phenobarbital has been researched along with Cirrhoses, Experimental Liver in 62 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We investigated to what extent antipyrine clearance and metabolite formation are impaired in two models of liver cirrhosis in the rat, namely micronodular cirrhosis induced by chronic exposure to phenobarbital/CCl4 and biliary cirrhosis induced by bile duct ligation." | 3.68 | Metabolism of antipyrine in vivo in two rat models of liver cirrhosis. Its relationship to intrinsic clearance in vitro and microsomal membrane lipid composition. ( Buters, JT; Reichen, J; Zysset, T, 1993) |
| " We induced cirrhosis with hypertrophy in rats by simultaneous treatment with CCl4 and phenobarbital (PB) and devised a hierarchy of structure applicable to the sampling and morphometric analysis of untreated and PB-treated control livers and of cirrhotic livers." | 3.66 | A morphometric analysis of the hypertrophy of experimental liver cirrhosis. ( Buschmann, RJ; Ryoo, JW, 1983) |
| "Throughout different stages of liver fibrosis, leptin immunoreactivity was localized in activated hepatic stellate cells only, whereas immunoreactivity for the receptor was mainly seen on hepatocytes." | 1.32 | Expression of leptin and leptin receptor during the development of liver fibrosis and cirrhosis. ( Bornstein, SR; Fölsch, UR; Kloehn, S; Mönig, H; Otte, C; Otte, JM; Strodthoff, D, 2004) |
| "In summary, osteopenia characterized by loss of bone mass and preserved bone composition was found in rats with advanced cirrhosis induced by CCl4 and phenobarbital in drinking water." | 1.31 | Effects of IGF-I treatment on osteopenia in rats with advanced liver cirrhosis. ( Castilla-Cortázar, I; Cemborain, A; Delgado, G; Díaz-Sánchez, M; García, M; Muguerza, B; Picardi, A, 2000) |
| "As phenobarbital also has a hepatotrophic effect, its role in liver regeneration following partial hepatectomy (HTX) is not elucidated." | 1.30 | Phenobarbital in comparison with carbon tetrachloride and phenobarbital-induced cirrhosis in rat liver regeneration. ( Hashimoto, M; Kothary, PC; Raper, SE, 1999) |
| "Nuclear localization was found in biliary cirrhosis only." | 1.29 | Differential effect of micronodular and biliary cirrhosis on epidermal growth factor receptor expression in the rat. ( Marti, U; Oguey, D; Reichen, J, 1994) |
| " The chronic administration of the NO synthesis inhibitor NG-nitro-L-arginine-methyl-ester (L-NAME) (10 mg/kg/day for 7 days) induced a marked reduction in aortic cGMP concentration in cirrhotic rats with ascites to similar values obtained in L-NAME-treated control rats (86 +/- 14 vs." | 1.29 | Increased aortic cyclic guanosine monophosphate concentration in experimental cirrhosis in rats: evidence for a role of nitric oxide in the pathogenesis of arterial vasodilation in cirrhosis. ( Ginès, P; Martin, PY; McMurtry, I; Morris, K; Niederberger, M; Schrier, RW; Tsai, P; Weigert, A, 1995) |
| "05), area under the curve and terminal half-life were significantly increased (p < 0." | 1.29 | Indocyanine green pharmacokinetics in rats with progressive carbon tetrachloride-induced hepatocellular insufficiency. ( Delrat, P; Dupin, S; Houin, G; Le Quellec, A; Voigt, JJ, 1994) |
