Page last updated: 2024-11-02

phenobarbital and Bladder Diseases

phenobarbital has been researched along with Bladder Diseases in 1 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"Phenobarbital pretreatment of the rats, which is known to enhance hepatic microsomal activation of CP, protected against CP-induced urinary bladder toxicity and the depression of hepatic MFO activities."1.27Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide. ( Bansal, SK; Gurtoo, HL; Pavelic, Z; Struck, RF, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurtoo, HL1
Bansal, SK1
Pavelic, Z1
Struck, RF1

Other Studies

1 other study available for phenobarbital and Bladder Diseases

ArticleYear
Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide.
    British journal of cancer, 1985, Volume: 51, Issue:1

    Topics: Animals; Cyclophosphamide; Drug Interactions; Intestines; Kidney; Liver; Lung; Male; Microsomes, Liv

1985