phenobarbital has been researched along with Child Mental Disorders in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital (PB) has been traditionally used as the first-line treatment for neonatal seizures." | 5.30 | Short-Term Neurodevelopmental Outcome in Term Neonates Treated with Phenobarbital versus Levetiracetam: A Single-Center Experience. ( Barbagallo, M; Corsello, G; Falsaperla, R; Mauceri, L; Pavone, P; Pisani, F; Ruggieri, M; Vitaliti, G, 2019) |
| "Seizures are common following perinatal asphyxia and may exacerbate secondary neuronal injury." | 2.53 | Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia. ( Berg, M; Soll, R; Young, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chin, EM | 1 |
| Cohen, JS | 1 |
| Harris, J | 1 |
| Falsaperla, R | 1 |
| Mauceri, L | 1 |
| Pavone, P | 1 |
| Barbagallo, M | 1 |
| Vitaliti, G | 1 |
| Ruggieri, M | 1 |
| Pisani, F | 1 |
| Corsello, G | 1 |
| Young, L | 1 |
| Berg, M | 1 |
| Soll, R | 1 |
1 review available for phenobarbital and Child Mental Disorders
| Article | Year |
|---|---|
Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia.
Topics: Anticonvulsants; Asphyxia Neonatorum; Barbiturates; Humans; Infant; Infant, Newborn; Infant, Prematu | 2016 |
1 trial available for phenobarbital and Child Mental Disorders
| Article | Year |
|---|---|
Short-Term Neurodevelopmental Outcome in Term Neonates Treated with Phenobarbital versus Levetiracetam: A Single-Center Experience.
Topics: Anticonvulsants; Female; Humans; Infant, Newborn; Italy; Levetiracetam; Male; Neurodevelopmental Dis | 2019 |
1 other study available for phenobarbital and Child Mental Disorders
| Article | Year |
|---|---|
Vigabatrin as a Targeted Treatment of GABA
Topics: Animals; Anticonvulsants; Chromosomes, Human, Pair 9; Drug Substitution; Electroencephalography; Epi | 2019 |