Page last updated: 2024-11-02

phenobarbital and Benign Psychomotor Epilepsy, Childhood

phenobarbital has been researched along with Benign Psychomotor Epilepsy, Childhood in 143 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial."9.04Treatment of epilepsy with clonazepam and its effect on other anticonvulsants. ( Johnson, RH; Keogh, HJ; Lambie, DG; Melville, ID; Nanda, RN, 1977)
" In the present study, we used a post-status epilepticus model of TLE to examine whether rats with spontaneous recurrent seizures (SRSs) differ in their individual responses to phenobarbital (PB)."7.72Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus. ( Brandt, C; Löscher, W; Volk, HA, 2004)
"An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation."7.66Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979)
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."7.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
"All the seizure parameters were significantly reduced when phenobarbital (3 mg/kg) was administered prior to the application of the non-effective pattern of LFS."5.40Combined sub-threshold dosages of phenobarbital and low-frequency stimulation effectively reduce seizures in amygdala-kindled rats. ( Asgari, A; Atapour, N; Mirnajafi-Zadeh, J; Moradi, H; Semnanian, S; Shojaei, A, 2014)
"QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)."5.27Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986)
" Fluctuations in the blood phenobarbital content from one administration to another is important for selecting its optimal dosage and the interval between intakes."5.27[Concentration of phenobarbital in biological fluids during the treatment of epilepsy patients]. ( Antadze, ZI; Okudzhava, VM; Vetrogon, FG, 1984)
"Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial."5.04Treatment of epilepsy with clonazepam and its effect on other anticonvulsants. ( Johnson, RH; Keogh, HJ; Lambie, DG; Melville, ID; Nanda, RN, 1977)
"A group of 27 patients with various types of epilepsy were selected for a 6-month double-blind crossover study to compare the anticonvulsant effect and toxicity of eterobarb and phenobarbital."5.04Eterobarb therapy in epilepsy. ( Hanahan, E; Mattson, RH; Williamson, PD, 1976)
" In pentylenetetrazole-induced acute seizures only BUM532 combined with a sub-effective dose of PB increased the seizure threshold."3.96Functional characterization of novel bumetanide derivatives for epilepsy treatment. ( Auer, T; Erker, T; Schreppel, P; Schwarzer, C, 2020)
"We made a microPET evaluation of the effects of tariquidar on the brain kinetics of the P-glycoprotein substrate [(18) F]MPPF in a rat model with spontaneous recurrent seizures, in which it has previously been demonstrated that phenobarbital nonresponders exhibit higher P-glycoprotein expression than do phenobarbital responders."3.76Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: proof-of-concept in a chronic rat model of temporal lobe epilepsy. ( Bartenstein, P; Bartmann, H; Böning, G; Cumming, P; Fuest, C; Just, T; la Fougere, C; Pekcec, A; Potschka, H; Schlichtiger, J; Soerensen, J; Wängler, B; Winter, P; Xiong, G, 2010)
"In the present study we examined if rats with PB-resistant seizures are also resistant to phenytoin (PHT), using continuous EEG/video recording of spontaneous seizures."3.74Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy. ( Bethmann, K; Brandt, C; Löscher, W, 2007)
" In the present study, we used a post-status epilepticus model of TLE to examine whether rats with spontaneous recurrent seizures (SRSs) differ in their individual responses to phenobarbital (PB)."3.72Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus. ( Brandt, C; Löscher, W; Volk, HA, 2004)
" The second patient complained of impotence after a rash while taking phenytoin and carbamazepine."3.70Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000)
" Five years later she developed myasthenia gravis, and phenytoin was replaced by valproic acid and phenobarbital."3.68Epilepsy, myasthenia gravis, and effect of plasmapheresis on antiepileptic drug concentrations. ( Jenkins, DC; Lai, CW; Leppik, IE; Sood, P, 1990)
"An epileptic patient whose seizures were controlled with carbamazepine and primidone was followed throughout pregnancy and lactation."3.66Carbamazepine levels in pregnancy and lactation. ( Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR, 1979)
"Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)."3.65Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975)
" The data indicate that the dosage regimen described is suitable for patients on oral phenytoin who have to be transferred to im drug for short periods."2.64Oral and intramuscular phenytoin. ( Ramsay, RE; Wilder, BJ, 1976)
"Carbamazepine was found to be an effective anticonvulsant in the treatment of grand mal epilepsy."2.64Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy. ( Christiansen, J; Dam, M; Jensen, A, 1975)
"This study was undertaken to determine the relationship of serum ACD levels to dosage in a group of patients who had been seizure free for at least two years."2.64The relation of anticonvulsant drug levels to complete seizure control. ( Feldman, RG; Pippenger, CE, 1976)
