phenobarbital has been researched along with Bile Duct Obstruction in 93 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis." | 7.79 | Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013) |
| "The effect of phenobarbital treatment on bilirubin metabolism and bile secretion was studied in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis." | 7.66 | Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis. ( Malet, PF; Rosato, EF; Roy-Chowdhury, J; Shaw, L; Trotman, BW, 1983) |
| "Two brothers with progressive familial intrahepatic cholestasis were followed during four years of phenobarbital therapy to assess its long-term safety and efficacy." | 7.66 | Efficacy and safety of long-term phenobarbital therapy of familial cholestasis. ( Bloomer, JR; Ghent, CN; Hsia, YE, 1978) |
| "Serum bile acid concentrations were followed in 29 patients with cholestasis of pregnancy treated for pruritus with either phenobarbital or cholestyramine." | 7.66 | Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy. ( Laatikainen, T, 1978) |
| "Investigations in guinea pigs to evaluate interferences between cholestasis and enzymatic induction by phenobarbital, and influences that both experimental conditions exert on the levels of gamma-glutamyl transpeptidase in microsomes and other subcellular fractions, have shown that: 1) cholestasis inhibits inductions of cytochrome P-450 from phenobarbital; 2) gamma-glutamyl transpeptidase is not an inducible enzyme in guinea pig; 3) rises or ferum gamma-glutanyl transpeptidase produced either by cholestasis or phenobarbital administration, are not related to an increased enzymatic synthesis in the various subcellular fractions of liver cell." | 7.65 | [Influence of cholestasis on enzymatic induction with phenobarbital and other enzymatic aspects: experimental studies on guinea pigs]. ( Catanzano, C; Coltorti, M; Di Cesare, D; Di Simone, A; Gaeta, L; Gentile, S; Riegler, G; Rinaldi, M, 1974) |
| "Neonatal cholestasis is a common cause of jaundice among newborns." | 5.42 | Comparison of phenobarbitone and ursodeoxycholic acid in drug-augmented hepatobiliary scintigraphy for excluding the diagnosis of obstructive cholestasis in neonatal cholestasis syndrome. ( Ali, SW; Hassan, MU; Khan, SH; Malik, D; Pakala, R; Pasupula, M; Rather, TA; Yadav, N, 2015) |
| "DJS with severe cholestasis has not to our knowledge been described in the English literature." | 5.28 | Neonatal Dubin-Johnson syndrome with severe cholestasis: effective phenobarbital therapy. ( Fujisawa, T; Inokuchi, T; Kage, M; Kimura, A; Mahara, R; Ono, E; Shibao, K; Tanaka, N; Tohma, M; Ushijima, K, 1991) |
| "Phenobarbital treatment leads to a decrease of the total biliary excretion of metabolites to about 200 microgram/100 g bw/h, the metabolite pattern remaining unchanged." | 5.26 | Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis. ( Buschmann, J; Joeres, R; Richter, E; Zilly, W, 1979) |
| "Phenobarbital was administered to a patient with extrahepatic biliary obstruction who was initially thought to have cholestatic hepatitis." | 5.25 | Effect of phenobarbital in a case of extrahepatic cholestasis. ( Bismuth, H; Dhumeaux, D; Franco, D; Metreau, JM, 1975) |
| "The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis." | 3.79 | Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013) |
| "The effect of phenobarbital on urinary bile acid excretion in intrahepatic cholestasis was studied in four boys 4-43 months of age who received 10 mg/kg of body weight of phenobarbital for a period of 3 weeks-3 years." | 3.68 | Phenobarbital can aggravate a cholestatic bile acid pattern in infants with obstructive cholangiopathy. ( Nemeth, A; Strandvik, B; Wikström, SA, 1990) |
