phenobarbital has been researched along with Brain Hemorrhage, Cerebral in 100 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationships among serum bilirubin concentration on days 5 and 7, birth weight, the presence of intraventricular hemorrhage, and the receipt of phenobarbital were examined in a group of 232 newborns weighing less than 1,751 g who were intubated, mechanically ventilated by 12 hours after birth, and whose parents had given permission for a randomized trial of phenobarbital prophylaxis of intraventricular hemorrhage." | 9.06 | Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies. ( Brown, ER; Epstein, MF; Kuban, KC; Leviton, A; Meltzer, C; Pagano, M; Skouteli, HN; Sullivan, KF, 1988) |
| "Forty-six pregnant women less than 35 weeks of gestation were enrolled in a prospective randomized controlled study evaluating the effects of antenatal phenobarbital on neonatal intracerebral hemorrhage." | 9.06 | Antenatal phenobarbital for the prevention of neonatal intracerebral hemorrhage. ( Bedard, MP; Bhatia, R; Cepeda, EE; Hassan, M; Ilagan, N; Mariona, F; Ostrea, E; Poland, RL; Shankaran, S, 1986) |
| " In this study cerebral blood flow values in steady state and during phenylephrine-induced hypertension with and without phenobarbital pretreatment were measured in newborn beagles." | 7.68 | Phenobarbital and cerebral blood flow during hypertension in the newborn beagle. ( Adham, BI; Donley, DK; Goddard-Finegold, J; Michael, LH, 1990) |
| "The transplacental and elimination pharmacokinetics of phenobarbital administered antenatally was analyzed in both mothers and infants as part of a study evaluating the efficacy of antenatally administered phenobarbital in the prevention of neonatal intracerebral hemorrhage." | 7.67 | Pharmacokinetic basis for antenatal dosing of phenobarbital for the prevention of neonatal intracerebral hemorrhage. ( Cepeda, EE; Ilagan, N; Kauffman, RE; Shankaran, S, 1986) |
| "To determine the effect of phenobarbital sodium therapy and subependymal intraventricular hemorrhage (SEp-IVH) on the theophylline requirement of premature infants suffering with apnea and seizure activity, we compared three groups of patients as follows: group 1, those with apnea of prematurity (ten patients); group 2, those with apnea and SEp-IVH (ten patients); and group 3, those with apnea, SEp-IVH, and seizure activity for which they were receiving phenobarbital therapy (nine patients)." | 7.67 | Phenobarbital increases the theophylline requirement of premature infants being treated for apnea. ( Gottschalk, SK; Kissling, GE; Schuth, CR; Tran, TH; Yazdani, M, 1987) |
| "Phenobarbital sodium (PhS) has been used in anticonvulsant concentrations in premature newborns in attempts to prevent peri- and intraventricular hemorrhages (PIVH)." | 5.29 | Phenobarbital and cerebral blood flow during hypotension in newborn pigs. ( Contant, CF; Goddard-Finegold, J; Martin, CG; Michael, LH; Yamashita, Y, 1993) |
| "The objective of this paper is to determine if phenobarbital exposure during pregnancy affects developmental outcome at age 2 years." | 5.09 | Does perinatal phenobarbital exposure affect developmental outcome at age 2? ( Belden, B; Hoffman, EL; Jones, AM; O'Connor, M; Thorp, JA, 1999) |
| "The relationships among serum bilirubin concentration on days 5 and 7, birth weight, the presence of intraventricular hemorrhage, and the receipt of phenobarbital were examined in a group of 232 newborns weighing less than 1,751 g who were intubated, mechanically ventilated by 12 hours after birth, and whose parents had given permission for a randomized trial of phenobarbital prophylaxis of intraventricular hemorrhage." | 5.06 | Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies. ( Brown, ER; Epstein, MF; Kuban, KC; Leviton, A; Meltzer, C; Pagano, M; Skouteli, HN; Sullivan, KF, 1988) |
