phenobarbital has been researched along with Chemical Dependence in 154 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomized, double-blind controlled trial is reported comparing phenobarbital and clonazepam for the purpose of sedative-hypnotic taper in inpatients with chronic, nonmalignant pain." | 9.07 | Phenobarbital versus clonazepam for sedative-hypnotic taper in chronic pain patients. A pilot study. ( Lynn, P; Roy-Byrne, P; Sullivan, M; Toshima, M, 1993) |
| " A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported." | 7.68 | Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993) |
| "A randomized, double-blind controlled trial is reported comparing phenobarbital and clonazepam for the purpose of sedative-hypnotic taper in inpatients with chronic, nonmalignant pain." | 5.07 | Phenobarbital versus clonazepam for sedative-hypnotic taper in chronic pain patients. A pilot study. ( Lynn, P; Roy-Byrne, P; Sullivan, M; Toshima, M, 1993) |
| " A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported." | 3.68 | Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993) |
| " Both of the mothers were on methadone maintenance for narcotic dependency prior to the diagnosis of pregnancy." | 3.68 | Diazepam abuse in pregnant women on methadone maintenance. Implications for the neonate. ( Hinderliter, SA; Sutton, LR, 1990) |
| " Further, this scoring system has been used by relating it to the dosage schedule of phenobarbital or paregoric as part of an ongoing research project designed to test the comparative usefulness of recommended treatments for neonates with abstinence symptoms." | 2.64 | Assessment and treatment of abstinence in the infant of the drug-dependent mother. ( Connaughton, JF; Emich, JP; Finnegan, LP; Kron, RE, 1975) |
| "The acquired immunodeficiency syndrome (AIDS) has recently emerged as a serious medical complication of parenteral substance abuse." | 2.37 | Major medical problems and detoxification treatment of parenteral drug-abusing alcoholics. ( Novick, DM, 1984) |
| "Tet alleviates the phenobarbital withdrawal symptoms and protects the brain cells against apoptosis, which may be a result of the regulation of the mRNA and protein expression levels of Bcl‑2 and Bax." | 1.42 | Protective effects of tetrandrine on brain cells in phenobarbital-dependent and -withdrawn rats. ( Fu, P; Han, B; Wang, G; Ye, Y; Zhang, H, 2015) |
| " However, there is limited data on safe and effective detoxification protocols for benzodiazepine-dependent patients." | 1.38 | Safety and effectiveness of a fixed-dose phenobarbital protocol for inpatient benzodiazepine detoxification. ( Jacapraro, JS; Kawasaki, SS; Rastegar, DA, 2012) |
| " The switch to oral agents must take into consideration the differences in potency, half-life, and oral bioavailability between the agents." | 1.29 | Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit. ( Deshpande, JK; Gregory, DF; Tobias, JD, 1994) |
| "Maternal drug addiction has increased in an alarming way over the last ten years." | 1.28 | [Newborn infant of drug-addicted mother: maternal, perinatal, neonatal aspects, and neonatal abstinence syndrome]. ( Arcas Cruz, R; Comas Mastmitja, L; Cruz Hernández, M; Figueras Aloy, J; Jiménez González, R; Vilanova Juanola, JM, 1991) |
| "A rat model of phenobarbital tolerance and physical dependence has been developed based on the 'maximally tolerable, chronically equivalent' dosing paradigm." | 1.27 | Phenobarbital tolerance and physical dependence: chronically equivalent dosing model. ( Boisse, NR; Gay, MH; Guarino, JJ; Ryan, GP, 1983) |
| " Rats were treated orally with MPB (maintenance dosage = 800 mg/kg X 2/day), PHB (100 X 2) or COD (50 X 2) twice a day (10:00 a." | 1.27 | Physical dependence on meprobamate after repeated oral administration in rats. ( Nakamura, H; Shimizu, M, 1983) |
| " The blood and brain concentrations of PhB during the dosing period were reduced abruptly on the 3rd or 4th day, corresponding well with the time course changes in the development of tolerance shown by rotarod performance." | 1.26 | Tolerance to and dependence on barbiturates in mice reference to the data in rats. ( Hiramori, T; Tagashira, E; Urano, T; Yanaura, S; Yasukouchi, K, 1981) |
| " Chronic administration of ethanol, morphine, nicotine or phenobarbitone has previously been shown to enhance rat brain 5-hydroxytryptamine (5-HT) synthesis by increasing the availability of circulating tryptophan to the brain secondarily to the NADPH-mediated inhibition of liver tryptophan pyrrolase activity." | 1.26 | Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism. ( Badawy, AA; Evans, M; Punjani, NF, 1981) |
| "Phenobarbital was given orally at a rate of 120 mg/hr until a predetermined clinical end point of phenobarbital effect was achieved." | 1.26 | Barbiturate and hypnosedative withdrawal by a multiple oral phenobarbital loading dose technique. ( Janecek, E; Robinson, GM; Sellers, EM, 1981) |
