phenobarbital has been researched along with Central Nervous System Disease in 12 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to use these effectively, the critical care nurse must be aware of the indications and controversies surrounding their use, the patho-physiologic conditions that impact on the disposition, and appropriate dosing and monitoring of these agents in the critical care setting." | 2.38 | Anticonvulsants: pharmacotherapeutic issues in the critically ill patient. ( Dupuis, RE; Miranda-Massari, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birkler, RI | 1 |
| Telving, R | 1 |
| Ingemann-Hansen, O | 1 |
| Charles, AV | 1 |
| Johannsen, M | 1 |
| Andreasen, MF | 1 |
| KANE, FJ | 1 |
| MCCURDY, RL | 1 |
| HANSEN, HA | 1 |
| NORDQVIST, P | 1 |
| SOURANDER, P | 1 |
| Dupuis, RE | 1 |
| Miranda-Massari, J | 1 |
| Lé, CT | 1 |
| Igra, J | 1 |
| Ouellette, EM | 1 |
| Wiszczor-Adamczyk, B | 1 |
| Koślacz-Folga, A | 1 |
| Lombroso, CT | 1 |
| Waterbury, LD | 1 |
| Pearce, LA | 1 |
| Trojaborg, W | 1 |
| Shaywitz, BA | 1 |
| Abdalla, RE | 1 |
| Iskander, S | 1 |
| Haseeb, MA | 1 |
3 reviews available for phenobarbital and Central Nervous System Disease
| Article | Year |
|---|---|
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Ep | 1991 |
The child who convulses with fever.
Topics: Age Factors; Analgesics; Brain Injuries; Central Nervous System Diseases; Child; Child Behavior; Chi | 1974 |
The treatment of status epilepticus.
Topics: Anti-Bacterial Agents; Anticonvulsants; Barbiturates; Brain Edema; Central Nervous System Diseases; | 1974 |
9 other studies available for phenobarbital and Central Nervous System Disease
| Article | Year |
|---|---|
Screening analysis for medicinal drugs and drugs of abuse in whole blood using ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOF-MS)--toxicological findings in cases of alleged sexual assault.
Topics: Adolescent; Adult; Benzodiazepines; Central Nervous System Diseases; Chromatography, Liquid; Crime V | 2012 |
AN UNUSUAL REACTION TO COMBINED LIBRIUM-BARBITURATE THERAPY.
Topics: Barbiturates; Central Nervous System Diseases; Chlordiazepoxide; Nystagmus, Pathologic; Phenobarbita | 1964 |
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brai | 1964 |
Shifting CNS symptoms in a chronic alcoholic.
Topics: Adult; Alcoholism; Central Nervous System Diseases; Cysticercosis; Dexamethasone; Humans; Male; Phen | 1985 |
Results of treatment and clinico-electroencephalographic evolution of infantile spasms.
Topics: Adrenocorticotropic Hormone; Birth Injuries; Central Nervous System Diseases; Child, Preschool; Elec | 1969 |
Separation and identification of neutral and acidic metabolites in cerebrospinal fluid.
Topics: Biogenic Amines; Brain; Central Nervous System Diseases; Cerebrospinal Fluid; Chromatography, Gas; C | 1972 |
Focal spike discharges in children, a longitudinal study.
Topics: Adolescent; Aging; Central Nervous System Diseases; Cerebral Palsy; Cerebral Ventriculography; Child | 1966 |
Extreme elevations of cerebrospinal fluid protein. Association with hypernatremic dehydration.
Topics: Blood Proteins; Blood-Brain Barrier; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; | 1970 |
Further observations on the use of ambilhar in the treatment of schistosomiasis mansoni in the Sudan.
Topics: Adolescent; Adult; Anthelmintics; Central Nervous System Diseases; Child; Drug Hypersensitivity; Fec | 1968 |