Page last updated: 2024-11-02

phenobarbital and Cleft Lip

phenobarbital has been researched along with Cleft Lip in 11 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Cleft Lip: Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (90.91)	18.7374
1990's	1 (9.09)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Friis, ML	1
Anderson, RC	1
Biale, Y	1
Lewenthal, H	1
Aderet, NB	1
Annegers, JF	2
Elveback, LR	2
Hauser, WA	2
Kurland, LT	2
Kamath, SA	1
Phadke, V	1
Anand, AJ	1
Patel, RB	1
Deshpande, DV	1
Lowe, CR	1
Meyer, JG	1
Poswillo, DE	1
Elshove, J	1
van Eck, JH	1

Other Studies

11 other studies available for phenobarbital and Cleft Lip

Article	Year
Epilepsy among parents of children with facial clefts. Epilepsia, 1979, Volume: 20, Issue:1 Topics: Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Humans; Male; Parents; Phenobarbital; Ph	1979
American Academy of Pediatrics Committee on Drugs: anticonvulsants and pregnancy. Pediatrics, 1979, Volume: 63, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec	1979
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy. The Journal of pediatrics, 1976, Volume: 89, Issue:2 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadio	1976
Congenital malformations due to anticonvulsive drugs. Obstetrics and gynecology, 1975, Volume: 45, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord	1975
Epilepsy anticonvulsants and malformations. Birth defects original article series, 1975, Volume: 11, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec	1975
Epilepsy and craniofacial abnormalities. The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:2 Topics: Abnormalities, Drug-Induced; Adult; Cleft Lip; Cleft Palate; Epilepsy, Tonic-Clonic; Female; Humans;	1991
Congenital malformations among infants born to epileptic women. Lancet (London, England), 1973, Jan-06, Volume: 1, Issue:7793 Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Congenital Abnormalities; England; Epilepsy; F	1973
Do anticonvulsants have a teratogenic effect? Archives of neurology, 1974, Volume: 31, Issue:6 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child, Preschool; Cleft Lip; Cleft Palate; Congenital	1974
The teratological effects of anticonvulsants and the effects on pregnancy and birth. European neurology, 1973, Volume: 10, Issue:3 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohe	1973
Orofacial malformations. Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:5 Topics: Animals; Antimetabolites; Cell Differentiation; Cleft Lip; Cleft Palate; Dermoid Cyst; Eye Neoplasms	1974
[Congenital abnormalities, cleft lip and cleft palate in particular, in children of epileptic mothers]. Nederlands tijdschrift voor geneeskunde, 1971, Aug-14, Volume: 115, Issue:33 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cleft Lip; Cleft Palate; Epilepsy; Fema	1971