| " PhB level in the serum increased parallel to the graded increment in dosage from 0." | 1.26 | Experimental dependence on barbiturates. II. Relationship between drug levels in serum and brain and the development of dependence in rats. ( Izumi, T; Tagashira, E; Yanaura, S, 1979) |
| " Rats received phenobarbital- or barbital-admixed food on a graded-increase dosage schedule over 30-40 days." | 1.26 | Experimental barbiturate dependence. I. Barbiturate dependence development in rats by drug-admixed food (DAF) method. ( Izumi, T; Tagashira, E; Yanaura, S, 1978) |
| "Thrombocytosis was not related to withdrawal symptoms or treatment (phenobarbital or paregoric)." | 1.26 | Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users. ( Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K, 1979) |
| " Dosage supplements required can be calculated from the postinfusion rate of fall of serum phenobarbital." | 1.26 | Intravenous phenobarbital therapy in barbiturate and other hypnosedative withdrawal reactions: a kinetic approach. ( Bhushan, CM; Kapur, BM; Martin, PR; Sellers, EM; Whiteside, EA, 1979) |
| " the first dosing period was 42 dyas (6 weeks) in which drugs were repeatedly administered orally once daily, followed by a withdrawal period (7 days), the second dosing period was continued from the 50th-78th day in which the form and schedule of drug administration was as in the first dosing period." | 1.26 | [Studies on the physical dependence liability of chlorphenesin carbamate (author's transl)]. ( Aihara, H; Saito, S; Sasajima, M; Tanaka, Y; Tarumoto, Y, 1977) |
| "Generalized motor seizures and myoclonic jerks were the predominant convulsive manifestations." | 1.26 | Neonatal seizures associated with narcotic withdrawal. ( Herzlinger, RA; Kandall, SR; Vaughan, HG, 1977) |
| " The rats (drug dependence-experimented rats) who survived the first stage of this experiment were continuously subjected to re-administration by the same dosage schedule as in Exp." | 1.25 | [Comparison of development of drug dependence in naive and drug dependence-experienced rats]. ( Tagashira, E; Yanaura, S, 1975) |
| " Physical dependence on phenobarbital and diazepam was produced using the same dosage schedules as with morphine." | 1.25 | Physical dependence on morphine, phenobarbital and diazepam in rats by drug-admixed food ingestion. ( Suzuki, T; Tagashira, E; Yanaura, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 128 (83.12) | 18.7374 |
| 1990's | 15 (9.74) | 18.2507 |
| 2000's | 4 (2.60) | 29.6817 |
| 2010's | 6 (3.90) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| Sartori, S | 1 |
| Crescioli, G | 1 |
| Brilli, V | 1 |
| Traversoni, S | 1 |
| Lanzi, C | 1 |
| Vannacci, A | 1 |
| Mannaioni, G | 1 |
| Lombardi, N | 1 |
| Matsumoto, T | 1 |
| Smirk, CL | 1 |
| Bowman, E | 1 |
| Doyle, LW | 1 |
| Kamlin, O | 1 |
| Han, B | 1 |
| Fu, P | 1 |
| Ye, Y | 1 |
| Zhang, H | 1 |
| Wang, G | 1 |
| Darcın, AE | 1 |
| Dilbaz, N | 1 |
| Okay, IT | 1 |
| Kawasaki, SS | 1 |
| Jacapraro, JS | 1 |
| Rastegar, DA | 1 |
| Abdel-Latif, ME | 1 |
| Oei, J | 1 |
| Craig, F | 1 |
| Lui, K | 1 |
| SUNSHINE, I | 1 |
| BLACHLY, PH | 1 |
| BERGER, H | 1 |
| ROSENTHAL, T | 1 |
| PATRICK, SW | 1 |
| KRUG, DC | 1 |
| RIVIN, AU | 1 |
| SCHMIDT, H | 2 |
| KLEINMAN, KM | 2 |
| TYAGI, N | 1 |
| Wilding, P | 1 |
| Heath, DA | 1 |
| O'brien, CP | 2 |
| Ghoreishi, A | 1 |
| Ewart, RB | 1 |
| Priest, RG | 1 |
| Timar, M | 2 |
| Hädrich, I | 1 |
| Botez, A | 1 |
| Vrejoiu, G | 1 |
| Hawthorne, JW | 1 |
| Zabora, JR | 1 |
| D'Lugoff, BC | 1 |
| Fishman, RH | 1 |
| Yanai, J | 2 |
| Stadler, R | 1 |
| Orfanos, CE | 1 |
| Immel, C | 1 |
| Cary, PL | 1 |
| Johnson, CA | 1 |
| Foltz, RL | 1 |
| Pape, BE | 1 |
| Novick, DM | 1 |
| Finnegan, LP | 3 |
| Michael, H | 1 |
| Leifer, B | 1 |
| Desai, S | 1 |
| Yoshimura, K | 3 |
| Horiuchi, M | 1 |
| Inoue, Y | 1 |
| Yamamoto, K | 3 |
| Tagashira, E | 7 |
| Urano, T | 2 |
| Hiramori, T | 2 |
| Yanaura, S | 10 |
| Nakamura, H | 2 |
| Shimizu, M | 2 |
| Gay, MH | 1 |
| Ryan, GP | 1 |
| Boisse, NR | 1 |
| Guarino, JJ | 1 |
| Cohen, MS | 1 |
| Mackenzie, TB | 1 |
| Collins, NM | 1 |
| Popkin, ME | 1 |
| Blum, K | 1 |
| Cull, DL | 1 |
| Briggs, AH | 1 |
| Tang, M | 1 |
| Ahrendsen, K | 1 |
| Falk, JL | 1 |
| Belknap, JK | 3 |
| Mitchell, MA | 2 |
| Yasukouchi, K | 1 |
| Badawy, AA | 1 |
| Evans, M | 1 |
| Punjani, NF | 1 |
| Kulik, AV | 1 |
| Wilbur, R | 1 |
| Robinson, GM | 1 |
| Sellers, EM | 3 |
| Janecek, E | 1 |
| Richens, A | 1 |
| Oxley, J | 1 |
| George, S | 1 |
| Braithwaite, RA | 1 |
| Kostadinova, I | 1 |
| Millusheva, M | 1 |
| Tobias, JD | 1 |
| Deshpande, JK | 1 |
| Gregory, DF | 1 |
| Sullivan, M | 1 |
| Toshima, M | 1 |
| Lynn, P | 1 |
