Page last updated: 2024-11-02

phenobarbital and Child Behavior Disorders

phenobarbital has been researched along with Child Behavior Disorders in 22 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Child Behavior Disorders: Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.

Research Excerpts

ExcerptRelevanceReference
"To compare the behavioural side effects associated with two commonly used antiepilepsy drugs-phenobarbital and carbamazepine-in children in Bangladesh."9.12Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. ( Banu, SH; Ferdousi, S; Jahan, M; Khan, NZ; Koli, UK; Neville, B, 2007)
"To compare the behavioural side effects associated with two commonly used antiepilepsy drugs-phenobarbital and carbamazepine-in children in Bangladesh."5.12Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. ( Banu, SH; Ferdousi, S; Jahan, M; Khan, NZ; Koli, UK; Neville, B, 2007)
"Phenobarbital has been shown to offer effective prophylaxis against childhood febrile convulsions."1.26Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood. ( Lee, K; Melchior, JC, 1981)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's3 (13.64)18.2507
2000's2 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GROSS, MD1
WILSON, WC1
KNOEPFLI, R1
Banu, SH1
Jahan, M1
Koli, UK1
Ferdousi, S1
Khan, NZ1
Neville, B1
Pregelj, S1
Barkauskas, A1
Michaux, L1
Duche, D1
Koupernik, C1
Lelord, G1
Rolland, M1
Wallace, SJ1
Lee, K1
Melchior, JC1
Bacon, CJ1
Cranage, JD1
Hierons, AM1
Rawlins, MD1
Webb, JK1
Campbell, M1
Cueva, JE1
Domizio, S1
Verrotti, A1
Ramenghi, LA1
Sabatino, G1
Morgese, G1
Pal, DK1
Das, T1
Chaudhury, G1
Johnson, AL1
Neville, BG1
Beebe, DS1
Tran, P1
Bragg, M1
Stillman, A1
Truwitt, C1
Belani, KG1
Camfield, CS1
Chaplin, S1
Doyle, AB1
Shapiro, SH1
Cummings, C1
Camfield, PR1
Schain, RJ1
Wolf, SM1
Forsythe, A1
Gairdner, D1
Groh, CH1
Rosenmayr, FW1
Holdsworth, L1
Whitmore, K1
Gregoriades, AD1
Frommer, EA1
Linder, CW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00381537]92 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenobarbital and Child Behavior Disorders

ArticleYear
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder

1995

Trials

5 trials available for phenobarbital and Child Behavior Disorders

ArticleYear
Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial.
    BMJ (Clinical research ed.), 2007, Jun-09, Volume: 334, Issue:7605

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Doubl

2007
Behavioural effects of phenobarbitone and phenytoin in small children.
    Archives of disease in childhood, 1981, Volume: 56, Issue:11

    Topics: Child Behavior Disorders; Female; Hospitalization; Humans; Infant; Male; Phenobarbital; Phenytoin; S

1981
Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India.
    Lancet (London, England), 1998, Jan-03, Volume: 351, Issue:9095

    Topics: Adolescent; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Developing Countries

1998
Side effects of phenobarbital in toddlers; behavioral and cognitive aspects.
    The Journal of pediatrics, 1979, Volume: 95, Issue:3

    Topics: Child Behavior Disorders; Child, Preschool; Clinical Trials as Topic; Cognition Disorders; Dose-Resp

1979
Treatment of childhood depression with antidepressant drugs.
    British medical journal, 1967, Mar-25, Volume: 1, Issue:5542

    Topics: Adolescent; Child; Child Behavior Disorders; Child Psychiatry; Child, Hospitalized; Chlordiazepoxide

1967

Other Studies

16 other studies available for phenobarbital and Child Behavior Disorders

ArticleYear
BEHAVIOR DISORDERS OF CHILDREN WITH CEREBRAL DYSRHYTHMIAS; SUCCESSFUL TREATMENT OF SUBCONVULSIVE DYSRHYTHMIA WITH ANTICONVULSANTS.
    Archives of general psychiatry, 1964, Volume: 11

    Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Child; Child Behavior Disorders; Conduct

1964
[THE NERVOUS CHILD].
    Therapeutische Umschau. Revue therapeutique, 1964, Volume: 21

    Topics: Child; Child Behavior Disorders; Chlorprothixene; Humans; Infant; Phenobarbital

1964
Thioridazine in the treatment of mentally retarded children. (A four-year retroactive evaluation).
    Canadian Psychiatric Association journal, 1967, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Evaluat

1967
[Results contributed by electroencephalographic conditioning to sound and light to the study of the mechanism of action of psychotrophic drugs].
    Annales medico-psychologiques, 1967, Volume: 125, Issue:3

    Topics: Adolescent; Adult; Child; Child Behavior Disorders; Chlordiazepoxide; Chlorpromazine; Conditioning,

1967
Febrile convulsions: their significance for later intellectual development and behaviour.
    Journal of child psychology and psychiatry, and allied disciplines, 1984, Volume: 25, Issue:1

    Topics: Child; Child Behavior Disorders; Child Development; Child, Preschool; Female; Follow-Up Studies; Hum

1984
Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood.
    European journal of pediatrics, 1981, Volume: 137, Issue:2

    Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Seizures, F

1981
Anti-epileptic therapy and behaviour disturbances in children.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1993, Volume: 9, Issue:5

    Topics: Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Chi

1993
Trained nurses can provide safe and effective sedation for MRI in pediatric patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Administration, Rectal; Adolescent; Age Factors; Anesthesia, General; Anesthesiology; Anesthetics, I

2000
Problems with the use of conventional anticonvulsant drugs in mentally retarded individuals.
    Brain & development, 1979, Volume: 1, Issue:2

    Topics: Adolescent; Child; Child Behavior Disorders; Child, Preschool; Cognition; Epilepsy; Humans; Intellec

1979
Behavior disturbance, phenobarbital, and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Barbiturates; Child Behavior Disorders; Humans; Hyperkinesis; Mephobarbital; Phenobarbital; Recurren

1978
Letter: Failure of phenobarbitone to prevent febrile convulsions.
    British medical journal, 1976, Apr-03, Volume: 1, Issue:6013

    Topics: Child; Child Behavior Disorders; Humans; Phenobarbital; Seizures

1976
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
    Pediatrics, 1985, Volume: 76, Issue:4

    Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cogni

1985
[Isolated petit mal status epilepticus. A new epilepsy syndrome characterised by paroxysmal behavioural disturbances (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Mar-01, Volume: 99, Issue:9

    Topics: Benzodiazepinones; Child; Child Behavior Disorders; Cognition Disorders; Diagnosis, Differential; Di

1974
A study of children with epilepsy attending ordinary schools. I: their seizure patterns, progress and behaviour in school.
    Developmental medicine and child neurology, 1974, Volume: 16, Issue:6

    Topics: Adolescent; Aggression; Attention; Child; Child Behavior Disorders; Child, Preschool; Colitis, Ulcer

1974
A medical and social survey of 231 children with seizures.
    Epilepsia, 1972, Volume: 13, Issue:1

    Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalog

1972
Breath-holding spells in children. Studies of frequency, severity, management.
    Clinical pediatrics, 1968, Volume: 7, Issue:2

    Topics: Child Behavior Disorders; Child, Preschool; Cyanosis; Female; Humans; Infant; Male; Parent-Child Rel

1968