"Drug treatment of status epilepticus is reviewed."2.36Drug therapy reviews: drug therapy of status epilepticus. ( Browne, TR, 1978)
"Spontaneous recurrent seizures (SRS) in TLE can present after a latent period following a neurological insult (traumatic brain injury, SE event, viral infection, etc."1.62Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital. ( Barker-Haliski, M; Knox, K; Koneval, Z; Metcalf, C; White, HS; Wilcox, KS; Zierath, D, 2021)
"In a first step, we examined anti-seizure effects of 6 AEDs on spontaneous recurrent focal electrographic seizures and secondarily generalized convulsive seizures in epileptic mice, showing that the focal nonconvulsive seizures were resistant to carbamazepine and phenytoin, whereas valproate and levetiracetam exerted moderate and phenobarbital and diazepam marked anti-seizure effects."1.42Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice. ( Bankstahl, M; Klein, S; Löscher, W, 2015)
"All the seizure parameters were significantly reduced when phenobarbital (3 mg/kg) was administered prior to the application of the non-effective pattern of LFS."1.40Combined sub-threshold dosages of phenobarbital and low-frequency stimulation effectively reduce seizures in amygdala-kindled rats. ( Asgari, A; Atapour, N; Mirnajafi-Zadeh, J; Moradi, H; Semnanian, S; Shojaei, A, 2014)
"Epilepsy with spontaneous recurrent seizures (SRS) was induced by status epilepticus."1.36High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy. ( Brandt, C; Löscher, W, 2010)
" Based on pharmacokinetic studies with bumetanide, which showed extremely rapid elimination and low brain penetration of this drug in rats, bumetanide was administered systemically with different dosing protocols, including continuous intravenous infusion."1.36Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy. ( Brandt, C; Heuchert, N; Löscher, W; Nozadze, M; Rattka, M, 2010)
" Creatinine concentrations should not be considered when dosage adjustments of renally eliminated drugs are being calculated for patients with such metabolic interferences."1.29Creatinine metabolism impairment by an anticonvulsant drug, phenacemide. ( Baltassat, P; Cahen, R; Francois, B; Louisot, P; Martin, A, 1994)
"Benign Familial Neonatal Seizures (BFNS) occur in normal newborns without perinatal neurological damage or metabolic abnormalities in the setting of a positive family history for neonatal seizures."1.28Benign Familial Neonatal Seizures. ( Dworsky, ME; Raispis, T, 1992)
"These findings represent VPA-induced sensorineural hearing loss, possibly in preexisting presbycusis."1.28Sensorineural hearing loss: a reversible effect of valproic acid. ( Armon, C; Brown, E; Carwile, S; Miller, P; Shin, C, 1990)
"The paper describes the case of a depressive syndrome induced in a nine-year-old boy, with complex localised attacks and secondary generalisation, which completely receded on treatment with Convulsofin."1.28[A barbiturate derivative-induced depressive syndrome in a 9-year-old boy with complex focal seizures and secondary generalization--a case report]. ( Hässler, F, 1989)
" Fluctuations in the blood phenobarbital content from one administration to another is important for selecting its optimal dosage and the interval between intakes."1.27[Concentration of phenobarbital in biological fluids during the treatment of epilepsy patients]. ( Antadze, ZI; Okudzhava, VM; Vetrogon, FG, 1984)
"QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)."1.27Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986)
" It was found that: (1) a single dose of phenytoin suspension or capsules (5mg/kg/day) produced inadequate serum levels 16 and 24 hours after ingestion, and for this reason single dosage is not recommended; (2) twice-daily dosage of phenytoin suspension or capsules (5mg/kg/day) produced adequate serum levels in most children throughout the 24 hours, and this dosage is recommended; (3) 12 children continued to have seizures but when the dose was increased to 10mg/kg/day six of the 12 obtained control of seizures; (4) phenytoin reached equilibrium in the serum in five days provided the child had not previously been taking phenobarbitone; (5) of 13 children who had been taking phenobarbitone, 10 did not achieve equilibrium of phenytoin in serum for one to four weeks; (6) phenytoin suspension given twice-daily produced satisfactory serum levels provided the bottle was shaken well before dispensing; (7) apart from minor variations, phenytoin maintained its level in serum during the 14 to 30 months follow-up period, whether 5mg or 10mg/kg/day of phenytoin was given."1.26Phenytoin serum levels in children with epilepsy: a micro immuno-assay technique. ( Broughton, PM; Forsythe, WI; Prendergast, MP; Toothill, C, 1979)
"Homovanillic acid accumulation was decreased in this group."1.26Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology. ( Peters, JG, 1979)
"Although sneezing is a particularly common symptom, there are surprisingly few references to this subject in the medical literature."1.24PAROXYSMAL SNEEZING. ( KOFMAN, O, 1964)