| "A common model for producing experimental liver cirrhosis is the administration of CCl4 to phenobarbital (PhB)-stimulated rats." | 1.28 | Liver cirrhosis in rats: regeneration and assessment of the role of phenobarbital. ( Ahren, B; Alumets, J; Bengmark, S; Foss, A; Jeppsson, B; Rozga, J, 1991) |
| "Phenobarbital-treated rats had greater initial aminopyrine rate constant of elimination, but we saw a similar fall in aminopyrine rate constant of elimination of about 40% within 1 wk of bile duct excision to a value still above baseline aminopyrine rate constant of elimination of untreated controls." | 1.28 | Phenobarbital influences the development of sodium retention in liver disease induced by bile duct ligation in the rat. ( Branch, RA; Wensing, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (38.71) | 18.7374 |
| 1990's | 29 (46.77) | 18.2507 |
| 2000's | 7 (11.29) | 29.6817 |
| 2010's | 2 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishikawa, T | 1 |
| Bellance, N | 1 |
| Damm, A | 1 |
| Bing, H | 1 |
| Zhu, Z | 1 |
| Handa, K | 1 |
| Yovchev, MI | 1 |
| Sehgal, V | 1 |
| Moss, TJ | 1 |
| Oertel, M | 1 |
| Ram, PT | 1 |
| Pipinos, II | 1 |
| Soto-Gutierrez, A | 1 |
| Fox, IJ | 3 |
| Nagrath, D | 1 |
| Chen, YH | 1 |
| Du, BQ | 1 |
| Zheng, ZJ | 1 |
| Xiang, GM | 1 |
| Liu, XB | 1 |
| Mai, G | 1 |
| Otte, C | 1 |
| Otte, JM | 1 |
| Strodthoff, D | 1 |
| Bornstein, SR | 1 |
| Fölsch, UR | 2 |
| Mönig, H | 1 |
| Kloehn, S | 1 |
| Trivedi, P | 1 |
| Mowat, AP | 1 |
| Ryoo, JW | 2 |
| Buschmann, RJ | 2 |
| Proctor, E | 2 |
| Chatamra, K | 2 |
| Linas, SL | 1 |
| Anderson, RJ | 1 |
| Guggenheim, SJ | 1 |
| Robertson, GL | 1 |
| Berl, T | 1 |
| Ugazio, G | 1 |
| Bosia, S | 1 |
| Cornaglia, E | 1 |
| Oguey, D | 1 |
| Reichen, J | 5 |
| Marti, U | 1 |
| Niederberger, M | 1 |
| Ginès, P | 1 |
| Tsai, P | 1 |
| Martin, PY | 1 |
| Morris, K | 1 |
| Weigert, A | 1 |
| McMurtry, I | 1 |
| Schrier, RW | 1 |
| Wensing, G | 2 |
| Sabra, R | 1 |
| Branch, RA | 2 |
| Zalatnai, A | 4 |
| Lapis, K | 4 |
| Aisen, AM | 1 |
| Doi, K | 1 |
| Swanson, SD | 1 |
| Dupin, S | 1 |
| Delrat, P | 1 |
| Le Quellec, A | 1 |
| Voigt, JJ | 1 |
| Houin, G | 1 |
| Buters, JT | 2 |
| Zysset, T | 2 |
| Atuchá, NM | 1 |
| Quesada, T | 1 |
| Garcia-Estañ, J | 1 |
| Wada, S | 1 |
| Kato, T | 1 |
| Mutai, M | 1 |
| Ozaki, K | 1 |
| Yamaguchi, S | 1 |
| Kim, DJ | 1 |
| Baba-Toriyama, H | 1 |
| Asamoto, M | 1 |
| Ito, N | 1 |
| Tsuda, H | 1 |
| Ralevic, V | 1 |
| Mathie, RT | 1 |
| Moore, KP | 1 |
| Burnstock, G | 1 |
| Masuda, Y | 1 |
| Oguma, T | 1 |
| Kaneko, H | 1 |
| Hashimoto, M | 1 |
| Kothary, PC | 1 |
| Raper, SE | 1 |
| Zimmermann, A | 2 |
| Zhao, D | 1 |
| Dufour, JF | 1 |
| Lüthi, M | 1 |
| Forestier, M | 1 |
| Magnino, F | 1 |
| Siegel, EG | 1 |
| Seidenstücker, A | 1 |
| Gallwitz, B | 1 |
| Schmitz, F | 1 |
| Reinecke-Lüthge, A | 1 |
| Klöppel, G | 1 |
| Schmidt, WE | 1 |
| Kovalovich, K | 1 |
| DeAngelis, RA | 1 |
| Li, W | 1 |
| Furth, EE | 1 |
| Ciliberto, G | 1 |
| Taub, R | 1 |
