phenobarbital has been researched along with Cat Diseases in 31 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital (PB) q12h is the most common treatment recommendation for cats with recurrent epileptic seizures." | 8.31 | Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy. ( De Decker, S; Mojarradi, A; Van Meervenne, S, 2023) |
| "To determine the percentage of cats with a phenobarbital (PB) concentration between 15 and 45 μg/mL that had a ≥ 50% reduction in the number of seizures and to investigate applicability of the 2011 International League Against Epilepsy (ILAE) classification system in cats." | 7.80 | Evaluation of therapeutic phenobarbital concentrations and application of a classification system for seizures in cats: 30 cases (2004-2013). ( Barnes Heller, HL; Finnerty, KE; Giovanella, CJ; Lau, VW; Mercier, MN; Rylander, H, 2014) |
| "To assess pharmacokinetics, efficacy, and tolerability of oral levetiracetam administered as an adjunct to phenobarbital treatment in cats with poorly controlled suspected idiopathic epilepsy." | 7.74 | Levetiracetam as an adjunct to phenobarbital treatment in cats with suspected idiopathic epilepsy. ( Bailey, KS; Barone, G; Boothe, DM; Dewey, CW; Kortz, GD, 2008) |
| "Seizures are a common cause of neurologic disease, and phenobarbital (PB) is the most commonly used antiepileptic drug." | 5.20 | Therapeutic serum phenobarbital concentrations obtained using chronic transdermal administration of phenobarbital in healthy cats. ( Barnes Heller, HL; Delamaide Gasper, JA; Robertson, M; Trepanier, LA, 2015) |
| "Phenobarbital (PB) q12h is the most common treatment recommendation for cats with recurrent epileptic seizures." | 4.31 | Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy. ( De Decker, S; Mojarradi, A; Van Meervenne, S, 2023) |
| "Phenobarbital (PB) is the most common antiseizure drug (ASD) used for the management of feline epilepsy." | 4.12 | Evaluation of the effect of phenobarbital administration on the biochemistry profile, with a focus on serum liver values, in epileptic cats. ( Bhatti, SF; Broeckx, BJ; Charalambous, M; Cornelis, I; Eisl-Glantschnigg, U; Hermans, M; Neßler, J; Paepe, D; Pakozdy, A; Serrano, G; Van Ham, L; Van Meervenne, SA, 2022) |
| "To determine the percentage of cats with a phenobarbital (PB) concentration between 15 and 45 μg/mL that had a ≥ 50% reduction in the number of seizures and to investigate applicability of the 2011 International League Against Epilepsy (ILAE) classification system in cats." | 3.80 | Evaluation of therapeutic phenobarbital concentrations and application of a classification system for seizures in cats: 30 cases (2004-2013). ( Barnes Heller, HL; Finnerty, KE; Giovanella, CJ; Lau, VW; Mercier, MN; Rylander, H, 2014) |
| "To assess pharmacokinetics, efficacy, and tolerability of oral levetiracetam administered as an adjunct to phenobarbital treatment in cats with poorly controlled suspected idiopathic epilepsy." | 3.74 | Levetiracetam as an adjunct to phenobarbital treatment in cats with suspected idiopathic epilepsy. ( Bailey, KS; Barone, G; Boothe, DM; Dewey, CW; Kortz, GD, 2008) |
| " Cats that were having cluster seizures or status epilepticus at the time of admission were treated orally with phenobarbital and with constant IV administration of diazepam." | 3.69 | Clinical management and outcome of cats with seizure disorders: 30 cases (1991-1993). ( McDonell, W; Parent, JM; Quesnel, AD, 1997) |
| "Oral phenobarbital (PO-PB) was administered for weeks 1-14 (median starting dosage of 3." | 2.90 | Prospective crossover clinical trial comparing transdermal with oral phenobarbital administration in epileptic cats. ( Barnes Heller, HL; Mei, C; Robertson, M; Trepanier, LA, 2019) |
| "Idiopathic epilepsy is the most common brain disease in dogs and also occurs in cats." | 2.46 | Idiopathic epilepsy in dogs and cats. ( Thomas, WB, 2010) |
| "Idiopathic epilepsy is one of the most common and treatable neurologic diseases of small animals." | 2.40 | Idiopathic epilepsy. ( Knowles, K, 1998) |
