phenobarbital has been researched along with Birth Weight in 67 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationships among serum bilirubin concentration on days 5 and 7, birth weight, the presence of intraventricular hemorrhage, and the receipt of phenobarbital were examined in a group of 232 newborns weighing less than 1,751 g who were intubated, mechanically ventilated by 12 hours after birth, and whose parents had given permission for a randomized trial of phenobarbital prophylaxis of intraventricular hemorrhage." | 9.06 | Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies. ( Brown, ER; Epstein, MF; Kuban, KC; Leviton, A; Meltzer, C; Pagano, M; Skouteli, HN; Sullivan, KF, 1988) |
| "Levetiracetam can be a good and safe choice for treatment of neonatal seizures in preterm infants." | 7.88 | Efficacy of levetiracetam for neonatal seizures in preterm infants. ( Han, JY; Lee, IG; Moon, CJ; Sung, IK; Youn, YA, 2018) |
| "The relationships among serum bilirubin concentration on days 5 and 7, birth weight, the presence of intraventricular hemorrhage, and the receipt of phenobarbital were examined in a group of 232 newborns weighing less than 1,751 g who were intubated, mechanically ventilated by 12 hours after birth, and whose parents had given permission for a randomized trial of phenobarbital prophylaxis of intraventricular hemorrhage." | 5.06 | Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies. ( Brown, ER; Epstein, MF; Kuban, KC; Leviton, A; Meltzer, C; Pagano, M; Skouteli, HN; Sullivan, KF, 1988) |
| "Levetiracetam can be a good and safe choice for treatment of neonatal seizures in preterm infants." | 3.88 | Efficacy of levetiracetam for neonatal seizures in preterm infants. ( Han, JY; Lee, IG; Moon, CJ; Sung, IK; Youn, YA, 2018) |
| "The effects of antiepileptic drugs (AED) on infants during pregnancy and delivery were studied in a total of 82 epileptic mothers on various monotherapies; 29 cases receiving valproic acid (VPA), 20 receiving phenytoin (PHT), 18 on carbamazepine (CBZ) and 15 on phenobarbital (PB)." | 3.68 | [Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital]. ( Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H, 1991) |
| "Phenobarbital has the advantage of low cost and simplicity." | 2.78 | High-dose phenobarbital or erythropoietin for the treatment of perinatal asphyxia in term newborns. ( Avasiloaiei, A; Dimitriu, C; Moscalu, M; Paduraru, L; Stamatin, M, 2013) |
| "Women in preterm labor ( < 35 weeks' gestation) were assigned to control and treatment groups." | 2.68 | Antenatal phenobarbital therapy and neonatal outcome. I: Effect on intracranial hemorrhage. ( Bedard, MP; Cepeda, E; Johnson, S; Kazzi, SN; Mariona, F; Muran, G; Poland, R; Shankaran, S, 1996) |
| " Therefore phenobarbitone does not have seem to have any significant effect on cerebral haemodynamics up to a dosage of 20 mg/kg, so that there is no apparent effect on the risk of cerebral haemorrhage." | 2.66 | [Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g]. ( Jorch, G; Michel, E; Rabe, H; Rickers, E; Stöhr, G; Süllwald, A, 1988) |