| "Treatment with phenobarbital causes an increased urinary excretion of tetrahydroxylated bile acids in patients suffering from intrahepatic cholestasis." | 3.67 | The isolation of tetrahydroxy bile acids as methyl esters from human urine and their characterization by 1H- and 13C-nuclear magnetic resonance spectroscopy. ( Back, P; Fritz, H; Populoh, C, 1984) |
| "The effect of phenobarbital treatment on bilirubin metabolism and bile secretion was studied in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis." | 3.66 | Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis. ( Malet, PF; Rosato, EF; Roy-Chowdhury, J; Shaw, L; Trotman, BW, 1983) |
| "Two brothers with progressive familial intrahepatic cholestasis were followed during four years of phenobarbital therapy to assess its long-term safety and efficacy." | 3.66 | Efficacy and safety of long-term phenobarbital therapy of familial cholestasis. ( Bloomer, JR; Ghent, CN; Hsia, YE, 1978) |
| "Serum squalene levels did not change in patients with acute hepatitis, chronic active hepatitis and liver cirrhosis, but were significantly reduced in patients with intra- and extrahepatic cholestasis." | 3.66 | Serum squalene levels in hepatobiliary diseases. ( Hirayama, C; Ikawa, S; Yamanishi, Y, 1978) |
| "Serum bile acid concentrations were followed in 29 patients with cholestasis of pregnancy treated for pruritus with either phenobarbital or cholestyramine." | 3.66 | Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy. ( Laatikainen, T, 1978) |
| " Except for the patients with cholestatic hepatitis, in whom marked cholestasis was virtually the only abnormality in liver biopsy specimens, serum bilirubin and bile acid concentrations were diminished during therapy, the hepatic clearance of sulfobromophthalein and 131-I-rose bengal was variably enhanced, and there was relief from pruritus." | 3.65 | Phenobarbital effects in cholestatic liver diseases. ( Bloomer, JR; Boyer, JL, 1975) |
| "Investigations in guinea pigs to evaluate interferences between cholestasis and enzymatic induction by phenobarbital, and influences that both experimental conditions exert on the levels of gamma-glutamyl transpeptidase in microsomes and other subcellular fractions, have shown that: 1) cholestasis inhibits inductions of cytochrome P-450 from phenobarbital; 2) gamma-glutamyl transpeptidase is not an inducible enzyme in guinea pig; 3) rises or ferum gamma-glutanyl transpeptidase produced either by cholestasis or phenobarbital administration, are not related to an increased enzymatic synthesis in the various subcellular fractions of liver cell." | 3.65 | [Influence of cholestasis on enzymatic induction with phenobarbital and other enzymatic aspects: experimental studies on guinea pigs]. ( Catanzano, C; Coltorti, M; Di Cesare, D; Di Simone, A; Gaeta, L; Gentile, S; Riegler, G; Rinaldi, M, 1974) |
| "Cholestasis produced by ethinyl estradiol administration or biliary obstruction reduced Y, Z, BSP K(1) and hepatic BSP content." | 3.65 | Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis. ( Arias, IM; Gatmaitan, Z; Levi, AJ; Reyes, H, 1971) |
| "Cholestasis was observed to disappear in 38 (group I) patients and to persist in 42 (group II) patients, as judged from their total blood bilirubin levels, the conjugated/total bilirubin ratio, measurements of cholesterol, bile acids and alkaline phosphatase, and of Rose Bengal fecal excretion." | 2.66 | Effects of postoperative cholestyramine and phenobarbital administration on bile flow restoration in infants with extrahepatic biliary atresia. ( Couturier, M; Lemonnier, F; Odièvre, M; Vajro, P, 1986) |
| "Neonatal cholestasis is a common cause of jaundice among newborns." | 1.42 | Comparison of phenobarbitone and ursodeoxycholic acid in drug-augmented hepatobiliary scintigraphy for excluding the diagnosis of obstructive cholestasis in neonatal cholestasis syndrome. ( Ali, SW; Hassan, MU; Khan, SH; Malik, D; Pakala, R; Pasupula, M; Rather, TA; Yadav, N, 2015) |