| "Successful treatment of seizure disorders in small animals requires proper patient assessment, understanding the principles of antiepileptic drug (AED) therapy, designing a strategy for pharmacotherapy, and plans for emergency treatment." | 2.40 | Antiepileptic drug therapy. ( Podell, M, 1998) |
| "The study objective was to investigate the prevalence and clinical characteristics of phenobarbitone-associated adverse effects in epileptic cats." | 1.62 | Prevalence and clinical characteristics of phenobarbitone-associated adverse effects in epileptic cats. ( Corsini, G; De Risio, L; Gutierrez-Quintana, R; Marsh, O; Van Dijk, J, 2021) |
| "Anamnestic data included a generalised seizure disorder and phenobarbital treatment started one month before presentation." | 1.48 | Pseudolymphoma in a cat on phenobarbital treatment. ( Lieser, J; Schwedes, CS, 2018) |
| "A cat with a history of seizures and clinical suspicion of forebrain disorder underwent a brain magnetic resonance imaging." | 1.35 | Toxoplasma gondii brain granuloma in a cat: diagnosis using cytology from an intraoperative sample and sequential magnetic resonance imaging. ( Baroni, M; De Lorenzi, D; Falzone, C; Mandara, MT, 2008) |
| "To establish a dosing regimen for potassium bromide and evaluate use of bromide to treat spontaneous seizures in cats." | 1.31 | Disposition and clinical use of bromide in cats. ( Boothe, DM; Couch, P; George, KL, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Mojarradi, A | 1 |
| De Decker, S | 1 |
| Van Meervenne, S | 1 |
| Sohn, SJ | 1 |
| Jeung, SY | 1 |
| Chae, HK | 1 |
| Cho, HS | 1 |
| An, JH | 1 |
| Li, Q | 1 |
| Song, WJ | 1 |
| Youn, HY | 1 |
| Marsh, O | 1 |
| Corsini, G | 1 |
| Van Dijk, J | 1 |
| Gutierrez-Quintana, R | 1 |
| De Risio, L | 1 |
| Hermans, M | 1 |
| Charalambous, M | 1 |
| Pakozdy, A | 1 |
| Eisl-Glantschnigg, U | 1 |
| Neßler, J | 1 |
| Van Meervenne, SA | 1 |
| Serrano, G | 1 |
| Cornelis, I | 1 |
| Van Ham, L | 1 |
| Paepe, D | 1 |
| Broeckx, BJ | 1 |
| Bhatti, SF | 1 |
| Lieser, J | 1 |
| Schwedes, CS | 1 |
| Barnes Heller, H | 1 |
| Barnes Heller, HL | 3 |
| Trepanier, LA | 2 |
| Robertson, M | 2 |
| Mei, C | 1 |
| de Bairros, AV | 1 |
| Dias, D | 1 |
| Bezerra, A | 1 |
| Wagner, R | 1 |
| Klein, B | 1 |
| Kommers, G | 1 |
| Stefanon, E | 1 |
| Miguel Pego, A | 1 |
| Finnerty, KE | 1 |
| Mercier, MN | 1 |
| Giovanella, CJ | 1 |
| Lau, VW | 1 |
| Rylander, H | 1 |
| Cuff, DE | 1 |
| Bush, WW | 1 |
| Stecker, MM | 1 |
| Williams, DC | 1 |
| Delamaide Gasper, JA | 1 |
| Song, RB | 1 |
| Glass, EN | 1 |
| Kent, M | 1 |
| Castro, FA | 1 |
| deLahunta, A | 1 |
| Kluger, EK | 1 |
| Malik, R | 1 |
| Govendir, M | 1 |
| Thomas, WB | 1 |
| Boydell, P | 2 |
| Baho, MJ | 1 |
| Hostutler, R | 1 |
| Fenner, W | 1 |
| Corn, S | 1 |
| Berthiaume, DR | 1 |
| Kline, KL | 1 |
| Boothe, DM | 2 |
| George, KL | 1 |
| Couch, P | 1 |
| Dodman, NH | 1 |
| Billingham, EA | 1 |
| Moon-Fanelli, AA | 1 |
| Falzone, C | 1 |
| Baroni, M | 1 |
| De Lorenzi, D | 1 |
| Mandara, MT | 1 |
| Bailey, KS | 1 |
| Dewey, CW | 2 |
| Barone, G | 1 |
| Kortz, GD | 1 |
| Holliday, TA | 1 |
| Hendricks, JC | 1 |
| Morrison, AR | 1 |
| Farnbach, GL | 1 |
| Steinberg, SA | 1 |
| Mann, G | 1 |
| Bunch, SE | 1 |
| Quesnel, AD | 1 |
| Parent, JM | 1 |
| McDonell, W | 1 |
| Swanepoel, N | 1 |
| Lee, E | 1 |
| Stein, DJ | 1 |
| Knowles, K | 1 |
| Podell, M | 1 |
| Pike, R | 1 |
| Crossley, D | 1 |
| Ducote, JM | 1 |
| Coates, JR | 1 |
| Kennis, RA | 1 |
| Frey, HH | 1 |
6 reviews available for phenobarbital and Cat Diseases
| Article | Year |
|---|---|
Feline Epilepsy.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Epilepsy; Levetiracetam; Phenobarbital; Piracetam; Pro | 2018 |
Idiopathic epilepsy in dogs and cats.
Topics: Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Dog Diseases; Dogs; Dose-Response Relationsh | 2010 |
Seizure disorders.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Dog Diseases; Dogs; Epilepsy; Mephob | 1980 |
Hepatotoxicity associated with pharmacologic agents in dogs and cats.
Topics: Animals; Anthelmintics; Benzimidazoles; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; | 1993 |
Idiopathic epilepsy.
