phenobarbital has been researched along with Brain Inflammation in 21 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To clarify the effect of levetiracetam (LEV) for acute and chronic seizure control in acute encephalitis with refractory, repetitive partial seizures (AERRPS)." | 7.81 | Effect of levetiracetam in acute encephalitis with refractory, repetitive partial seizures during acute and chronic phase. ( Imamura, A; Maegaki, Y; Maruta, K; Matsunami, K; Narita, A; Nishimura, Y; Ohno, K; Saiki, Y; Saito, Y; Sokota, T; Sugihara, S; Tamasaki, A; Ueda, R, 2015) |
| "After treatment, convulsions were suppressed and daily life continued, but intellectual impairment and high-level dysfunction remained." | 5.43 | High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures. ( Endo, W; Haginoya, K; Kitamura, T; Nishio, T; Numata, Y; Ohura, T; Takayanagi, M; Uchida, T, 2016) |
| "Phenobarbital (PB) was administrated at a very high daily dose up to 80 mg/kg, reaching serum trough level of 250 μg/ml, which was markedly effective to the treatment." | 5.40 | [A case of acute encephalitis with refractory repetitive partial seizures successfully controlled by very-high-dose phenobarbital therapy found in a boy]. ( Aiba, H; Okumura, Y; Watanabe, S, 2014) |
| " Seizures in three patients were stopped after high-dose lidocaine infusion (6-8 mg/kg/h) in the acute stage and three patients were stopped after high dose phenobarbital (serum level 60-80 ug/mL) combined with high-dose oral topiramate (15-20 mg/kg/day)." | 5.35 | Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009) |
| "To clarify the effect of levetiracetam (LEV) for acute and chronic seizure control in acute encephalitis with refractory, repetitive partial seizures (AERRPS)." | 3.81 | Effect of levetiracetam in acute encephalitis with refractory, repetitive partial seizures during acute and chronic phase. ( Imamura, A; Maegaki, Y; Maruta, K; Matsunami, K; Narita, A; Nishimura, Y; Ohno, K; Saiki, Y; Saito, Y; Sokota, T; Sugihara, S; Tamasaki, A; Ueda, R, 2015) |
| " We describe a patient with phenobarbital-induced hypersensitivity syndrome who revealed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with limbic encephalitis during the course of the disease." | 3.74 | Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome. ( Fukuhara, M; Kano, Y; Sakuma, K; Shiohara, T, 2008) |
| "Initially, the prolonged seizures ceased after systemic midazolam treatment and were thought to be fever associated." | 1.51 | Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report. ( Hornei, B; Jacobsen, S; Jenke, AC; Koukou, G; Niendorf, S; Schlump, JU, 2019) |
| "Mild encephalopathy/encephalitis with a reversible splenial (MERS) lesion is a clinic-radiological entity." | 1.46 | Mild encephalopathy/encephalitis with a reversible splenial lesion (MERS): A report of five neonatal cases. ( Baralc, S; Chen, L; Chen, WH; Liu, ZS; Sun, D; Wang, J; Xia, YP, 2017) |
| "After treatment, convulsions were suppressed and daily life continued, but intellectual impairment and high-level dysfunction remained." | 1.43 | High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures. ( Endo, W; Haginoya, K; Kitamura, T; Nishio, T; Numata, Y; Ohura, T; Takayanagi, M; Uchida, T, 2016) |
| "Phenobarbital (PB) was administrated at a very high daily dose up to 80 mg/kg, reaching serum trough level of 250 μg/ml, which was markedly effective to the treatment." | 1.40 | [A case of acute encephalitis with refractory repetitive partial seizures successfully controlled by very-high-dose phenobarbital therapy found in a boy]. ( Aiba, H; Okumura, Y; Watanabe, S, 2014) |
| " Seizures in three patients were stopped after high-dose lidocaine infusion (6-8 mg/kg/h) in the acute stage and three patients were stopped after high dose phenobarbital (serum level 60-80 ug/mL) combined with high-dose oral topiramate (15-20 mg/kg/day)." | 1.35 | Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures. ( Hsia, SH; Lin, JJ; Lin, KL; Wang, HS; Wu, CT, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (57.14) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koukou, G | 1 |
| Niendorf, S | 1 |
| Hornei, B | 1 |
| Schlump, JU | 1 |
| Jenke, AC | 1 |
| Jacobsen, S | 1 |
| Sun, D | 1 |
| Chen, WH | 1 |
| Baralc, S | 1 |
| Wang, J | 1 |
| Liu, ZS | 1 |
| Xia, YP | 1 |
| Chen, L | 1 |
| Ueda, R | 1 |
| Saito, Y | 1 |
| Ohno, K | 1 |
| Maruta, K | 1 |
| Matsunami, K | 1 |
| Saiki, Y | 1 |
| Sokota, T | 1 |
| Sugihara, S | 1 |
| Nishimura, Y | 1 |
| Tamasaki, A | 1 |
| Narita, A | 1 |
| Imamura, A | 1 |
| Maegaki, Y | 1 |
| Watanabe, S | 1 |
| Okumura, Y | 1 |
| Aiba, H | 1 |
| Uchida, T | 1 |
| Takayanagi, M | 1 |
| Kitamura, T | 1 |
