Page last updated: 2024-11-02

phenobarbital and Bilirubinemia

phenobarbital has been researched along with Bilirubinemia in 144 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"Several mutations of bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) have been reported in patients with unconjugated hyperbilirubinemia."8.12Gilbert or Crigler-Najjar syndrome? Neonatal severe unconjugated hyperbilirubinemia with P364L UGT1A1 homozygosity. ( Civeriati, D; Cozzi, L; Degrassi, I; Nebbia, G; Nuti, F; Paolella, G, 2022)
"Crigler-Najjar syndrome (CN) type II is a congenital disease with unconjugated hyperbilirubinemia due to a deficiency of uridine 5'-diphospho-glucuronosyltransferase 1A1."7.83Reduction of hyperbilirubinemia with hypericum extract (St. John's Wort) in a patient with Crigler-Najjar syndrome type II. ( Hammann, F; Haschke, M; Krähenbühl, S; Kummer, O, 2016)
"Long-term phenobarbital treatment (2 mg/kg body weight/day) permanently reduced hyperbilirubinemia in a patient with congenital non-spherocytic hemolytic anemia due to erythrocyte glucose phosphate isomerase deficiency."7.66Successful long-term phenobarbital therapy of hyperbilirubinemia in congenital hemolytic anemia due to glucose phosphate isomerase deficiency. ( Schröter, W, 1980)
" From 22 newborns with non-hemolytic unconjugated hyperbilirubinemia 11 were treated with 7."7.65[Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. ( Gladtke, E; Heimann, G; Roth, B, 1977)
" Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal."7.65Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975)
"Unconjugated hyperbilirubinemia as occurs in Gunn rats did not affect the plasma disappearance of sulfobromophthalein (BSP) or indocyanine green (ICG)."7.65Plasma disappearance of sulfobromophthalein or indocyanine green in unconjugated hyperbilirubinemia. ( Wise, KJ; Yeary, RA, 1975)
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"Several mutations of bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) have been reported in patients with unconjugated hyperbilirubinemia."4.12Gilbert or Crigler-Najjar syndrome? Neonatal severe unconjugated hyperbilirubinemia with P364L UGT1A1 homozygosity. ( Civeriati, D; Cozzi, L; Degrassi, I; Nebbia, G; Nuti, F; Paolella, G, 2022)
" Patients with Crigglar-Najjar syndrome type II respond to phenobarbital therapy which decreases their chances of getting bilirubinemia by 60-70% in 3 weeks."3.88Crigler-Najjar Syndrome Type II Diagnosed in a Patient with Jaundice Since Birth. ( Ameer, A; Attiq, H; Imran, M; Liaqat, A; Shahid, A, 2018)
"Crigler-Najjar syndrome (CN) type II is a congenital disease with unconjugated hyperbilirubinemia due to a deficiency of uridine 5'-diphospho-glucuronosyltransferase 1A1."3.83Reduction of hyperbilirubinemia with hypericum extract (St. John's Wort) in a patient with Crigler-Najjar syndrome type II. ( Hammann, F; Haschke, M; Krähenbühl, S; Kummer, O, 2016)
"Long-term phenobarbital treatment (2 mg/kg body weight/day) permanently reduced hyperbilirubinemia in a patient with congenital non-spherocytic hemolytic anemia due to erythrocyte glucose phosphate isomerase deficiency."3.66Successful long-term phenobarbital therapy of hyperbilirubinemia in congenital hemolytic anemia due to glucose phosphate isomerase deficiency. ( Schröter, W, 1980)
"Salicylamide glucuronide (SAMG) in 0-6 and 6-12 hours-urine specimens was determined after oral administration of salicylamide in 7 normal volunteers (NV), in 51 cases of various liver diseases and hyperbilirubinemias, and in 19 cases after drug administration, to predict the in vivo drug metabolism in man and its change by drugs."3.65Salycylamide glucuronide formation in liver disease and its change by drugs. ( Adachi, Y; Wakisaka, G; Yamamoto, T, 1975)
" From 22 newborns with non-hemolytic unconjugated hyperbilirubinemia 11 were treated with 7."3.65[Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. ( Gladtke, E; Heimann, G; Roth, B, 1977)
" Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal."3.65Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975)
"Unconjugated hyperbilirubinemia as occurs in Gunn rats did not affect the plasma disappearance of sulfobromophthalein (BSP) or indocyanine green (ICG)."3.65Plasma disappearance of sulfobromophthalein or indocyanine green in unconjugated hyperbilirubinemia. ( Wise, KJ; Yeary, RA, 1975)
""Kernicterus" is a term currently used to describe bilirrubin induced brain injury in the neuro-pathological studies."1.38[Neurological dysfunction induced by bilirrubin]. ( Campistol, J; Cazorla, AG; Cusí, V; Galvez, H; Iriondo, M; Málaga, I, 2012)
"Treatment with phenobarbital, which increased steady-state RcGshT mRNA by five- to sixfold, RcGshT polypeptide, and biliary GSH secretion by onefold in controls, had a smaller effect on steady-state RcGshT-mRNA level in EHBR (by 1."1.29Alterations in glutathione homeostasis in mutant Eisai hyperbilirubinemic rats. ( Cai, J; Horie, T; Kaplowitz, N; Kuhlenkamp, J; Lu, SC; Sun, WM; Takenaka, O; Takikawa, H; Yi, J, 1996)
"The role of S-oxidation in the toxic bioactivation of alpha-naphthylisothiocyanate (ANIT) was investigated."1.27Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate. ( Hanzlik, RP; Traiger, GJ; Vyas, KP, 1985)
"Phenobarbital treatment significantly reduced the level of unconjugated serum bilirubin in patients with acute hepatitis or Gilbert's syndrome, but without any difference within these two groups of patients."1.26Diagnosis of Gilbert's syndrome. Reliability of the caloric restriction and phenobarbital stimulation tests. ( Hardt, F; Juhl, E; Thomsen, HF, 1981)
"Phenobarbital alone has been useful, so far, in the treatment of cholesterol gallstones."1.25Barbituates and biliary function. ( Capron, JP; Erlinger, S, 1975)
" Dose-response curves can be derived for the parameters used for assessing dysfunction."1.25Metabolic alterations in organ function. ( Plaa, GL, 1975)

Research

Studies (144)

TimeframeStudies, this research(%)All Research%
pre-1990128 (88.89)18.7374
1990's6 (4.17)18.2507
2000's6 (4.17)29.6817
2010's3 (2.08)24.3611
2020's1 (0.69)2.80

