Page last updated: 2024-11-02

phenobarbital and Cirrhosis, Liver

phenobarbital has been researched along with Cirrhosis, Liver in 53 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
" Phenobarbital at plasma concentrations achieved by usual therapeutical dosage schedules of the drug does not interfere with the protein binding of phenprocoumon as could be shown by equilibrium dialysis."5.26[Elimination kinetics of phenprocoumon (Marcumar) in liver cirrhosis and after premedication with phenobarbital]. ( Glogner, P; Heni, N; Lehnhardt, G, 1976)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
"Serum squalene levels did not change in patients with acute hepatitis, chronic active hepatitis and liver cirrhosis, but were significantly reduced in patients with intra- and extrahepatic cholestasis."3.66Serum squalene levels in hepatobiliary diseases. ( Hirayama, C; Ikawa, S; Yamanishi, Y, 1978)
"Salicylamide glucuronide (SAMG) in 0-6 and 6-12 hours-urine specimens was determined after oral administration of salicylamide in 7 normal volunteers (NV), in 51 cases of various liver diseases and hyperbilirubinemias, and in 19 cases after drug administration, to predict the in vivo drug metabolism in man and its change by drugs."3.65Salycylamide glucuronide formation in liver disease and its change by drugs. ( Adachi, Y; Wakisaka, G; Yamamoto, T, 1975)
"Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease."1.51New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease. ( Bosch, J; Boyer-Diaz, Z; Gracia-Sancho, J; Lozano, JJ; Maeso-Díaz, R; Ortega-Ribera, M; Peralta, C, 2019)
"Progressive liver fibrosis leads to cirrhosis and end-stage liver disease."1.46Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation. ( Berardis, S; El Taghdouini, A; El-Kehdy, H; Evraerts, J; Henriet, P; Lombard, C; Najimi, M; Rosseels, V; Sokal, EM; van Grunsven, L, 2017)
"Melatonin is a powerful physiologic scavenger of hydroxyl radicals."1.36Melatonin ameliorates liver fibrosis induced by bile-duct ligation in rats. ( Akin, H; Aydogan, F; Ramadan, SS; Tahan, G; Tahan, V; Tarcin, O; Uzun, H; Yapicier, O; Zengin, K, 2010)
"Throughout different stages of liver fibrosis, leptin immunoreactivity was localized in activated hepatic stellate cells only, whereas immunoreactivity for the receptor was mainly seen on hepatocytes."1.32Expression of leptin and leptin receptor during the development of liver fibrosis and cirrhosis. ( Bornstein, SR; Fölsch, UR; Kloehn, S; Mönig, H; Otte, C; Otte, JM; Strodthoff, D, 2004)
" Phenobarbital at plasma concentrations achieved by usual therapeutical dosage schedules of the drug does not interfere with the protein binding of phenprocoumon as could be shown by equilibrium dialysis."1.26[Elimination kinetics of phenprocoumon (Marcumar) in liver cirrhosis and after premedication with phenobarbital]. ( Glogner, P; Heni, N; Lehnhardt, G, 1976)
"Antipyrine has been used as a model drug to investigate the effects of liver disease on drug metabolism in man."1.25Determinants of serum antipyrine half-lives in patients with liver disease. ( Branch, RA; Herbert, CM; Read, AE, 1973)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199040 (75.47)18.7374