Research

Studies (143)

TimeframeStudies, this research(%)All Research%
pre-1990111 (77.62)18.7374
1990's9 (6.29)18.2507
2000's9 (6.29)29.6817
2010's11 (7.69)24.3611
2020's3 (2.10)2.80

Authors

AuthorsStudies
Auer, T1
Schreppel, P2
Erker, T2
Schwarzer, C1
Łukawski, K1
Raszewski, G1
Czuczwar, SJ1
Barker-Haliski, M1
Knox, K1
Zierath, D1
Koneval, Z1
Metcalf, C1
Wilcox, KS1
White, HS1
Asgari, A1
Semnanian, S1
Atapour, N1
Shojaei, A1
Moradi, H1
Mirnajafi-Zadeh, J1
Bogdanović, RM1
Syvänen, S1
Michler, C2
Russmann, V2
Eriksson, J1
Windhorst, AD1
Lammertsma, AA1
de Lange, EC1
Voskuyl, RA1
Potschka, H4
Klein, S1
Bankstahl, M2
Löscher, W11
Brandt, C9
Töllner, K1
Twele, F1
Schidlitzki, A1
Haenisch, S1
von Rüden, EL1
Wahmkow, H1
Rettenbeck, ML1
Bruckmueller, H1
Waetzig, V1
Cascorbi, I1
Bethmann, K4
Fritschy, JM2
Nozadze, M1
Heuchert, N1
Rattka, M2
Schlichtiger, J2
Pekcec, A2
Bartmann, H2
Winter, P2
Fuest, C2
Soerensen, J2
la Fougere, C1
Xiong, G1
Just, T1
Böning, G1
Wängler, B1
Bartenstein, P1
Cumming, P1
Bankstahl, JP1
Klitgaard, H1
Matagne, A1
Grimee, R1
Vanneste-Goemaere, J1
Margineanu, DG1
JABBOUR, JT1
GIBBS, FA1
RICH, CL1
GIBBS, EL1
JIMENEZESPINOSA, L1
BAIRD, HW1
JONGMANS, JW1
PENIN, H1
KOFMAN, O1
PRESTON, DN1
ATACK, EA1
STRUNK, P1
JOHNSON, J1
Volk, HA2
Arabadzisz, D1
Gastens, AM1
Jiao, Y1
Nadler, JV1
Cabral Filho, G1
Mariani, MD1
Fonseca, LF1
Soares Neto, V1
Bolina, ND1
Schmidt, D4
Rowan, AJ1
Kato, H1
Biniaurishvili, RG1
Veĭn, AM1
Chalkov, VG1
Okudzhava, VM1
Antadze, ZI1
Vetrogon, FG1
Bruni, J1
Petrone, F1
Cavalcanti, S1
Turchiaro, GG1
Rolando, G1
Parraga, HC1
Simonds, JF1
Butterfield, PT1
Cahen, R1
Martin, A1
Francois, B1
Baltassat, P1
Louisot, P1
Kasamo, K1
Okuhata, Y1
Satoh, R1
Ikeda, M1
Takahashi, S1
Kamata, R1
Nogami, Y1
Kojima, T1
Dodman, NH2
Bronson, R1
Gliatto, J1
Husain, AM1
Carwile, ST1
Miller, PP1
Radtke, RA1
Tanuri, FD1
Thomaz, RB1
Tanuri, JA1
Tassinari, CA1
Roger, J1
Forsythe, WI1
Prendergast, MP1
Toothill, C1
Broughton, PM1
Aucamp, AK1
Browne, TR1
Hosokawa, K1
Kugoh, T1
Otsuki, S1
Nanda, RN1
Johnson, RH1
Keogh, HJ1
Lambie, DG1
Melville, ID1
Peters, JG1
Sironi, VA1
Franzini, A1
Ravagnati, L1
Marossero, F1
Barragry, JM1
Makin, HL1
Trafford, DJ1
Scott, DF1
Niebyl, JR1
Blake, DA1
Freeman, JM3
Luff, RD1
Wilder, BJ1
Ramsay, RE1
Boucharlat, PJ1
Ratel, M1
Maitre, A1
Ledru, J1
Shaywitz, BA1
Cohen, DJ1
Bowers, MB1
McNaughton, FL1
Rasmussen, T1
Singer, HS1
Kutt, H1
Solomon, G1
Wasterlain, C1
Peterson, H1
Louis, S1
Carruthers, R1
Dam, M3
Jensen, A1
Christiansen, J2
Richens, A2
Feldman, RG1
Pippenger, CE1
Mygind, KI1
Karbowski, K2
Meienberg, O1
Hassan, MN1
Laljee, HC1
Parsonage, MJ1
Thomas, JA1
Knotts, GR1
Mattson, RH3
Williamson, PD1
Hanahan, E1
Dugas, M1
Grenet, P1
Masson, M1
Mialet, JP1
Jaquet, G1
Kullander, S1
Van Buren, JM2
Ajmone-Marsan, C1
Mutsuga, N2
Sadowsky, D1
Marsan, CA1
Rodin, EA2
Cate JC, IV1
Tenser, R1
Houghton, GW1
Toseland, PA1
Davidson, S2
Raispis, T1
Dworsky, ME1
Miczek, KA1
Knowles, K1
Thalhammer, JG1
Shuster, L1
Clarke, BM1
Upton, A1
Griffin, H1
Hudoba, P1
Lai, CW1
Leppik, IE1
Jenkins, DC1
Sood, P1
McNamara, ME1
Fogel, BS1
Armon, C1
Brown, E1
Carwile, S1
Miller, P1
Shin, C1
Rascol, O1
Squalli, A1
Montastruc, JL1
Garat, A1
Houin, G1
Lachau, S1
Tor, J1
Blehaut, H1
Rascol, A1
Hara, H1
Fukuyama, Y1
Hässler, F1
Vezzani, A1
Wu, HQ1
Tullii, M1
Samanin, R1
Cornaggia, CM1
Canevini, MP1
Giuccioli, D1
Pruneri, C1
Canger, R1
Bova, VE1
Parish, RA1
Brownstein, D1
Frost, JD1
Kellaway, P1
Hrachovy, RA1
Glaze, DG1
Mizrahi, EM1
Rozza, L1
Marcolla, A1
Ferrari, G1
Brent, DA1
Vining, EP1
Falconer, MA2
Sibley, WA1
Kristianson, P1
Parsonage, M1
Hierons, R1
Saunders, M1
Sherwin, AL1
Wisen, AA1
Sokolowski, CD1
Billinghurst, JR1
German, GA1
Orley, JH1
Cereghino, JJ2
Brock, JT2
Van Meter, JC2
Penry, JK2
Smith, LD2
Fisher, P1
Ellenberg, J1
Gold, AP1
White, BG1
Rim, CS1
Rennick, PM1
Greene, CA1
Rao, VS1
Maragos, GD1
Mitchell, JR1
Taguchi, H1
Degen, R1
Helling, R1
Liu, MC1
Gibberd, FB1
Wilson, J1
Lieb, J1
Sclabassi, R1
Crandall, P1
Buchness, R1
Gavanski, N1
Malcolm, MT1
Tharp, BR1
Birket-Smith, E1
Lund, M1
Mikkelsen, B1
Vestermark, S1
Olsen, PZ1
Holm, P1
Travers, RD2
Reynolds, EH1
Gallagher, BB4
Baumel, IP2
Robinson, RJ1
Brett, EM1
Vajda, F1
Williams, FM1
Breckenridge, A1
Escueta, AV1
Boxley, J1
Stubbs, N1
Waddell, G1
Wilson, WA1
Tchicaloff, M1
Gudmundsson, G1
Matthes, A1
Hayashi, M1
Shimazono, Y1
Olesen, OV1
Roth, G1
Sie, PG1
Dumon-Radermecker, M1
Dowzenko, A1
Huber, Z2
Zieliński, JJ1
Suffczyńska-Kotowska, M1
Popielarska, A1
Mazurowa, M1
Spalona, M1
Borkowska, Z1
Mazurkowa, K1
Wojakowski, A1
Glaser, GH1
Toivakka, E1
Lehtinen, LO1
Hansotia, P1
Wadia, NH1
Zlotlow, M1
Villiger, A1