Authors

AuthorsStudies
Ogawa, K1
Suzuki, H1
Hirohashi, T1
Ishikawa, T1
Meier, PJ1
Hirose, K1
Akizawa, T1
Yoshioka, M1
Sugiyama, Y1
Tukey, RH1
Strassburg, CP1
Johnson, DR2
Habeebu, SS1
Klaassen, CD2
Cozzi, L1
Nuti, F1
Degrassi, I1
Civeriati, D1
Paolella, G1
Nebbia, G1
Liaqat, A1
Shahid, A1
Attiq, H1
Ameer, A1
Imran, M1
Kummer, O1
Hammann, F1
Haschke, M1
Krähenbühl, S1
Garg, PK1
Kumar, A1
Teckchandani, N1
Hadke, NS1
Campistol, J1
Galvez, H1
Cazorla, AG1
Málaga, I1
Iriondo, M1
Cusí, V1
Yaffe, SJ4
Levy, G3
Matsuzawa, T1
Baliah, T1
DeLeon, A1
Gartner, LM1
Arias, IM2
Stetsenko, GI1
Fürnkranz, H1
Rosenkranz, A1
Firinu, C1
Meloni, T1
Milia, S1
Virdis, P1
Lo Dico, G1
Stoppelli, I1
Iwańczak, F1
Prandota, J1
Thomsen, HF1
Hardt, F1
Juhl, E1
Schröter, W1
Beckh, K1
Oguro, T1
Kaneko, E1
Kaneko, Y1
Numazawa, S1
Imaoka, S1
Funae, Y1
Mikami, T1
Yoshida, T1
Lu, SC1
Cai, J1
Kuhlenkamp, J1
Sun, WM1
Takikawa, H1
Takenaka, O1
Horie, T2
Yi, J1
Kaplowitz, N1
Horio, F1
Ciotti, M1
Werlin, SL1
Owens, IS1
Lee, WS1
McKiernan, PJ1
Beath, SV1
Preece, MA1
Baty, D1
Kelly, DA1
Burchell, B1
Clarke, DJ1
Mechkov, G1
Dimov, D1
Iordanova, Iu1
Adachi, Y4
Wakisaka, G1
Yamamoto, T4
Kuwahara, I1
Plöchl, E1
Hohenwallner, W2
Capron, JP1
Erlinger, S1
Porter, RJ1
Layzer, RB1
Gonciarz, Z1
Czarnecka, K1
Schenk, J1
Gentile, S1
Porcellini, M1
Leo, C1
Foglia, F1
Lathe, GH1
Loginov, AS1
Blok, IuE1
Roth, B1
Heimann, G1
Gladtke, E1
Schmeisser, W1
Eggstein, M1
Maulbetsch, R1
Dölle, W1
McCrae, WM1
Fevery, J2
Mentsel', K1
Shambakh, K1
Grabosh, E1
Berk, PD1
Martin, JF1
Blaschke, TF1
Scharschmidt, BF1
Plotz, PH1
Plaa, GL3
Garrettson, LK1
Davis, DR1
Yearly, RA1
Dhumeaux, D1
Berthelot, P1
Yeary, RA1
Wise, KJ1
Schambach, K1
Menzel, K2
Bode, JC1
Traiger, GJ1
Vyas, KP1
Hanzlik, RP1
Ahmed, AE1
Grissom, M1
el-Azhary, R1
Haque, A1
Boor, PJ1
Costanzi, J1
Rayburn, W1
Donn, S1
Piehl, E1
Compton, A1
Greim, H1
Thompson, RP1
Williams, R1
Maurer, HM3
Wolff, JA1
Finster, M1
Poppers, PJ1
Pantuck, E1
Kuntzman, R1
Conney, AH1
Trolle, D1
De Oya, JC3
Del Río, A3
Noya, M3
Villanueva, A2
Black, M4
Sherlock, S1
Parker, D1
Jacobson, J1
Billing, BH2
Carson, ER1
Wilson, JT3
Chevrel, B1
Hecht, Y1
Sisson, TR1
Maisels, MJ1
Tanaka, S1
Sanbe, K1
Kamegaya, K1
Oda, M1
Okazaki, I1
Iwasaki, Y1
Török, J1
Eriksson, M1
Thaler, MM1
Halpin, TF1
Jones, AR1
Bishop, HL1
Lerner, S1
Kintzel, HW5
Schwarze, R4
Hinkel, GK4
Händel, A2
Gmyrek, D3
Weh, L2
Kalz, M1
Bunke, H2
Cario, WR2
Lindenau, E1
Neumann, R1
Pietsch, I1
Scigalla, P1
Sima, K1
Syllm-Rapoport, I2
Grauaug, A1
Hosková, A2
Hlavon, J1
Páleníková, K1
Pátková, A1
Hodr, R2
Plesingerová, I2
Senkárcinová, V2
Ballow, M1
Margolis, CZ1
Schachtel, B1
Hsia, YE1
Windorfer, A2
Mihailova, K1
Pringsheim, W1
Daberkow, H1
Läuter, J1
Saworra, H1
Wong, YK1
Wood, BS1
Czerny, M1
Hohenauer, L1
Perona, G1
Corrocher, R1
Frezza, M1
Falezza, GC1
Cellerino, R1
Tiribelli, C1
Fusaro, A1
De Sandre, G1
Shakun, NP1
Oleinik, AN1
Caroli, J1
Nusinovici, V1
Amar, AB1
Lévy, VG1
Rubaltelli, FF1
Espinoza, J1
Barnafi, L1
Schnaidt, E1
Ciampolini, M1
Bougleux, T1
Hazeltine, W1
Lucey, JF2
Wennberg, RP1
Valdes, OS2
Shumway, CN2
Draper, DA1
Hossaini, AA1
Hirayama, C1
Stern, L4
Scholz, E1
Chaudhuri, VP1
Ghai, OP1
Harris, RC1
Yeung, CY2
Tilz, GP1
Vazzoler, G1
Forabosco, A1
Muz, G1
Svirsky, S1
Tomer, A1
Tam, LS1
Chan, A1
Lee, KH1
Vaisman, S2
Galecio, R1
Erazo, R1
Kunzack, H1
Horký, J1
Grasso, P1
Golberg, L1
Ebensperger, I1
Hering, E1
Severi, F1
Marchi, A1
Colombo, A1
Di Marco, A1
Ehrnebo, M1
Agurell, S1
Jalling, B1
Boréus, LO1
Halbrecht, I1
Vardi, V1
Menashe, R1
Crigler, JF1
Cao, A2
Fracassini, F2
Falorni, A2
Mastrantonio, P1
Murano, G1
Di Toro, R1
Khanna, NN1
Theile, H1
Reich, J1
Bereitter, E1
Berger, H1
Vest, M1
Signer, E1
Weisser, K1
Olafsson, A1
Zwacka, G1
Frenzel, J1
Fagiolo, U1
Farini, R1
Cartei, G1
Naccarato, R1
Lüders, D1
Catz, CS1
Khanna, N1
MacLeod, P1
Ferrero, AM1
Marca, L1
Pani, C1
Satolli, E1
Airaghi, M1
Nicolini, A1
Berglund, G1
Hansson, L1
Vikgren, P1
Whelton, MJ1
Krustev, LP1
Roberts, RJ2