1990's3 (5.66)18.2507
2000's4 (7.55)29.6817
2010's5 (9.43)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Maeso-Díaz, R1
Boyer-Diaz, Z1
Lozano, JJ1
Ortega-Ribera, M1
Peralta, C1
Bosch, J1
Gracia-Sancho, J1
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G1
Sassaroli, S1
Borlimi, R1
Aucoin, M1
Cooley, K1
Saunders, PR1
Carè, J1
Anheyer, D1
Medina, DN1
Cardozo, V1
Remy, D1
Hannan, N1
Garber, A1
Velayos, M1
Muñoz-Serrano, AJ1
Estefanía-Fernández, K1
Sarmiento Caldas, MC1
Moratilla Lapeña, L1
López-Santamaría, M1
López-Gutiérrez, JC1
Li, J1
Zhang, J1
Shen, S1
Zhang, B2
Yu, WW1
Toyoda, H1
Huang, DQ1
Le, MH1
Nguyen, MH1
Huang, R1
Zhu, L1
Wang, J6
Xue, L1
Liu, L2
Yan, X2
Huang, S1
Li, Y6
Xu, T1
Li, C2
Ji, F1
Ming, F1
Zhao, Y2
Cheng, J1
Wang, Y3
Zhao, H1
Hong, S1
Chen, K2
Zhao, XA1
Zou, L1
Sang, D1
Shao, H1
Guan, X1
Chen, X2
Chen, Y4
Wei, J1
Zhu, C1
Wu, C1
Moore, HB1
Barrett, CD1
Moore, EE1
Jhunjhunwala, R1
McIntyre, RC1
Moore, PK1
Hajizadeh, N1
Talmor, DS1
Sauaia, A1
Yaffe, MB1
Liu, C3
Lin, Y1
Dong, Y1
Wu, Y1
Bao, Y1
Yan, H2
Ma, J1
Fernández-Cuadros, ME1
Albaladejo-Florín, MJ1
Álava-Rabasa, S1
Usandizaga-Elio, I1
Martinez-Quintanilla Jimenez, D1
Peña-Lora, D1
Neira-Borrajo, I1
López-Muñoz, MJ1
Rodríguez-de-Cía, J1
Pérez-Moro, OS1
Abdallah, M1
Alsaleh, H1
Baradwan, A1
Alfawares, R1
Alobaid, A1
Rasheed, A1
Soliman, I1
Wendel Garcia, PD1
Fumeaux, T1
Guerci, P1
Heuberger, DM1
Montomoli, J2
Roche-Campo, F1
Schuepbach, RA1
Hilty, MP1
Poloni, TE1
Carlos, AF1
Cairati, M1
Cutaia, C1
Medici, V1
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Hornbuckle, WE1
Tennant, BC1
Aagenaes, O1
Stutts, JT1
Washington, K1
Barnard, JA1
Mücke, I1
Richter, S1
Menger, MD1
Vollmar, B1
Sabra, R1
Shuman, S1
Adachi, Y1
Wakisaka, G1
Yamamoto, T1
Alvin, J1
McHorse, T1
Hoyumpa, A1
Bush, MT1
Schenker, S2
Hoyumpa, AM1
Wilkinson, GR2
Stiehl, A2
Yamanishi, Y1
Ikawa, S1
Hirayama, C1
Loginov, AS1
Heni, N2
Lehnhardt, G1
Glogner, P2
Escartin Marín, P2
Rossi, I2
García Plaza, A1
Díaz Gil, JJ1
Gosalves, M1
Mazzacca, G1
Bianco, AR1
Budillon, G1
Perillo, N1
Williams, CN1
Jorens, PG1
Michielsen, PP1
Pelckmans, PA1
Fevery, J1
Desmet, VJ1
Geubel, AP1
Rahier, J1
Van Maercke, YM1
Morimoto, T1
Jikkoh, A1
Yokoo, N1
Taki, Y1
Tanaka, J1
Kamiyama, Y1
Ozawa, K1
Tobe, T1
Szende, B1
Lapis, K1
Timár, J1
Schaff, Z1
Simon, K1
Jeney, A1
Divald, A1
Paku, S1
Timár, F1
Varin, F1
Huet, PM1
Horne, CH2
Thompson, WD1
Busuttil, A2
MacSween, RN2
Haschen, RJ1
Watanabe, A1
Thompson, RP1
Stathers, GM1
Pilcher, CW1
McLean, AE1
Porta, EA1
Koch, OR1
Hartroft, WS1
Hepner, GW1
Vesell, ES1
Lenhardt, G1
Tsironis, A1
Papacharalampous, NX1
Tchertkoff, V1
Nayak, SV1
Kamath, C1
Salomon, MI1
Fromke, VL1
Miller, D1
Alston, WC1
Branch, RA1
Herbert, CM1
Read, AE1
Bode, JC1
Bode, C1
Zelder, O1
Middeler, A1
Caroli, J1
Nusinovici, V1
Amar, AB1
Lévy, VG1
Kurata, D1
Del Rio, A1
Noya, M1
De Oya, JC1
Khaliq, SU1
Kay, JM1
Heath, D1
Vorne, M1
Rubin, E1
Lieber, CS1