| "The treatment with ondansetron may also have effects on the pruritus of patients with cholestasis." | 1.32 | [Pathogenesis and treatment of pruritus in patients with cholestasis]. ( Blumenstein, I; Schirrmacher, S; Stein, J, 2003) |
| "Pruritus was a prominent symptom in five." | 1.30 | Nonsyndromic paucity of interlobular bile ducts: clinical and laboratory findings of 10 cases. ( Cağlar, M; Göğüş, S; Gürakan, F; Kale, G; Koçak, N; Yüce, A, 1997) |
| "DJS with severe cholestasis has not to our knowledge been described in the English literature." | 1.28 | Neonatal Dubin-Johnson syndrome with severe cholestasis: effective phenobarbital therapy. ( Fujisawa, T; Inokuchi, T; Kage, M; Kimura, A; Mahara, R; Ono, E; Shibao, K; Tanaka, N; Tohma, M; Ushijima, K, 1991) |
| "Its routine use in the evaluation of neonatal jaundice is therefore highly recommended." | 1.26 | Effect of phenobarbital on 99mTc-IDA scintigraphy in the evaluation of neonatal jaundice. ( Altman, RP; Majd, M; Reba, RC, 1981) |
| "Phenobarbital treatment leads to a decrease of the total biliary excretion of metabolites to about 200 microgram/100 g bw/h, the metabolite pattern remaining unchanged." | 1.26 | Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis. ( Buschmann, J; Joeres, R; Richter, E; Zilly, W, 1979) |
| "The experimental cholestasis is accompanied by accumulation of hydroxylated derivatives of cholesterol, which possess the detergent characteristics and destruct the substrate binding sites in P-450 molecule." | 1.26 | [Induction of liver microsomal monoxygenases in experimental cholestasis]. ( Liakhovich, VV; Mordvinov, VA; Tsyrlov, IB; Zakharova, NE, 1976) |
| "Phenobarbital alone has been useful, so far, in the treatment of cholesterol gallstones." | 1.25 | Barbituates and biliary function. ( Capron, JP; Erlinger, S, 1975) |
| "Phenobarbital was administered to a patient with extrahepatic biliary obstruction who was initially thought to have cholestatic hepatitis." | 1.25 | Effect of phenobarbital in a case of extrahepatic cholestasis. ( Bismuth, H; Dhumeaux, D; Franco, D; Metreau, JM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (84.95) | 18.7374 |
| 1990's | 7 (7.53) | 18.2507 |
| 2000's | 2 (2.15) | 29.6817 |
| 2010's | 5 (5.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwatra, N | 1 |
| Shalaby-Rana, E | 1 |
| Narayanan, S | 1 |
| Mohan, P | 1 |
| Ghelani, S | 1 |
| Majd, M | 2 |
| Basu, S | 1 |
| Bhattacharya, A | 1 |
| Malik, D | 2 |
| Khan, SH | 1 |
| Ali, SW | 1 |
| Rather, TA | 1 |
| Pakala, R | 1 |
| Hassan, MU | 1 |
| Yadav, N | 1 |
| Pasupula, M | 1 |
| Sadeghi, R | 1 |
| Schirrmacher, S | 1 |
| Blumenstein, I | 1 |
| Stein, J | 1 |
| Smits-Wintjens, VE | 1 |
| Walther, FJ | 1 |
| Lopriore, E | 1 |
| Back, P | 2 |
| Fritz, H | 1 |
| Populoh, C | 1 |
| Fears, R | 1 |
| Rush, WR | 1 |
| Walker, P | 1 |
| Ferres, H | 1 |
| Trotman, BW | 1 |
| Shaw, L | 1 |
| Roy-Chowdhury, J | 1 |
| Malet, PF | 1 |
| Rosato, EF | 1 |
| Bloomer, JR | 3 |
| Ghent, CN | 2 |
| Shaw, D | 1 |
| Frohlich, J | 1 |
| Wittmann, BA | 1 |
| Willms, M | 1 |
| Reba, RC | 1 |
| Altman, RP | 1 |
| Dockter, G | 1 |
| Müller, J | 1 |
| Koçak, N | 1 |
| Gürakan, F | 1 |
| Yüce, A | 1 |
| Cağlar, M | 1 |
| Kale, G | 1 |
| Göğüş, S | 1 |
| Aagenaes, O | 1 |
| Stutts, JT | 1 |
| Washington, K | 1 |
| Barnard, JA | 1 |
| Margaria, E | 1 |
| Palieri Furlan, L | 1 |
| Marioni, A | 1 |
| Magro, M | 1 |
| Lovera, C | 1 |
| Capron, JP | 1 |
| Erlinger, S | 3 |
| Mackinnon, M | 1 |
| Simon, F | 1 |
| Stiehl, A | 5 |
| Sann, L | 1 |
| Gonciarz, Z | 1 |
| Czarnecka, K | 1 |
| Wehinger, H | 1 |
| Blasco, PA | 1 |
| Tsyrlov, IB | 2 |
| Polyakova, NE | 1 |
| Gromova, OA | 1 |
| Rivkind, NB | 1 |
| Lyakhovich, VV | 1 |
| Richter, E | 3 |
| Joeres, R | 1 |
| Buschmann, J | 1 |
| Zilly, W | 2 |
| Frysák, Z | 1 |
| Hauftová, D | 1 |
| Jezdinská, V | 1 |