| Roy-Byrne, P | 1 |
| Kimura, T | 1 |
| Miyaoka, T | 1 |
| Saunders, PA | 1 |
| Baker, ML | 1 |
| Hume, AS | 1 |
| Yamamoto, I | 1 |
| Ho, IK | 1 |
| Murphy, JL | 1 |
| Aoki, K | 2 |
| Yoshida, T | 4 |
| Kuroiwa, Y | 3 |
| Tanaka, S | 3 |
| Kiuchi, Y | 1 |
| Numazawa, S | 2 |
| Oguchi, K | 1 |
| Prater, CD | 1 |
| Miller, KE | 1 |
| Zylstra, RG | 1 |
| Smith, MA | 1 |
| Stoops, WW | 1 |
| Okuno, Y | 1 |
| Yamamoto, T | 1 |
| Shioda, S | 1 |
| Izumi, T | 2 |
| Hanson, HM | 1 |
| Ivester, CA | 1 |
| Morton, BR | 1 |
| Waddingham, S | 2 |
| Riffee, WR | 1 |
| Sheppard, JR | 1 |
| Suzuki, T | 4 |
| Mito, H | 1 |
| Shishido, A | 1 |
| Kobayashi, N | 1 |
| Ondrusek, G | 1 |
| Berg, J | 1 |
| Burstein, Y | 1 |
| Giardina, PJ | 1 |
| Rausen, AR | 1 |
| Kandall, SR | 4 |
| Siljestrom, K | 1 |
| Peterson, CM | 1 |
| Martin, PR | 1 |
| Bhushan, CM | 1 |
| Kapur, BM | 2 |
| Whiteside, EA | 1 |
| Franks, RD | 1 |
| Sasajima, M | 1 |
| Tarumoto, Y | 1 |
| Aihara, H | 1 |
| Tanaka, Y | 1 |
| Saito, S | 1 |
| Tabakoff, B | 1 |
| Ritzmann, RF | 1 |
| Madden, JD | 1 |
| Lefkowitz, SS | 1 |
| Nemeth, D | 1 |
| Herzlinger, RA | 1 |
| Vaughan, HG | 1 |
| Greer, CA | 1 |
| Alpern, HP | 1 |
| Collins, AC | 1 |
| Kron, RE | 2 |
| Connaughton, JF | 1 |
| Emich, JP | 1 |
| Kopelman, AE | 1 |
| Spiehler, V | 1 |
| Bosl, R | 1 |
| Shideman, JR | 1 |
| Meyer, RM | 1 |
| Buselmeier, TJ | 1 |
| von Hartitzsch, B | 1 |
| Kjellstrand, CM | 1 |
| Tagashire, E | 1 |
| Banerjee, U | 3 |
| Litt, M | 1 |
| Woody, GE | 2 |
| Greenstein, R | 1 |
| Alexander, GJ | 1 |
| Satoh, T | 1 |
| Smith, DE | 6 |
| Landry, MJ | 1 |
| Arcas Cruz, R | 1 |
| Figueras Aloy, J | 1 |
| Vilanova Juanola, JM | 1 |
| Comas Mastmitja, L | 1 |
| Jiménez González, R | 1 |
| Cruz Hernández, M | 1 |
| Yutrzenka, GJ | 2 |
| Patrick, GA | 1 |
| Rosenberger, W | 1 |
| Sutton, LR | 1 |
| Hinderliter, SA | 1 |
| Ravi, NV | 1 |
| Maany, I | 1 |
| Burke, WM | 1 |
| Dhopesh, V | 1 |
| Löscher, W | 1 |
| Hönack, D | 1 |
| Gomez, J | 1 |
| Rodriguez, A | 1 |
| Kosse, K | 1 |
| Devenyi, P | 1 |
| Rideout, J | 1 |
| Schneiderman, J | 1 |
| Buckley, PF | 1 |
| Sizemore, WA | 1 |
| Charlton, EJ | 1 |
| Fikr, V | 1 |
| Budka, I | 1 |
| Stika, L | 1 |
| Groh, KR | 1 |
| Ehret, CF | 1 |
| Peraino, C | 1 |
| Meinert, JC | 1 |
| Readey, MA | 1 |
| Thomas, D | 1 |
| Fortenberry, JC | 1 |
| Brown, DB | 1 |
| Shevlin, LT | 1 |
| Weinberger, SM | 1 |
| Doberczak, TM | 1 |
| Thornton, JC | 1 |
| Bernstein, J | 1 |
| Sullivan, JT | 1 |
| Daniel, DG | 1 |
| Rabin, PL | 1 |
| Basu, PK | 1 |
| Matuk, Y | 1 |
| McCulloch, C | 1 |
| Peris, J | 1 |
| Harris, RA | 1 |
| Bailey, DN | 1 |
| Jatlow, PI | 1 |
| Wesson, DR | 4 |
| Lerner, SE | 1 |
| Kettner, VR | 1 |
| Hancock, BW | 1 |
| Haider, I | 1 |
| Oswald, I | 1 |
| Zelson, C | 1 |
| Fink, RD | 1 |
| Knott, DH | 1 |
| Beard, JD | 1 |
| Malcolm, MT | 1 |
| Smith, SE | 1 |
| Freund, G | 1 |
| Lipsitz, PJ | 1 |
| Blatman, S | 1 |
| Gascon, GG | 1 |
| Bleyer, WA | 1 |
| Marshall, RE | 1 |
| Frings, CS | 1 |
| Queen, CA | 1 |
| Crowley, TJ | 1 |
| Kaneto, H | 1 |
| Koida, M | 1 |
| Tsuchie, F | 1 |
| Miller, WL | 1 |
| Kullberg, MP | 1 |
| Banning, ME | 1 |
| Brown, LD | 1 |
| Doctor, BP | 1 |
| Bastos, ML | 1 |
| Jukofsky, D | 1 |
| Mulé, SJ | 1 |
| Choulis, NH | 1 |
| Carroll, HG | 1 |
| Abel, GG | 1 |
| Moldéus, P | 1 |
| Grundin, R | 1 |
| von Bahr, C | 1 |
| Orrenius, S | 1 |
| Gartner, LM | 1 |
| Klein, B | 1 |
| Sheehan, JE | 1 |
| Grunberg, E | 1 |
| Walberg, CB | 1 |
| Snodgrass, GJ | 1 |
| Glass, L | 2 |
| Rothstein, P | 1 |
| Gould, JB | 1 |
| Puri, SK | 1 |
| Lal, H | 1 |
| Kohli, RP | 1 |
| Singh, N | 1 |
| Kulshrestha, VK | 1 |
| Yanagita, T | 1 |
| Takahashi, S | 1 |
| Desmond, MM | 1 |
| Schwanecke, RP | 1 |
| Wilson, GS | 1 |
| Yasunaga, S | 1 |
| Burgdorff, I | 1 |
| Hasse, HE | 1 |
| Schiefgen, W | 1 |
| Schönhöfer, P | 1 |
| Gray, GR | 1 |
| Sheppard, CW | 1 |
| Evans, HE | 1 |
| Reddy, AM | 1 |
| Harper, RG | 1 |
| Stern, G | 1 |
| Watson, JP | 1 |
| Radford, MD | 1 |
| Wilson, JT | 1 |
| Chambers, CD | 1 |
| Brill, L | 1 |
| Montalvo, JG | 1 |
| Klein, E | 1 |
| Eyer, D | 1 |
| Harper, B | 1 |
| Goldman, D | 1 |
| Teitelbaum, DT | 1 |
| Vaag, UH | 1 |
| Jones, MD | 1 |
| Helfer, RE | 1 |
| Cramond, WA | 1 |
| Milner, G | 1 |
| Battegay, R | 1 |
| Ladewig, D | 1 |
| Kahn, EJ | 1 |
| Neumann, LL | 1 |
| Polk, GA | 1 |
| Glasson, B | 1 |
| Stewart, A | 1 |
| Licurici, V | 1 |
| Lazarescu, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Long Term of Benzodiazepine Use on Psychiatric Manifestation in Neuropsychiatric Disease[NCT04792658] | 100 participants (Anticipated) | Observational | 2021-03-10 | Not yet recruiting | |||
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for phenobarbital and Chemical Dependence
| Article | Year |
|---|---|
Benzodiazepine use, abuse, and dependence.