| "A population pharmacokinetic analysis was performed based on 372 PG plasma concentrations from 62 (pre)term neonates (birth weight (bBW) 630-3980 g, postnatal age (PNA) 1-30 days) using NONMEM 6." | 1.39 | Developmental pharmacokinetics of propylene glycol in preterm and term neonates. ( Allegaert, K; Danhof, M; De Cock, RF; de Hoon, J; Knibbe, CA; Kulo, A; Verbesselt, R, 2013) |
| "Pregnancies complicated by severe preeclampsia in the second trimester are associated with a high incidence of perinatal morbidity and mortality." | 1.27 | Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester. ( Abdella, TN; Anderson, GD; Brooks, TF; Sibai, BM; Spinnato, JA; Taslimi, M, 1985) |
| "Routine clinical pharmacokinetic (PK) data collected from 59 preterm infants who received phenobarbital were analyzed to estimate population PK parameters." | 1.27 | Neonatal population pharmacokinetics of phenobarbital derived from routine clinical data. ( Donn, SM; Grasela, TH, 1985) |
| " The risk of over dosage and the large individual variation in the metabolism of phenobarbitone in the new born lead us to recommend checking the blood levels when giving repeated doses." | 1.26 | [Pharmacokinetic data on phenobarbital. Study on the influence of gestational age and dysmaturity]. ( Humbert, F; Mur, JM; Pladys, JC; Royer, RJ; Royer-Morrot, MJ; Vert, P, 1976) |
| "A daily dosage of 100 mg phenobarbitone administered orally to pregnant women for three days or more immediately before delivery has reduced the various mortality rates for low-birth-weight infants by 50% or more." | 1.26 | Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment. ( Trolle, D, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (85.07) | 18.7374 |
| 1990's | 6 (8.96) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (5.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, JY | 1 |
| Moon, CJ | 1 |
| Youn, YA | 1 |
| Sung, IK | 1 |
| Lee, IG | 1 |
| Avasiloaiei, A | 1 |
| Dimitriu, C | 1 |
| Moscalu, M | 1 |
| Paduraru, L | 1 |
| Stamatin, M | 1 |
| Kraft, WK | 1 |
| Dysart, K | 1 |
| Greenspan, JS | 1 |
| Gibson, E | 1 |
| Kaltenbach, K | 1 |
| Ehrlich, ME | 1 |
| De Cock, RF | 1 |
| Knibbe, CA | 1 |
| Kulo, A | 1 |
| de Hoon, J | 1 |
| Verbesselt, R | 1 |
| Danhof, M | 1 |
| Allegaert, K | 1 |
| WINBERG, J | 1 |
| Ribon, B | 1 |
| Brazier, JL | 1 |
| Claris, O | 1 |
| Cortambert, F | 1 |
| Chouchane, N | 1 |
| Bannier, A | 1 |
| Salle, B | 1 |
| Cohen, MS | 1 |
| Painter, MJ | 1 |
| Minnigh, MB | 1 |
| Gaus, L | 1 |
| Scher, M | 1 |
| Brozanski, B | 1 |
| Alvin, J | 1 |
| Shankaran, S | 1 |
| Cepeda, E | 1 |
| Muran, G | 1 |
| Mariona, F | 1 |
| Johnson, S | 1 |
| Kazzi, SN | 1 |
| Poland, R | 1 |
| Bedard, MP | 1 |
| Tholl, DA | 1 |
| Miller, TQ | 1 |
| Henderson, WG | 1 |
| Myers, TF | 1 |
| Bartels, H | 1 |
| Fenner, A | 1 |
| van der Merwe, W | 1 |
| Barbalatt, S | 1 |
| Wolfsdorf, J | 1 |
| Martin, JC | 1 |
| Martin, DC | 1 |
| Lemire, R | 1 |
| Mackler, B | 1 |
| Thomas, CR | 1 |
| Royer, RJ | 1 |
| Vert, P | 1 |
| Mur, JM | 1 |
| Pladys, JC | 1 |
| Humbert, F | 1 |
| Royer-Morrot, MJ | 1 |