Reviews

5 reviews available for phenobarbital and Benign Psychomotor Epilepsy, Childhood

ArticleYear
Diagnosis and treatment of epilepsy.
    Hospital & community psychiatry, 1983, Volume: 34, Issue:6

    Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; E

1983
The pharmacological treatment of epilepsy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Oct-06, Volume: 56, Issue:15

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies,

1979
Drug therapy reviews: drug therapy of status epilepticus.
    American journal of hospital pharmacy, 1978, Volume: 35, Issue:8

    Topics: Anesthesia, General; Diazepam; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epil

1978
Diagnosis and treatment of epilepsy: overview and general principles.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination;

1974
Recent progress in epilepsy. Diagnostic procedures and treatment.
    California medicine, 1973, Volume: 119, Issue:1

    Topics: Anticonvulsants; Brain Neoplasms; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Temporal Lob

1973

Trials

14 trials available for phenobarbital and Benign Psychomotor Epilepsy, Childhood

ArticleYear
[Clinical and laboratory experience in the treatment of epilepsy with barbexaclone. Considerations on 29 cases].
    Arquivos de neuro-psiquiatria, 1980, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic;

1980
Single drug therapy for intractable epilepsy.
    Journal of neurology, 1983, Volume: 229, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Mi

1983
Treatment of epilepsy with clonazepam and its effect on other anticonvulsants.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Ambulatory Care; Benzodiazepinones; Brain; Child; Clinical Trials as Topic; Clona

1977
Oral and intramuscular phenytoin.
    Clinical pharmacology and therapeutics, 1976, Volume: 19, Issue:3

    Topics: Administration, Oral; Adult; Clinical Trials as Topic; Drug Administration Schedule; Epilepsy; Epile

1976
Carbamazepine in difficult to control epileptic out-patients.
    Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60

    Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic

1975
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1975, Volume: 60

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Thera

1975
The relation of anticonvulsant drug levels to complete seizure control.
    Journal of clinical pharmacology, 1976, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic;

1976
Eterobarb therapy in epilepsy.
    Neurology, 1976, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Epil

1976
A pilot study of stiripentol, a new anticonvulsant drug, in complex partial seizures uncontrolled by carbamazepine.
    Clinical neuropharmacology, 1989, Volume: 12, Issue:2

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dioxolanes; Dioxoles; Drug Sy

1989
Evaluation of albutoin as an antiepileptic drug.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutic

1974
Carbamazepine for epilepsy. A controlled prospective evaluation.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep

1974
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.
    Epilepsia, 1974, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials a

1974
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1973, Volume: 53

    Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinica

1973
The metabolic conversion of primidone (Mysoline) to phenobarbitone in patients under long-term treatment. An attempt to estimate the independent effect of primidone.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:3

    Topics: Adult; Behavior; Clinical Trials as Topic; Drug Synergism; Electroencephalography; Epilepsy; Epileps

1967

Other Studies

124 other studies available for phenobarbital and Benign Psychomotor Epilepsy, Childhood

ArticleYear
Functional characterization of novel bumetanide derivatives for epilepsy treatment.
    Neuropharmacology, 2020, 01-01, Volume: 162

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Bumetanide; Convulsants; Disease Models, Anima

2020
Effect of aliskiren on the anticonvulsant activity of antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice.
    Epilepsy research, 2020, Volume: 167

    Topics: Amides; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal;

2020
Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital.
    Epilepsia, 2021, Volume: 62, Issue:7