| Nishio, T | 1 |
| Numata, Y | 1 |
| Endo, W | 1 |
| Haginoya, K | 1 |
| Ohura, T | 1 |
| Lin, JJ | 1 |
| Lin, KL | 1 |
| Wang, HS | 1 |
| Hsia, SH | 1 |
| Wu, CT | 1 |
| ONUAGULUCHI, G | 1 |
| JANZ, D | 1 |
| KAUTZ, G | 1 |
| CHAROKOPOS, S | 1 |
| SAKELLARIDES, N | 1 |
| ALLAMANES, I | 1 |
| STAURIANOS, N | 1 |
| BAIRD, HW | 1 |
| BAUER, AR | 1 |
| HOWARD, PJ | 1 |
| Sakuma, K | 1 |
| Kano, Y | 1 |
| Fukuhara, M | 1 |
| Shiohara, T | 1 |
| Andréasson, S | 1 |
| Larsson, LE | 1 |
| Bergström, T | 1 |
| Alestig, K | 1 |
| Salmoiraghi, L | 1 |
| Carabellese, G | 1 |
| Jones, CM | 1 |
| Dunn, HG | 1 |
| Thomas, EE | 1 |
| Cone, RW | 1 |
| Weber, JM | 1 |
| Koie, H | 1 |
| Kurotobi, EN | 1 |
| Sakai, T | 1 |
| McNaughton, FL | 1 |
| Rasmussen, T | 1 |
| Daniel, DG | 1 |
| Rabin, PL | 1 |
| Gregoriades, AD | 1 |
| Gascon, G | 1 |
| Barlow, C | 1 |
| Baska, RE | 1 |
| Kepes, J | 1 |
| Ziegler, DK | 1 |
21 other studies available for phenobarbital and Brain Inflammation
| Article | Year |
|---|---|
Human astrovirus infection associated with encephalitis in an immunocompetent child: a case report.
Topics: Anticonvulsants; Astroviridae Infections; Diarrhea; Encephalitis; Feces; Female; Gastroenteritis; Hu | 2019 |
Mild encephalopathy/encephalitis with a reversible splenial lesion (MERS): A report of five neonatal cases.
Topics: Brain Diseases; Cefoperazone; Corpus Callosum; Electroencephalography; Encephalitis; Hospitalization | 2017 |
Effect of levetiracetam in acute encephalitis with refractory, repetitive partial seizures during acute and chronic phase.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Bromides; Child; Chronic Disease; Encephalitis; F | 2015 |
[A case of acute encephalitis with refractory repetitive partial seizures successfully controlled by very-high-dose phenobarbital therapy found in a boy].
Topics: Acute Disease; Child; Encephalitis; Humans; Male; Phenobarbital; Seizures; Status Epilepticus; Treat | 2014 |
High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures.
Topics: Acute Disease; Anticonvulsants; Barbiturates; Child; Dose-Response Relationship, Drug; Drug Administ | 2016 |
Effect of topiramate, in combination with lidocaine, and phenobarbital, in acute encephalitis with refractory repetitive partial seizures.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography | 2009 |
Drug therapy in the crises of postencephalitic parkinsonism.
Topics: Amobarbital; Encephalitis; Encephalitis, Arbovirus; Humans; Parkinson Disease; Parkinson Disease, Po | 1961 |
[ETIOLOGY AND THERAPY OF STATUS EPILEPTICUS].
Topics: Abortion, Septic; Anticonvulsants; Birth Injuries; Brain Injuries; Brain Neoplasms; Chloral Hydrate; | 1963 |
[EPILEPSY IN INFANCY AND CHILDHOOD. REMARKS ON 360 PERSONAL CASES].
Topics: Adolescent; Adrenocorticotropic Hormone; Birth Injuries; Brain; Brain Damage, Chronic; Brain Disease | 1963 |
CONVULSIONS IN INFANCY AND CHILDHOOD.
Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy, | 1963 |
ENCEPHALITIS FOLLOWING MODIFIED MEASLES.
Topics: Child; Diphenhydramine; Drug Therapy; Electroencephalography; Encephalitis; Encephalomyelitis, Acute | 1964 |
Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome.
Topics: Acyclovir; Aged; Anticonvulsants; Antiviral Agents; Coma; Drug Hypersensitivity; Encephalitis; Epile | 2008 |
Severe acute encephalitis--improved outcome after barbiturate treatment?
Topics: Acyclovir; Adult; Chickenpox; Child; Combined Modality Therapy; Dexamethasone; Encephalitis; Female; | 1984 |
[Our experience with intensive therapy of some cases of infantile encephalitis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Coma; Dexamethasone; Encephalitis; | 1981 |
Acute encephalopathy and status epilepticus associated with human herpes virus 6 infection.
Topics: Comorbidity; Electroencephalography; Encephalitis; Exanthema Subitum; Fever; Herpesviridae Infection | 1994 |
Double-chambered right ventricle in a dog.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Disea | 2000 |
Criteria for selection of patients for neurosurgical treatment.
Topics: Adolescent; Age Factors; Child; Electroencephalography; Encephalitis; Epilepsies, Partial; Epilepsy; | 1975 |
Disguises of delirium.
Topics: Adult; Aged; Brain Diseases; Delirium; Diagnosis, Differential; Drug-Related Side Effects and Advers | 1985 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalog | 1972 |
Juvenile migraine, presenting as an acute confusional state.
Topics: Adolescent; Child; Diagnosis, Differential; Electroencephalography; Encephalitis; Epilepsy, Absence; | 1970 |
Subacute encephalitis. A case report.
Topics: Adolescent; Brain; Diagnosis, Differential; Diazepam; Electroencephalography; Electromyography; Ence | 1967 |