| "Forty-six pregnant women less than 35 weeks of gestation were enrolled in a prospective randomized controlled study evaluating the effects of antenatal phenobarbital on neonatal intracerebral hemorrhage." | 5.06 | Antenatal phenobarbital for the prevention of neonatal intracerebral hemorrhage. ( Bedard, MP; Bhatia, R; Cepeda, EE; Hassan, M; Ilagan, N; Mariona, F; Ostrea, E; Poland, RL; Shankaran, S, 1986) |
| " He manifested apnea during the first 12 hours of life." | 3.72 | Temporal lobe hemorrhage in the full-term neonate presenting as apneic seizures. ( Goodkin, HP; Tramonte, JJ, 2004) |
| " In this study cerebral blood flow values in steady state and during phenylephrine-induced hypertension with and without phenobarbital pretreatment were measured in newborn beagles." | 3.68 | Phenobarbital and cerebral blood flow during hypertension in the newborn beagle. ( Adham, BI; Donley, DK; Goddard-Finegold, J; Michael, LH, 1990) |
| "The transplacental and elimination pharmacokinetics of phenobarbital administered antenatally was analyzed in both mothers and infants as part of a study evaluating the efficacy of antenatally administered phenobarbital in the prevention of neonatal intracerebral hemorrhage." | 3.67 | Pharmacokinetic basis for antenatal dosing of phenobarbital for the prevention of neonatal intracerebral hemorrhage. ( Cepeda, EE; Ilagan, N; Kauffman, RE; Shankaran, S, 1986) |
| "To determine the effect of phenobarbital sodium therapy and subependymal intraventricular hemorrhage (SEp-IVH) on the theophylline requirement of premature infants suffering with apnea and seizure activity, we compared three groups of patients as follows: group 1, those with apnea of prematurity (ten patients); group 2, those with apnea and SEp-IVH (ten patients); and group 3, those with apnea, SEp-IVH, and seizure activity for which they were receiving phenobarbital therapy (nine patients)." | 3.67 | Phenobarbital increases the theophylline requirement of premature infants being treated for apnea. ( Gottschalk, SK; Kissling, GE; Schuth, CR; Tran, TH; Yazdani, M, 1987) |
| "Phenobarbital was compared to no intervention or placebo." | 3.01 | Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants. ( Bruschettini, M; Odd, DE; Romantsik, O; Smit, E, 2023) |
| "Women in preterm labor ( < 35 weeks' gestation) were assigned to control and treatment groups." | 2.68 | Antenatal phenobarbital therapy and neonatal outcome. I: Effect on intracranial hemorrhage. ( Bedard, MP; Cepeda, E; Johnson, S; Kazzi, SN; Mariona, F; Muran, G; Poland, R; Shankaran, S, 1996) |
| "Maternal demographics, pregnancy complications, antenatal management, and route of delivery did not differ between the phenobarbital group (n = 50) and the placebo group (n = 60)." | 2.67 | Antenatal phenobarbital for the prevention of periventricular and intraventricular hemorrhage: a double-blind, randomized, placebo-controlled, multihospital trial. ( Hale, K; Kaempf, JW; Molina, R; Pantoja, AF; Porreco, R; Rosenberg, AA, 1990) |
| "Phenobarbital was associated with an increased risk of developing any subependymal-intraventricular-intraparenchymal hemorrhage and was not associated with a diminished risk of either severe hemorrhage or germinal matrix hemorrhage." | 2.66 | Neonatal intracranial hemorrhage and phenobarbital. ( Baglivo, JA; Brown, ER; Cleveland, RH; Huff, KR; Krishnamoorthy, KS; Kuban, KC; Leviton, A; Sullivan, KF; Teele, RL; White, S, 1986) |
| "Phenobarbital-treated infants were over eight times more likely to experience IVH than were untreated infants." | 2.66 | Effect of phenobarbital on motor activity and intraventricular hemorrhage in preterm infants with respiratory disease weighing less than 1500 grams. ( Marshall, RE; Miller, RH; Moore, JA; Porter, FL, 1985) |