Topics: Age Factors; Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Diagnosis, Differential; Dog Di | 1998 |
Antiepileptic drug therapy.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Cyclohexanecarboxylic Acid | 1998 |
2 trials available for phenobarbital and Cat Diseases
| Article | Year |
|---|---|
Prospective crossover clinical trial comparing transdermal with oral phenobarbital administration in epileptic cats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Anticonvulsants; Cat Diseases; Cats; Cross | 2019 |
Therapeutic serum phenobarbital concentrations obtained using chronic transdermal administration of phenobarbital in healthy cats.
Topics: Administration, Cutaneous; Animals; Anticonvulsants; Biological Availability; Cat Diseases; Cats; Ph | 2015 |
23 other studies available for phenobarbital and Cat Diseases
| Article | Year |
|---|---|
Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy.
Topics: Animals; Cat Diseases; Cats; Epilepsy; Phenobarbital; Prospective Studies; Quality of Life; Retrospe | 2023 |
Phenobarbital-induced anticonvulsant hypersensitivity syndrome in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Drug Hypersensitivity; Epilepsy; Fever; Lymphadenopath | 2019 |
Prevalence and clinical characteristics of phenobarbitone-associated adverse effects in epileptic cats.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Epilepsy; Phenobarbital; Prevalence | 2021 |
Evaluation of the effect of phenobarbital administration on the biochemistry profile, with a focus on serum liver values, in epileptic cats.
Topics: Alanine Transaminase; Animals; Anticonvulsants; Cat Diseases; Cats; Dog Diseases; Dogs; Epilepsy; Fe | 2022 |
Pseudolymphoma in a cat on phenobarbital treatment.
Topics: Animals; Cat Diseases; Cats; Epilepsy; Female; Lymphadenopathy; Phenobarbital; Pseudolymphoma | 2018 |
An analytical strategy for the identification of carbamates, toxic alkaloids, phenobarbital and warfarin in stomach contents from suspected poisoned animals by thin-layer chromatography/ultraviolet detection.
Topics: Alkaloids; Animals; Carbamates; Cat Diseases; Cats; Chromatography, Thin Layer; Dog Diseases; Dogs; | 2019 |
Evaluation of therapeutic phenobarbital concentrations and application of a classification system for seizures in cats: 30 cases (2004-2013).
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Phenobarbital; Seizures | 2014 |
Use of continuous electroencephalography for diagnosis and monitoring of treatment of nonconvulsive status epilepticus in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Electroencephalography; Male; Phenobarbital; Status Ep | 2014 |
Magnetic resonance imaging and computed tomography findings of Dyke-Davidoff-Masson-like syndrome in a cat.
Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Brain Injuries; Cat Diseases; Cats; Female; Magneti | 2015 |
Veterinarians' preferences for anticonvulsant drugs for treating seizure disorders in dogs and cats.
Topics: Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Cross-Sectional Studies; Dog Diseases; Dogs; | 2009 |
Rub epilepsy in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Epilepsy, Reflex; Forelimb; Grooming; Male; Phenobarbi | 2010 |
Suspected phenobarbital-induced pseudolymphoma in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Epilepsy; Female; Levetiracetam; Phenobarbital; Pirace | 2011 |
What is your neurologic diagnosis? C gattii infection.
Topics: Animals; Anticonvulsants; Antifungal Agents; Cat Diseases; Cats; Central Nervous System Infections; | 2012 |
Disposition and clinical use of bromide in cats.
Topics: Administration, Oral; Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Dose-Response Relation | 2002 |
Animal behavior case of the month. Behavioral seizures.
Topics: Aggression; Analgesics, Opioid; Animals; Anticonvulsants; Behavior, Animal; Butorphanol; Cat Disease | 2005 |
Toxoplasma gondii brain granuloma in a cat: diagnosis using cytology from an intraoperative sample and sequential magnetic resonance imaging.
Topics: Animals; Cat Diseases; Cats; Clindamycin; Fatal Outcome; Granuloma; Magnetic Resonance Imaging; Male | 2008 |
Levetiracetam as an adjunct to phenobarbital treatment in cats with suspected idiopathic epilepsy.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Drug Therapy, Combination; Epilepsies, Partial; Epilep | 2008 |
A disorder of rapid eye movement sleep in a cat.
Topics: Animals; Cat Diseases; Cats; Electromyography; Female; Humans; Motor Activity; Phenobarbital; Sleep | 1981 |
Clinical management and outcome of cats with seizure disorders: 30 cases (1991-1993).
Topics: Administration, Oral; Animals; Anticonvulsants; Cat Diseases; Cats; Dexamethasone; Diazepam; Follow- | 1997 |
Psychogenic alopecia in a cat: response to clomipramine.
Topics: Alopecia; Animals; Cat Diseases; Cats; Clomipramine; Diazepam; Drug Combinations; Glucocorticoids; P | 1998 |
Presumptive sialadenosis in a cat.
Topics: Animals; Cat Diseases; Cats; Excitatory Amino Acid Antagonists; Male; Phenobarbital; Salivary Gland | 2000 |
Suspected hypersensitivity to phenobarbital in a cat.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Diagnosis, Differential; Drug Eruptions; Male; Phenoba | 1999 |
Use of anticonvulsants in small animals.
Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Dog Diseases; Dogs; Epilepsy; Epilepsy, Tonic-Clonic; | 1986 |