phenobarbital has been researched along with Cardiovascular Pregnancy Complications in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma half-lives of amobarbital were determined in newborn children of 10 mothers who had been treated with barbiturates for hypertension in pregnancy for 6 to 42 days prior to delivery." | 7.65 | Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy. ( Clare, RA; Darling, M; Davies, DS; Dollery, CT; Draffan, GH; Hawkins, DF; Krauer, B; Sertel, H; Trudinger, BJ; Williams, FM, 1976) |
| "Plasma half-lives of amobarbital were determined in newborn children of 10 mothers who had been treated with barbiturates for hypertension in pregnancy for 6 to 42 days prior to delivery." | 3.65 | Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy. ( Clare, RA; Darling, M; Davies, DS; Dollery, CT; Draffan, GH; Hawkins, DF; Krauer, B; Sertel, H; Trudinger, BJ; Williams, FM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basalamah, AH | 1 |
| Hardy, MJ | 1 |
| Mathews, DD | 1 |
| Diehl, LW | 1 |
| Draffan, GH | 1 |
| Dollery, CT | 1 |
| Davies, DS | 1 |
| Krauer, B | 1 |
| Williams, FM | 1 |
| Clare, RA | 1 |
| Trudinger, BJ | 1 |
| Darling, M | 1 |
| Sertel, H | 1 |
| Hawkins, DF | 1 |
| Kuban, KC | 1 |
| Leviton, A | 1 |
| Pagano, M | 1 |
| Fenton, T | 1 |
| Strassfeld, R | 1 |
| Wolff, M | 1 |
| Hoffmann-Traeger, A | 1 |
| Peiker, G | 1 |
| Glöckner, R | 1 |
| Wittmann, I | 1 |
| Balogh, A | 1 |
| Henschel, L | 1 |
| Littler, WA | 1 |
| Lindheimer, MD | 1 |
| Roux, J | 1 |
1 trial available for phenobarbital and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
A randomized controlled trial of bed rest and sedation or normal activity and non-sedation in the management of non-albuminuric hypertension in late pregnancy.
Topics: Adult; Bed Rest; Clinical Trials as Topic; Female; Hospitalization; Humans; Hypertension; Hypnotics | 1977 |
7 other studies available for phenobarbital and Cardiovascular Pregnancy Complications
| Article | Year |
|---|---|
Phenobarbitone and serum unconjugated oestriol concentrations in four pregnant women with hypertension.
Topics: Estriol; Female; Humans; Hypertension; Phenobarbital; Pregnancy; Pregnancy Complications, Cardiovasc | 1980 |
[Anticonvulsants and simultaneous medication - a problem in pregnancy (author's transl)].
Topics: Adult; Anticonvulsants; Antiemetics; Dihydroergotamine; Drug Combinations; Drug Interactions; Drug T | 1977 |
Maternal and neonatal elimination of amobarbital after treatment of the mother with barbiturates during late pregnancy.
Topics: Adult; Amobarbital; Barbiturates; Female; Half-Life; Humans; Hypertension; Infant, Newborn; Kinetics | 1976 |
Maternal toxemia is associated with reduced incidence of germinal matrix hemorrhage in premature babies.
Topics: Cerebral Hemorrhage; Cerebral Palsy; Double-Blind Method; Female; Humans; Hypertension; Infant, Newb | 1992 |
The influence of phenobarbital on the pharmacokinetics of propranolol in pregnancy.
Topics: Drug Interactions; Female; Half-Life; Humans; Hypertension; Phenobarbital; Pregnancy; Pregnancy Comp | 1987 |
Successful pregnancy in a patient with Ebstein's anomaly.
Topics: Adult; Cardiac Catheterization; Ebstein Anomaly; Electrocardiography; Epilepsies, Partial; Female; H | 1970 |
Role of posture in sodium, water, and potassium homeostasis of an abnormal pregnancy.
Topics: Adolescent; Aminohippuric Acids; Blood Pressure; Creatinine; Diet Therapy; Diuresis; Female; Glomeru | 1970 |