| Zemp, JW | 1 |
| Middaugh, LD | 1 |
| Vargas, GC | 1 |
| Pildes, RS | 1 |
| Vidyasagar, D | 1 |
| Keith, LG | 1 |
| Banerjee, U | 1 |
| Trolle, D | 2 |
| Reineke, J | 1 |
| Yerby, MS | 1 |
| Leavitt, A | 1 |
| Erickson, DM | 1 |
| McCormick, KB | 1 |
| Loewenson, RB | 1 |
| Sells, CJ | 1 |
| Benedetti, TJ | 1 |
| Saliba, E | 1 |
| Autret, E | 1 |
| Khadiry, L | 1 |
| Chamboux, C | 1 |
| Laugier, J | 1 |
| Tanaka, H | 1 |
| Takeda, A | 1 |
| Izumi, M | 1 |
| Okada, H | 1 |
| Ishikawa, S | 1 |
| Benda, GI | 1 |
| Engel, RC | 1 |
| Zhang, YP | 1 |
| Ching, M | 1 |
| Tang, L | 1 |
| Jorch, G | 1 |
| Rickers, E | 1 |
| Rabe, H | 1 |
| Stöhr, G | 1 |
| Süllwald, A | 1 |
| Michel, E | 1 |
| Epstein, MF | 1 |
| Leviton, A | 1 |
| Kuban, KC | 1 |
| Pagano, M | 1 |
| Meltzer, C | 1 |
| Skouteli, HN | 1 |
| Brown, ER | 1 |
| Sullivan, KF | 1 |
| Weinberger, SM | 1 |
| Kandall, SR | 2 |
| Doberczak, TM | 1 |
| Thornton, JC | 1 |
| Bernstein, J | 1 |
| Sibai, BM | 1 |
| Taslimi, M | 1 |
| Abdella, TN | 1 |
| Brooks, TF | 1 |
| Spinnato, JA | 1 |
| Anderson, GD | 1 |
| Grasela, TH | 1 |
| Donn, SM | 1 |
| McMullin, GP | 3 |
| Hayes, MF | 1 |
| Arora, SC | 1 |
| Robinson, RJ | 1 |
| Ramboer, C | 1 |
| Thompson, RP | 1 |
| Williams, R | 1 |
| Harper, RG | 2 |
| Solish, GI | 1 |
| Purow, HM | 1 |
| Sang, E | 1 |
| Panepinto, WC | 1 |
| Ihle, W | 1 |
| Eggert, W | 1 |
| Grauel, EL | 1 |
| Weh, L | 2 |
| Syllm-Rapoport, I | 2 |
| Rosanelli, K | 1 |
| Török, J | 1 |
| Blatman, S | 1 |
| Halpin, TF | 1 |
| Jones, AR | 1 |
| Bishop, HL | 1 |
| Lerner, S | 1 |
| Zwacka, G | 2 |
| Frenzel, J | 2 |
| Hodr, R | 2 |
| Plesingerová, I | 2 |
| Senkárcinová, V | 2 |
| Cao, A | 1 |
| Falorni, A | 1 |
| Fracassini, F | 1 |
| Lungarotti, MS | 1 |
| Gmyrek, D | 1 |
| Bunke, H | 1 |
| Cario, WR | 1 |
| Daberkow, H | 1 |
| Läuter, J | 1 |
| Saworra, H | 1 |
| Wong, YK | 1 |
| Wood, BS | 1 |
| Jalling, B | 1 |
| Boréus, LO | 1 |
| Kållberg, N | 1 |
| Agurell, S | 1 |
| Sereni, F | 1 |
| Mandelli, M | 1 |
| Principi, N | 1 |
| Tognoni, G | 1 |
| Pardi, G | 1 |
| Morselli, PL | 1 |
| Gartner, LM | 1 |
| Heubel, F | 1 |
| Levin, GE | 1 |
| Mobarak, AN | 1 |
| Valaes, T | 1 |
| Petmezaki, S | 1 |
| Doxiadis, SA | 1 |
| Valdes, OS | 1 |
| Maurer, HM | 1 |
| Shumway, CN | 1 |
| Draper, DA | 1 |
| Hossaini, AA | 1 |
| Menzel, K | 1 |
| Scholz, E | 1 |
| Behrman, RE | 1 |
| Fisher, D | 1 |
| Paton, JB | 1 |
| Keller, J | 1 |
| Gagyi, D | 1 |
| Frank, K | 1 |
| Dortmann, A | 1 |
| Haupt, H | 1 |
| Küster, F | 1 |
| Hinkel, GK | 1 |
| Schwarze, R | 1 |
| Kintzel, HW | 1 |
| Carswell, F | 1 |
| Kerr, MM | 1 |
| Dunsmore, IR | 1 |
| Glass, L | 1 |
| Evans, HE | 1 |
| Reddy, AM | 1 |
| Stern, G | 1 |
| Sinniah, D | 1 |
| Tay, LK | 1 |
| Dugdale, AE | 1 |
| Dean, D | 1 |
| Lucey, JF | 1 |
| Pritchard, JA | 1 |
| Scott, DE | 1 |
| Whalley, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Buprenorphine for the Treatment of Neonatal Abstinence Syndrome[NCT00521248] | Phase 1 | 60 participants (Anticipated) | Interventional | 2004-04-30 | Completed | ||