| "The phenobarbital-treated infants who bled, however, were also significantly larger and more mature than control infants who bled." | 2.65 | Effect of prophylactic phenobarbital on intraventricular hemorrhage in high-risk infants. ( Bedard, MP; Dayal, B; Pantoja, A; Poland, RL; Shankaran, S; Slovis, TL, 1984) |
| "Phenobarbital has been suggested as a safe treatment that stabilises blood pressure and may protect against free radicals." | 2.49 | Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants. ( Odd, D; Smit, E; Whitelaw, A, 2013) |
| "Phenobarbital has been suggested as a safe treatment that stabilises blood pressure and may protect against free radicals." | 2.44 | Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants. ( Odd, D; Whitelaw, A, 2007) |
| "Her first pregnancy was complicated by premature labour, which led to delivery at 30 weeks' gestation." | 2.41 | Antenatal phenobarbital for prevention of intraventricular hemorrhage in preterm infants. ( Klinger, G; Koren, G, 2000) |
| "It is the recommended drug for the treatment of seizures in term neonates." | 2.37 | [Phenobarbital in newborn infants. Overview]. ( Staudt, F, 1984) |
| "Phenobarbital sodium (PhS) has been used in anticonvulsant concentrations in premature newborns in attempts to prevent peri- and intraventricular hemorrhages (PIVH)." | 1.29 | Phenobarbital and cerebral blood flow during hypotension in newborn pigs. ( Contant, CF; Goddard-Finegold, J; Martin, CG; Michael, LH; Yamashita, Y, 1993) |
| "Cerebral cavernous angioma (cavernoma) has previously been treated by resection for all presentations when surgically resectable." | 1.28 | Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases. ( Churchyard, A; Grainger, K; Khangure, M, 1992) |
| "Hypertonia and hyperreflexia/ankle clonus were most common." | 1.28 | Periventricular-intraventricular hemorrhage, sonographic localization, phenobarbital, and motor abnormalities in low birth weight infants. ( Allred, EN; Brown, ER; Krishnamoorthy, KS; Kuban, KC; Leviton, A; Sullivan, KF, 1990) |
| "Seizures were classified as subtle, multifocal clonic, generalized tonic, focal clonic, and myoclonic." | 1.27 | Seizures in the neonatal intensive care unit of the 1980s. Types, Etiologies, Timing. ( Calciolari, G; Perlman, JM; Volpe, JJ, 1988) |
| "Phenobarbital sodium has been given to premature infants in anticonvulsant dosages in attempts to prevent hemorrhages, but its efficacy in clinical studies has been disputed." | 1.27 | Reduction in incidence of periventricular, intraventricular hemorrhages in hypertensive newborn beagles pretreated with phenobarbital. ( Armstrong, DL; Goddard-Finegold, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 56 (56.00) | 18.7374 |
| 1990's | 29 (29.00) | 18.2507 |
| 2000's | 11 (11.00) | 29.6817 |
| 2010's | 2 (2.00) | 24.3611 |
| 2020's | 2 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romantsik, O | 2 |
| Smit, E | 2 |
| Odd, DE | 1 |
| Bruschettini, M | 2 |
| Stróżyk, A | 1 |
| Paraskevas, T | 1 |
| Calevo, MG | 1 |
| Banzi, R | 1 |
| Ley, D | 1 |
| Odd, D | 2 |
| Whitelaw, A | 5 |
| McCrea, HJ | 1 |
| Ment, LR | 3 |
| Crowther, CA | 4 |
| Crosby, DD | 1 |
| Henderson-Smart, DJ | 4 |
| Crowther, C | 1 |
| Henderson-Smart, D | 1 |
| Tramonte, JJ | 1 |
| Goodkin, HP | 1 |
| Slŭncheva, B | 1 |
| Vakrilova, L | 1 |
| Emilova, Z | 1 |
| Kalaĭdzhieva, M | 1 |
| Garnizov, T | 1 |
| Jiménez, R | 1 |
| Donn, SM | 4 |
| Roloff, DW | 4 |
| Goldstein, GW | 4 |
| Cooke, RW | 4 |
| Morgan, ME | 4 |
| Massey, RF | 2 |
| Hope, PL | 2 |
| Thorburn, RJ | 2 |
| Stewart, AL | 2 |
| Reynolds, EO | 2 |
| Whitehead, MD | 1 |
| Lowe, D | 1 |
| Placzek, M | 1 |
| Dubowitz, L | 1 |
| Lary, S | 1 |
| Levene, M | 1 |
| Gouyon, JB | 1 |
| Giroud, M | 1 |
| Bedard, MP | 3 |
| Shankaran, S | 6 |
| Slovis, TL | 1 |
| Pantoja, A | 1 |
| Dayal, B | 1 |
| Poland, RL | 2 |
| Staudt, F | 1 |
| Wimberley, PD | 1 |
| Lou, HC | 1 |
| Pedersen, H | 1 |
| Hejl, M | 1 |
| Lassen, NA | 1 |
| Friis-Hansen, B | 1 |
| Bale, JF | 1 |