Reviews

18 reviews available for phenobarbital and Bilirubinemia

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
[Phenobarbital in the treatment of hepatic disorders of bilirubin metabolism].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1979, May-28, Volume: 34, Issue:22

    Topics: Bilirubin; Cholestasis; Drug Evaluation; Humans; Hyperbilirubinemia; Jaundice, Chronic Idiopathic; L

1979
Neonatal bilirubin metabolism in relation to jaundice.
    Clinics in endocrinology and metabolism, 1976, Volume: 5, Issue:1

    Topics: Agar; Animals; Bilirubin; Breast Feeding; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaund

1976
Developmental pharmacology: a review of its application to clinical and basic science.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental;

1972
Bilirubin; on understanding and influencing its metabolism in the newborn infant.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:2

    Topics: Bile Pigments; Bilirubin; Exchange Transfusion, Whole Blood; Female; Fetus; Heme; Humans; Hyperbilir

1972
[Induction of UDP glucuronyltransferase and its application to treatment of indirect hyperbilirubinemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:9

    Topics: Animals; Barbiturates; Bilirubin; Cyclohexanes; Enzyme Induction; Glucuronates; Hexosyltransferases;

1972
[Advances in the treatment of jaundice in the department of internal medicine].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Bilirubin; Cholestasis; Female; Humans; Hyperbilirubinemia; Jaundice

1972
[Enzyme induction in the liver--its mechanism and clinical significance].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:9

    Topics: Animals; Cushing Syndrome; DNA; Dogs; Drug Synergism; Enzyme Induction; Enzyme Repression; Glucocort

1972
[Hyperbilirubinemia in premature infants during 1948-1973 (evaluation and therapy of physiological jaundice in newborn infants of low birth weight during the past 25 years)].
    Orvosi hetilap, 1973, Aug-05, Volume: 114, Issue:31

    Topics: Adrenal Cortex Hormones; Birth Weight; Brain Diseases; Exchange Transfusion, Whole Blood; Gestationa

1973
Drug metabolism in the newborn.
    Annual review of medicine, 1973, Volume: 24

    Topics: Animals; Animals, Newborn; Enzyme Induction; Fetus; Humans; Hyperbilirubinemia; Hyperbilirubinemia,

1973
Phenobarbital in the perinatal period.
    Pediatrics, 1969, Volume: 43, Issue:3

    Topics: Animals; Animals, Newborn; Bilirubin; Chemical and Drug Induced Liver Injury; Drug Antagonism; Drug

1969
DDT and juvenile jaundice.
    Clinical toxicology, 1971, Volume: 4, Issue:1

    Topics: Animals; Breast Feeding; DDT; Enzyme Induction; Female; Humans; Hyperbilirubinemia; Infant Food; Inf

1971
Changing concepts regarding exchange transfusions and neonatal jaundice.
    Clinical obstetrics and gynecology, 1971, Volume: 14, Issue:2

    Topics: Bilirubin; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Hemoglobins; Humans;

1971
What to do when the infant is jaundiced.
    Medical times, 1971, Volume: 99, Issue:11

    Topics: Animals; Bilirubin; Diagnosis, Differential; Erythroblastosis, Fetal; Erythropoiesis; Exchange Trans

1971
[Enzyme induction therapy of liver diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29, Issue:10

    Topics: Adrenal Cortex Hormones; Anabolic Agents; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Gluc

1971
The control of hyperbilirubinemia in the newborn.
    Clinical obstetrics and gynecology, 1971, Volume: 14, Issue:3

    Topics: Animals; Bilirubin; Enzyme Induction; Exchange Transfusion, Whole Blood; Food; Growth Disorders; Hum

1971
Neonatal hyperbilirubinemia--some new approaches--.
    Indian pediatrics, 1971, Volume: 8, Issue:11

    Topics: Animals; Bilirubin; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Orotic A

1971
The newer hyperbilirubinemias.
    Disease-a-month : DM, 1968

    Topics: ABO Blood-Group System; Anemia, Hemolytic; Antigen-Antibody Reactions; Bilirubin; Biological Transpo

1968

Trials

4 trials available for phenobarbital and Bilirubinemia

ArticleYear
Antenatal phenobarbital and bilirubin metabolism in the very low birth weight infant.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:6

    Topics: Bilirubin; Delivery, Obstetric; Female; Humans; Hyperbilirubinemia; Infant, Low Birth Weight; Infant

1988
Controlled clinical trial of phenobarbital and-or light in reducing neonatal hyperbilirubinemia in a predominantly Negro population.
    The Journal of pediatrics, 1971, Volume: 79, Issue:6

    Topics: Bilirubin; Birth Weight; Black or African American; Clinical Trials as Topic; Humans; Hyperbilirubin

1971
[The effect of phenobarbitol treatment on hyperbilirubinemia and albumin binding capacity in premature infants].
    Zeitschrift fur arztliche Fortbildung, 1971, Oct-01, Volume: 65, Issue:19

    Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Enzyme Induction; Exchange Transfusion, Whole Blo

1971
A double blind study of the effect of phenobarbitone on neonatal hyperbilirubinaemia and frequency of exchange transfusion.
    Acta paediatrica Scandinavica, 1970, Volume: 59, Issue:6

    Topics: Bilirubin; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, N

1970

Other Studies

122 other studies available for phenobarbital and Bilirubinemia

ArticleYear
Characterization of inducible nature of MRP3 in rat liver.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:3