    Topics: Animals; Anticonvulsants; Body Weight; Convulsants; Cost of Illness; Disease Models, Animal; Drug Co

2021
Combined sub-threshold dosages of phenobarbital and low-frequency stimulation effectively reduce seizures in amygdala-kindled rats.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:8

    Topics: Amygdala; Animals; Anticonvulsants; Combined Modality Therapy; Deep Brain Stimulation; Disease Model

2014
(R)-[11C]PK11195 brain uptake as a biomarker of inflammation and antiepileptic drug resistance: evaluation in a rat epilepsy model.
    Neuropharmacology, 2014, Volume: 85

    Topics: Animals; Anticonvulsants; Brain; Carbon Radioisotopes; Carrier Proteins; Chronic Disease; Disease Mo

2014
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
    Neuropharmacology, 2015, Volume: 90

    Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrod

2015
The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice.
    Epilepsia, 2016, Volume: 57, Issue:5

    Topics: Animals; Anticonvulsants; Bumetanide; Convulsants; Disease Models, Animal; Dose-Response Relationshi

2016
miRNA-187-3p-Mediated Regulation of the KCNK10/TREK-2 Potassium Channel in a Rat Epilepsy Model.
    ACS chemical neuroscience, 2016, 11-16, Volume: 7, Issue:11

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Resistant Epilepsy; Dyrk Kinases; Electric St

2016
Antiepileptic drug resistant rats differ from drug responsive rats in GABA A receptor subunit expression in a model of temporal lobe epilepsy.
    Neurobiology of disease, 2008, Volume: 31, Issue:2

    Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Resistance; Electric Stimulati

2008
High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy.
    Epilepsia, 2010, Volume: 51, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dose-Respons

2010
Disease-modifying effects of phenobarbital and the NKCC1 inhibitor bumetanide in the pilocarpine model of temporal lobe epilepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jun-23, Volume: 30, Issue:25

    Topics: Amygdala; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Bumetanide; Cell Count;

2010
Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.
    British journal of pharmacology, 2010, Volume: 160, Issue:5

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Celecoxib;

2010
Imaging of P-glycoprotein-mediated pharmacoresistance in the hippocampus: proof-of-concept in a chronic rat model of temporal lobe epilepsy.
    Epilepsia, 2010, Volume: 51, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbon

2010
Inter-individual variation in the anticonvulsant effect of phenobarbital in the pilocarpine rat model of temporal lobe epilepsy.
    Experimental neurology, 2012, Volume: 234, Issue:1

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; E

2012
The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats.
    Epilepsy research, 2013, Volume: 103, Issue:2-3

    Topics: Animals; Anticonvulsants; Cognition Disorders; Disease Models, Animal; Epilepsy, Temporal Lobe; Fema

2013
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
    Seizure, 2003, Volume: 12, Issue:2

    Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe

2003
THE INFANT WITH EPILEPSY.
    Southwestern medicine, 1963, Volume: 44

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific

1963
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
    Neurology, 1963, Volume: 13

    Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, T

1963
[THERAPY OF EPILEPSY].
    Medicina espanola, 1964, Volume: 51

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Chlordiazepoxide; Epilepsy; Epilepsy, Temporal Lobe; H

1964
CONVULSIONS IN INFANCY AND CHILDHOOD.
    Pediatric clinics of North America, 1963, Volume: 10

    Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy,

1963
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
    Epilepsia, 1964, Volume: 5

    Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox

1964
[EFFECT AND INDICATION OF A NEW ANTIEPILEPTIC DRUG].
    Deutsche medizinische Wochenschrift (1946), 1964, Sep-04, Volume: 89

    Topics: Anticonvulsants; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tempor

1964
PAROXYSMAL SNEEZING.
    Canadian Medical Association journal, 1964, Jul-25, Volume: 91

    Topics: Anticonvulsants; Child; Child Psychiatry; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hydantoins; Met

1964
TEMPORAL LOBE EPILEPSY: A CLINICAL STUDY OF 47 CASES.
    Canadian Medical Association journal, 1964, Dec-12, Volume: 91

    Topics: Adolescent; Biomedical Research; Birth Injuries; Depression; Depressive Disorder; Diagnosis, Differe

1964
[CLINICAL CONTRIBUTION TO TEMPORAL LOBE EPILEPSY].
    Praxis der Kinderpsychologie und Kinderpsychiatrie, 1965, Volume: 14

    Topics: Adolescent; Child; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Humans;

1965
SEXUAL IMPOTENCE AND THE LIMBIC SYSTEM.
    The British journal of psychiatry : the journal of mental science, 1965, Volume: 111

    Topics: Astrocytoma; Brain Neoplasms; Diagnosis, Differential; Epilepsy; Epilepsy, Temporal Lobe; Erectile D

1965
Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus.
    Epilepsia, 2004, Volume: 45, Issue:12

    Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug R

2004
Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy.
    Neurobiology of disease, 2006, Volume: 21, Issue:3

    Topics: Animals; Anticonvulsants; Autoradiography; Disease Models, Animal; Drug Resistance; Electroencephalo

2006
The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy.
    Neurobiology of disease, 2006, Volume: 24, Issue:1

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins;

2006
Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy.
    Epilepsia, 2007, Volume: 48, Issue:4

    Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug R

2007
Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting.
    Experimental neurology, 2007, Volume: 205, Issue:2