| Dusek, J | 1 |
| Leiber, DU | 1 |
| Lagenstein, I | 1 |
| Grüttner, R | 1 |
| Hsia, YE | 2 |
| Levy, VG | 4 |
| Nusinovici, V | 4 |
| Noel, P | 1 |
| Yamanishi, Y | 1 |
| Ikawa, S | 1 |
| Hirayama, C | 2 |
| Drew, R | 1 |
| Priestly, BG | 1 |
| Laatikainen, T | 1 |
| Darnis, F | 1 |
| Caroli, J | 3 |
| Schmeisser, W | 1 |
| Eggstein, M | 1 |
| Maulbetsch, R | 1 |
| Dölle, W | 1 |
| Marmo, E | 1 |
| Di Mezza, F | 1 |
| Brita, G | 1 |
| Grella, A | 1 |
| Alfano, C | 1 |
| Javitt, NB | 2 |
| Metreau, JM | 1 |
| Bismuth, H | 1 |
| Franco, D | 1 |
| Dhumeaux, D | 2 |
| Boyer, JL | 1 |
| Lázló, B | 1 |
| Méhesfalvi, E | 1 |
| Sturdevant, RA | 1 |
| Klapdor, R | 1 |
| Schliewe, J | 1 |
| Valerius, H | 1 |
| Zakharova, NE | 1 |
| Mordvinov, VA | 1 |
| Liakhovich, VV | 1 |
| Williams, CN | 1 |
| Dahlström-King, L | 1 |
| Couture, J | 1 |
| Plaa, GL | 2 |
| Kimura, A | 1 |
| Ushijima, K | 1 |
| Kage, M | 1 |
| Mahara, R | 1 |
| Tohma, M | 1 |
| Inokuchi, T | 1 |
| Shibao, K | 1 |
| Tanaka, N | 1 |
| Fujisawa, T | 1 |
| Ono, E | 1 |
| Stolzenbach, JC | 1 |
| Larson, RE | 1 |
| Nemeth, A | 1 |
| Wikström, SA | 1 |
| Strandvik, B | 1 |
| Bachs, L | 1 |
| Parés, A | 1 |
| Elena, M | 1 |
| Piera, C | 1 |
| Rodés, J | 1 |
| Nagatomo, Y | 1 |
| Ahmed, AE | 1 |
| Grissom, M | 1 |
| el-Azhary, R | 1 |
| Haque, A | 1 |
| Boor, PJ | 1 |
| Costanzi, J | 1 |
| Vajro, P | 1 |
| Couturier, M | 1 |
| Lemonnier, F | 1 |
| Odièvre, M | 1 |
| Le Thai, B | 1 |
| Dumont, M | 1 |
| Michel, A | 1 |
| Houssin, D | 1 |
| Palomeque, A | 1 |
| Doménech, P | 1 |
| Martínez-Gutiérrez, A | 1 |
| Lequerica, P | 1 |
| Stillman, AE | 1 |
| Earnest, DL | 1 |
| Woolfenden, JM | 1 |
| Alagille, D | 1 |
| Di Simone, A | 1 |
| Catanzano, C | 1 |
| Riegler, G | 1 |
| Rinaldi, M | 1 |
| Di Cesare, D | 1 |
| Gentile, S | 1 |
| Gaeta, L | 1 |
| Coltorti, M | 1 |
| Thompson, RP | 2 |
| Williams, R | 2 |
| Cunningham, MD | 1 |
| Kelley, LR | 1 |
| Peters, ER | 1 |
| Thaler, MM | 4 |
| Dallman, PR | 1 |
| Goodman, J | 1 |
| Buffoni, L | 1 |
| De Santis, L | 1 |
| Sanbe, K | 1 |
| Kamegaya, K | 1 |
| Oda, M | 1 |
| Okazaki, I | 1 |
| Braun, W | 1 |
| Wöckel, W | 1 |
| Giertler, U | 1 |
| Vollmar, F | 1 |
| Grün, M | 1 |
| Brachtel, D | 1 |
| Kühn, HA | 2 |
| Stacher, G | 1 |
| Admirand, WH | 2 |
| Ballow, M | 1 |
| Margolis, CZ | 1 |
| Schachtel, B | 1 |
| Linarelli, LG | 1 |
| Hengstenberg, FH | 1 |
| Drash, AL | 1 |
| Gumucio, JJ | 1 |
| Accatino, L | 1 |
| Macho, AM | 1 |
| Contreras, A | 1 |
| Blinder, LV | 1 |
| Gasparian, SA | 1 |
| Maliugin, EF | 1 |
| Kliuchnikova, ZhI | 1 |
| Archakov, AI | 1 |
| Leinweber, W | 1 |
| Mühlenkamp, H | 1 |
| Erb, W | 1 |
| Amar, AB | 1 |
| Espinoza, J | 1 |
| Barnafi, L | 1 |
| Schnaidt, E | 1 |
| Mackinnon, AM | 1 |
| Simon, FR | 1 |
| Harris, RC | 1 |
| Sharp, HL | 1 |
| Mirkin, BL | 1 |
| Reyes, H | 1 |
| Levi, AJ | 1 |
| Gatmaitan, Z | 1 |
| Arias, IM | 1 |
| Horký, J | 1 |
| Grasso, P | 1 |
| Golberg, L | 1 |
| Okolicsanyi, L | 1 |
| Frei, J | 1 |
| Magnenat, P | 1 |
| Read, AE | 1 |
| Roberts, RJ | 1 |
15 reviews available for phenobarbital and Bile Duct Obstruction
| Article | Year |
|---|---|
Rhesus haemolytic disease of the newborn: Postnatal management, associated morbidity and long-term outcome.
Topics: Albumins; Anemia, Neonatal; Cholestasis; Fluid Therapy; Humans; Hydrops Fetalis; Hyperbilirubinemia, | 2008 |
[Atypical bile acids (author's transl)].
Topics: Bile Acids and Salts; Bile Ducts; Biological Evolution; Cell Membrane; Cholestanol; Cholestanols; Ch | 1980 |
Management of the intractable cholestasis of primary biliary cirrhosis.
Topics: Bile Acids and Salts; Calcium; Cholestasis; Cholestyramine Resin; Copper; Food, Formulated; Humans; | 1981 |
Hereditary cholestasis with lymphoedema (Aagenaes syndrome, cholestasis-lymphoedema syndrome). New cases and follow-up from infancy to adult age.
