Page last updated: 2024-11-02

phenobarbital and Cancer of Prostate

phenobarbital has been researched along with Cancer of Prostate in 8 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ellfolk, M1
Norlin, M1
Gyllensten, K1
Wikvall, K1
Baum, N1
Pollard, M1
Luckert, PH1
Scheu, J1
Smith, JA1
Pescatore, P1
Hammel, P1
Durand, F1
Bertheau, P1
Bernuau, J1
Huc, D1
Gerbal, JL1
Degott, C1
Benhamou, JP1
El-Alfy, M1
Pelletier, G1
Hermo, LS1
Labrie, F1
Cooper, TP1
Barham, RE1
Ansell, JS1
Oesch, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women.[NCT00248989]Phase 3150 participants (Actual)Interventional2004-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for phenobarbital and Cancer of Prostate

ArticleYear
Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
    Xenobiotica; the fate of foreign compounds in biological systems, 1973, Volume: 3, Issue:5

    Topics: Animals; Antimetabolites; Benz(a)Anthracenes; Binding Sites; Carcinogens; Enzyme Induction; Ethers,

1973

Trials

1 trial available for phenobarbital and Cancer of Prostate

ArticleYear
A prospective comparison of treatments for symptomatic hot flushes following endocrine therapy for carcinoma of the prostate.
    The Journal of urology, 1994, Volume: 152, Issue:1

    Topics: Aged; Androgen Antagonists; Clonidine; Diethylstilbestrol; Ergotamine; Flushing; Gonadotropin-Releas

1994

Other Studies

6 other studies available for phenobarbital and Cancer of Prostate

ArticleYear
Regulation of human vitamin D(3) 25-hydroxylases in dermal fibroblasts and prostate cancer LNCaP cells.
    Molecular pharmacology, 2009, Volume: 75, Issue:6

    Topics: Alkynes; Anti-HIV Agents; Anticonvulsants; Benzoxazines; Calcitriol; Cell Line; Cell Line, Tumor; Ch

2009
How to manage hot flashes in prostate cancer?
    Postgraduate medicine, 2003, Volume: 113, Issue:5

    Topics: Administration, Oral; Antineoplastic Agents, Hormonal; Belladonna Alkaloids; Diethylstilbestrol; Dos

2003
Phenobarbital promotes the development of adenocarcinomas in the accessory sex glands of MNU-inoculated L-W rats.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Abdominal Neoplasms; Adenocarcinoma; Adenoma; Aging; Animals; Carcinogens; Drug Implants; Genital Ne

1995
[Fatal fulminant hepatitis induced by nilutamide (Anandron)].
    Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:6-7

    Topics: Adenocarcinoma; Aged; Androgen Antagonists; Chemical and Drug Induced Liver Injury; Drug Interaction

1993
Unique features of the basal cells of human prostate epithelium.
    Microscopy research and technique, 2000, Dec-01, Volume: 51, Issue:5

    Topics: Animals; Cell Differentiation; Dogs; Epithelial Cells; Humans; Immunohistochemistry; Macaca fascicul

2000
Methylcholanthrene-induced adenocarcinoma of the prostate in rats.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasms, Experimental

1974