phenobarbital has been researched along with Bladder Diseases in 1 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Excerpt | Relevance | Reference |
---|---|---|
"Phenobarbital pretreatment of the rats, which is known to enhance hepatic microsomal activation of CP, protected against CP-induced urinary bladder toxicity and the depression of hepatic MFO activities." | 1.27 | Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide. ( Bansal, SK; Gurtoo, HL; Pavelic, Z; Struck, RF, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gurtoo, HL | 1 |
Bansal, SK | 1 |
Pavelic, Z | 1 |
Struck, RF | 1 |
1 other study available for phenobarbital and Bladder Diseases
Article | Year |
---|---|
Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide.
Topics: Animals; Cyclophosphamide; Drug Interactions; Intestines; Kidney; Liver; Lung; Male; Microsomes, Liv | 1985 |