| Kobayashi, N | 2 |
| Ito, M | 2 |
| Nakamura, J | 2 |
| Cai, J | 2 |
| Gao, C | 1 |
| Hammel, JM | 2 |
| Cemborain, A | 1 |
| Castilla-Cortázar, I | 1 |
| García, M | 1 |
| Muguerza, B | 1 |
| Delgado, G | 1 |
| Díaz-Sánchez, M | 1 |
| Picardi, A | 1 |
| Brandão, CG | 1 |
| Ferreira, HH | 1 |
| Piovesana, H | 1 |
| Polimeno, NC | 1 |
| Ferraz, JG | 1 |
| de Nucci, G | 1 |
| Pedrazzoli, J | 1 |
| Cao, C | 1 |
| McPhie, JL | 1 |
| Short, LT | 1 |
| Baich, A | 1 |
| Chen, PC | 1 |
| Nopanitaya, W | 1 |
| Grisham, JW | 1 |
| Carson, JL | 1 |
| Dotson, MM | 1 |
| Lopez-Novoa, JM | 1 |
| Rengel, MA | 1 |
| Kovalszky, I | 1 |
| Szeberenyi, S | 1 |
| Vincze, I | 1 |
| Jeney, A | 1 |
| Maruyama, H | 1 |
| Amanuma, T | 1 |
| Takashima, Y | 1 |
| Yoshiji, H | 1 |
| Nakae, D | 1 |
| Tsutsumi, M | 1 |
| Tsujiuchi, T | 1 |
| Denda, A | 1 |
| Konishi, Y | 1 |
| Lasierra, J | 1 |
| Barrao, F | 1 |
| Ceña, G | 1 |
| Aza, MJ | 1 |
| Morandeira, MJ | 1 |
| Barrao, ME | 1 |
| González-Gallego, J | 1 |
| Dagenais, M | 1 |
| Giroux, L | 1 |
| Belgiorno, J | 1 |
| Huet, PM | 2 |
| Ingleton, PM | 1 |
| Rodgers, GR | 1 |
| Faulkner, M | 1 |
| Parsons, MA | 1 |
| Sojcic, Z | 1 |
| Roos, FJ | 1 |
| Dubé, C | 1 |
| Vallières, S | 2 |
| Ethier, C | 1 |
| Benbrahim, N | 1 |
| Tremblay, C | 1 |
| Gascon-Barré, M | 2 |
| Rozga, J | 1 |
| Foss, A | 1 |
| Alumets, J | 1 |
| Ahren, B | 1 |
| Jeppsson, B | 1 |
| Bengmark, S | 1 |
| Fischer-Nielsen, A | 1 |
| Poulsen, HE | 1 |
| Hansen, BA | 1 |
| Hage, E | 1 |
| Keiding, S | 1 |
| Sárosi, I | 1 |
| Rot, A | 1 |
| Lapsis, K | 1 |
| Nadkarni, GD | 1 |
| Shimpi, HH | 1 |
| Noronha, OP | 1 |
| Wu, ZQ | 1 |
| Piché, D | 1 |
| López, C | 1 |
| Jiménez, W | 1 |
| Arroyo, V | 1 |
| La Villa, G | 1 |
| Gaya, J | 1 |
| Clària, J | 1 |
| Rivera, F | 1 |
| Rodés, J | 1 |
| d'Arville, CN | 1 |
| Le, M | 1 |
| Kloppel, TM | 1 |
| Simon, FR | 1 |
| Stenbäck, F | 1 |
| Saarni, HU | 1 |
| Rautio, A | 1 |
| Stengård, J | 1 |
| Sotaniemi, EA | 1 |
| Qazi, FM | 1 |
| Alam, SM | 1 |
| Egger, B | 1 |
| Ohara, N | 1 |
| Zeltner, TB | 1 |
| Alwmark, A | 1 |
| Santos, A | 1 |
| Mamlok, V | 1 |
| Greeley, GH | 1 |
| Thompson, JC | 1 |
| Goeting, NL | 1 |
| Fleming, JS | 1 |
| Gallagher, P | 1 |
| Walmsely, BH | 1 |
| Karran, SJ | 1 |
| Horne, CH | 1 |
| Scott, CA | 1 |
| Busuttil, A | 1 |
| Macsween, RN | 1 |
| Serebro, LH | 1 |
| Kew, MC | 1 |
| Kilroe-Smith, TA | 1 |
| Khaliq, SU | 1 |
| Kay, JM | 1 |
| Heath, D | 1 |
| Vorne, M | 1 |
| Marshall, WJ | 2 |
| McLean, AE | 3 |
| McLean, EK | 2 |
| Sutton, PM | 2 |
62 other studies available for phenobarbital and Cirrhoses, Experimental Liver
| Article | Year |
|---|---|
A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Anticonvulsants; Carbon Tetrachloride; Chemical and Dr | 2014 |
Effect of recombinant human growth hormone and interferon gamma on hepatic collagen synthesis and proliferation of hepatic stellate cells in cirrhotic rats.
Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Collagen Type I; Collagen Type I | 2012 |
Expression of leptin and leptin receptor during the development of liver fibrosis and cirrhosis.