| Allen, RW | 1 |
| Hulme, J | 1 |
| Wyman, ML | 1 |
| Koenigsberger, MR | 1 |
| Lastra, C | 1 |
| Thorp, JA | 4 |
| Ferrette-Smith, D | 2 |
| Gaston, LA | 1 |
| Johnson, J | 2 |
| Yeast, JD | 1 |
| Meyer, B | 1 |
| Abdel-Rahman, AM | 1 |
| Rosenberg, AA | 2 |
| De Lia, JE | 1 |
| Billman, D | 1 |
| Parriott, J | 1 |
| Meyer, BA | 1 |
| Cohen, GR | 1 |
| Yamashita, Y | 1 |
| Goddard-Finegold, J | 4 |
| Contant, CF | 1 |
| Martin, CG | 1 |
| Michael, LH | 2 |
| Barnes, ER | 1 |
| Thompson, DF | 1 |
| Bell, AH | 1 |
| Greisen, G | 2 |
| Pryds, O | 1 |
| Leviton, A | 10 |
| Kuban, KC | 10 |
| Pagano, M | 7 |
| Allred, EN | 5 |
| Van Marter, L | 1 |
| Mas-Muñoz, RL | 1 |
| Udaeta-Mora, E | 1 |
| Barrera-Reyes, RH | 1 |
| Rivera-Rueda, MA | 1 |
| Morales-Suárez, M | 1 |
| Cepeda, E | 1 |
| Muran, G | 1 |
| Mariona, F | 2 |
| Johnson, S | 1 |
| Kazzi, SN | 1 |
| Poland, R | 1 |
| Woldt, E | 1 |
| Nelson, J | 1 |
| Bedard, M | 1 |
| Delaney-Black, V | 1 |
| Doyle, L | 1 |
| McKenzie, DR | 1 |
| Papile, LA | 1 |
| Wright, LL | 1 |
| Ehrenkranz, RA | 2 |
| Mele, L | 1 |
| Lemons, JA | 1 |
| Korones, SB | 1 |
| Stevenson, DK | 1 |
| Donovan, EF | 1 |
| Stoll, BJ | 1 |
| Fanaroff, AA | 1 |
| Oh, W | 1 |
| Arroyo-Cabrales, LM | 1 |
| Garza-Morales, S | 1 |
| Hernández-Peláez, G | 1 |
| Tholl, DA | 1 |
| Miller, TQ | 1 |
| Henderson, WG | 1 |
| Myers, TF | 1 |
| O'Connor, M | 1 |
| Jones, AM | 1 |
| Hoffman, EL | 1 |
| Belden, B | 1 |
| Klinger, G | 1 |
| Koren, G | 1 |
| Scalais, E | 1 |
| Beharry, K | 1 |
| Papageorgiou, A | 1 |
| Bureau, M | 1 |
| Aranda, JV | 1 |
| Churchyard, A | 1 |
| Khangure, M | 1 |
| Grainger, K | 1 |
| Fenton, T | 1 |
| Strassfeld, R | 1 |
| Wolff, M | 1 |
| Van Marter, LJ | 1 |
| Saliba, E | 1 |
| Autret, E | 1 |
| Khadiry, L | 1 |
| Chamboux, C | 1 |
| Laugier, J | 1 |
| Morales, WJ | 2 |
| Iyer, P | 1 |
| Shann, F | 1 |
| Krishnamoorthy, KS | 4 |
| Sullivan, KF | 6 |
| Brown, ER | 5 |
| Donley, DK | 1 |
| Adham, BI | 1 |
| Kaempf, JW | 1 |
| Porreco, R | 1 |
| Molina, R | 1 |
| Hale, K | 1 |
| Pantoja, AF | 1 |
| Ruth, V | 1 |
| Virkola, K | 1 |
| Paetau, R | 1 |
| Raivio, KO | 1 |
| Volpe, JJ | 4 |
| Rayburn, W | 1 |
| Donn, S | 1 |
| Compton, A | 1 |
| Piehl, E | 1 |
| Schneider, D | 1 |
| Engelmann, L | 1 |
| Perlman, JM | 3 |
| Ernest, A | 1 |
| Stein, JG | 1 |
| Valaes, TN | 1 |
| Skouteli, H | 1 |
| Cherer, A | 1 |
| Brown, E | 1 |
| Allred, E | 2 |
| Duncan, CC | 1 |
| De Carolis, S | 1 |
| De Carolis, MP | 1 |
| Caruso, A | 1 |
| Oliva, GC | 1 |
| Romagnoli, C | 1 |
| Ferrazzani, S | 1 |
| Muzii, U | 1 |
| Luciano, R | 1 |
| Mancuso, S | 1 |
| Calciolari, G | 1 |
| Epstein, MF | 1 |
| Meltzer, C | 1 |
| Skouteli, HN | 1 |
| Kauffman, RE | 2 |
| Cepeda, EE | 2 |
| Ilagan, N | 2 |
| Hassan, M | 1 |
| Bhatia, R | 1 |
| Ostrea, E | 1 |
| Anwar, M | 1 |
| Kadam, S | 1 |
| Hiatt, IM | 1 |
| Hegyi, T | 1 |
| Teele, RL | 1 |
| Baglivo, JA | 1 |
| Huff, KR | 1 |
| White, S | 1 |
| Cleveland, RH | 1 |
| Armstrong, DL | 1 |
| Mizrahi, EM | 1 |
| Krishnamoorthy, K | 1 |
| Baglivo, J | 1 |
| Koerten, J | 1 |
| Acs, H | 1 |
| Kilchevsky, E | 1 |
| Yazdani, M | 1 |
| Kissling, GE | 1 |
| Tran, TH | 1 |
| Gottschalk, SK | 1 |
| Schuth, CR | 1 |
| Battisti, OG | 1 |
| Bertrand, JM | 1 |
| Langhendries, JP | 1 |
| Sanchez-Ramos, L | 1 |
| Jarrett, RV | 1 |
| Jordan, GD | 1 |
| Boynton, BR | 1 |
| Merritt, TA | 1 |
| Frederiksen, PS | 1 |
| Hertel, J | 1 |
| Christensen, NJ | 1 |
| Porter, FL | 1 |
| Marshall, RE | 1 |
| Moore, JA | 1 |
| Miller, RH | 1 |
| Alexander, E | 1 |
| Zavon, MR | 1 |
| Carroll, BJ | 1 |
| Ransohoff, J | 1 |
| Goodgold, A | 1 |
| Benjamin, MV | 1 |
| Monod, N | 1 |
| Dreyfus-Brisac, C | 1 |
| Sfaello, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Clinical Trial of Antenatal Phenobarbital in the Prevention of Neonatal Intracranial Hemorrhage[NCT00009620] | Phase 3 | 610 participants (Actual) | Interventional | 1993-02-28 | Completed | ||
