phenobarbital has been researched along with Cardiac Failure in 9 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 7.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 3.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| " Based on the available data it seems that one may postulate the following conclusions: (1) that the distribution factors as well as changes in drug elimination capacities seem to play a role, perhaps with differing relative importance, during each of the maturational periods; (2) that the physicochemical properties of a drug and its dosage, as well as changes in the volume of distribution in children, in the course of certain disease states may have a significant effect on kinetics of drug disposition in the body; (3) that systemic clearance, a model independent parameter, rather than elimination half-life, a hybrid pharmacokinetic parameter, more accurately reflects elimination of some drugs from the body; (4) that each drug and every clinical situation may require the evaluation of the direct effect on pharmacokinetic processes, since general principles may not always apply; (5) that drug disposition studies should also be performed, if possible, on patients under actual clinical situations and receiving the usual therapeutic regime, and (6) that the half-life of colistin is independent of postnatal age which should serve as a warning not to generalize about drug excretion in the young infant." | 2.37 | Clinical pharmacokinetics of changes in drug elimination in children. ( Prandota, J, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DE MICHELI, E | 1 |
| PARENTI, B | 1 |
| FINEBERG, SK | 1 |
| MACKENZIE, GJ | 1 |
| PASCUAL, S | 1 |
| Wimmer, H | 1 |
| Spesshardt, K | 1 |
| Risler, T | 1 |
| Seipel, L | 1 |
| Miano, A | 1 |
| Casadei, G | 1 |
| Biasini, G | 1 |
| Arima, M | 1 |
| Kanoh, T | 1 |
| Yamasaki, A | 1 |
| Matsuda, S | 1 |
| Kasuya, H | 1 |
| Sunayama, S | 1 |
| Kawai, S | 1 |
| Okada, R | 1 |
| Prandota, J | 1 |
| Aryanpur, I | 1 |
| Farhoudi, A | 1 |
| Zangeneh, F | 1 |
1 review available for phenobarbital and Cardiac Failure
| Article | Year |
|---|---|
Clinical pharmacokinetics of changes in drug elimination in children.
Topics: Adult; Anti-Bacterial Agents; Brain Injuries; Child; Child, Preschool; Colistin; Cystic Fibrosis; Di | 1985 |
8 other studies available for phenobarbital and Cardiac Failure
| Article | Year |
|---|---|
[The combination of meprobamate and phenylethylmalonylurea in therapy].
Topics: Arteriosclerosis; Heart Failure; Humans; Hypertension; Hyperthyroidism; Meprobamate; Myocardial Infa | 1963 |
MASSIVE OBESITY AND WATER RETENTION.
Topics: Diet, Reducing; Diuretics; Edema; Heart Failure; Humans; Obesity; Phenmetrazine; Phenobarbital | 1964 |
PAROXYSMAL VENTRICULAR TACHYCARDIA.
Topics: Coronary Disease; Diagnosis; Digitalis Glycosides; Electrocardiography; Heart Failure; Hydrocortison | 1964 |
[The treatment of heart diseases from various causes with the combination preparation Spasmo-Guttacor].
Topics: Coronary Disease; Heart Failure; Humans; Papaverine; Phenobarbital; Plants, Medicinal; Quinidine | 1966 |
[Controlled digitalis therapy].
Topics: Cholestyramine Resin; Digitalis Glycosides; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Dr | 1983 |
Cardiac failure in pseudohypoparathyroidism.
Topics: Anticonvulsants; Child, Preschool; Heart Failure; Humans; Male; Phenobarbital; Pseudohypoparathyroid | 1981 |
Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital.
Topics: Adult; Drug Eruptions; Eosinophilia; Heart Failure; Humans; Hypnotics and Sedatives; Male; Myocardit | 1998 |
Congestive heart failure secondary to idiopathic hypoparathyroidism.
Topics: Adolescent; Calcium; Diagnostic Errors; Digoxin; Electrocardiography; Electroencephalography; Epilep | 1974 |