Topics: Animals; Blotting, Western; Carbon Tetrachloride; Gene Expression Regulation; Immunohistochemistry; | 2004 |
Carbon tetrachloride-induced hepatic fibrosis and cirrhosis in the developing rat: an experimental model of cirrhosis in childhood.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachlori | 1983 |
A morphometric analysis of the hypertrophy of experimental liver cirrhosis.
Topics: Animals; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Connective Tissue; Hepatomegaly; Hypertroph | 1983 |
High yield micronodular cirrhosis in the rat.
Topics: Animals; Ascites; Body Weight; Carbon Tetrachloride; Dose-Response Relationship, Drug; Liver; Liver | 1982 |
Phenobarbitone-induced enlargement of the liver in the rat: its relationship to carbon tetrachloride-induced cirrhosis.
Topics: Animals; Body Weight; Carbon Tetrachloride; Dose-Response Relationship, Drug; Hepatomegaly; Liver; L | 1981 |
Role of vasopressin in impaired water excretion in conscious rats with experimental cirrhosis.
Topics: Animals; Arginine Vasopressin; Blood Volume; Body Water; Carbon Tetrachloride; Diabetes Insipidus; K | 1981 |
Experimental model of cirrhosis in rabbits exposed to carbon tetrachloride by inhalation.
Topics: Administration, Inhalation; Animals; Body Weight; Carbon Tetrachloride Poisoning; Hexobarbital; Live | 1995 |
Differential effect of micronodular and biliary cirrhosis on epidermal growth factor receptor expression in the rat.
Topics: Animals; Blotting, Northern; Blotting, Western; Carbon Tetrachloride; ErbB Receptors; Liver; Liver C | 1994 |
Increased aortic cyclic guanosine monophosphate concentration in experimental cirrhosis in rats: evidence for a role of nitric oxide in the pathogenesis of arterial vasodilation in cirrhosis.
Topics: Analysis of Variance; Animals; Aorta; Arginine; Blood Pressure; Cyclic GMP; Heart Rate; Liver Cirrho | 1995 |
Relationship between oxidative hepatic metabolism, urinary sodium excretion and sympathetic nerve activity in experimental cirrhosis in the rat.
Topics: Aminopyrine; Animals; Blood Pressure; Breath Tests; Carbon Tetrachloride; Glomerular Filtration Rate | 1995 |
Simultaneous induction of liver cirrhosis and hepatocellular carcinomas in F-344 rats: establishment of a short hepatocarcinogenesis model.
Topics: Animals; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Hepatectomy; | 1994 |
Detection of liver fibrosis with magnetic cross-relaxation.
Topics: Animals; Body Water; Carbon Tetrachloride; Hydroxyproline; Image Enhancement; Liver; Liver Cirrhosis | 1994 |
Decreased hepatocarcinogenic effect of diethylnitrosamine in experimentally induced liver cirrhosis in rat: delay or inhibition?
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1994 |
Indocyanine green pharmacokinetics in rats with progressive carbon tetrachloride-induced hepatocellular insufficiency.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Half-Life; Indocyanine Green; Liver; Liver Cir | 1994 |
Metabolism of antipyrine in vivo in two rat models of liver cirrhosis. Its relationship to intrinsic clearance in vitro and microsomal membrane lipid composition.
Topics: Animals; Antipyrine; Bile Acids and Salts; Breath Tests; Carbon Tetrachloride; Lipids; Liver Cirrhos | 1993 |
Reduced renal papillary plasma flow in non-ascitic cirrhotic rats.
Topics: Animals; Body Fluids; Carbon Tetrachloride; Diuresis; Hemodynamics; Kidney Medulla; Liver Cirrhosis, | 1993 |
Modifying influence of swine-serum-induced liver fibrosis on development of preneoplastic lesions in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Blood; Chemical and Drug Induced Liver Injury; Cocarcinogenesis; Deo | 1996 |
Vasoconstrictor responsiveness of the rat mesenteric arterial bed in cirrhosis.
Topics: Adenosine Triphosphate; Animals; Arginine; Disease Models, Animal; Electric Stimulation; Enzyme Inhi | 1996 |
Intrahepatic flow disturbance as detected by in vivo acridine orange staining in endothelin-1-treated and cirrhotic rats.
Topics: Acridine Orange; Animals; Carbon Tetrachloride; Endothelin-1; Femoral Vein; Liver; Liver Circulation | 1998 |
Phenobarbital in comparison with carbon tetrachloride and phenobarbital-induced cirrhosis in rat liver regeneration.