| Follow-up Visit of High Risk Infants[NCT00009633] | 68,000 participants (Anticipated) | Observational | 1993-01-31 | Recruiting | |||
| [NCT00005293] | 0 participants | Observational | 1988-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
25 reviews available for phenobarbital and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Female; Humans; Hydrocephalus; Infant; Infant, Newborn; Infant, Premature; Infa | 2023 |
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews.
Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, N | 2023 |
Postnatal phenobarbital for the prevention of intraventricular haemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Humans; Infant, Newborn | 2013 |
The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Coagulants; Cyclooxygenase Inhibitors; Factor VIIa; Humans | 2008 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, New | 2010 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, New | 2003 |
Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Humans; Infant, Newborn | 2007 |
[Advances in neonatology: vitamin K, intracranial hemorrhage, arterial pressure, hemolytic disease].
Topics: Antihypertensive Agents; Blood Coagulation Disorders; Cerebral Hemorrhage; Erythroblastosis, Fetal; | 1984 |
[Indications for phenobarbital in neonatal pathology].
Topics: Asphyxia Neonatorum; Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases; Jaundi | 1983 |
[Phenobarbital in newborn infants. Overview].
Topics: Asphyxia Neonatorum; Brain Injuries; Cerebral Hemorrhage; Electroencephalography; Half-Life; Humans; | 1984 |
[Intraventricular hemorrhage in a newborn].
Topics: Anticonvulsants; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, Newborn; Obstetri | 1995 |
Prevention of intraventricular hemorrhage in the premature infant.
Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Fetal Diseases; Humans; | 1994 |
Meta-analysis of phenobarbital usage for prevention of intraventricular hemorrhage in premature infants: factors related to variation in outcome.
Topics: Birth Weight; Cerebral Hemorrhage; Cerebral Ventricles; Double-Blind Method; Female; Gestational Age | 1994 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Prematu | 2000 |
Postnatal phenobarbitone for the prevention of intraventricular hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Humans; Infant, Newborn | 2000 |
Antenatal phenobarbital for prevention of intraventricular hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; | 2000 |
Postnatal phenobarbitone for the prevention of intraventricular hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Humans; Infant, Newborn | 2001 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, New | 2001 |
Antenatal therapy to minimize neonatal intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant, Newborn; Phenobarbital; Pregnancy; Prenat | 1991 |
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Ethamsylate; Humans; In | 1988 |
Intraventricular hemorrhage in the premature infant--current concepts. Part II.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Combined Modality Therapy; Echoencephalography; Ethamsylat | 1989 |
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials | 1988 |
Prevention of neonatal intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Ethamsylate; Humans; Indometh | 1987 |
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Ind | 1986 |
Treatment of organophosphorus and chlorinated hydrocarbon insecticide intoxications.
Topics: Atropine; Cerebral Hemorrhage; Cholinesterase Inhibitors; Diagnosis, Differential; Gastroenteritis; | 1971 |
38 trials available for phenobarbital and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
[Prevention of brain hemorrhage in infants with low and extremely low birth weight and infants treated with surfactants. Late observation].