| Prospective Randomized Blinded Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)[NCT04455802] | Phase 3 | 0 participants (Actual) | Interventional | 2020-10-01 | Withdrawn (stopped due to termination of funding) | ||
| A Randomized, Active-Control, Double-Blind, Double-Dummy Clinical Trial Comparing Sublingual Buprenorphine And Morphine Solution For The Treatment Of Neonatal Opioid Abstinence Syndrome[NCT01452789] | Phase 3 | 63 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
This endpoint will compare length of stay in the hospital (in days) using sublingual buprenorphine or morphine solution. (NCT01452789)
Timeframe: Duration of hospital stay is an expected average of 5 weeks.
| Intervention | days (Median) |
|---|---|
| Sublingual Buprenorphine | 21 |
| Oral Morphine | 33 |
This endpoint will compare length of treatment (in days) using sublingual buprenorphine or oral morphine solution. (NCT01452789)
Timeframe: Patients will be followed for the duration of hospital stay, an expected average of 5 weeks.
| Intervention | days (Median) |
|---|---|
| Sublingual Buprenorphine | 15 |
| Oral Morphine | 28 |
Adverse events will be collected, graded by severity, and assessed for causality referent to study drug. (NCT01452789)
Timeframe: Patients will be followed for the duration of hospital stay, an expected average of 5 weeks.
| Intervention | Participants (Count of Participants) |
|---|---|
| Sublingual Buprenorphine | 7 |
| Oral Morphine | 8 |
This endpoint will compare requirement number of patients who require use of supplemental phenobarbital. (NCT01452789)
Timeframe: Patients will be followed for the duration of hospital stay, an expected average of 5 weeks.
| Intervention | participants (Number) |
|---|---|
| Sublingual Buprenorphine | 5 |
| Oral Morphine | 7 |
5 reviews available for phenobarbital and Birth Weight
| Article | Year |
|---|---|
Drug abuse in pregnancy: fetal ad neonatal effects.
Topics: Alcoholism; Birth Weight; Chlorpromazine; Diazepam; Female; Fetus; Humans; Infant, Newborn; Infant, | 1982 |
Meta-analysis of phenobarbital usage for prevention of intraventricular hemorrhage in premature infants: factors related to variation in outcome.
Topics: Birth Weight; Cerebral Hemorrhage; Cerebral Ventricles; Double-Blind Method; Female; Gestational Age | 1994 |
[Hyperbilirubinemia in premature infants during 1948-1973 (evaluation and therapy of physiological jaundice in newborn infants of low birth weight during the past 25 years)].
Topics: Adrenal Cortex Hormones; Birth Weight; Brain Diseases; Exchange Transfusion, Whole Blood; Gestationa | 1973 |
Narcotic poisoning of children (1) through accidental ingestion of methadone and (2) in utero.
Topics: Administration, Oral; Apgar Score; Birth Weight; Child; Child Care; Female; Gestational Age; Heroin | 1974 |
In utero disease and the newborn infant.
Topics: Acid-Base Equilibrium; Acidosis; Amniotic Fluid; Animals; Bilirubin; Birth Weight; Electrocardiograp | 1970 |
19 trials available for phenobarbital and Birth Weight
| Article | Year |
|---|---|
High-dose phenobarbital or erythropoietin for the treatment of perinatal asphyxia in term newborns.
