phenobarbital has been researched along with Bradycardia in 6 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance." | 7.77 | Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011) |
| "The failure of the maximum tolerated dosage to improve seizure control in dogs with phenobarbital-resistant epilepsy argues against the suitability of verapamil add-on treatment to overcome pharmacoresistance." | 3.77 | Add-on treatment with verapamil in pharmacoresistant canine epilepsy. ( Jambroszyk, M; Potschka, H; Tipold, A, 2011) |
| "Type II (tonic) seizures are invariably associated with profound transient bradycardia, recovery from which begins about the time the tonic seizure phase ends." | 1.26 | Changes in heart rate associated with high-pressure convulsions in rodents. ( Beaver, RW; Brauer, RW; Fuquay, J, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jambroszyk, M | 1 |
| Tipold, A | 1 |
| Potschka, H | 1 |
| KAROLY, AJ | 1 |
| DOMINO, EF | 1 |
| WALKER, EL | 1 |
| Wiriyathian, S | 1 |
| Kaojarern, S | 1 |
| Rosenfeld, CR | 1 |
| Korzets, Z | 1 |
| Ben-Chitrit, S | 1 |
| Bernheim, J | 1 |
| Beaver, RW | 1 |
| Brauer, RW | 1 |
| Fuquay, J | 1 |
| Méhes, J | 1 |
| Decsi, L | 1 |
| Várszegi, MK | 1 |
| Hideg, H | 1 |
| Hankovszky, OH | 1 |
6 other studies available for phenobarbital and Bradycardia
| Article | Year |
|---|---|
Add-on treatment with verapamil in pharmacoresistant canine epilepsy.
Topics: Age of Onset; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blo | 2011 |
DIFFERENTIAL EFFECTS OF VARIOUS DRUGS ON THE CONDITIONED MOTOR AND HEART RATE RESPONSES IN DOGS RESISTANT TO EXTINCTION.
Topics: Bradycardia; Chlorpromazine; Conditioning, Classical; Decamethonium Compounds; Dogs; Heart; Heart Ra | 1964 |
Dilantin toxicity in a preterm infant: persistent bradycardia and lethargy.
Topics: Bradycardia; Dose-Response Relationship, Drug; Heart; Humans; Infant, Newborn; Infant, Premature, Di | 1982 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedip | 1994 |
Changes in heart rate associated with high-pressure convulsions in rodents.
Topics: Age Factors; Animals; Atmospheric Pressure; Atropine; Bradycardia; Female; Heart Rate; Mice; Phenoba | 1979 |
Inhibitory effect of 1-alkylbenzimidazoles on gastric secretion in the rat.
Topics: Acetylcholine; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Carbachol; Cats; Central Nerv | 1966 |