Topics: Adolescent; Adult; Child; Child, Preschool; Cholestasis; Consanguinity; Female; Follow-Up Studies; G | 1998 |
Disturbances of bile acid metabolism in cholestasis.
Topics: Bile Acids and Salts; Bile Ducts; Cholestasis; Cholestyramine Resin; Deoxycholic Acid; Disease Model | 1977 |
[Metabolism of bile acids. General review and peculiarities in pediatrics].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bile Acids and Salts; Chemical Phenomena; Chemistry; Child | 1977 |
[Phenobarbital in the treatment of hepatic disorders of bilirubin metabolism].
Topics: Bilirubin; Cholestasis; Drug Evaluation; Humans; Hyperbilirubinemia; Jaundice, Chronic Idiopathic; L | 1979 |
[Congenital nonhemolytic hyperbilirubinemias].
Topics: Adolescent; Adult; Age Factors; Bilirubin; Child; Child, Preschool; Cholestasis; Chronic Disease; Cr | 1977 |
[Hepatic-cell enzyme induction using phenobarbital: applications to the treatment of jaundice].
Topics: Bile Acids and Salts; Bilirubin; Cholestasis; Chronic Disease; Enzyme Induction; Gilbert Disease; Hu | 1976 |
Mechanisms and control of secretion of bile water and electrolytes.
Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Biological Transport, Active; Blood Flow Velocity; | 1974 |
[Advances in the treatment of jaundice in the department of internal medicine].
Topics: Adrenal Cortex Hormones; Adult; Bilirubin; Cholestasis; Female; Humans; Hyperbilirubinemia; Jaundice | 1972 |
[Pathophysiology and clinical aspects of intrahepatic cholestasis].
Topics: Alkaline Phosphatase; Animals; Arsphenamine; Bile Acids and Salts; Bilirubin; Chlorpromazine; Cholan | 1970 |
The cholestatic syndrome--1971.
Topics: Alkaline Phosphatase; Bile; Bile Acids and Salts; Bile Ducts, Intrahepatic; Cell Membrane Permeabili | 1971 |
[Enzyme induction therapy of liver diseases].
Topics: Adrenal Cortex Hormones; Anabolic Agents; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Gluc | 1971 |
The newer hyperbilirubinemias.
Topics: ABO Blood-Group System; Anemia, Hemolytic; Antigen-Antibody Reactions; Bilirubin; Biological Transpo | 1968 |
3 trials available for phenobarbital and Bile Duct Obstruction
| Article | Year |
|---|---|
Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis.
Topics: Adult; Cholestasis; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Liver Ci | 1989 |
Effects of postoperative cholestyramine and phenobarbital administration on bile flow restoration in infants with extrahepatic biliary atresia.
Topics: Barbiturates; Bile Ducts; Cholestasis; Cholestyramine Resin; Clinical Trials as Topic; Humans; Infan | 1986 |
Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood.
Topics: Bile; Bile Acids and Salts; Bilirubin; Biopsy; Child; Child, Preschool; Cholestasis; Chronic Disease | 1972 |
75 other studies available for phenobarbital and Bile Duct Obstruction
| Article | Year |
|---|---|
Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center.
Topics: Biliary Atresia; Causality; Cholestasis; District of Columbia; Female; Humans; Image Enhancement; In | 2013 |
Ursodeoxycholic acid versus phenobarbital pretreatment prior to hepatobiliary scintigraphy in neonatal cholestasis: is it time for shifting gears towards a practice change?
Topics: Biliary Tract; Cholagogues and Choleretics; Cholestasis; Humans; Hypnotics and Sedatives; Infant; Li | 2015 |
Comparison of phenobarbitone and ursodeoxycholic acid in drug-augmented hepatobiliary scintigraphy for excluding the diagnosis of obstructive cholestasis in neonatal cholestasis syndrome.
Topics: Biliary Tract; Cholestasis; Female; Humans; Infant; Infant, Newborn; Liver; Male; Phenobarbital; Rad | 2015 |
Drug augmented hepatobiliary scintigraphy for evaluation of neonatal cholestasis: what does the evidence point to?
Topics: Biliary Tract; Cholestasis; Female; Humans; Liver; Male; Phenobarbital; Radionuclide Imaging; Ursode | 2015 |
Drug-augmented hepatobiliary scintigraphy for evaluation of neonatal cholestasis: What does the evidence point to?
Topics: Biliary Tract; Cholestasis; Female; Humans; Liver; Male; Phenobarbital; Radionuclide Imaging; Ursode | 2015 |
[Pathogenesis and treatment of pruritus in patients with cholestasis].
Topics: Brain; Cholestasis; Cholestyramine Resin; Dronabinol; Enzyme Induction; Humans; Liver; Narcotic Anta | 2003 |
The isolation of tetrahydroxy bile acids as methyl esters from human urine and their characterization by 1H- and 13C-nuclear magnetic resonance spectroscopy.
