phenobarbital has been researched along with Carcinoma 256, Walker in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic parameters and enzyme kinetic data both in normal and in tumor-bearing animals will be presented." | 1.26 | Importance of pharmacokinetic studies on cyclophosphamide (NSC-26271) in understanding its cytotoxic effect. ( Bartosek, I; Colombo, T; Donelli, MG; Guaitani, A; Martini, A; Modica, R; Pacciarini, MA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KATO, R | 3 |
| FRONTINO, G | 1 |
| VASSANELLI, P | 1 |
| Rapoport, EA | 1 |
| Konikova, AS | 1 |
| Donelli, MG | 1 |
| Bartosek, I | 1 |
| Guaitani, A | 1 |
| Martini, A | 1 |
| Colombo, T | 1 |
| Pacciarini, MA | 1 |
| Modica, R | 1 |
| Takanaka, A | 2 |
| Takahashi, A | 1 |
| Onoda, K | 1 |
| Sladek, NE | 2 |
| Kovacs, JD | 1 |
| Khandekar, B | 1 |
| Tuchweber, B | 1 |
| Oshima, T | 1 |
8 other studies available for phenobarbital and Carcinoma 256, Walker
| Article | Year |
|---|---|
Phenobarbital markedly increases liver weight in Walker carcinosarcoma bearing rats.
Topics: Animals; Carcinoma; Carcinoma 256, Walker; Carcinosarcoma; Liver; Phenobarbital; Rats | 1963 |
Radiotracer studies on protein metabolism in different focuses of growth in vivo.
Topics: Amino Acids; Animals; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Hepatectomy; Liver; Liver Neo | 1979 |
Importance of pharmacokinetic studies on cyclophosphamide (NSC-26271) in understanding its cytotoxic effect.
Topics: Animals; Carcinoma 256, Walker; Chloral Hydrate; Cyclophosphamide; Disulfiram; Drug Interactions; Gl | 1976 |
Drug metabolism in tumor-bearing rats. I. Activities of NADPH-linked electron transport and drug-metabolizing enzyme systems in liver microsomes of tumor-bearing rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Barbiturates; Body Weight; Carcinoma 256, Walker; Carisopro | 1968 |
Bioassay and relative cytotoxic potency of cyclophosphamide metabolites generated in vitro and in vivo.
Topics: Acrolein; Animals; Biological Assay; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Cyclophosph | 1973 |
Therapeutic efficacy of cyclophosphamide as a function of its metabolism.
Topics: Acetamides; Animals; Carcinoma 256, Walker; Cobalt; Cyclophosphamide; Cytochromes; Female; In Vitro | 1972 |
Effect of phenobarbital and pregnenolone-16 -carbonitrile on the toxic and antineoplastic action of cyclophosphamide.
Topics: Animals; Biotransformation; Carcinoma 256, Walker; Cyclophosphamide; Drug Interactions; Female; Nitr | 1971 |
Drug metabolism in tumor-bearing rats. II. In vivo metabolisms and effects of drugs in tumor-bearing rats.
Topics: Anesthesia; Animals; Carcinoma 256, Walker; Carisoprodol; Cholinesterase Inhibitors; Female; Injecti | 1968 |