    Topics: 1-Naphthylisothiocyanate; Animals; Anion Transport Proteins; ATP-Binding Cassette Transporters; Bili

2000
Increase in bile flow and biliary excretion of glutathione-derived sulfhydryls in rats by drug-metabolizing enzyme inducers is mediated by multidrug resistance protein 2.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 66, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Benzopyrenes; Bile; Biliary Tract; Carrier Proteins; Dru

2002
Gilbert or Crigler-Najjar syndrome? Neonatal severe unconjugated hyperbilirubinemia with P364L UGT1A1 homozygosity.
    Italian journal of pediatrics, 2022, Apr-18, Volume: 48, Issue:1

    Topics: Bilirubin; Crigler-Najjar Syndrome; Female; Gilbert Disease; Glucuronosyltransferase; Humans; Hyperb

2022
Crigler-Najjar Syndrome Type II Diagnosed in a Patient with Jaundice Since Birth.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018, Volume: 28, Issue:10

    Topics: Adolescent; Crigler-Najjar Syndrome; Female; Gilbert Disease; Glucuronosyltransferase; Humans; Hyper

2018
Reduction of hyperbilirubinemia with hypericum extract (St. John's Wort) in a patient with Crigler-Najjar syndrome type II.
    British journal of clinical pharmacology, 2016, Volume: 81, Issue:5

    Topics: Adult; Area Under Curve; Bilirubin; Crigler-Najjar Syndrome; Cytochrome P-450 CYP3A; Enzyme Inductio

2016
Hereditary spherocytosis coexisting with Gilbert's syndrome: a diagnostic dilemma.
    Singapore medical journal, 2008, Volume: 49, Issue:11

    Topics: Adolescent; Bilirubin; Caloric Restriction; Diagnosis, Differential; Gilbert Disease; Humans; Hyperb

2008
[Neurological dysfunction induced by bilirrubin].
    Neurologia (Barcelona, Spain), 2012, Volume: 27, Issue:4

    Topics: Age of Onset; Autopsy; Electroencephalography; Evoked Potentials, Auditory; Exchange Transfusion, Wh

2012
Enhancement of glucuronide-conjugating capacity in a hyperbilirubinemic infant due to apparent enzyme induction by phenobarbital.
    The New England journal of medicine, 1966, Dec-29, Volume: 275, Issue:26

    Topics: Animals; Enzyme Induction; Female; Glucuronidase; Humans; Hyperbilirubinemia; In Vitro Techniques; I

1966
Therapy by enzyme induction.
    The New England journal of medicine, 1966, Dec-29, Volume: 275, Issue:26

    Topics: Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Phenobarbital; Tr

1966
The effect of phenobarbital on hyperbilirubinemia in glucuronyl transferase deficient rats.
    The Journal of laboratory and clinical medicine, 1967, Volume: 70, Issue:2

    Topics: Animals; Bile; Chromatography, Paper; Female; Glucosyltransferases; Glucuronates; Histocytochemistry

1967
[Differentiated treatment of benign hyperbilirubinemia at the Truskavets health resort].
    Vrachebnoe delo, 1984, Issue:9

    Topics: Adolescent; Adult; Baths; Diagnosis, Differential; Female; Health Resorts; Humans; Hyperbilirubinemi

1984
[Pediatric aspects of success and failure of anti-D-prophylaxis].
    Wiener medizinische Wochenschrift (1946), 1983, Dec-31, Volume: 133, Issue:23-24

    Topics: Abortion, Spontaneous; Adult; Bilirubin; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood;

1983
[Prenatal prevention of hyperbilirubinemia due to G6PD deficiency].
    Minerva ginecologica, 1983, Volume: 35, Issue:5

    Topics: Adult; Female; Fetal Diseases; Glucosephosphate Dehydrogenase Deficiency; Humans; Hyperbilirubinemia

1983
[Gilbert's syndrome. Diagnostic difficulties and successful use of the luminal test].
    Pediatria polska, 1980, Volume: 55, Issue:12

    Topics: Adolescent; Bilirubin; Child; Diagnosis, Differential; Female; Gilbert Disease; Humans; Hyperbilirub

1980
Diagnosis of Gilbert's syndrome. Reliability of the caloric restriction and phenobarbital stimulation tests.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Bilirubin; Diagnosis, Differential; Energy Intake; Fasting; Female

1981
Successful long-term phenobarbital therapy of hyperbilirubinemia in congenital hemolytic anemia due to glucose phosphate isomerase deficiency.
    European journal of pediatrics, 1980, Volume: 135, Issue:1

    Topics: Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Congenital Nonspherocytic; Child; Child, Preschool

1980
[Does hyperbilirubinemia in Meulengracht disease (Gilbert syndrome) need treatment?].
    Der Internist, 1994, Volume: 35, Issue:11

    Topics: Adult; Bilirubin; Female; Gilbert Disease; Humans; Hyperbilirubinemia; Male; Phenobarbital

1994
Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis).
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Hyperbilirubinemia; Immunoblotting; Liver; Male; Microsomes

1996
Alterations in glutathione homeostasis in mutant Eisai hyperbilirubinemic rats.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:1

    Topics: Analysis of Variance; Animals; Bile; Body Weight; Cysteine; Female; Glutamate-Cysteine Ligase; Gluta

1996
The role of microsomal beta-glucuronidase in ascorbic acid biosynthesis stimulated by xenobiotics in rats.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:1

    Topics: Animals; Ascorbic Acid; Blotting, Northern; Glucuronidase; Heterozygote; Homozygote; Hyperbilirubine

1997
Delayed response to phenobarbital treatment of a Crigler-Najjar type II patient with partially inactivating missense mutations in the bilirubin UDP-glucuronosyltransferase gene.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:2

    Topics: Bilirubin; Crigler-Najjar Syndrome; Fluid Therapy; Glucuronosyltransferase; Humans; Hyperbilirubinem

1999
Bile bilirubin pigment analysis in disorders of bilirubin metabolism in early infancy.
    Archives of disease in childhood, 2001, Volume: 85, Issue:1

    Topics: Bile Pigments; Bilirubin; Chromatography, High Pressure Liquid; Crigler-Najjar Syndrome; Diagnosis,

2001
Role of rat multidrug resistance protein 2 in plasma and biliary disposition of dibromosulfophthalein after microsomal enzyme induction.
    Toxicology and applied pharmacology, 2002, Apr-01, Volume: 180, Issue:1