Topics: Anti-Anxiety Agents; Benzodiazepines; Delayed-Action Preparations; Humans; Long-Term Care; Phenobarb | 2005 |
Long-lasting effects of early barbiturates on central nervous system and behavior.
Topics: Animals; Barbiturates; Behavior, Animal; Brain; Cell Differentiation; Drug Tolerance; Enzyme Inducti | 1983 |
Major medical problems and detoxification treatment of parenteral drug-abusing alcoholics.
Topics: Acquired Immunodeficiency Syndrome; Alcoholism; Homosexuality; Humans; Hypnotics and Sedatives; Infe | 1984 |
Drug abuse in pregnancy: fetal ad neonatal effects.
Topics: Alcoholism; Birth Weight; Chlorpromazine; Diazepam; Female; Fetus; Humans; Infant, Newborn; Infant, | 1982 |
Outpatient detoxification of the addicted or alcoholic patient.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Ambulatory Care; Anti-Anxiety Agents; Chlordiaz | 1999 |
Benzodiazepine dependency discontinuation: focus on the chemical dependency detoxification setting and benzodiazepine-polydrug abuse.
Topics: Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule | 1990 |
Epilepsy in the adolescent.
Topics: Acetazolamide; Adolescent; Age Factors; Alcoholic Intoxication; Amphetamine; Anticonvulsants; Attitu | 1974 |
3 trials available for phenobarbital and Chemical Dependence
| Article | Year |
|---|---|
Phenobarbital versus clonazepam for sedative-hypnotic taper in chronic pain patients. A pilot study.
Topics: Adult; Anxiety Disorders; Chronic Disease; Clonazepam; Double-Blind Method; Female; Hospitalization; | 1993 |
Assessment and treatment of abstinence in the infant of the drug-dependent mother.
Topics: Clinical Trials as Topic; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Opium; Phenoba | 1975 |
The course of the heroin withdrawal syndrome in newborn infants treated with phenobarbital or chlorpromazine.
Topics: Chlorpromazine; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbi | 1969 |
144 other studies available for phenobarbital and Chemical Dependence
| Article | Year |
|---|---|
Phenobarbital use in benzodiazepine and z-drug detoxification: a single-centre 15-year observational retrospective study in clinical practice.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Humans; Male; Phenobarbital; Retrospective Studies; Subs | 2022 |
Harm caused by "Vegetamin": From the viewpoint of drug abuse and dependence.
Topics: Chlorpromazine; Drug Combinations; Humans; Phenobarbital; Sleep Wake Disorders; Substance-Related Di | 2017 |
Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment.
Topics: Adult; Analgesics, Opioid; Breast Feeding; Cost Control; Female; Home Care Services, Hospital-Based; | 2014 |
Protective effects of tetrandrine on brain cells in phenobarbital-dependent and -withdrawn rats.
Topics: Animals; bcl-2-Associated X Protein; Benzylisoquinolines; Brain; Disease Models, Animal; Drugs, Chin | 2015 |
Barbexaclone abuse in a cannabis ex-user.
Topics: Adult; Anticonvulsants; Humans; Male; Marijuana Abuse; Phenobarbital; Substance-Related Disorders | 2010 |
Safety and effectiveness of a fixed-dose phenobarbital protocol for inpatient benzodiazepine detoxification.
Topics: Adult; Benzodiazepines; Dose-Response Relationship, Drug; Electronic Health Records; Female; GABA Mo | 2012 |
Profile of infants born to drug-using mothers: a state-wide audit.
Topics: Australian Capital Territory; Breast Feeding; Congenital Abnormalities; Female; Hospitalization; Hos | 2013 |
Chemical evidence of tolerance to phenobarbital.
Topics: Behavior, Addictive; Drug Tolerance; Humans; Immune Tolerance; Phenobarbital; Substance-Related Diso | 1957 |
PROCEDURE FOR WITHDRAWAL OF BARBITURATES.
Topics: Aged; Barbiturates; Depression; Electroconvulsive Therapy; Humans; Phenobarbital; Phenothiazines; Sc | 1964 |
TREATMENT OF NARCOTIC ADDICTS IN PRIVATE PRACTICE.
Topics: Chlordiazepoxide; Chlorpromazine; Drug Therapy; Family Practice; General Practice; Glucose; Hospital | 1964 |
CONGENITAL NEONATAL NARCOTICS ADDICTION: A NATURAL HISTORY.
Topics: Chlorpromazine; Female; Humans; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine Dependence; | 1964 |
FALSE ENDOCRINE TEST RESULTS DUE TO DRUGS.
Topics: 17-Ketosteroids; Aspirin; Diagnosis, Differential; Hypnotics and Sedatives; Hypopituitarism; Hypothy | 1964 |
EFFECT OF CHRONIC ADMINISTRATION AND WITHDRAWAL OF BARBITURATES UPON DRINKING IN THE RAT.