Topics: Asphyxia Neonatorum; Birth Weight; Dose-Response Relationship, Drug; Epoetin Alfa; Erythropoietin; F | 2013 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
Topics: Administration, Sublingual; Adult; Birth Weight; Buprenorphine; Cytomegalovirus Infections; Dose-Res | 2011 |
Neonatal phenobarbital and phenytoin binding profiles.
Topics: Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Prot | 1994 |
Antenatal phenobarbital therapy and neonatal outcome. I: Effect on intracranial hemorrhage.
Topics: Administration, Oral; Adult; Anticonvulsants; Birth Weight; Cerebral Hemorrhage; Female; Gestational | 1996 |
Effects of phenobarbital on cerebral hemodynamics in preterm neonates.
Topics: Birth Weight; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Gestational Age; Hum | 1991 |
[Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g].
Topics: Birth Weight; Blood Flow Velocity; Cerebrovascular Circulation; Echoencephalography; Humans; Infant, | 1988 |
Bilirubin, intraventricular hemorrhage, and phenobarbital in very low birth weight babies.
Topics: Bilirubin; Birth Weight; Cerebral Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Phe | 1988 |
Phenobarbitone in rhesus haemolytic disease. A controlled trial.
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Erythroblastosis, Fetal; Exchange Transfusion, Wh | 1970 |
Phenobarbitone and neonatal jaundice.
Topics: Bilirubin; Birth Weight; Gestational Age; Humans; Infant, Newborn; Jaundice, Neonatal; Phenobarbital | 1968 |
A possible drop in first-week-mortality rate for low-birth-weight infants after phenobarbitone treatment.
Topics: Birth Weight; Clinical Trials as Topic; Humans; Infant Mortality; Infant, Newborn; Phenobarbital | 1968 |
Effect of phenobarbitone on low-birth-weight infants.
Topics: Birth Weight; Clinical Trials as Topic; Humans; Infant Mortality; Infant, Newborn; Phenobarbital | 1968 |
Controlled trials of phenobarbitone therapy of neonatal jaundice.
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Erythroblastosis, Fetal; Female; Humans; Infant, | 1969 |
[Current problems in the hyperbilirubinemia of premature infants].
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Enzyme Induction; Humans; Hyperbilirubinemia, Her | 1972 |
[Diazepam and phenobarbital in reduction of bilirubin level in newborn infants by non-sedative doses].
Topics: Bilirubin; Birth Weight; Breast Feeding; Contraceptives, Oral; Diazepam; Female; Gestational Age; Hu | 1974 |
Controlled trial of phenobarbitone in neonatal jaundice.
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Humans; Infant, Newborn; Jaundice, Neonatal; Phen | 1970 |
Effect on neonatal hyperbilirubinemia of phenobarbital during pregnancy or after birth: practical value of the treatment in a population with high risk of unexplained severe neonatal jaundice.
Topics: ABO Blood-Group System; Administration, Oral; Age Factors; Bilirubin; Birth Weight; Clinical Trials | 1970 |
Controlled clinical trial of phenobarbital and-or light in reducing neonatal hyperbilirubinemia in a predominantly Negro population.
Topics: Bilirubin; Birth Weight; Black or African American; Clinical Trials as Topic; Humans; Hyperbilirubin | 1971 |
[The effect of phenobarbitol treatment on hyperbilirubinemia and albumin binding capacity in premature infants].
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Enzyme Induction; Exchange Transfusion, Whole Blo | 1971 |
[The influence of combined therapy with orotic acid and phenobarbital on the level of serum bilirubin in premature infants].
Topics: Bilirubin; Birth Weight; Drug Combinations; Drug Synergism; Humans; Infant, Newborn; Infant, Prematu | 1972 |
43 other studies available for phenobarbital and Birth Weight
| Article | Year |
|---|---|
Efficacy of levetiracetam for neonatal seizures in preterm infants.