Topics: Bile Acids and Salts; Carbon Isotopes; Chemical Phenomena; Chemistry; Cholestasis; Chromatography, G | 1984 |
Hyperalphalipoproteinaemic activity of BRL 26314--I. Enhanced cholesterol turnover in rats.
Topics: 1-Naphthylisothiocyanate; Animals; Bile Acids and Salts; Biological Transport; Cholestasis; Choleste | 1984 |
Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis.
Topics: Adult; Bile; Cholestasis; Crigler-Najjar Syndrome; Humans; Hyperbilirubinemia, Hereditary; Liver Fun | 1983 |
A prospective study of 18 patients with cholestasis of pregnancy.
Topics: Adolescent; Adult; Amniotic Fluid; Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Drug The | 1982 |
Effect of phenobarbital on 99mTc-IDA scintigraphy in the evaluation of neonatal jaundice.
Topics: Bile Ducts; Cholestasis; Common Bile Duct; Diagnosis, Differential; Evaluation Studies as Topic; Fem | 1981 |
[Familial recurring intrahepatic cholestasis of the Tygstrup-Summerskill-Walshe type].
Topics: Adult; Child, Preschool; Cholestasis; Cholestyramine Resin; Female; Humans; Liver; Male; Phenobarbit | 1980 |
Nonsyndromic paucity of interlobular bile ducts: clinical and laboratory findings of 10 cases.
Topics: Bile Ducts; Biopsy; Child, Preschool; Cholestasis; Cholestyramine Resin; Consanguinity; Female; Huma | 1997 |
Cholestatic jaundice with skin desquamation in a 12-year-old girl.
Topics: Atropine; Child; Cholestasis; Cryptogenic Organizing Pneumonia; Drug Combinations; Fatal Outcome; Fe | 1999 |
[Endogenous intoxications of pregnancy: jaundice of pregnancy].
Topics: Adult; Arginine; Bicarbonates; Cholestasis; Cholestyramine Resin; Dextrans; Fatty Liver; Female; Glu | 1979 |
Barbituates and biliary function.
Topics: Adenosine Triphosphatases; Animals; Bile; Bile Acids and Salts; Biliary Tract; Bilirubin; Cholelithi | 1975 |
Pharmacological reversal of cholestasis-associated decrease in hepatic cytochrome P-450.
Topics: Animals; Bile Ducts; Cholestasis; Cytochrome P-450 Enzyme System; Depression, Chemical; Ethinyl Estr | 1975 |
Phenobarbital therapy for cholestasis.
Topics: Child; Cholestasis; Chronic Disease; Humans; Phenobarbital | 1979 |
Cholestasis as an in vivo model for analysis of the induction of liver microsomal monooxygenases by sodium phenobarbital and 3-methylcholanthrene.
Topics: Animals; Cholestasis; Deoxycholic Acid; Enzyme Induction; In Vitro Techniques; Kinetics; Lipid Metab | 1979 |
Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Cholestasis; Chromatography, Thin Layer; Galactosamine; Hep | 1979 |
[Intrahepatic cholestasis following ketazone successfully treated using the enzyme inductor phenobarbital].
Topics: Cholestasis; Female; Humans; Oxyphenbutazone; Phenobarbital; Vaginitis | 1978 |
[Benign recurrent cholestasis in monozygotic twin girls (author's transl)].
Topics: Child; Child, Preschool; Cholestasis; Cholestyramine Resin; Diseases in Twins; Female; Humans; Pheno | 1979 |
Efficacy and safety of long-term phenobarbital therapy of familial cholestasis.
Topics: Bile Acids and Salts; Calcium; Child, Preschool; Cholestasis; Humans; Liver Function Tests; Male; Ph | 1978 |
[Enzyme induction and intrahepatic cholestasis].
Topics: Bilirubin; Cholestasis; Clofibrate; Coenzyme A Ligases; Enzyme Induction; Glucuronates; Glutethimide | 1978 |
Serum squalene levels in hepatobiliary diseases.
Topics: Acute Disease; Adult; Azathioprine; Biliary Tract Diseases; Cholestasis; Cholesterol; Cholestyramine | 1978 |
Failure of hypoactive hypertrophic smooth endoplasmic reticulum to produce cholestasis in rats.
Topics: Animals; Cholestasis; Cobalt; Endoplasmic Reticulum; Hypertrophy; Lithocholic Acid; Liver Function T | 1978 |
Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy.
Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholestyramine Resin; Cholic Acids; | 1978 |
[Treatment of various forms of icterus or cholestasis with phenobarbital (author's transl)].
Topics: Adult; Anemia, Hemolytic; Cholangitis; Cholestasis; Crigler-Najjar Syndrome; Gilbert Disease; Humans | 1977 |
[A case of benign recurring intrahepatic cholestasis (Tygstrup-Summerskill and Walshe syndrome)].