Topics: Animals; Body Weight; Carbon Tetrachloride; Cell Division; DNA; Hepatectomy; Kinetics; Liver; Liver | 1999 |
Myofibroblasts in the cirrhotic rat liver reflect hepatic remodeling and correlate with fibrosis and sinusoidal capillarization.
Topics: Actins; Animals; Bile Ducts, Intrahepatic; Biomarkers; Blood Vessels; Capillaries; Carbon Tetrachlor | 1999 |
Expression of inositol 1,4,5-trisphosphate receptor isoforms in rat cirrhosis.
Topics: Animals; Bile Ducts; Calcium Channels; Carbon Tetrachloride; Immunohistochemistry; Inositol 1,4,5-Tr | 1999 |
Insulin secretion defects in liver cirrhosis can be reversed by glucagon-like peptide-1.
Topics: Analysis of Variance; Animals; Carbon Tetrachloride; Culture Techniques; Dose-Response Relationship, | 2000 |
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice.
Topics: Actins; Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; DNA-B | 2000 |
Hepatocyte transplantation in rats with decompensated cirrhosis.
Topics: Animals; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Transplantation; Graft Survival; Li | 2000 |
Effects of IGF-I treatment on osteopenia in rats with advanced liver cirrhosis.
Topics: Animals; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Carbon Tetrachloride; Densitometry; | 2000 |
Development of an experimental model of liver cirrhosis in rabbits.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Ani | 2000 |
The role of hepatocyte transplantation to treat chronic liver failure.
Topics: Ammonia; Animals; Bilirubin; Carbon Tetrachloride; Cell Transplantation; Chronic Disease; Hepatocyte | 2000 |
Hepatic prolyl hydroxylase activity in experimental cirrhosis.
Topics: Carbon Tetrachloride Poisoning; Coenzymes; Collagen; Hydroxyproline; Liver; Liver Cirrhosis, Experim | 1975 |
Cirrhosis and the synthesis of proline and glycine in rat liver.
Topics: Animals; Carbon Tetrachloride; Collagen; Drug Interactions; Glycine; Liver; Liver Cirrhosis, Experim | 1979 |
Surface features of cirrhotic liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Endothelium; Liver; Liver Cirrhosis, Experimental; Male; Mi | 1976 |
A micropuncture study of salt and water retention in chronic experimental cirrhosis.
Topics: Animals; Carbon Tetrachloride; Diuresis; Glomerular Filtration Rate; Inulin; Kidney; Liver Cirrhosis | 1977 |
Modification of DENA-induced hepatocarcinogenesis by CCl4 cirrhosis. Comparison of the marker enzyme patterns.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Drug Administrati | 1992 |
Possible enhancing effect of the immunosuppressive agent, 6-mercaptopurine(6-MP) on focal lesion development in cirrhotic liver induced by carbon tetrachloride but not furfural in F344 rats.
Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Drug Synergism; Fu | 1992 |
Changes of the fibrinolytic system in liver dysfunction: role of portal hypertension.
Topics: Amino Acid Sequence; Animals; Carbon Tetrachloride Poisoning; Fibrinolysis; Hemodynamics; Hypertensi | 1992 |
The effect of alcohol-induced hepatomegaly on portal hypertension in cirrhotic rats.
Topics: Animals; Blood Pressure; Carbon Tetrachloride; Collagen; Ethanol; Hemodynamics; Hepatomegaly; Hypert | 1992 |
The pituitary in cirrhosis: ultrastructure, growth hormone, and prolactin concentrations.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Golgi Apparatus; Growth Hormone; Immunohistochemistry; | 1992 |
Abnormal lipid composition of microsomes from cirrhotic rat liver--does it contribute to decreased microsomal function?
Topics: Animals; Bile Ducts; Carbon Tetrachloride; Cholesterol; Endoplasmic Reticulum; Fatty Acids; Fluoresc | 1992 |
In micronodular cirrhosis, hepatocytes retain a normal C-25 hydroxylation capacity toward vitamin D3: a study using the rat carbon tetrachloride-induced cirrhotic model.
Topics: Animals; Calcifediol; Carbon Tetrachloride; Cholecalciferol; Cytochrome P-450 Enzyme System; Hydroxy | 1991 |
Liver cirrhosis in rats: regeneration and assessment of the role of phenobarbital.