    Topics: Animals; Bile; Disease Models, Animal; Drug Resistance, Multiple; Enzyme Induction; Hyperbilirubinem

2002
[Proceedings: Serum gamma-glutamyl tranapeptidase activity after the induction and inhibition of liver microsomal enzymes in nonconjugated hyperbilirubinemia].
    Vutreshni bolesti, 1976, Volume: 15, Issue:1

    Topics: Enzyme Induction; Enzyme Repression; gamma-Glutamyltransferase; Gilbert Disease; Humans; Hyperbiliru

1976
Salycylamide glucuronide formation in liver disease and its change by drugs.
    Gastroenterologia Japonica, 1975, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Barbiturates; Bilirubin; Child; Female; Gilbert Disease; Glucuronates; Hepa

1975
Effects of bucolome and related barbiturate derivatives on the displacement of bilirubin from plasma albumin in vivo and in vitro.
    Gastroenterologia Japonica, 1979, Volume: 14, Issue:5

    Topics: Animals; Barbiturates; Bilirubin; Gilbert Disease; Hyperbilirubinemia; In Vitro Techniques; Male; Ph

1979
[Treatment of Crigler-Najjar's congenital familial non-hemolytic jaundice with kernicterus].
    Wiener medizinische Wochenschrift (1946), 1978, Feb-15, Volume: 128, Issue:3

    Topics: Crigler-Najjar Syndrome; Developmental Disabilities; Epilepsy; Female; Humans; Hyperbilirubinemia; H

1978
Barbituates and biliary function.
    Digestion, 1975, Volume: 12, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Bile; Bile Acids and Salts; Biliary Tract; Bilirubin; Cholelithi

1975
Plasma albumin concentration and diphenylhydantoin binding in man.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Protein Electrophoresis; Blood-Brain Barrier; Chromatography

1975
[Hyperbilirubinemias; diagnostic and therapeutic aspects].
    Fortschritte der Medizin, 1979, Feb-01, Volume: 97, Issue:5

    Topics: Adult; Bilirubin; Diagnosis, Differential; Gilbert Disease; Hemolysis; Humans; Hyperbilirubinemia; I

1979
[Influence of phenobarbital on hyperbilirubinemia caused by nicotinic acid and rifamycin--SV in healthy subjects].
    Bollettino della Societa italiana di biologia sperimentale, 1979, Nov-15, Volume: 55, Issue:21

    Topics: Adult; Female; Humans; Hyperbilirubinemia; Male; Nicotinic Acids; Phenobarbital; Rifamycins

1979
[Differential diagnosis and treatment of functional nonconjugated hyperbilirubinemias].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Diagnosis, Differential; Female; Humans; Hyperbilirubinemia; Male; Middle Aged; P

1977
[Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)].
    Padiatrie und Padologie, 1977, Volume: 12, Issue:4

    Topics: Bilirubin; Female; Glucaric Acid; Humans; Hyperbilirubinemia; Infant, Newborn; Male; Phenobarbital;

1977
[A case of benign recurring intrahepatic cholestasis (Tygstrup-Summerskill and Walshe syndrome)].
    Schweizerische medizinische Wochenschrift, 1977, Nov-12, Volume: 107, Issue:45

    Topics: Adult; Alkaline Phosphatase; Biopsy; Cholestasis; Cholestyramine Resin; Diet Therapy; Humans; Hyperb

1977
Kernicterus in the newborn.
    Nursing times, 1976, Jul-15, Volume: 72, Issue:28

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Kernicterus; Phenobarbital; Phototherapy

1976
Conjugation of bilirubin--pathophysiological aspects.
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1

    Topics: Bilirubin; Fasting; Gilbert Disease; Glutethimide; Hyperbilirubinemia; Nicotinic Acids; Obesity; Phe

1976
[Prevention and conservative treatment of transitory hyperbilirubinemia in full-term and premature infants].
    Voprosy okhrany materinstva i detstva, 1975, Volume: 20, Issue:1

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases;

1975
Unconjugated hyperbilirubinemia. Physiologic evaluation and experimental approaches to therapy.
    Annals of internal medicine, 1975, Volume: 82, Issue:4

    Topics: Adult; Albumins; Animals; Bilirubin; Crigler-Najjar Syndrome; Ethosuximide; Female; Gilbert Disease;

1975
Metabolic alterations in organ function.
    Journal - Association of Official Analytical Chemists, 1975, Volume: 58, Issue:4

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Dogs; Dose-Response Relationship

1975
Phenobarbital disposition in the neonate.
    Addictive diseases, 1975, Volume: 2, Issue:1-2

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Seizures; S

1975
Bilirubin binding to hepatic Y and Z protein (ligandin): tissue bilirubin concentrations in phenobarbital treated Gunn rats (38466).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:1

    Topics: Adipose Tissue; Animals; Bilirubin; Brain; Cytoplasm; Hyperbilirubinemia; Kidney; Liver; Lung; Male;

1975
Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep.
    Gastroenterology, 1975, Volume: 69, Issue:4

    Topics: Adult; Animals; Bilirubin; Female; Humans; Hyperbilirubinemia; Liver; Mutation; Phenobarbital; Sheep

1975
Plasma disappearance of sulfobromophthalein or indocyanine green in unconjugated hyperbilirubinemia.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:1

    Topics: Animals; Bile Ducts; Bilirubin; Female; Genotype; Hyperbilirubinemia; Indocyanine Green; Jaundice; K

1975
[Clinical experiences using phenobarbital in the prevention of hyperbilirubinemia in mature newborn infants in a controlled study].
    Zeitschrift fur arztliche Fortbildung, 1975, May-15, Volume: 69, Issue:10

    Topics: Bilirubin; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Humans; Hyperbilirubinemia

1975
[The therapeutic possibilities in Gilbert's disease].
    Deutsche medizinische Wochenschrift (1946), 1992, Oct-02, Volume: 117, Issue:40

    Topics: Combined Modality Therapy; Gilbert Disease; Glucose; Humans; Hyperbilirubinemia; Phenobarbital; Ultr

1992
Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate.
    Chemico-biological interactions, 1985, Volume: 52, Issue:3

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Aminopyrine; Animals; Bilirubin; Biotransformation;

1985
Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Chemical and Drug Induced Liver In

1987
[Therapeutic possibilities using the induction of drug reducing enzymes].
    Deutsche medizinische Wochenschrift (1946), 1970, Oct-23, Volume: 95, Issue:43