    Topics: Algorithms; Animals; Anticonvulsants; Cell Count; Cell Shape; Dentate Gyrus; Epilepsy, Temporal Lobe

2007
Reduction of two-drug therapy in intractable epilepsy.
    Epilepsia, 1983, Volume: 24, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lob

1983
Antiepileptic drugs and psychiatric disorders: mechanism involved in manifestation of psychic symptoms of high blood level of antiepileptics.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3

    Topics: Adult; Anticonvulsants; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Male; Mental D

1983
[Clinical and electroencephalographic features of the action of the psychic stimulant sydnocarb in various forms of epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984, Volume: 84, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epileps

1984
[Concentration of phenobarbital in biological fluids during the treatment of epilepsy patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1984, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Chromatography, Gas; Epilepsy; Epilepsy, Temporal Lobe; Humans; Kinetics; Male; M

1984
Prognosis of chronic epilepsy with complex partial seizures.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:12

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electro

1984
Valproic acid and plasma levels of primidone and derived phenobarbital.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1981, Volume: 8, Issue:1

    Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Kineti

1981
[Polytherapy and monotherapy in the treatment of patients with epilepsy].
    Acta neurologica. Quaderni, 1981, Volume: 42

    Topics: Adult; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy,

1981
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:12

    Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps

1982
Iatrogenic behavioral and psychiatric symptoms in children with partial complex seizures.
    Journal of developmental and behavioral pediatrics : JDBP, 1982, Volume: 3, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Temporal Lobe; Female; Humans; Iatrogenic Disease; Mal

1982
Creatinine metabolism impairment by an anticonvulsant drug, phenacemide.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Adult; Anticonvulsants; Benzeneacetamides; Carbamazepine; Creatinine; Epilepsy, Temporal Lobe; Glome

1994
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
    European archives of psychiatry and clinical neuroscience, 1993, Volume: 243, Issue:2

    Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Human

1993
Tail chasing in a bull terrier.
    Journal of the American Veterinary Medical Association, 1993, Mar-01, Volume: 202, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dog Diseases; Dogs; Electroencephalography; Epileps

1993
Improved sexual function in three men taking lamotrigine for epilepsy.
    Southern medical journal, 2000, Volume: 93, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial;

2000
[Temporal lobe epilepsy with aura of pleasure. Case report].
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:1

    Topics: Anticonvulsants; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged; Orgas

2000
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
    Advances in neurology, 1975, Volume: 11

    Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Tempo

1975
Phenytoin serum levels in children with epilepsy: a micro immuno-assay technique.
    Developmental medicine and child neurology, 1979, Volume: 21, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy, Absence; Epilepsy,

1979
[Clinical study of serum level of dipropylacetic acid sodium (Depakene) by gaschromatography (author's transl)].
    No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Gas; Drug Therapy, Combination; Epilepsi

1977
Dopamine, noradrenaline and serotonin spinal fluid metabolites in temporal lobe epileptic patients with schizophrenic symptomatology.
    European neurology, 1979, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Child; Dopamine; Epilepsy, Temporal Lobe; Homovanillic Acid; Humans; Hydroxyindol

1979
Interictal acute psychoses in temporal lobe epilepsy during withdrawal of anticonvulsant therapy.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:8

    Topics: Adult; Carbamazepine; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy, Tempo

1979
Effect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:10

    Topics: Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female; Humans; Liver; Male; Phenobarbital;

1978
Carbamazepine levels in pregnancy and lactation.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:1

    Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Female; Fetal Blood; Fetus; Humans; Lactation; Milk,

1979
[Reflections on temporal epilepsy in the child].
    Annales medico-psychologiques, 1976, Volume: 134, Issue:4

    Topics: Adolescent; Anticonvulsants; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Social

1976
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
    Neurology, 1975, Volume: 25, Issue:1

    Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy

1975
Criteria for selection of patients for neurosurgical treatment.
    Advances in neurology, 1975, Volume: 8

    Topics: Adolescent; Age Factors; Child; Electroencephalography; Encephalitis; Epilepsies, Partial; Epilepsy;

1975
Seizures in adolescents.
    The Medical clinics of North America, 1975, Volume: 59, Issue:6

    Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differen

1975
Sensible prescribing. XI.--Juvenile and adult epilepsy.
    The Practitioner, 1975, Volume: 215, Issue:1289

    Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epile

1975
Phenytoin and phenobarbitone plasma clearance during pregnancy.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Adult; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Human

1976
[Epileptic seizures with psychomotor symptoms and generalized spike-wave-pattern].
    Der Nervenarzt, 1976, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Carbamazepine; Child; Diagnosis, Differential; Drug Therapy, Combination; Electro

1976
Sodium valproate in the treatment of resistant epilepsy.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies,

1976
Epilepsy and other seizure disorders in children: drug management.
    The Journal of school health, 1976, Volume: 46, Issue:8

    Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T

1976
[Childhood aphasia with epilepsy. Remission with antiepileptic treatment].
    Revue neurologique, 1976, Volume: 132, Issue:7

    Topics: Aphasia; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; Remission,

1976
Effect of 2 br-alpha-ergocryptin (CB 154) on serum prolactin and the clinical picture in a case of progressive gigantomastia in pregnancy.
    Annales chirurgiae et gynaecologiae, 1976, Volume: 65, Issue:4