Topics: Adult; Alkaline Phosphatase; Biopsy; Cholestasis; Cholestyramine Resin; Diet Therapy; Humans; Hyperb | 1977 |
Drug induction and experimental cholestasis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis; Cytochrome P-450 | 1976 |
Cholestasis in infancy. Status report and conceptual approach.
Topics: alpha 1-Antitrypsin Deficiency; Anion Exchange Resins; Bacterial Infections; Bile; Bile Ducts; Bile | 1976 |
Effect of phenobarbital in a case of extrahepatic cholestasis.
Topics: Adult; Bile Acids and Salts; Bilirubin; Cholestasis; Diagnosis, Differential; Female; Humans; Phenob | 1975 |
Phenobarbital effects in cholestatic liver diseases.
Topics: Adult; Bile Ducts, Intrahepatic; Bilirubin; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangi | 1975 |
[Phenobarbital and cholestyramin in recurrent intrahepatic cholestasis].
Topics: Adolescent; Adult; Cholestasis; Cholestyramine Resin; Glucocorticoids; Humans; Immunosuppressive Age | 1975 |
Medical treatment of gallstones.
Topics: Animals; Arteriosclerosis; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Di | 1975 |
[Mechanisms of bile secretion in mini-pigs (author's transl)].
Topics: Animals; Bile; Bile Acids and Salts; Cholecystectomy; Cholecystokinin; Cholelithiasis; Cholestasis; | 1975 |
[Letter: Treatment of cholestatic hepatitis by enzyme inductors].
Topics: Cholestasis; Enzyme Induction; Glutethimide; Hepatitis; Humans; Phenobarbital | 1976 |
[Induction of liver microsomal monoxygenases in experimental cholestasis].
Topics: Animals; Cholestasis; Enzyme Induction; Male; Microsomes, Liver; Oxygenases; Phenobarbital; Rats | 1976 |
Bile-acid metabolism and the liver.
Topics: Barbiturates; Bile Acids and Salts; Cholestasis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Phe | 1976 |
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis.
Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cy | 1992 |
Neonatal Dubin-Johnson syndrome with severe cholestasis: effective phenobarbital therapy.
Topics: Bile Acids and Salts; Bilirubin; Cholestasis; Humans; Infant, Newborn; Jaundice, Chronic Idiopathic; | 1991 |
BCNU-induced quantitative and qualitative changes in hepatic cytochrome P-450 can be correlated with cholestasis.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carmustine; Cholestasis; Cytochrome P-450 Enzyme System | 1990 |
Phenobarbital can aggravate a cholestatic bile acid pattern in infants with obstructive cholangiopathy.
Topics: Bile Acids and Salts; Child, Preschool; Cholangiography; Cholestasis; Humans; Infant; Liver Function | 1990 |
[Studies on the mechanism of gamma-glutamyltranspeptidase elevation in serum--concerning its hydrophobic and hydrophilic forms].
Topics: Animals; Bile; Cholestasis; Ethanol; gamma-Glutamyltransferase; Guinea Pigs; Humans; Liver; Liver Di | 1987 |
Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Chemical and Drug Induced Liver In | 1987 |
Cyclosporine-induced cholestasis: inhibition of bile acid secretion is caused by the parental molecule.
Topics: Animals; Bile Acids and Salts; Biotransformation; Cholestasis; Cyclosporins; Male; Phenobarbital; Ra | 1987 |
[Severe hypersensitivity to phenobarbital with erythema multiforme, cholestatic hepatitis and aplastic anemia].
Topics: Anemia, Aplastic; Chemical and Drug Induced Liver Injury; Child; Cholestasis; Drug Hypersensitivity; | 1986 |
Hepatobiliary scintigraphy for cholestasis in congenital hepatic fibrosis. Diagnosis and treatment.
Topics: Bile Ducts, Intrahepatic; Child; Cholangitis; Cholestasis; Dehydrocholic Acid; Gentamicins; Humans; | 1985 |
Management of paucity of interlobular bile ducts.
Topics: Bile Ducts, Intrahepatic; Cholestasis; Cholestyramine Resin; Dietary Fats; Humans; Infant, Newborn; | 1985 |
[Influence of cholestasis on enzymatic induction with phenobarbital and other enzymatic aspects: experimental studies on guinea pigs].
Topics: Animals; Cholestasis; Common Bile Duct; Cytochrome P-450 Enzyme System; Enzyme Induction; gamma-Glut | 1974 |
Treatment of chronic intrahepatic cholestasis with phenobarbitone.
Topics: Aged; Bilirubin; Cholestasis; Enzyme Induction; Female; Humans; Hyperbilirubinemia; Liver Function T | 1967 |
Phenobarbitone in cholestasis.
Topics: Biliary Tract; Cholestasis; Humans; Infant; Male; Phenobarbital | 1968 |
Phenobarbitone in intrahepatic biliary atresia.
