Lowe, CR | 1 |
| King, CT | 1 |
| Horigan, E | 1 |
| Wilk, AL | 1 |
| Waddell, WJ | 1 |
| Wynnne, WP | 1 |
| Walker, BE | 1 |
| Patterson, A | 1 |
| Meyer, JG | 1 |
| Poswillo, DE | 1 |
| Elshove, J | 1 |
| van Eck, JH | 1 |
18 other studies available for phenobarbital and Cleft Palate, Isolated
| Article | Year |
|---|---|
Enhancement effects of barbital on the teratogenicity of aminopyrine.
Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Barbital; Barbiturates; Cleft Palate; Dose-Respon | 1984 |
Teratogenicity of 13-cis retinoic acid and phenobarbital sodium in CF-1 mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Animals, Newborn; Body Weight; Bone and | 1993 |
Epilepsy among parents of children with facial clefts.
Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Ph | 1979 |
American Academy of Pediatrics Committee on Drugs: anticonvulsants and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec | 1979 |
Alteration of delta 9-tetrahydrocannabinol-induced teratogenicity by stimulation and inhibition of its metabolism.
Topics: Amniotic Fluid; Animals; Body Weight; Cleft Palate; Dronabinol; Drug Interactions; Female; Fetal Dea | 1977 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadio | 1976 |
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.
Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchan | 1975 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord | 1975 |
Epilepsy anticonvulsants and malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec | 1975 |
Epilepsy and craniofacial abnormalities.
Topics: Abnormalities, Drug-Induced; Adult; Cleft Lip; Cleft Palate; Epilepsy, Tonic-Clonic; Female; Humans; | 1991 |
Congenital malformations among infants born to epileptic women.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; F | 1973 |
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Dise | 1972 |
The effect of pretreatment with phenobarbital on the teratogenic action of chorcyclizine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Dealkylation; Drug Antagonism; Embryo Implantati | 1971 |
Induction of cleft palate in mice by tranquilizers and barbiturates.
Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Cleft Palate; Diazepam; Female; Hydroxyzine | 1974 |
Do anticonvulsants have a teratogenic effect?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital | 1974 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe | 1973 |
Orofacial malformations.
Topics: Animals; Antimetabolites; Cell Differentiation; Cleft Lip; Cleft Palate; Dermoid Cyst; Eye Neoplasms | 1974 |
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Fema | 1971 |