Topics: Alcohol Drinking; Barbiturates; Phenobarbital; Rats; Research; Substance Withdrawal Syndrome; Substa | 1964 |
PHENOBARBITONE AND HAIR GROWTH.
Topics: Hair; Pharmacology; Phenobarbital; Substance-Related Disorders; Toxicology | 1964 |
Effect of paracetamol on uric acid determination.
Topics: Acetaminophen; Adult; Anticonvulsants; Autoanalysis; Bromides; Diazepam; Dose-Response Relationship, | 1975 |
A somatic type delusional disorder secondary to peripheral neuropathy: a case report.
Topics: Adult; Amitriptyline; Biperiden; Brachial Plexus; Delusions; Drug Overdose; Drug Therapy, Combinatio | 2008 |
Methaqualone addiction and delirium tremens.
Topics: Humans; Male; Methaqualone; Middle Aged; Paraldehyde; Phenobarbital; Promazine; Psychoses, Alcoholic | 1967 |
[Role of the granulopexic function of the reticulo-histiocytic system (SRH) in the installation mechanism of habituation to phenobarbital].
Topics: Animals; Female; Guinea Pigs; Humans; Ink; Male; Mononuclear Phagocyte System; Phenobarbital; Rats; | 1967 |
Out-patient detoxification of patients addicted to sedative-hypnotics and anxiolytics.
Topics: Ambulatory Care; Anti-Anxiety Agents; Follow-Up Studies; Humans; Hypnotics and Sedatives; Phenobarbi | 1982 |
[Drug-induced pellagra].
Topics: Diazepam; Female; Humans; Middle Aged; Niacinamide; Pellagra; Phenacetin; Phenobarbital; Salicylamid | 1982 |
Driving under the influence of phenobarbital.
Topics: Accidents, Traffic; Adult; Automobile Driving; Dronabinol; Female; Humans; Phenobarbital; Substance- | 1983 |
An evaluation of neonatal abstinence treatment modalities.
Topics: Central Nervous System Depressants; Diazepam; Drug Therapy, Combination; Humans; Infant, Newborn; In | 1984 |
[Pharmacological studies on drug dependence. (III): Intravenous self-administration of some CNS-affecting drugs and a new sleep-inducer, 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), in rats].
Topics: Animals; Central Nervous System Agents; Cocaine; Diazepam; Humans; Hypnotics and Sedatives; Injectio | 1984 |
Cross-physical dependence liability of psychotropic drugs in rats dependent on barbiturates.
Topics: Animals; Body Weight; Humans; Phenobarbital; Psychotropic Drugs; Rats; Rats, Inbred Strains; Substan | 1983 |
Persistence of drug experience in rats formerly dependent on phenobarbital or meprobamate.
Topics: Animals; Body Temperature; Body Weight; Codeine; Humans; Male; Meprobamate; Phenobarbital; Rats; Rat | 1983 |
Phenobarbital tolerance and physical dependence: chronically equivalent dosing model.
Topics: Animals; Central Nervous System; Drug Tolerance; Humans; Male; Phenobarbital; Rats; Rats, Inbred Str | 1983 |
Physical dependence on meprobamate after repeated oral administration in rats.
Topics: Administration, Oral; Animals; Body Temperature; Body Weight; Codeine; Humans; Male; Meprobamate; Ph | 1983 |
A case of fetal abuse?
Topics: Adult; Alcoholism; Child Abuse; Chlorthalidone; Female; Fetus; Humans; Maternal-Fetal Relations; Mor | 1982 |
An improved technique for the induction of barbiturate dependence in mice.
Topics: Animals; Barbiturates; Disease Models, Animal; Feeding Behavior; Humans; Mice; Mice, Inbred Strains; | 1980 |
[Neuropharmacological studies on drug dependence (II). Changes in spontaneous motor activity, EEG and brain monoamines during the period of dependence development and of abrupt withdrawal in rats, with special reference to circadian rhythm (author's trans
Topics: Animals; Biogenic Amines; Brain; Circadian Rhythm; Cocaine; Diazepam; Electroencephalography; Humans | 1980 |
Barbiturate dependence and drug preference.
Topics: Animals; Barbiturates; Choice Behavior; Humans; Male; Phenobarbital; Rats; Reinforcement Schedule; S | 1981 |
Barbiturate physical dependence in mice: effects on body temperature regulation.
Topics: Animals; Barbiturates; Behavior, Animal; Body Temperature Regulation; Humans; Male; Mice; Mice, Inbr | 1981 |
Tolerance to and dependence on barbiturates in mice reference to the data in rats.
Topics: Animals; Brain Chemistry; Drug Tolerance; Humans; Male; Mice; Mice, Inbred ICR; Phenobarbital; Prohi | 1981 |
Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.
Topics: Animals; Brain; Corticosterone; Ethanol; Humans; Liver; Naloxone; Nicotine; Phenobarbital; Rats; Ser | 1981 |
Delirium and stereotypy from anticholinergic antiparkinson drugs.
Topics: Adult; Aged; Benztropine; Delirium; Diazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; E | 1982 |
Barbiturate and hypnosedative withdrawal by a multiple oral phenobarbital loading dose technique.
Topics: Administration, Oral; Adolescent; Adult; Aged; Barbiturates; Female; Half-Life; Humans; Hypnotics an | 1981 |
Phenobarbitone and epilepsy.
Topics: Drug Prescriptions; Epilepsy; Humans; Legislation, Drug; Phenobarbital; Substance-Related Disorders; | 1980 |
Drugs of abuse screening in the West Midlands: a 6 year retrospective survey of results.
Topics: Amphetamine; Cannabinoids; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Illicit Drugs; Long | 1994 |
Changes in phenamine effects after repeated treatment and subsequent withdrawal of phenobarbital, carbamazepine and a combination of both.
Topics: Amphetamine; Animals; Carbamazepine; Drug Interactions; Drug Tolerance; Male; Phenobarbital; Rats; R | 1993 |
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.
Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; | 1994 |
Induction of tolerance to and physical dependence on pentobarbital continuous intracerebroventricular administration.
Topics: Animals; Body Temperature; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convu | 1993 |
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ket | 1993 |
Forensic immunochemistry.
Topics: Central Nervous System Agents; Cocaine; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Humans | 1996 |
Changes in glutamate receptors, c-fos mRNA expression and activator protein-1 (AP-1) DNA binding activity in the brain of phenobarbital-dependent and -withdrawn rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Brain; Dizocilpine Maleate; DNA-Bin | 1997 |
Sensitivity to the effects of sedative-hypnotics on motor performance: influence of task difficulty and chronic phenobarbital administration.
Topics: Amobarbital; Animals; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Dru | 2001 |
Brain responses to acute withdrawal in phenobarbital-dependent rats.
Topics: Animals; Anticonvulsants; Brain; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonis | 2001 |
Experimental dependence on barbiturates. II. Relationship between drug levels in serum and brain and the development of dependence in rats.
Topics: Animals; Barbiturates; Body Weight; Circadian Rhythm; Feeding Behavior; Humans; Male; Motor Skills; | 1979 |
Nicotine self-administration in rats.
Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; | 1979 |
Barbiturate dependence in mice: evidence for beta-adrenergic receptor proliferation in brain.
Topics: Alprenolol; Animals; Barbiturates; Brain; Cell Membrane; Cerebral Cortex; Humans; Mice; Mice, Inbred | 1978 |
[Changes in the osmotic fragility of erythrocyte membrane in morphine- and phenobarbital-dependent rats (author's transl)].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Fasting; Humans; Male; Morphine Dependence; Or | 1979 |
Barbiturate dependence in mice: effects of continuous vs. discontinuous drug administration.
Topics: Animals; Brain; Drug Administration Schedule; Drug Tolerance; Humans; Male; Mice; Mice, Inbred DBA; | 1977 |
Experimental barbiturate dependence. I. Barbiturate dependence development in rats by drug-admixed food (DAF) method.
Topics: Animal Feed; Animals; Barbiturates; Behavior, Animal; Humans; Male; Phenobarbital; Postural Balance; | 1978 |
Barbiturate withdrawal.
Topics: Administration, Oral; Barbiturates; Humans; Phenobarbital; Substance Withdrawal Syndrome; Substance- | 1979 |
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, | 1979 |
Intravenous phenobarbital therapy in barbiturate and other hypnosedative withdrawal reactions: a kinetic approach.
Topics: Adult; Barbiturates; Female; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Male; Middle Ag | 1979 |
The overtranquilized patient.
Topics: Humans; Pentobarbital; Phenobarbital; Psychotherapy; Substance Withdrawal Syndrome; Substance-Relate | 1979 |
[Studies on the physical dependence liability of chlorphenesin carbamate (author's transl)].
Topics: Animals; Behavior, Animal; Body Weight; Chlorphenesin; Dogs; Eating; Humans; Male; Phenobarbital; Su | 1977 |
Cross-dependence between phenobarbital and alcohol in rats.
Topics: Alcoholism; Animals; Body Weight; Humans; Male; Phenobarbital; Rats; Substance Withdrawal Syndrome; | 1977 |
Brain noradrenergic systems as a prerequisite for developing tolerance to barbiturates.
Topics: Animals; Behavior, Animal; Body Temperature Regulation; Brain; Drug Tolerance; Humans; Hydroxydopami | 1978 |
[Neuropharmacological studies on drug dependence (I). Effects due to the difference in strain, sex and drug administration time on physical dependence development and characteristics of withdrawal signs in CNS-affecting drug dependent rats (author's trans
Topics: Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Body Weight; Conditioning, Classica | 1979 |
Problems pertaining to the care of newborn infants of drug-addicted women.
Topics: Apnea; Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Narcotics; P | 1978 |
Immunosuppression of rosette-forming cells.
Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; | 1976 |
Neonatal seizures associated with narcotic withdrawal.
Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Opium; Phenobarbital; Pregnanc | 1977 |
Increased CNS sensitivity to flurothyl as a measure of physical dependence in mice following morphine, phenobarbital, and ethanol treatment.
Topics: Animals; Ethanol; Flurothyl; Humans; Male; Mice; Mice, Inbred C57BL; Morphine Dependence; Phenobarbi | 1976 |
Fetal addiction to pentazocine.
Topics: Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pentazoc | 1975 |
Drugs of abuse radioimmunoassay directory.
Topics: Amphetamine; Atropine; Barbiturates; Cannabis; Humans; Lysergic Acid Diethylamide; Mescaline; Morphi | 1975 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote | 1975 |
[Comparison of development of drug dependence in naive and drug dependence-experienced rats].
Topics: Administration, Oral; Animals; Body Weight; Chlordiazepoxide; Diazepam; Eating; Female; Humans; Male | 1975 |
[Dependence on and preference for morphine (II). Comparison among morphine, phenobarbital and diazepam].
Topics: Animals; Body Weight; Choice Behavior; Decision Making; Diazepam; Female; Humans; Male; Methods; Mor | 1975 |
Conditioned learning in young rats born of drug-addicted parents and raised on addictive drugs.
Topics: Animals; Animals, Newborn; Avoidance Learning; Birth Weight; Body Weight; Conditioning, Psychologica | 1975 |
Narcotic addiction in the newborn: differences in behavior generated by methadone and heroin.
Topics: Adaptation, Physiological; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, New | 1975 |
Misuse and abuse of diazepam: an increasingly common medical problem.
Topics: Adult; Diazepam; Drug Prescriptions; Heroin Dependence; Humans; Legislation, Drug; Male; Methadone; | 1975 |
Physical dependence on morphine, phenobarbital and diazepam in rats by drug-admixed food ingestion.
Topics: Animals; Body Weight; Diazepam; Diet; Feeding Behavior; Female; Humans; Levallorphan; Male; Morphine | 1975 |
Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.
Topics: Amphetamine; Animals; Avoidance Learning; Body Weight; Conditioning, Operant; Dose-Response Relation | 1975 |
Direct use of ion-exchange papers in hemagglutination-inhibition tests for drug abuse.