    Topics: Animals; Dicumarol; Electron Transport Complex IV; Enzyme Induction; Enzyme Therapy; Extracellular S

1970
Jaundice of the newborn and phenobarbitone.
    Lancet (London, England), 1971, Jan-16, Volume: 1, Issue:7690

    Topics: Birth Weight; Brain Diseases; Erythroblastosis, Fetal; Female; Humans; Hyperbilirubinemia; Infant, N

1971
Treatment of chronic intrahepatic cholestasis with phenobarbitone.
    Lancet (London, England), 1967, Sep-23, Volume: 2, Issue:7517

    Topics: Aged; Bilirubin; Cholestasis; Enzyme Induction; Female; Humans; Hyperbilirubinemia; Liver Function T

1967
Reduction in concentration of total serum-bilirubin in offspring of women treated with phenobarbitone during pregnancy.
    Lancet (London, England), 1968, Jul-20, Volume: 2, Issue:7560

    Topics: Bilirubin; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Maternal-Fetal Exchange; Phenobarbit

1968
Decrease of total serum-bilirubin concentration in newborn infants after phenobarbitone treatment.
    Lancet (London, England), 1968, Sep-28, Volume: 2, Issue:7570

    Topics: Bilirubin; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Liver; Maternal-

1968
Phenobarbitone in posthepatitic unconjugated hyperbilirubinaemia.
    Lancet (London, England), 1970, Sep-05, Volume: 2, Issue:7671

    Topics: Adult; Hepatitis; Humans; Hyperbilirubinemia; Male; Phenobarbital

1970
Treatment of Gilbert's syndrome with phenobarbitone.
    Lancet (London, England), 1970, Jun-27, Volume: 1, Issue:7661

    Topics: Adolescent; Adult; Bilirubin; Enzyme Induction; Female; Glucosyltransferases; Glutathione; Humans; H

1970
Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia.
    Clinical science and molecular medicine, 1974, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Anemia, Hemolytic; Bilirubin; Carbon Radioisotopes; Child; Female; Glucuronosyltr

1974
[Neonatal icterus due to hepatic immaturity].
    La Presse medicale, 1971, Apr-21, Volume: 79, Issue:20

    Topics: Adrenocorticotropic Hormone; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant,

1971
Phenobarbital and neonatal jaundice. The need for more knowledge.
    Clinical pediatrics, 1971, Volume: 10, Issue:12

    Topics: Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Phenobarbital; Pregnancy; S

1971
Neonatal hyperbilirubinemia.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Acidosis; Agar; Anemia, Hemolytic; Antibodies; Bilirubin; Blood Group Incompatibility; Blood Transfu

1972
Prophylaxis of neonatal hyperbilirubinemia with phenobarbital.
    Obstetrics and gynecology, 1972, Volume: 40, Issue:1

    Topics: ABO Blood-Group System; Bilirubin; Birth Weight; Erythroblastosis, Fetal; Female; Gestational Age; H

1972
[Prevention of transitory hyperbilirubinemia of the premature and mature newborn infants and of the hemolytic disease of the newborn by an enzyme induction combination: phenobarbital-nikethamide].
    Schweizerische medizinische Wochenschrift, 1972, Sep-23, Volume: 102, Issue:38

    Topics: Bilirubin; Enzyme Induction; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Hum

1972
[Prevention of hyperbilirubinemia in premature infants using a combination of two enzyme inductors: phenobarbitol and nikethamide].
    Das Deutsche Gesundheitswesen, 1972, Sep-28, Volume: 27, Issue:39

    Topics: Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Premature; Infant, Premature,

1972
[Drug prevention of hyperbilirubinemia in newborn infants. 5. Cumulative effect of the combination of the inductors phenobarbital and nikethamide].
    Das Deutsche Gesundheitswesen, 1972, Nov-23, Volume: 27, Issue:47

    Topics: Drug Combinations; Drug Synergism; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Dis

1972
The management of jaundice in the newborn.
    The Medical journal of Australia, 1972, Aug-12, Volume: 2, Issue:7

    Topics: Agar; Diagnosis, Differential; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; G

1972
[Phenobarbital in the newborn jaundice].
    Ceskoslovenska pediatrie, 1973, Volume: 28, Issue:1

    Topics: Administration, Oral; Humans; Hyperbilirubinemia; Infant, Newborn; Injections, Intramuscular; Jaundi

1973
[Phenobarbital and hyperbilirubinemia in newborn infants with low birth weight (1)].
    Ceskoslovenska pediatrie, 1973, Volume: 28, Issue:5

    Topics: Administration, Oral; Birth Weight; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Injections;

1973
Progressive familial intrahepatic cholestasis.
    Pediatrics, 1973, Volume: 51, Issue:6

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; C

1973
[Prevention of toxic hyperbilirubinemia in premature and mature newborn infants by use of an enzyme-inducing combination: phenobarbital-nikethamide].
    Helvetica paediatrica acta, 1973, Volume: 30

    Topics: Drug Synergism; Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Dise

1973
[Does drug therapy increase the dangers of bilirubin encephalopathy during the newborn period?].
    Deutsche medizinische Wochenschrift (1946), 1973, Jun-22, Volume: 98, Issue:25

    Topics: Ampicillin; Bilirubin; Blood; Carbenicillin; Cephalothin; Child, Preschool; Colistin; Diazepam; Eryt

1973
[Effect of various drugs on serum bilirubin level in newborn infants].
    Padiatrie und Padologie, 1973, Volume: 8, Issue:3

    Topics: Bilirubin; Diazepam; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Meproba

1973
[Phenobarbital and hyperbilirubinemia of newborn infants with low birth weight. II].
    Ceskoslovenska pediatrie, 1973, Volume: 28, Issue:7

    Topics: Birth Weight; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Injections, In

1973
[Prevention of newborn infant hyperbilirubinemia by use of drugs. 8. Recommendation for the use of prevention in combination with a screening test for prognosis].
    Kinderarztliche Praxis, 1973, Volume: 41, Issue:4

    Topics: Birth Weight; Female; Gestational Age; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn,

1973
Relative roles of phototherapy and phenobarbitone in treatment of nonhaemolytic neonatal jaundice.
    Archives of disease in childhood, 1973, Volume: 48, Issue:9

    Topics: Bilirubin; Birth Weight; Hematocrit; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Jaundice,