Reviews

7 reviews available for phenobarbital and Cirrhosis, Liver

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Hereditary cholestasis with lymphoedema (Aagenaes syndrome, cholestasis-lymphoedema syndrome). New cases and follow-up from infancy to adult age.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Cholestasis; Consanguinity; Female; Follow-Up Studies; G

1998
The effect of parenchymal liver disease on the disposition and elimination of sedatives and analgesics.
    The Medical clinics of North America, 1975, Volume: 59, Issue:4

    Topics: Analgesics; Anti-Anxiety Agents; Barbiturates; Diazepam; Half-Life; Hepatitis; Humans; Hypnotics and

1975
Disturbances of bile acid metabolism in cholestasis.
    Clinics in gastroenterology, 1977, Volume: 6, Issue:1

    Topics: Bile Acids and Salts; Bile Ducts; Cholestasis; Cholestyramine Resin; Deoxycholic Acid; Disease Model

1977
[Progress in diagnostic enzymology].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Aug-15, Volume: 28, Issue:16

    Topics: Alcoholism; Aminopeptidases; Amylases; Aspartate Aminotransferases; Cholinesterases; Creatine Kinase

1973
Recent advances in molecular pathology: a review of the effects of alcohol on the liver.
    Experimental and molecular pathology, 1970, Volume: 12, Issue:1

    Topics: Acute Disease; Alcoholic Intoxication; Alcoholism; Animals; Butyrates; Chemical and Drug Induced Liv

1970
Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid.
    Medicine, 1972, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Hemolytic, Congenital; Bilirubin; Fe

1972

Trials

1 trial available for phenobarbital and Cirrhosis, Liver

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022

Other Studies

46 other studies available for phenobarbital and Cirrhosis, Liver

ArticleYear
New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease.
    Cells, 2019, 09-10, Volume: 8, Issue:9

    Topics: Animals; Carbon Tetrachloride; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fatty Li

2019
Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation.
    Stem cell research & therapy, 2017, 06-05, Volume: 8, Issue:1

    Topics: Animals; Biomarkers; Carbon Tetrachloride; Cell Proliferation; Coculture Techniques; Culture Media,

2017
Chemoprevention by lipid-soluble tea polyphenols in diethylnitrosamine/phenobarbital-induced hepatic pre-cancerous lesions.
    Anticancer research, 2014, Volume: 34, Issue:2

    Topics: Animals; Cell Growth Processes; Diethylnitrosamine; DNA Damage; Immunohistochemistry; Lipids; Liver;

2014
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
    Journal of forensic sciences, 2014, Volume: 59, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A

2014
Melatonin ameliorates liver fibrosis induced by bile-duct ligation in rats.
    Canadian journal of surgery. Journal canadien de chirurgie, 2010, Volume: 53, Issue:5

    Topics: Acridines; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransfe

2010
A fatal case of toxic epidermal necrolysis associated with liver cirrhosis.
    The Journal of emergency medicine, 2003, Volume: 24, Issue:1

    Topics: Child; Disease Progression; Dose-Response Relationship, Drug; Emergency Service, Hospital; Fatal Out

2003
DIPHENYLHYDANTOIN AND PHENOBARBITAL TOXICITY. THE ROLE OF LIVER DISEASE.
    Archives of neurology, 1964, Volume: 11

    Topics: Ataxia; Barbiturates; Blood Chemical Analysis; Chromatography; Drug Tolerance; Hepatitis; Hepatitis

1964
Expression of leptin and leptin receptor during the development of liver fibrosis and cirrhosis.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2004, Volume: 112, Issue:1

    Topics: Animals; Blotting, Western; Carbon Tetrachloride; Gene Expression Regulation; Immunohistochemistry;

2004
Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:4

    Topics: Adult; Aged; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; He

1980
Different effects of carbon tetrachloride toxicity and cirrhosis on substrate binding to rat hepatic microsomal cytochrome P-450.
    Biochemical pharmacology, 1984, Feb-15, Volume: 33, Issue:4

    Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Ethylmorphine; Liver Cirrhosis; Male;

1984
Assessment of the cytochrome P-448 dependent liver enzyme system by a caffeine breath test.
    European journal of clinical pharmacology, 1981, Volume: 21, Issue:1

    Topics: Adult; Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Cytochrome P-450 CYP1A

1981
Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs.
    Journal of the American Veterinary Medical Association, 1982, Aug-15, Volume: 181, Issue:4

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Female; Liver; Liver Cirrhosis; Male; Microscopy, Elec

1982
Cholestatic jaundice with skin desquamation in a 12-year-old girl.
    The Journal of pediatrics, 1999, Volume: 134, Issue:5

    Topics: Atropine; Child; Cholestasis; Cryptogenic Organizing Pneumonia; Drug Combinations; Fatal Outcome; Fe