Topics: Aspirin; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Hemagglutinat | 1976 |
Characteristic changes of the GABAA receptor in the brain of phenobarbital-dependent and withdrawn rats.
Topics: Animals; Brain; Male; Membranes; Muscimol; Phenobarbital; Rats; Receptors, GABA-A; Substance Withdra | 1991 |
[Newborn infant of drug-addicted mother: maternal, perinatal, neonatal aspects, and neonatal abstinence syndrome].
Topics: Adult; Chlorpromazine; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Neonatal Abstinenc | 1991 |
Substitution of psychoactive drugs in pentobarbital-dependent rats.
Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-R | 1990 |
Diazepam abuse in pregnant women on methadone maintenance. Implications for the neonate.
Topics: Adult; Diazepam; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infant, Newborn, Diseas | 1990 |
Detoxification with phenobarbital of alprazolam-dependent polysubstance abusers.
Topics: Adult; Alprazolam; Combined Modality Therapy; Follow-Up Studies; Humans; Illicit Drugs; Male; Methad | 1990 |
Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Electrodes, Implanted; Female; Kindling, Neuro | 1989 |
An evaluation of the results of a drug sample analysis.
Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Metha | 1989 |
Dependence on phenobarbital but not pentobarbital using drug-adulterated food.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Food Contamination; Male; M | 1989 |
Abuse of a commonly prescribed analgesic preparation.
Topics: Adult; Analgesics, Opioid; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Female; Huma | 1985 |
Medication management in patients with chronic non-malignant pain. A review of the use of a drug withdrawal protocol.
Topics: Analgesics, Opioid; Chronic Disease; Drug Combinations; Humans; Hypnotics and Sedatives; Methadone; | 1986 |
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combina | 1988 |
Circadian manifestations of barbiturate habituation, addiction and withdrawal in the rat.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Habituation, Psychophysiologic; | 1988 |
Infants of drug-addicted mothers.
Topics: Acquired Immunodeficiency Syndrome; Female; Humans; Infant; Infant, Newborn; Neonatal Abstinence Syn | 1988 |
Analysis of drug involvement in traffic fatalities in Alabama.
Topics: Accidents, Traffic; Alabama; Cannabinoids; Dextropropoxyphene; Diazepam; Ethanol; Humans; Methaqualo | 1986 |
Early weight-change patterns in neonatal abstinence.
Topics: Birth Weight; Body Weight; Energy Intake; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exch | 1986 |
Treatment of the barbiturate abstinence syndrome.
Topics: Barbiturates; Drug Administration Schedule; Drug Tolerance; Humans; Pentobarbital; Phenobarbital; Su | 1986 |
Disguises of delirium.
Topics: Adult; Aged; Brain Diseases; Delirium; Diagnosis, Differential; Drug-Related Side Effects and Advers | 1985 |
Suitability of corneal grafts from donors treated with chemical agents.
Topics: Animals; Cornea; Corneal Transplantation; Ethanol; Graft Rejection; Guinea Pigs; Humans; Morphine; P | 1985 |
Barbiturate tolerance and dependence: effects on synaptosomal sodium transport and membrane fluidity.
Topics: Animals; Barbiturates; Biological Transport, Active; Drug Tolerance; Ethanol; Fluorescence Polarizat | 1985 |
Methaqualone overdose: analytical methodology, and the significance of serum drug concentrations.
Topics: Alcohol Drinking; Alkanes; Chloroform; Chromatography, Gas; Chromatography, Thin Layer; Consciousnes | 1973 |
Treatment of polydrug users in San Francisco.
Topics: Adult; Aftercare; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; California; Crisis Intervention; | 1974 |
Acute barbiturate poisoning in young epileptics.
Topics: Adolescent; Child; Coma; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenobarbital; Substance-Rela | 1974 |
Late brain recovery processes after drug overdose.
Topics: Adult; Benzazepines; Brain; Delirium; Drug Tolerance; Electroencephalography; Female; Humans; Hypnot | 1970 |
Infant of the addicted mother.
Topics: Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Disea | 1973 |
Sedative-hypnotic dependence.
Topics: Attitude of Health Personnel; Attitude to Health; Diazepam; Dose-Response Relationship, Drug; Drug P | 1974 |
[Drug dependence in rats: substitution test and sequential changes in body weight].
Topics: Animals; Body Weight; Codeine; Drug Therapy, Combination; Humans; Male; Meprobamate; Morphine; Morph | 1974 |
Programmed self-administration of potentially addictive drugs in young rats and its effects on learning.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Drug Tolerance; Ethanol; Extinction, Psy | 1974 |
Temporal lobe epilepsy due to drug withdrawal.
Topics: Barbiturates; Diazepam; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged | 1972 |
Taste thresholds in drug addicts and alcoholics.
Topics: Adult; Alcoholism; Amphetamine; Female; Humans; Male; Nicotiana; Phenobarbital; Plants, Toxic; Quini | 1972 |
Alcohol, barbiturate, and bromide withdrawal syndromes in mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Barbiturates; Body Weight; Bromides; Diet; Disease Models, An | 1973 |
Newborn infants of mothers on methadone maintenance.
Topics: Body Weight; Camphor; Diazepam; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, D | 1974 |
Barbiturate withdrawal syndrome in a passively addicted infant.
Topics: Cesarean Section; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Infant, Newborn; I | 1972 |
Stability of certain drugs of abuse in urine specimens.
Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical P | 1972 |
Dose-dependent facilitation or supression of rat fighting by methamphetamine, phenobarbital, or imipramine.
Topics: Aggression; Animals; Behavior, Animal; Depression, Chemical; Humans; Imipramine; Male; Methamphetami | 1972 |
[Tolerance and physical dependence producing liability of doxepin].
Topics: Amitriptyline; Animals; Body Weight; Diazepam; Dibenzoxepins; Drug Resistance; Humans; Imipramine; M | 1972 |
Studies on the quantitative extraction of morphine from urine using nonionic XAD-2 resin.
Topics: 1-Propanol; Adult; Amphetamine; Carbon Isotopes; Chromatography; Chromatography, Thin Layer; Evaluat | 1973 |
Routine identification of drugs of abuse in human urine. 3. Differential elution of the XAD-2 resin.
