Page last updated: 2024-11-02

phenobarbital and Chronic Kidney Disease-Mineral and Bone Disorder

phenobarbital has been researched along with Chronic Kidney Disease-Mineral and Bone Disorder in 2 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Chronic Kidney Disease-Mineral and Bone Disorder: Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.

Research Excerpts

ExcerptRelevanceReference
"Three children with azotaemic renal osteodystrophy were treated with 1,25-dihydroxycholecalciferol (1,25(OH)2D3)."1.261,25-dihydroxycholecalciferol in renal osteodystrophy. Epiphysiolysis--anticonvulsant therapy. ( Dellagrammatikas, H; Ellis, HA; Norman, AW; Pierides, AM; Scott, JE, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DUNDAS, JB1
Pierides, AM1
Ellis, HA1
Dellagrammatikas, H1
Scott, JE1
Norman, AW1

Other Studies

2 other studies available for phenobarbital and Chronic Kidney Disease-Mineral and Bone Disorder

ArticleYear
LOWE'S SYNDROME.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Chi

1964
1,25-dihydroxycholecalciferol in renal osteodystrophy. Epiphysiolysis--anticonvulsant therapy.
    Archives of disease in childhood, 1977, Volume: 52, Issue:6

    Topics: Adolescent; Bone and Bones; Child, Preschool; Chronic Kidney Disease-Mineral and Bone Disorder; Dihy

1977