Topics: Anticonvulsants; Birth Weight; Brain; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem | 2018 |
Developmental pharmacokinetics of propylene glycol in preterm and term neonates.
Topics: Acetaminophen; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Mo | 2013 |
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Ca | 1964 |
Pharmacokinetic study in the premature newborn of a lyophilized form of phenobarbital.
Topics: Birth Weight; Female; Freeze Drying; Gestational Age; Humans; Infant, Newborn; Infant, Premature; In | 1984 |
Hepatic enzymes, their induction and usefulness in predicting maximal serum bilirubin levels in premature newborn infants.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Birth Weight; Enzyme Induction; gamma-Glutamyltra | 1977 |
Effects of maternal absorption of phenobarbital upon rat offspring development and function.
Topics: Animals; Behavior, Animal; Birth Weight; Conditioning, Operant; Ear, External; Female; Growth; Male; | 1979 |
Phenobarbital prophylaxis of neonatal hyperbilirubinemia. Evaluation of a nightly dose.
Topics: Birth Weight; Diseases in Twins; Drug Administration Schedule; Female; Humans; Indiana; Infant, Newb | 1977 |
[Pharmacokinetic data on phenobarbital. Study on the influence of gestational age and dysmaturity].
Topics: Birth Weight; Gestational Age; Half-Life; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, | 1976 |
Some effects of prenatal exposure to d-amphetamine sulfate and phenobarbital on developmental neurochemistry and on behavior.
Topics: Animals; Avoidance Learning; Behavior, Animal; Birth Weight; Body Weight; Brain; Brain Chemistry; Co | 1975 |
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet | 1975 |
Conditioned learning in young rats born of drug-addicted parents and raised on addictive drugs.
Topics: Animals; Animals, Newborn; Avoidance Learning; Birth Weight; Body Weight; Conditioning, Psychologica | 1975 |
Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment.
Topics: Birth Weight; Female; Fetal Death; Humans; Infant Mortality; Infant, Newborn; Infant, Premature; Phe | 1976 |
[Drug therapy in the prevention of transitory hyperbilirubinemia in premature newborn infants].
Topics: Birth Weight; Humans; Infant, Newborn; Jaundice, Neonatal; Nikethamide; Phenobarbital | 1976 |
Antiepileptics and the development of congenital anomalies.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Fe | 1992 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Feta | 1991 |
Prolonged inactive phases during the discontinuous pattern of prematurity in the electroencephalogram of very-low-birthweight infants.
Topics: Birth Weight; Brain; Cohort Studies; Electroencephalography; Follow-Up Studies; Humans; Infant, Newb | 1989 |
Neuroleptic drug-induced alterations on neonatal growth and development. I. Prenatal exposure influences birth size, mortality rate, and the neuroendocrine system.
Topics: Animals; Animals, Newborn; Birth Weight; Codeine; Dextroamphetamine; Embryonic and Fetal Development | 1986 |
Early weight-change patterns in neonatal abstinence.
Topics: Birth Weight; Body Weight; Energy Intake; Female; Humans; Infant, Newborn; Male; Maternal-Fetal Exch | 1986 |
Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester.
Topics: Administration, Oral; Antihypertensive Agents; Bed Rest; Birth Weight; Delivery, Obstetric; Diuretic | 1985 |
Neonatal population pharmacokinetics of phenobarbital derived from routine clinical data.
Topics: Birth Weight; Gestational Age; Half-Life; Humans; Infant, Newborn; Infant, Premature; Kinetics; Mode | 1985 |
Jaundice of the newborn and phenobarbitone.
Topics: Birth Weight; Brain Diseases; Erythroblastosis, Fetal; Female; Humans; Hyperbilirubinemia; Infant, N | 1971 |
The effect of a methadone treatment program upon pregnant heroin addicts and their newborn infants.
Topics: Adult; Birth Weight; Blood Glucose; Calcium; Female; Fetus; Gestational Age; Heroin Dependence; Huma | 1974 |
[Intravenous load by pheno-and hexobarbital in mature and premature newborn infants and young infants].