Topics: Adult; Bile Ducts, Intrahepatic; Biliary Tract Diseases; Cholestasis; Humans; Infant; Infant, Newbor | 1970 |
Phenobarbital-induced changes in NADPH-cytochrome c reductase and smooth endoplasmic reticulum in human liver.
Topics: Biopsy; Biotransformation; Child, Preschool; Cholestasis; Electron Transport Complex IV; Endoplasmic | 1972 |
Effect of phenobarbital on hepatic transport and excretion of 131 I-rose bengal in children with cholestasis.
Topics: Autoradiography; Bile; Biliary Tract Diseases; Bilirubin; Cholestasis; Feces; Female; Humans; Infant | 1972 |
[Cholestatic jaundice and phenobarbital].
Topics: Bile Ducts; Child, Preschool; Cholestasis; Female; Humans; Phenobarbital | 1974 |
[Phenobarbital treatment of benign recurrent intrahepatic cholestasis].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Biopsy; Cholestasis; Female; Humans; I | 1972 |
[Treatment of cholestasis with phenobarbital].
Topics: Bile Ducts, Intrahepatic; Cholestasis; Humans; Liver Cirrhosis; Liver Diseases; Phenobarbital | 1972 |
[Drug metabolism in experimental cholestasis].
Topics: Animals; Cholestasis; Hexobarbital; Phenobarbital; Rats | 1972 |
Intrahepatic cholostasis following combined diazepam-barbiturate therapy in patients with tetanus.
Topics: Adult; Aged; Anti-Bacterial Agents; Chlorpromazine; Cholestasis; Diazepam; Drug Combinations; Female | 1973 |
Effects of phenobarbital on bile salt metabolism in cholestasis due to intrahepatic bile duct hypoplasia.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; B | 1973 |
Progressive familial intrahepatic cholestasis.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; C | 1973 |
Effect of phenobarbital on hyperlipemia in patients with intrahepatic and extrahepatic cholestasis.
Topics: Alkaline Phosphatase; Bilirubin; Blood Protein Electrophoresis; Child; Child, Preschool; Cholestasis | 1973 |
Effect of phenobarbital on the ethynyl estradiol-induced cholestasis in the rat.
Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Cycloheximide; Dactinomycin; Ethinyl Estradiol; Fe | 1973 |
[Use of enzyme tests for diagnosing the character of toxic liver damage and for controlling the effectiveness of chemotherapy for CCl-4 poisoning].
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug I | 1973 |
[Influence of phenobarbital therapy on serum and liver total and single bile acids of healthy rats and rats with ANIT cholestasis].
Topics: Animals; Bile Acids and Salts; Cholestasis; Liver; Phenobarbital; Rats; Thiocyanates | 1973 |
[Acholangic cholestatic hepatitis evolving towards xanthomatosis and cirrhosis].
Topics: Bile Ducts; Bilirubin; Biopsy; Blood Proteins; Cholestasis; Female; Glutethimide; Hepatitis; Humans; | 1973 |
The effect of phenobarbital on intrahepatic cholestasis of pregnancy.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Pro | 1974 |
Reduced synthesis of hepatic microsomal cytochroma P450 in the bile duct ligated rat.
Topics: Animals; Apoproteins; Carbon Radioisotopes; Cholestasis; Common Bile Duct; Cytochrome P-450 Enzyme S | 1974 |
The effects of phenobarbital on bile salts and bilirubin in patients with intrahepatic and extrahepatic cholestasis.
Topics: Bile Acids and Salts; Bile Ducts, Intrahepatic; Bilirubin; Child, Preschool; Cholestasis; Female; Hu | 1972 |
Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis.
Topics: Allyl Compounds; Animals; Benzopyrenes; Cholestasis; DDT; Densitometry; Dieldrin; Dwarfism, Pituitar | 1971 |
Influence of phenobarbital on histological and biochemical changes in experimental intrahepatic cholestasis.
Topics: Alkaline Phosphatase; Animals; Bilirubin; Cholestasis; Cholesterol; Female; Hyperbilirubinemia; Live | 1971 |
Multiplicity and specificity of UDP-glucuronyl transferase. II. Influence of phenobarbital and cholestasis on the activity of glucuronyl transferase and beta-glucuronidase in rat liver.
Topics: Animals; Bilirubin; Cholestasis; Coumarins; Female; Glucuronates; Glucuronidase; Liver; Male; Nitrop | 1970 |
Drugs and liver disease.
Topics: Biliary Tract Diseases; Bilirubin; Brain Diseases; Carbon Tetrachloride Poisoning; Chemical and Drug | 1969 |
Potentiation and inhibition of alpha-naphthylisothiocyanate-induced hyperbilirubinemia and cholestasis.
Topics: Animals; Chlorpromazine; Cholestasis; Dactinomycin; Ethionine; Hyperbilirubinemia; In Vitro Techniqu | 1965 |