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Drug Therapy, Combination; Humans; Indomethacin; I | 2006 |
Prevention of intraventricular haemorrhage in preterm infants by phenobarbitone. A controlled trial.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Female; Humans; Infant, Low Birt | 1981 |
Phenobarbitone to prevent intraventricular haemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, | 1981 |
Failure of phenobarbitone to prevent neonatal intraventricular haemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Double-Blind Method; Humans; Inf | 1982 |
Phenobarbitone and neonatal intraventricular haemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, | 1982 |
Phenobarbitone for prevention of periventricular haemorrhage in very low birth-weight infants. A randomised double-blind trial.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Double-Blind Method; Evaluation | 1983 |
Phenobarbitone to prevent periventricular haemorrhage in very-low-birthweight babies.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant, Low Birth Weight; Infant, Newborn; Ph | 1984 |
Effect of prophylactic phenobarbital on intraventricular hemorrhage in high-risk infants.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Premature, Diseases; | 1984 |
Does phenobarbitone prevent periventricular hemorrhage in very low-birth-weight babies?: a controlled trial.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant, Low Birth Weight; Infant, Newborn; In | 1982 |
Further observations on the use of phenobarbital to prevent neonatal intracranial hemorrhage.
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital | 1982 |
Combined antenatal vitamin K and phenobarbital therapy for preventing intracranial hemorrhage in newborns less than 34 weeks' gestation.
Topics: Adolescent; Adult; Algorithms; Cerebral Hemorrhage; Double-Blind Method; Drug Therapy, Combination; | 1995 |
Antepartum vitamin K and phenobarbital for preventing intraventricular hemorrhage in the premature newborn: a randomized, double-blind, placebo-controlled trial.
Topics: Cerebral Hemorrhage; Diseases in Twins; Double-Blind Method; Humans; Infant, Newborn; Infant, Premat | 1994 |
Antepartum vitamin K and phenobarbital for preventing intraventricular hemorrhage in the premature newborn: a randomized, double-blind, placebo-controlled trial.
Topics: Cerebral Hemorrhage; Double-Blind Method; Female; Humans; Infant, Newborn; Infant, Premature, Diseas | 1994 |
Antenatal corticosteroids appear to reduce the risk of postnatal germinal matrix hemorrhage in intubated low birth weight newborns.
Topics: Cerebral Hemorrhage; Glucocorticoids; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Pre | 1993 |
[The effect of phenobarbital on the severity of intraventricular hemorrhage].
Topics: Cerebral Hemorrhage; Ependyma; Female; Humans; Incidence; Infant, Newborn; Infant, Premature; Infant | 1993 |
Antenatal phenobarbital therapy and neonatal outcome. I: Effect on intracranial hemorrhage.
Topics: Administration, Oral; Adult; Anticonvulsants; Birth Weight; Cerebral Hemorrhage; Female; Gestational | 1996 |
Antenatal phenobarbital therapy and neonatal outcome. II: Neurodevelopmental outcome at 36 months.
Topics: Anticonvulsants; Body Height; Body Weight; Cerebral Hemorrhage; Child Development; Child, Preschool; | 1996 |
The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants.
Topics: Adult; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, D | 1997 |
The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants.
Topics: Adult; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, D | 1997 |
The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants.
Topics: Adult; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, D | 1997 |
The effect of antenatal phenobarbital therapy on neonatal intracranial hemorrhage in preterm infants.
Topics: Adult; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, D | 1997 |
Use of prenatal phenobarbital in the prevention of subependymal/intraventricular hemorrhage in premature infants.
Topics: Adult; Cerebral Hemorrhage; Cerebral Ventricles; Double-Blind Method; Female; Gestational Age; Human | 1998 |
Does perinatal phenobarbital exposure affect developmental outcome at age 2?
Topics: Adult; Anticonvulsants; Central Nervous System Depressants; Cerebral Hemorrhage; Chi-Square Distribu | 1999 |
Rate of bronchopulmonary dysplasia as a function of neonatal intensive care practices.
Topics: Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Female; Humans; Incidence; Infant, Newborn; Intensi | 1992 |
Effects of phenobarbital on cerebral hemodynamics in preterm neonates.
Topics: Birth Weight; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Gestational Age; Hum | 1991 |
The epidemiology of germinal matrix hemorrhage during the first half-day of life.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cross-Sectional Studies; Echoencephalography; Ependyma; Hu | 1991 |
Antenatal phenobarbital for the prevention of periventricular and intraventricular hemorrhage: a double-blind, randomized, placebo-controlled, multihospital trial.
Topics: Adult; Apgar Score; Cerebral Hemorrhage; Cerebral Ventricles; Colorado; Double-Blind Method; Female; | 1990 |
Early high-dose phenobarbital treatment for prevention of hypoxic-ischemic brain damage in very low birth weight infants.