    Topics: Adult; Breast Diseases; Bromocriptine; Carbamazepine; Diazepam; Epilepsy, Temporal Lobe; Ergolines;

1976
Surgery of temporal lobe epilepsy.
    Advances in neurology, 1975, Volume: 8

    Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroenc

1975
Temporal-lobe seizures with additional foci treated by resection.
    Journal of neurosurgery, 1975, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Brain Neoplasms; Child; Electrodes, Implanted; Electroencephalography; Epilepsy,

1975
Psychosocial management of patients with complex partial seizures.
    Advances in neurology, 1975, Volume: 11

    Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; E

1975
Acute primidone overdosage with massive crystalluria.
    Clinical toxicology, 1975, Volume: 8, Issue:4

    Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital;

1975
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
    European journal of clinical pharmacology, 1975, Oct-10, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal

1975
Benign Familial Neonatal Seizures.
    Alabama medicine : journal of the Medical Association of the State of Alabama, 1992, Volume: 62, Issue:5

    Topics: Adult; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 20; Diagnosis, Differe

1992
Phenobarbital-responsive episodic dyscontrol (rage) in dogs.
    Journal of the American Veterinary Medical Association, 1992, Nov-15, Volume: 201, Issue:10

    Topics: Aggression; Animals; Behavior, Animal; Dog Diseases; Dogs; Electroencephalography; Epilepsy, Tempora

1992
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
    Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:1

    Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male

1991
Epilepsy, myasthenia gravis, and effect of plasmapheresis on antiepileptic drug concentrations.
    Archives of neurology, 1990, Volume: 47, Issue:1

    Topics: Adult; Anticonvulsants; Combined Modality Therapy; Drug Therapy, Combination; Epilepsy, Temporal Lob

1990
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
    The Journal of neuropsychiatry and clinical neurosciences, 1990,Spring, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencepha

1990
Sensorineural hearing loss: a reversible effect of valproic acid.
    Neurology, 1990, Volume: 40, Issue:12

    Topics: Aged; Audiometry; Epilepsy, Temporal Lobe; Hearing Loss, Sensorineural; Humans; Male; Phenobarbital;

1990
Sustained attention during the interictal period of mentally normal children with epilepsy or febrile convulsions, and the influence of anticonvulsants and seizures on attention.
    The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:3

    Topics: Anticonvulsants; Attention; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; Ep

1989
[A barbiturate derivative-induced depressive syndrome in a 9-year-old boy with complex focal seizures and secondary generalization--a case report].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1989, Volume: 41, Issue:12

    Topics: Anticonvulsants; Child; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Epilepsie

1989
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models,

1986
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
    Italian journal of neurological sciences, 1986, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, T

1986
[Treatment of epileptic patients with Jacksonian seizures].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:6

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Drug Therapy, Combination; Epilepsies, Partial; Epilep

1986
Emergency department management of children with acute isoniazid poisoning.
    Pediatric emergency care, 1986, Volume: 2, Issue:2

    Topics: Adolescent; Child; Diazepam; Emergencies; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epilepsy, To

1986
Changes in epileptic spike configuration associated with attainment of seizure control.
    Annals of neurology, 1986, Volume: 20, Issue:6

    Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epi

1986
Endocrine function changes in young males during long-term antiepileptic therapy with phenobarbitone and carbamazepine.
    Italian journal of neurological sciences, 1987, Volume: 8, Issue:4

    Topics: Adult; Carbamazepine; Drug Therapy, Combination; Endocrine Glands; Epilepsies, Partial; Epilepsy, Te

1987
Overrepresentation of epileptics in a consecutive series of suicide attempters seen at a children's hospital, 1978-1983.
    Journal of the American Academy of Child Psychiatry, 1986, Volume: 25, Issue:2

    Topics: Adolescent; Child; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Male; Phenobarbital; Risk; Sui

1986
Where, why, and what type of therapy.
    Pediatric annals, 1985, Volume: 14, Issue:11

    Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Hum

1985
Mesial temporal (Ammon's horn) sclerosis as a common cause of epilepsy. Aetiology, treatment, and prevention.
    Lancet (London, England), 1974, Sep-28, Volume: 2, Issue:7883

    Topics: Administration, Oral; Adolescent; Animals; Brain Diseases; Child; Child, Preschool; Diazepam; Epilep

1974
A comparison between the personality changes in certain forms of psychomotor and grand-mal epilepsy.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 125, Issue:0

    Topics: Adult; Depression; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans;

1974
Epilepsy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec

1974
Impotence in patients with temporal-lobe lesions.
    Lancet (London, England), 1966, Oct-08, Volume: 2, Issue:7467

    Topics: Adult; Craniocerebral Trauma; Electroencephalography; Epilepsy, Temporal Lobe; Erectile Dysfunction;

1966
Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.
    Archives of neurology, 1973, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Biopsy; Cerebral Cortex; Child; Electroencephalography; Epilepsies

1973
The pattern of epilepsy in Uganda.
    Tropical and geographical medicine, 1973, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epile

1973
Psychomotor epilepsy in childhood.
    Pediatrics, 1974, Volume: 53, Issue:4

    Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; E

1974
On the relationship migraine--epilepsy.
    The Nebraska state medical journal, 1971, Volume: 56, Issue:4

    Topics: Anticonvulsants; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Migraine Disorders; Phenob