1973
[A0 blood-group constellation and preventive use of phenobarbital in neonatal jaundice].
    Klinische Padiatrie, 1973, Volume: 185, Issue:2

    Topics: ABO Blood-Group System; Austria; Blood Group Incompatibility; Humans; Hyperbilirubinemia; Infant, Ne

1973
Phenobarbitone of jaundice in haemolytic patients.
    British journal of haematology, 1973, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Agglutinins; Anemia, Hemolytic; Autoantibodies; Bilirubin; Cold Temperature; Fema

1973
[Enzyme induction in newborn infants--principles of medicamentous prevention of hyperbilirubinemia].
    Zeitschrift fur arztliche Fortbildung, 1973, Jun-15, Volume: 67, Issue:12

    Topics: Animals; Enzyme Induction; Epinephrine; Female; Galactosidases; Glucagon; Gluconeogenesis; Humans; H

1973
[Effect of drugs on bilirubin metabolism in the treatment of jaundice].
    Vrachebnoe delo, 1973, Volume: 11

    Topics: Bilirubin; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Humans; Hyperbilirubine

1973
[Acholangic cholestatic hepatitis evolving towards xanthomatosis and cirrhosis].
    Annales de medecine interne, 1973, Volume: 124, Issue:11

    Topics: Bile Ducts; Bilirubin; Biopsy; Blood Proteins; Cholestasis; Female; Glutethimide; Hepatitis; Humans;

1973
[Proceedings: Icterus gravis with indirect bilirubin].
    Minerva pediatrica, 1973, Oct-27, Volume: 25, Issue:37

    Topics: Brain Diseases; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Humans; Hyperbil

1973
The effect of phenobarbital on intrahepatic cholestasis of pregnancy.
    American journal of obstetrics and gynecology, 1974, May-15, Volume: 119, Issue:2

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Pro

1974
[How harmless are modern methods of treating the physiologic jaundice of neonates? (author's transl)].
    Klinische Padiatrie, 1974, Volume: 186, Issue:1

    Topics: Diarrhea, Infantile; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant, Newborn;

1974
[Development of glycuronoconjugation in twins treated with barbiturates. Studies in vivo with the salicylamide test].
    Minerva pediatrica, 1974, Jul-28, Volume: 26, Issue:24

    Topics: Bilirubin; Female; Glucuronates; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Ma

1974
[Therapeutic reduction of the indirect serum bilirubin level through enzyme induction using phenobarbital (Luminal)].
    Der Internist, 1968, Apr-25, Volume: 9, Issue:3

    Topics: Bilirubin; Child; Enzyme Induction; Humans; Hyperbilirubinemia; Liver; Liver Cirrhosis; Phenobarbita

1968
Bilirubin metabolism in the newborn.
    Birth defects original article series, 1970, Volume: 6, Issue:2

    Topics: Animals; Bile Pigments; Bilirubin; Female; History of Medicine; Humans; Hyperbilirubinemia; Infant,

1970
Blood sugar changes in neonatal hyperbilirubinaemia and phenobarbitone therapy.
    Archives of disease in childhood, 1972, Volume: 47, Issue:252

    Topics: Blood Glucose; Enzyme Induction; Glucosephosphate Dehydrogenase; Humans; Hyperbilirubinemia; Infant,

1972
[Enzyme induction in hereditary spherocytosis using barbiturate].
    Medizinische Klinik, 1972, Feb-11, Volume: 67, Issue:6

    Topics: Abnormalities, Multiple; Anemia, Hemolytic, Congenital Nonspherocytic; Enzyme Induction; Female; Fol

1972
[Phenobarbital treatment of indirect hyperbilirubinemia states in various hepatic diseases].
    Revista clinica espanola, 1972, Mar-15, Volume: 124, Issue:5

    Topics: Administration, Oral; Hepatitis; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Liver C

1972
Light plus phenobarbital in the reduction of serum bilirubin.
    Pediatrics, 1972, Volume: 50, Issue:1

    Topics: Bilirubin; Humans; Hyperbilirubinemia; Infant, Newborn; Phenobarbital; Phototherapy

1972
[Treatment of hyperbilirubinemia of the newborn with phenobarbital].
    Minerva pediatrica, 1972, Jun-16, Volume: 24, Issue:22

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital

1972
[Treatment of post-hepatitis nonconjugated hyperbilirubinemia with phenobarbital].
    Prensa medica argentina, 1971, Mar-26, Volume: 58, Issue:4

    Topics: Adult; Hepatitis A; Humans; Hyperbilirubinemia; Male; Phenobarbital

1971
[Evaluation of phenobarbitone treatment in neonatal hyperbilirubinemia].
    Harefuah, 1971, Feb-15, Volume: 80, Issue:4

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases;

1971
Phenobarbitone prophylaxis for neonatal hyperbilirubinemia.
    Pediatrics, 1971, Volume: 48, Issue:3

    Topics: ABO Blood-Group System; Bilirubin; Blood Group Incompatibility; Female; Hong Kong; Humans; Hyperbili

1971
[Phenobarbital in neonatal jaundice].
    Ceskoslovenska pediatrie, 1971, Volume: 26, Issue:8

    Topics: Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Phenobarbital

1971
[Hyperbilirubinemia in the newborn and phenobarbital. I. Full term newborn infants].
    Revista chilena de pediatria, 1971, Volume: 42, Issue:4

    Topics: Female; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Male; Phenobarb

1971
Influence of phenobarbital on histological and biochemical changes in experimental intrahepatic cholestasis.
    Experimentelle Pathologie, 1971, Volume: 5, Issue:3

    Topics: Alkaline Phosphatase; Animals; Bilirubin; Cholestasis; Cholesterol; Female; Hyperbilirubinemia; Live

1971
[Hyperbilirubinemia in newborn infants and phenobarbital. II. Newborn infants of low weight].
    Revista chilena de pediatria, 1971, Volume: 42, Issue:5

    Topics: Female; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Premature, Diseases; Male; Phenobarbita

1971
[Effects of luminal treatment on neonatal hyperbilirubinemia in premature infants].
    La Pediatria, 1971, Volume: 79, Issue:3

    Topics: Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infan

1971
[Phenobarbital treatment of transitory non-hemolytic and non-conjugated neonatal hyperbilirubinemia. Results observed in a selected group of cases].
    La Clinica pediatrica, 1971, Volume: 53, Issue:9