Topics: Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Developmental Disabilities; Drug Adminis | 1988 |
Maternal toxemia and neonatal germinal matrix hemorrhage in intubated infants less than 1751 g.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Female; Humans; Infant, Low Birth Weight; Infant, New | 1988 |
Hemorrhage, phenobarbital, and fluctuating cerebral blood flow velocity in the neonate.
Topics: Blood Flow Velocity; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Coh | 1988 |
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials | 1988 |
Antenatal phenobarbital in preventing intraventricular hemorrhage in premature newborns.
Topics: Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; | 1988 |
Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies.
Topics: Bilirubin; Birth Weight; Cerebral Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Phe | 1988 |
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Ind | 1986 |
Antenatal phenobarbital for the prevention of neonatal intracerebral hemorrhage.
Topics: Cerebral Hemorrhage; Drug Evaluation; Female; Fetal Blood; Humans; Infant Mortality; Infant, Newborn | 1986 |
Phenobarbitone prophylaxis of intraventricular haemorrhage.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Premature, Diseases; | 1986 |
Neonatal intracranial hemorrhage and phenobarbital.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Double-Blind Method; Gestational | 1986 |
Respiratory complications in low-birth-weight infants who received phenobarbital.
Topics: Cerebral Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; | 1987 |
Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital.
Topics: Administration, Oral; Cerebral Hemorrhage; Female; Fetal Monitoring; Fetal Organ Maturity; Humans; I | 1986 |
Phenobarbital and intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant; Phenobarbital | 1985 |
Effect of phenobarbital on motor activity and intraventricular hemorrhage in preterm infants with respiratory disease weighing less than 1500 grams.
Topics: Apgar Score; Cerebral Hemorrhage; Cerebral Ventricles; Humans; Infant, Low Birth Weight; Infant, New | 1985 |
39 other studies available for phenobarbital and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Prenatal phenobarbital before very-preterm birth and neurodevelopmental outcome.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Humans; Infant, Newborn; Infant, Premature, Diseases; | 2002 |
Temporal lobe hemorrhage in the full-term neonate presenting as apneic seizures.
Topics: Adult; Apnea; Cerebral Hemorrhage; Electroencephalography; Female; Humans; Infant, Newborn; Magnetic | 2004 |
Prevention of intraventricular haemorrhage by phenobarbitone.
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital | 1981 |
Phenobarbitone in neonatal intraventricular haemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Child, Preschool; Follow-Up Studies; Humans; Infant; Infan | 1981 |
Failure of phenobarbitone to prevent intraventricular haemorrhage in small preterm infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Humans; Infant, Newborn; Infant, Premature, Diseases; Phen | 1982 |
Phenobarbitone to prevent periventricular haemorrhage.
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases; Injections, Intramuscular; | 1982 |
Intracranial haemorrhage.
Topics: Arrhythmias, Cardiac; Cerebral Hemorrhage; Cerebral Ventricles; Cerebrospinal Fluid Shunts; Humans; | 1983 |
Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Abolition by phenobarbitone sedation.
Topics: Blood Pressure; Cerebral Hemorrhage; Female; Humans; Hypertension; Infant, Newborn; Infant, Prematur | 1982 |
Anterior spinal artery syndrome during the postpartum period.
Topics: Adult; Cerebral Hemorrhage; Epilepsy; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange | 1981 |
Phenobarbital and cerebral blood flow during hypotension in newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Hypoten | 1993 |
Antenatal phenobarbital to prevent or minimize intraventricular hemorrhage in the low-birthweight neonate.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; | 1993 |
Comparison of the effects of phenobarbitone and morphine administration on EEG activity in preterm babies.
Topics: Calcium; Cerebral Hemorrhage; Electroencephalography; Humans; Infant, Newborn; Infant, Premature; Mo | 1993 |
Antenatal phenobarbitone and neonatal outcome.
Topics: Administration, Oral; Anticonvulsants; Cerebral Hemorrhage; Child Development; Female; Fetal Membran | 1996 |
Antenatal phenobarbital therapy and neonatal income.
Topics: Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases | 1997 |
Effects of phenobarbital on cerebral blood flow in the newborn piglet.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Glucose; Body Temperature; Brain Chemistry; Cer | 1992 |
Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases.
Topics: Adolescent; Adult; Angiography; Brain Neoplasms; Carbamazepine; Cerebral Hemorrhage; Child; Epilepsy | 1992 |
Maternal toxemia is associated with reduced incidence of germinal matrix hemorrhage in premature babies.