1999
Significance of hepatic arterial responsiveness for adequate tissue oxygenation upon portal vein occlusion in cirrhotic livers.
    International journal of colorectal disease, 2000, Volume: 15, Issue:5-6

    Topics: Animals; Blood Flow Velocity; Carbon Tetrachloride; Erythrocytes; Female; Liver; Liver Cirrhosis; Ma

2000
Influence of phenobarbital on changes in Na(+) handling, hemodynamics and liver function due to partial portal vein ligation in rats.
    European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3

    Topics: Animals; Blood Pressure; Excitatory Amino Acid Antagonists; Glomerular Filtration Rate; Hemodynamics

2001
Salycylamide glucuronide formation in liver disease and its change by drugs.
    Gastroenterologia Japonica, 1975, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Barbiturates; Bilirubin; Child; Female; Gilbert Disease; Glucuronates; Hepa

1975
The effect of liver disease in man on the disposition of phenobarbital.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bile; Bilirubin; Carbon Radioisotopes; Chr

1975
Serum squalene levels in hepatobiliary diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Aug-15, Volume: 88, Issue:1

    Topics: Acute Disease; Adult; Azathioprine; Biliary Tract Diseases; Cholestasis; Cholesterol; Cholestyramine

1978
[Treatment of chronic diseases of the liver].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:1

    Topics: Adrenal Cortex Hormones; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Phenob

1977
[Elimination kinetics of phenprocoumon (Marcumar) in liver cirrhosis and after premedication with phenobarbital].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:4

    Topics: Adult; Aged; Coumarins; Humans; Kinetics; Liver Cirrhosis; Male; Middle Aged; Phenobarbital; Phenpro

1976
[A preliminary study of the behavior of hepatic microsomal enzymes in cirrhotic and healthy patients].
    Revista clinica espanola, 1975, Mar-31, Volume: 136, Issue:6

    Topics: Cytochrome P-450 Enzyme System; Gluconates; Humans; Liver; Liver Cirrhosis; Methods; Microsomes, Liv

1975
[Enzyme induction in cirrhotic patients].
    Revista espanola de las enfermedades del aparato digestivo, 1975, Volume: 45, Issue:6

    Topics: Enzyme Induction; Glucuronates; Humans; Liver; Liver Cirrhosis; Phenobarbital; Stimulation, Chemical

1975
The source of ascitic fluid in experimental cirrhosis in the rat.
    Pathologia et microbiologia, 1975, Volume: 42, Issue:1

    Topics: Animals; Ascitic Fluid; Carbon Tetrachloride; Fluoresceins; Fluoroscopy; Liver Cirrhosis; Male; Peri

1975
Bile-acid metabolism and the liver.
    Clinical biochemistry, 1976, Volume: 9, Issue:3

    Topics: Barbiturates; Bile Acids and Salts; Cholestasis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Phe

1976
Vitamin A abuse: development of cirrhosis despite cessation of vitamin A. A six-year clinical and histopathologic follow-up.
    Liver, 1992, Volume: 12, Issue:6

    Topics: Adult; Biopsy; Colchicine; Follow-Up Studies; Humans; Hypertension, Portal; Hypervitaminosis A; Live

1992
Changes in coenzyme Q level in mitochondria of cirrhotic rat liver.
    Life sciences, 1985, Apr-22, Volume: 36, Issue:16

    Topics: Animals; Carbon Tetrachloride; Electron Transport Complex IV; Liver Cirrhosis; Mitochondria, Liver;

1985
Glycosaminoglycan containing fat-storing cells in hepatic fibrogenesis.
    Acta morphologica Hungarica, 1988, Volume: 36, Issue:3-4

    Topics: Animals; Carbon Tetrachloride; Glycosaminoglycans; Lipid Metabolism; Lipids; Liver; Liver Cirrhosis;

1988
Hepatic microcirculation in the perfused cirrhotic rat liver.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:5

    Topics: Animals; Extracellular Space; Lidocaine; Liver; Liver Cirrhosis; Male; Microcirculation; Microsphere

1985
Long-term effects of carbon tetrachloride and sodium phenobarbitone administration on rat serum proteins.
    British journal of experimental pathology, 1973, Volume: 54, Issue:2

    Topics: Alpha-Globulins; Animals; Blood Proteins; Body Weight; Carbon Tetrachloride; gamma-Globulins; Immuno

1973
Effect of chronic administration of centrally acting compounds on chloramphenicol metabolism in schizophrenic patients.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Adult; Antipsychotic Agents; Chloramphenicol; Chronic Disease; Female; Glucuronates; Half-Life; Huma