Topics: Animals; Carbon Tetrachloride; Hepatectomy; Liver; Liver Cirrhosis, Experimental; Liver Regeneration | 1991 |
CCl4 cirrhosis in rats: irreversible histological changes and differentiated functional impairment.
Topics: Animals; Antipyrine; Carbon Tetrachloride; Galactose; Liver; Liver Cirrhosis, Experimental; Male; Ph | 1991 |
Inhibitory and promoting effects of carbon tetrachloride-induced liver cirrhosis on the diethylnitrosamine hepatocarcinogenesis in rats.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Diethylnitrosamine; Liver; Liver Cirr | 1991 |
Biokinetics of 99mTc-labelled liver-imaging agents in an animal model of liver cirrhosis.
Topics: Animals; Carbon Tetrachloride; Disease Models, Animal; Liver; Liver Cirrhosis, Experimental; Male; O | 1991 |
Unimpaired induction of drug-metabolizing enzymes in hepatocytes isolated from rats with micronodular cirrhosis.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Biotransform | 1991 |
Phenobarbital influences the development of sodium retention in liver disease induced by bile duct ligation in the rat.
Topics: Aminopyrine; Animals; Bile Ducts; Breath Tests; Creatinine; Ligation; Liver Cirrhosis, Experimental; | 1990 |
Role of altered systemic hemodynamics in the blunted renal response to atrial natriuretic peptide in rats with cirrhosis and ascites.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Hemodynamics; Hypotension; Infus | 1989 |
Alterations in the functional expression of receptors on cirrhotic rat hepatocytes.
Topics: Animals; Asialoglycoprotein Receptor; Carbon Tetrachloride Poisoning; Epidermal Growth Factor; ErbB | 1989 |
Reversibility of rat liver cirrhosis by medroxyprogesterone acetate.
Topics: Animals; Carbon Tetrachloride Poisoning; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; | 1989 |
Hepatic structural correlates of liver fibrosis: a morphometric analysis.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Female; Liver; Liver Cirrhosis, Experimental; Mitochond | 1989 |
Potentiating effects of phenobarbitone on the induction of cirrhosis in rats by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Drug Synergism; Female; Liver; Liver Cirrhosis, Experimental; Necrosi | 1988 |
Determinants of hepatic function in liver cirrhosis in the rat. Multivariate analysis.
Topics: Animals; Carbon Tetrachloride; Galactose; Hemodynamics; Liver; Liver Cirrhosis, Experimental; Liver | 1988 |
Insulin and glucagon production in experimental cirrhosis.
Topics: Animals; Carbon Tetrachloride; Glucagon; In Vitro Techniques; Insulin; Liver Cirrhosis, Experimental | 1987 |
Alterations in liver blood flow and reticuloendothelial function in progressive cirrhosis in the rat.
Topics: Animals; Carbon Tetrachloride Poisoning; Liver; Liver Circulation; Liver Cirrhosis, Experimental; Ma | 1986 |
Effect of the production of experimental cirrhosis in rats on serum protein levels.
Topics: Alpha-Globulins; Animals; Blood Proteins; Carbon Tetrachloride Poisoning; Chemical and Drug Induced | 1973 |
Hepatic zinc concentrations in experimental cirrhosis induced with carbon tetrachloride and phenobarbitone.
Topics: Animals; Carbon Tetrachloride; Liver; Liver Cirrhosis, Experimental; Male; Phenobarbital; Rats; Spec | 1974 |
Porta-pulmonary venous anastomoses in experimental cirrhosis of the liver in rats.
Topics: Animals; Arteries; Barium Sulfate; Carbon Tetrachloride; Coronary Vessels; Esophagus; Hypoxia; Liver | 1972 |
Effect of phenobarbital on the restoration of impaired drug metabolism in carbon tetrachloride-induced liver damage.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Clinical Enzyme Tests; Cytochromes; Enzyme Act | 1971 |
The effect of cirrhosis of the liver on microsomal detoxications and cytochrome P-450.
Topics: Aminopyrine; Animals; Carbon Tetrachloride Poisoning; Cytochromes; Liver; Liver Cirrhosis, Experimen | 1969 |
Instant cirrhosis. An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone.
Topics: Animals; Ascites; Carbon Tetrachloride; Gases; Hypertension, Portal; Liver Cirrhosis, Experimental; | 1969 |
A rapid method for producing cirrhosis of the liver in rats and its effect on microsomal enzyme activity.
Topics: Animals; Carbon Tetrachloride; Liver Cirrhosis, Experimental; Methods; Microsomes, Liver; Phenobarbi | 1970 |