Topics: Cerebral Hemorrhage; Cerebral Palsy; Double-Blind Method; Female; Humans; Hypertension; Infant, Newb | 1992 |
Antenatal phenobarbital to prevent intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Phenob | 1991 |
Periventricular-intraventricular hemorrhage, sonographic localization, phenobarbital, and motor abnormalities in low birth weight infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Follow-Up Studies; Humans; Infant; Infant, Low Birth Weigh | 1990 |
Phenobarbital and cerebral blood flow during hypertension in the newborn beagle.
Topics: Acidosis; Animals; Animals, Newborn; Cerebral Hemorrhage; Cerebrovascular Circulation; Dogs; Hemodyn | 1990 |
Oral phenobarbital given antenatally to reduce neonatal intraventricular hemorrhage. A comparison between maternal and umbilical cord serum levels at delivery.
Topics: Administration, Oral; Cerebral Hemorrhage; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obst | 1989 |
[Sense and nonsense in barbiturate-induced functional paralysis for the protective and therapeutic decrease in cerebral oxygen requirements].
Topics: Brain; Cerebral Hemorrhage; Cerebral Infarction; Coma; Hemodynamics; Humans; Oxygen Consumption; Phe | 1988 |
Hemorrhage, phenobarbital, and fluctuating cerebral blood flow.
Topics: Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Humans; Infant, Newborn; Phenobarb | 1989 |
Bilirubin, intraventricular hemorrhage, and phenobarbital.
Topics: Bilirubin; Cerebral Hemorrhage; Humans; Infant, Newborn; Phenobarbital; Phototherapy | 1989 |
Seizures in the neonatal intensive care unit of the 1980s. Types, Etiologies, Timing.
Topics: Cerebral Hemorrhage; Cerebrovascular Disorders; Epilepsy; Female; Gestational Age; Humans; Infant, L | 1988 |
Reduction in incidence of periventricular, intraventricular hemorrhages in hypertensive newborn beagles pretreated with phenobarbital.
Topics: Animals; Animals, Newborn; Blood Pressure; Cerebral Hemorrhage; Dogs; Hypertension; Phenobarbital; P | 1987 |
Understanding and preventing perinatal, intracerebral, peri- and intraventricular hemorrhage.
Topics: Blood Pressure; Brain; Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Electr | 1987 |
Prevention of intraventricular hemorrhage with phenobarbital therapy: now what?
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Prospectiv | 1986 |
Pharmacokinetic basis for antenatal dosing of phenobarbital for the prevention of neonatal intracerebral hemorrhage.
Topics: Cerebral Hemorrhage; Female; Fetal Blood; Half-Life; Humans; Infant, Newborn; Infant, Premature, Dis | 1986 |
Cranial bruising and intraventricular hemorrhage.
Topics: Birth Injuries; Cerebral Hemorrhage; Craniocerebral Trauma; Humans; Infant, Newborn; Phenobarbital | 1986 |
Phenobarbital increases the theophylline requirement of premature infants being treated for apnea.
Topics: Apnea; Cerebral Hemorrhage; Drug Interactions; Humans; Infant, Newborn; Infant, Premature; Phenobarb | 1987 |
Neonatal intracranial hemorrhage and phenobarbital.
Topics: Cerebral Hemorrhage; Humans; Infant, Newborn; Phenobarbital | 1987 |
Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital.
Topics: Cerebral Hemorrhage; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Phenobarbital; Pregn | 1987 |
Additional statistical analysis of antenatal phenobarbital for prevention of neonatal intracerebral hemorrhage.
Topics: Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Phenobarbital; Pregna | 1987 |
Catecholamine response to chest physiotherapy and endotracheal suctioning in preterm infants.
Topics: Acidosis; Blood Pressure; Cerebral Hemorrhage; Epinephrine; Humans; Infant Care; Infant, Newborn; In | 1985 |
Medical management of closed head injuries.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Anti-Bacterial Agents; Blood Transfusion; Cerebral Angi | 1972 |
Barbiturate overdosage: presentation with focal neurological signs.
Topics: Adult; Alcoholism; Amobarbital; Barbiturates; Basilar Artery; Bromides; Cerebral Hemorrhage; Coma; C | 1969 |
Preoperative management of patients with ruptured intracranial aneurysms.
Topics: Adult; Aged; Aminocaproates; Antifibrinolytic Agents; Antihypertensive Agents; Blood Pressure; Carot | 1972 |
[Detection and prognosis of the neonatal mal according to the electroclinical study of 150 cases].
Topics: Cerebral Hemorrhage; Cerebrovascular Disorders; Congenital Abnormalities; Electroencephalography; Ep | 1969 |