Topics: Birth Weight; Body Water; Hexobarbital; Humans; Infant, Newborn; Infant, Premature; Injections, Intr | 1974 |
Prophylaxis of neonatal hyperbilirubinemia with phenobarbital.
Topics: ABO Blood-Group System; Bilirubin; Birth Weight; Erythroblastosis, Fetal; Female; Gestational Age; H | 1972 |
[Influence of phenobarbital on glucoronic acid excretion in newborns].
Topics: Birth Weight; Glucuronates; Humans; Infant, Newborn; Male; Phenobarbital | 1972 |
[Phenobarbital and hyperbilirubinemia in newborn infants with low birth weight (1)].
Topics: Administration, Oral; Birth Weight; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Injections; | 1973 |
[Phenobarbital and hyperbilirubinemia of newborn infants with low birth weight. II].
Topics: Birth Weight; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Injections, In | 1973 |
Phenobarbital effect on serum bilirubin levels in underweight infants.
Topics: Bilirubin; Birth Weight; Diseases in Twins; Female; Gestational Age; Humans; Infant Nutrition Disord | 1973 |
[Prevention of newborn infant hyperbilirubinemia by use of drugs. 8. Recommendation for the use of prevention in combination with a screening test for prognosis].
Topics: Birth Weight; Female; Gestational Age; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, | 1973 |
Relative roles of phototherapy and phenobarbitone in treatment of nonhaemolytic neonatal jaundice.
Topics: Bilirubin; Birth Weight; Hematocrit; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Jaundice, | 1973 |
Disappearance from the newborn of circulating prenatally administered phenobarbital.
Topics: Birth Weight; Female; Fetus; Gestational Age; Half-Life; Humans; Hypertension; Infant, Newborn; Kine | 1973 |
Induction of drug metabolizing enzyme activities in the human fetus and in the newborn infant.
Topics: Birth Weight; Child; Diazepam; Enzyme Induction; Female; Fetus; Gestational Age; Humans; Infant, New | 1973 |
Late presentation of drug withdrawal symptoms in newborns.
Topics: Birth Weight; Camphor; Diazepam; Female; Gestational Age; Heroin Dependence; Humans; Infant; Infant, | 1974 |
[Therapeutic and preventive values of phenobarbital in the prevention and treatment of neonatal jaundice].
Topics: ABO Blood-Group System; Administration, Oral; Bilirubin; Birth Weight; Blood Group Incompatibility; | 1971 |
Barbiturate treatment of neonatal icterus.
Topics: Bilirubin; Birth Weight; Factor V; Factor VII; Hematocrit; Humans; Infant, Newborn; Infant, Prematur | 1972 |
Sequential trial of effect of phenobarbitone on serum bilirubin of preterm infants.
Topics: Age Factors; Bilirubin; Birth Weight; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prem | 1972 |
Narcotic withdrawal in the newborn.
Topics: Birth Weight; Chlorpromazine; Cocaine; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, N | 1972 |
Observations on heroin and methadone withdrawal in the newborn.
Topics: Adolescent; Adult; Apgar Score; Birth Weight; Female; Heroin; Humans; Infant, Newborn; Infant, Newbo | 1971 |
Phenobarbitone in neonatal jaundice.
Topics: Bilirubin; Birth Weight; China; Exchange Transfusion, Whole Blood; Female; Humans; India; Infant, Ne | 1971 |
[The influence of short time phenobarbital treatment on neonatal jaundice].
Topics: Age Factors; Bilirubin; Birth Weight; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice | 1971 |
[Results of treatment of hypertrophic pyloric stenosis in 351 infants from 1945-1964].
Topics: Age Factors; Atropine; Birth Weight; Congenital Abnormalities; Diagnosis, Differential; Diet Therapy | 1970 |
Phototherapy of jaundice 1969.
Topics: ABO Blood-Group System; Adolescent; Age Factors; Bilirubin; Birth Weight; Blood Group Incompatibilit | 1970 |
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, | 1971 |