1974
Treatment of unconjugated jaundice with dicophane.
    Lancet (London, England), 1969, Jul-05, Volume: 2, Issue:7610

    Topics: Adolescent; Animals; Bilirubin; Cytochromes; DDT; Enzyme Induction; Glucuronates; Humans; Hyperbilir

1969
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
    The New England journal of medicine, 1974, Dec-26, Volume: 291, Issue:26

    Topics: Administration, Oral; Adult; Aged; Alcoholism; Aminopyrine; Breath Tests; Carbon Dioxide; Carbon Rad

1974
[Pharmacokinetics of phenprocoumon (Marcumar) in patients with liver cirrhosis and following induction treatment with phenobarbital].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Benzyl Compounds; Coumarins; Drug Synergism; Enzyme Induction; Humans; Liver Cirrhosis; Phenobarbita

1974
[The induction of liver cirrhosis in rats by simultaneous administration of carbon tetrachloride and phenobarbitone (author's transl)].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1973, Volume: 117, Issue:2

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drug Synergism; Liver Cirrhosis; Male

1973
Hyperosmolar nonketotic diabetic coma: vascular complications.
    Journal of the American Geriatrics Society, 1974, Volume: 22, Issue:10

    Topics: Adult; Aged; Brain Edema; Diabetic Coma; Diabetic Nephropathies; Esophageal and Gastric Varices; Fem

1974
[Treatment of cholestasis with phenobarbital].
    Zeitschrift fur Gastroenterologie, 1972, Volume: 10, Issue:8

    Topics: Bile Ducts, Intrahepatic; Cholestasis; Humans; Liver Cirrhosis; Liver Diseases; Phenobarbital

1972
Effect of the production of experimental cirrhosis in rats on serum aminotransferase levels.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1972, Volume: 17, Issue:10

    Topics: Alanine; Animals; Aspartic Acid; Carbon Tetrachloride; Drug Synergism; Kinetics; Liver Cirrhosis; Ph

1972
Determinants of serum antipyrine half-lives in patients with liver disease.
    Gut, 1973, Volume: 14, Issue:7

    Topics: Adult; Alkaline Phosphatase; Antipyrine; Aspartate Aminotransferases; Bilirubin; Half-Life; Hepatiti

1973
[Influence of protocaval anastomosis on cytoplasmatic, mitochondrial and microsomal enzyme activities in normal and cirrhotic rat liver].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Animals; Liver; Liver Cirrhosis; Male; Phenobarbital; Portacaval Shunt, Surgical; Rats; Time Factors

1973
[Acholangic cholestatic hepatitis evolving towards xanthomatosis and cirrhosis].
    Annales de medecine interne, 1973, Volume: 124, Issue:11

    Topics: Bile Ducts; Bilirubin; Biopsy; Blood Proteins; Cholestasis; Female; Glutethimide; Hepatitis; Humans;

1973
Erythrocyte uptake and plasma binding of diphenylhydantoin.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:2

    Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylatio

1974
[Therapeutic reduction of the indirect serum bilirubin level through enzyme induction using phenobarbital (Luminal)].
    Der Internist, 1968, Apr-25, Volume: 9, Issue:3

    Topics: Bilirubin; Child; Enzyme Induction; Humans; Hyperbilirubinemia; Liver; Liver Cirrhosis; Phenobarbita

1968
[Phenobarbital treatment of indirect hyperbilirubinemia states in various hepatic diseases].
    Revista clinica espanola, 1972, Mar-15, Volume: 124, Issue:5

    Topics: Administration, Oral; Hepatitis; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Liver C

1972
Porta-pulmonary venous anastomoses in experimental cirrhosis of the liver in rats.
    The Journal of pathology, 1972, Volume: 107, Issue:3

    Topics: Animals; Arteries; Barium Sulfate; Carbon Tetrachloride; Coronary Vessels; Esophagus; Hypoxia; Liver

1972
Effect of partial liver resection and phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride induced liver damage.
    Acta pharmacologica et toxicologica, 1971, Volume: 30, Issue:5

    Topics: Animals; Benzoates; Carbon Tetrachloride Poisoning; Cytochromes; Enzyme Induction; Hepatectomy; Hexo

1971
Alcohol, other drugs, and the liver.
    Annals of internal medicine, 1968, Volume: 69, Issue:5

    Topics: Alcoholism; Animals; Central Nervous System; Chemical and Drug Induced Liver Injury; Ethanol; Humans

1968