Page last updated: 2024-11-02

phenobarbital and Cataract

phenobarbital has been researched along with Cataract in 9 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen can be enzymatically bioactivated, which may play a role in cataractogenesis."7.67Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits. ( Avaria, M; Basu, PK; Lubek, BM; Wells, PG, 1988)
"Cataracts developed in two young adults who were receiving prolonged antiepileptic treatment with phenobarbital sodium and phenytoin sodium."7.66Presenile cataracts in phenytoin-treated epileptic patients. ( Bar, S; Feller, N; Savir, H, 1983)
"Acetaminophen can be enzymatically bioactivated, which may play a role in cataractogenesis."3.67Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits. ( Avaria, M; Basu, PK; Lubek, BM; Wells, PG, 1988)
"Cataracts developed in two young adults who were receiving prolonged antiepileptic treatment with phenobarbital sodium and phenytoin sodium."3.66Presenile cataracts in phenytoin-treated epileptic patients. ( Bar, S; Feller, N; Savir, H, 1983)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BAWA, YS1
GUPTA, PD1
GOEL, BG1
CESA, R1
MARTINELLI, G1
BHATNAGAR, BS1
DUNDAS, JB1
Savir, H2
Bar, S2
Feller, N2
Shichi, H1
Tanaka, M1
Jensen, NM1
Nebert, DW1
Lubek, BM1
Avaria, M1
Basu, PK1
Wells, PG1
Edwards, A1
Gupta, JD1
Harley, JD1

Other Studies

9 other studies available for phenobarbital and Cataract

ArticleYear
CASE REPORTS. COMPLETE HEART BLOCK IN MARFAN'S SYNDROME.
    British heart journal, 1964, Volume: 26

    Topics: Adams-Stokes Syndrome; Arachnodactyly; Atrioventricular Block; Cataract; Electrocardiography; Ephedr

1964
[THE USE OF CURARE IN CATARACT SURGERY. CLINICO-STATISTICAL CONTRIBUTION].
    Annali di ottalmologia e clinica oculistica, 1963, Volume: 89

    Topics: Anesthesia; Anesthesiology; Cataract; Cataract Extraction; Chlorpromazine; Curare; Hibernation; Huma

1963
INTRA-OCULAR PRESSURE IN CATARACT SURGERY.
    Indian journal of medical sciences, 1964, Volume: 18

    Topics: Cataract; Cataract Extraction; Chlorpromazine; Humans; Intraocular Pressure; Phenobarbital; Preopera

1964
LOWE'S SYNDROME.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Chi

1964
Presenile cataracts in hydantoin-treated epileptic patients.
    Metabolic, pediatric, and systemic ophthalmology, 1983, Volume: 7, Issue:3

    Topics: Adult; Animals; Cataract; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Rats

1983
Presenile cataracts in phenytoin-treated epileptic patients.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1983, Volume: 101, Issue:3

    Topics: Adult; Aging; Animals; Cataract; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Rodentia

1983
Genetic differences in cataract and other ocular abnormalities induced by paracetamol and naphthalene.
    Pharmacology, 1980, Volume: 20, Issue:5

    Topics: Acetaminophen; Administration, Oral; Animals; Cataract; Cytochrome P-450 Enzyme System; Enzyme Induc

1980
Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1988, Volume: 10, Issue:4

    Topics: Acetaminophen; Animals; Cataract; Chemical and Drug Induced Liver Injury; Male; Methylcholanthrene;

1988
Photomicrographic evaluation of drug-induced cataracts in cultured embryonic chick lens.
    Experimental eye research, 1973, Volume: 15, Issue:4

    Topics: Animals; Cataract; Chick Embryo; Chloroquine; Culture Media; Culture Techniques; Hydroquinones; Lens

1973