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital

1971
[Synergistic effect of combined enzyme inductors (Phenobarbital and Nikethamide) on the bilirubin concentration in the serum of newborn infants].
    Das Deutsche Gesundheitswesen, 1971, Dec-16, Volume: 26, Issue:51

    Topics: Drug Synergism; Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Nikethamide; Phenobar

1971
Age differences in drug binding by plasma proteins: studies on human foetuses, neonates and adults.
    European journal of clinical pharmacology, 1971, Volume: 3, Issue:4

    Topics: Adult; Age Factors; Aging; Ampicillin; Azides; Bilirubin; Blood Proteins; Dialysis; Female; Fetus; F

1971
[The effect of phenobarbitone intake during pregnancy on the concentration of total serum bilirubin of the newborn].
    Harefuah, 1971, Jun-05, Volume: 80, Issue:12

    Topics: Bilirubin; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Phenobarbital; Pregnancy

1971
Caution with phenobarbital.
    Clinical pediatrics, 1971, Volume: 10, Issue:12

    Topics: Drug Interactions; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Phenobar

1971
Phenobarbital, hormones, and bilirubin.
    The Johns Hopkins medical journal, 1969, Volume: 125, Issue:5

    Topics: Bilirubin; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Phenobarbita

1969
[Phenobarbital in the treatment of hyperbilirubinemia of the newborn].
    La Pediatria, 1969, Volume: 77, Issue:1

    Topics: Bilirubin; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Infant, P

1969
[On the "rebound" of bilirubin in the newborn after exchange transfusion].
    La Pediatria, 1969, Volume: 77, Issue:5

    Topics: Bilirubin; Brain Diseases; Erythroblastosis, Fetal; Exchange Transfusion, Whole Blood; Female; Human

1969
[Experience in treatment of hyperbilirubinemia in the newborn with phenobarbital].
    Minerva pediatrica, 1970, Mar-24, Volume: 22, Issue:12

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases;

1970
Effect of phenobarbital on hyperbilirubinemia and glucuronide formation in newborns.
    American journal of diseases of children (1960), 1970, Volume: 120, Issue:1

    Topics: Bilirubin; Female; Glucuronates; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Disea

1970
[Effect of phenobarbital on the bilirubin level in premature infants].
    Helvetica paediatrica acta, 1970, Volume: 25, Issue:1

    Topics: Administration, Oral; Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Premature, Diseases; Inje

1970
Enzyme induction: introduction.
    Clinical science, 1970, Volume: 39, Issue:3

    Topics: Alkaline Phosphatase; Animals; Biliary Tract Diseases; Binding Sites; DDT; Enzyme Induction; Humans;

1970
Enzyme induction and bilirubin metabolism.
    Clinical science, 1970, Volume: 39, Issue:3

    Topics: Bilirubin; Child; Enzyme Induction; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Phen

1970
[Importance of liver glucuronyltransferase in pediatrics].
    Wiener klinische Wochenschrift, 1970, Oct-18, Volume: 82, Issue:42

    Topics: Aerosols; Age Factors; Animals; Bilirubin; Biopsy; Child; Clinical Enzyme Tests; Enzyme Induction; F

1970
[The influence of a short-time enzyme induction with phenobarbital on hyperbilirubinemia in premature newborns].
    Das Deutsche Gesundheitswesen, 1970, Nov-19, Volume: 25, Issue:47

    Topics: Bilirubin; Enzyme Induction; Glucosephosphate Dehydrogenase Deficiency; Humans; Hyperbilirubinemia;

1970
[Phenobarbital in the treatment of mainly indirect hyperbilirubinemias in adults].
    Giornale di clinica medica, 1970, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Female; Humans; Hyperbilirubinemia; Male; Phenobarbital

1970
[Influence of phenobarbital on bilirubin metabolism in Gunn rats. Experiments with inactive and 14C-labeled bilirubin].
    Zeitschrift fur Kinderheilkunde, 1970, Volume: 109, Issue:2

    Topics: Animals; Bile; Bile Pigments; Bilirubin; Carbon Isotopes; Enzyme Activation; Female; Glucuronates; H

1970
The use of phenobarbital in neonatal jaundice.
    Birth defects original article series, 1970, Volume: 6, Issue:2

    Topics: Age Factors; Animals; Bilirubin; Enzyme Induction; Female; Glucuronates; Hexosyltransferases; Humans

1970
Phototherapy of jaundice 1969.
    Birth defects original article series, 1970, Volume: 6, Issue:2

    Topics: ABO Blood-Group System; Adolescent; Age Factors; Bilirubin; Birth Weight; Blood Group Incompatibilit

1970
Drugs and the liver.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Bilirubin; Cushing Syndrome; DDT; Enzyme Induction; Ethanol; Female; Humans; Hyperbilirubinemia; Inf

1970
[New methods of treating hyperbilirubinemia in newborn infants].
    L'union medicale du Canada, 1971, Volume: 100, Issue:3

    Topics: Agar; Enzyme Induction; Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Infant, Newbo

1971
[Behavior of bilirubinemia in full-term newborn infants treated with phenobarbital].
    Minerva pediatrica, 1971, Jun-23, Volume: 23, Issue:25

    Topics: Humans; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Phenobar

1971
[Phenemal treatment of icterus intermittens juvenilis].
    Lakartidningen, 1971, May-12, Volume: 68, Issue:20

    Topics: Administration, Oral; Adult; Bilirubin; Humans; Hyperbilirubinemia; Jaundice; Male; Phenobarbital

1971
Reduction in serum bilirubin by phenobarbital in adult unconjugated hyperhilirubinaemia. Is enzyme induction responsible?
    The American journal of medicine, 1968, Volume: 45, Issue:1

    Topics: Adult; Bilirubin; Endoplasmic Reticulum; Enzyme Induction; Female; Glucuronates; Golgi Apparatus; Hu

1968
Studies on bilirubin production and excretion in mice and rats treated with phenobarbital, chlorpromazine, norethandrolone, acetohexamide or enovid.
    Toxicology and applied pharmacology, 1969, Volume: 15, Issue:2

    Topics: Acetohexamide; Animals; Bile; Bile Ducts; Bilirubin; Carbon Isotopes; Chlorpromazine; Hyperbilirubin

1969
Potentiation and inhibition of alpha-naphthylisothiocyanate-induced hyperbilirubinemia and cholestasis.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:3

    Topics: Animals; Chlorpromazine; Cholestasis; Dactinomycin; Ethionine; Hyperbilirubinemia; In Vitro Techniqu

1965