Topics: Amitriptyline; Amphetamine; Barbiturates; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Hy | 1973 |
Separation and quantitation of mixtures of the most commonly abused drugs.
Topics: Amobarbital; Cannabis; Chromatography, Thin Layer; Dextroamphetamine; Ephedrine; Humans; Indicators | 1973 |
Chronic gasoline inhalation.
Topics: Adolescent; Delirium; Humans; Intellectual Disability; Lead; Male; Movement Disorders; Petroleum; Ph | 1973 |
Spectral studies on drug-cytochrome P-450 interaction in isolated rat liver cells.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Hexobarbital; Humans; Kinetics; Lidocaine; L | 1973 |
Late presentation of drug withdrawal symptoms in newborns.
Topics: Birth Weight; Camphor; Diazepam; Female; Gestational Age; Heroin Dependence; Humans; Infant; Infant, | 1974 |
Use of fluorescamine ("Fluram") to detect amphetamine in urine by thin-layer chromatography.
Topics: Amphetamine; Benzofurans; Chromatography, Ion Exchange; Chromatography, Thin Layer; Drug Stability; | 1974 |
Correlation of the "EMIT" urine barbiturate assay with a spectrophotometric serum barbiturate assay in suspected overdose.
Topics: Amobarbital; Barbiturates; Evaluation Studies as Topic; Humans; Methods; Pentobarbital; Phenobarbita | 1974 |
Seizures in newborn infants.
Topics: Birth Injuries; Brain; Calcium; Diazepam; Gluconates; Glucose; Humans; Hypocalcemia; Hypoxia; Infant | 1974 |
Narcotic withdrawal in the newborn infant.
Topics: Diazepam; Female; Fetus; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mate | 1974 |
Born with a habit. Infants of drug-addicted mothers.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Dia | 1974 |
Reduced threshold to pain induced aggression specifically related to morphine dependence.
Topics: Aggression; Animals; Dextroamphetamine; Drug Synergism; Electroshock; Ethanol; Humans; Male; Morphin | 1974 |
An experimental investigation of dependence liability of methaqualone in rats.
Topics: Acoustic Stimulation; Animals; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drug | 1974 |
Development of tolerance to and physical dependence on barbiturates in rhesus monkeys.
Topics: Animals; Barbiturates; Central Nervous System; Drug Tolerance; Female; Haplorhini; Humans; Male; Phe | 1970 |
Maternal barbiturate utilization and neonatal withdrawal symptomatology.
Topics: Anticonvulsants; Apgar Score; Barbiturates; Epilepsy; Female; Gestational Age; Heroin; Humans; Infan | 1972 |
[Emergencies in drugged adolescents].
Topics: Adolescent; Amitriptyline; Benzazepines; Cannabis; Emergencies; Hallucinogens; Humans; Male; Morphin | 1972 |
Outpatient barbiturate withdrawal using phenobarbital.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Amobarbital; Barbiturates; Community Healt | 1972 |
Narcotic withdrawal in the newborn.
Topics: Birth Weight; Chlorpromazine; Cocaine; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, N | 1972 |
Observations on heroin and methadone withdrawal in the newborn.
Topics: Adolescent; Adult; Apgar Score; Birth Weight; Female; Heroin; Humans; Infant, Newborn; Infant, Newbo | 1971 |
Blood barbiturate levels in a patient dependent upon amylobarbitone sodium.
Topics: Administration, Oral; Amobarbital; Barbiturates; Female; Humans; Middle Aged; Phenobarbital; Substan | 1971 |
Caution with phenobarbital.
Topics: Drug Interactions; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Phenobar | 1971 |
Some considerations for the treatment of non-narcotic drug abusers.
Topics: Amphetamine; Hallucinogens; Humans; Hypnotics and Sedatives; Interpersonal Relations; Lysergic Acid | 1971 |
Identification of drugs of abuse in urine. I. A study of the Dole technique.
Topics: Amphetamine; Analgesics; Chromatography, Ion Exchange; Fluorescence; Humans; Methods; Narcotics; Phe | 1970 |
A new method for treatment of barbiturate dependence.
Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital; | 1970 |
Treatment of barbiturate dependence.
Topics: Barbiturates; Female; Humans; Male; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related | 1970 |
[Slight abstinence symptoms].
Topics: Adult; Analgesics; Diazepam; Female; Humans; Phenobarbital; Substance Withdrawal Syndrome; Substance | 1970 |
Phenobarbital technique for treatment of barbiturate dependence.
Topics: Adult; Barbiturates; Female; Humans; Hypnotics and Sedatives; Male; Phenobarbital; Substance Withdra | 1971 |
A teething lotion resulting in the misdiagnosis of diphenylhydantoin administration.
Topics: Blood Chemical Analysis; Child Abuse; Condiments; Humans; Infant; Male; Methods; Phenobarbital; Phen | 1971 |
Organic psychosis.
Topics: Adolescent; Adult; Aged; Barbiturates; Brain Neoplasms; Bronchopneumonia; Carbon Monoxide Poisoning; | 1968 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine | 1968 |
[On psychoses caused by drugs against motion sickness--current drug addiction trends in adolescents].
Topics: Adolescent; Amphetamine; Atropine; Female; Humans; Male; Phenobarbital; Psychoses, Substance-Induced | 1968 |
[Services and perspectives of metabolic research on certain exogenous substances endowed with pharmacological activity].
Topics: Animals; Carbon Tetrachloride Poisoning; Humans; Microsomes; Pentobarbital; Pharmacology; Phenobarbi | 1965 |
Effect of prior injection upon the subsequent drinking of phenobarbital in the rat.
Topics: Animals; Female; Humans; Injections, Subcutaneous; Male; Phenobarbital; Rats; Substance Withdrawal S | 1966 |
[Incoporation of barbital C-14 in rats in conditions of habituation to certain barbiturates].
Topics: Acetazolamide; Animals; Carbon Isotopes; Histamine; Histiocytes; Humans; Liver; Methylcellulose; Mon | 1966 |