1971
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants.
    Acta medicinae Okayama, 1971, Volume: 25, Issue:5

    Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Diet; Epilepsy, Temporal Lobe; Folic Acid; Folic Acid De

1971
[The treatment of epiletic seizures in childhood].
    Munchener medizinische Wochenschrift (1950), 1968, May-24, Volume: 110, Issue:21

    Topics: Adrenocorticotropic Hormone; Ambulatory Care; Anticonvulsants; Barbiturates; Child; Child, Preschool

1968
Clinical experience with sulthiame (Ospolot).
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:487

    Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans;

1966
Epilepsy.
    British medical journal, 1969, Nov-01, Volume: 4, Issue:5678

    Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T

1969
Drug treatment of epilepsy in childhood.
    British medical journal, 1969, Nov-22, Volume: 4, Issue:5681

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epil

1969
Comparison of the action of diazepam and phenobarbital using EEG-derived power spectra obtained from temporal lobe epileptics.
    Neuropharmacology, 1974, Volume: 13, Issue:8

    Topics: Adult; Amygdala; Cerebral Cortex; Diazepam; Electrodes, Implanted; Electroencephalography; Epilepsy,

1974
[Phenomenology and therapy of temporal epilepsy in various age groups].
    Neuropsihijatrija, 1974, Volume: 22, Issue:1-4

    Topics: Adolescent; Adult; Carbamazepine; Child; Epilepsy, Temporal Lobe; Humans; Phenobarbital

1974
Temporal lobe epilepsy due to drug withdrawal.
    The British journal of addiction to alcohol and other drugs, 1972, Volume: 67, Issue:4

    Topics: Barbiturates; Diazepam; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged

1972
Variation in response to anticonvulsants in a group of epileptic patients.
    Archives of neurology, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, To

1972
Phenylethylmalonamide (PEMA). An important metabolite of primidone.
    Archives of neurology, 1972, Volume: 27, Issue:1

    Topics: Adult; Amides; Animals; Blood Proteins; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, Toni

1972
Metabolic disposition of primidone and its metabolites in epileptic subjects after single and repeated administration.
    Neurology, 1972, Volume: 22, Issue:11

    Topics: Amides; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Primidone

1972
Febrile convulsions.
    Guy's Hospital reports, 1973, Volume: 122, Issue:1-2

    Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Epilepsy, Temporal Lobe; Female; Fever of Unknown

1973
Treatment of febrile convulsions.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:5

    Topics: Anticonvulsants; Aspirin; Child; Child, Preschool; Diazepam; Epilepsy, Temporal Lobe; Fever; Humans;

1974
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe;

1974
Prolonged twilight state and automatisms: a case report.
    Neurology, 1974, Volume: 24, Issue:4

    Topics: Adult; Automatism; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans;

1974
[New methods of seizure treatment in epilepsy].
    Munchener medizinische Wochenschrift (1950), 1965, Nov-05, Volume: 107, Issue:45

    Topics: Acetazolamide; Anticonvulsants; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tempo

1965
Epilepsy in Iceland. A clinical and epidemiological investigation.
    Acta neurologica Scandinavica, 1966, Volume: 43

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Automobile Driving; Child; Child, Preschool; Epilepsy, Abs

1966
[Treatment of epilepsy in children].
    Deutsche medizinische Wochenschrift (1946), 1967, Jun-09, Volume: 92, Issue:23

    Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epil

1967
[Experience in the clinical use of K4-1152].
    No to shinkei = Brain and nerve, 1967, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Automatism; Child; Electroencephalography; Epilepsy; Epilepsy, Temporal Lob

1967
[On the combination treatment of epileptic attacks].
    Wiener medizinische Wochenschrift (1946), 1968, Feb-10, Volume: 118, Issue:6

    Topics: Anticonvulsants; Drug Synergism; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Ton

1968
Extractum belladonnae as an adjuvant to luminal in the therapy of epilepsy with a possible explanation in neurophysiological and neurochemical terms.
    Proceedings of the Australian Association of Neurologists, 1968, Volume: 5, Issue:1

    Topics: Acetylcholine; Adolescent; Adult; Animals; Anticonvulsants; Anura; Atropine; Cats; Cerebral Cortex;

1968
[Results obtained with Depakine in epilepsy resistant to other therapies. Preliminary note].
    Acta neurologica et psychiatrica Belgica, 1969, Volume: 69, Issue:11

    Topics: Acetates; Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epile

1969
[Problems of treatment of epilepsy].
    Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3

    Topics: Anemia, Macrocytic; Anticonvulsants; Bromides; Diazepam; Drug Synergism; Epilepsy; Epilepsy, Tempora

1971
[Evaluation of treatment of absence seizures in children].
    Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Child; Child, Preschool; Drug Synergism; Electroen

1971
[Effect of hydantoin together with small doses of phenobarbital in various forms of epileptic seizures].
    Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Brain; Child; Drug Synergism; Electroencephalography; Epilepsi

1971
[Results of treatment of epilepsy in children up to 14 years of age].
    Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3

    Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroenc

1971
Variation in response to anticonvulsants in a group of epileptic patients.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone

1971
Musicogenic epilepsy. A case report.
    Acta neurologica Scandinavica. Supplementum, 1965, Volume: 13 Pt 2

    Topics: Adult; Chlordiazepoxide; Electroencephalography; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Hearin

1965
[Experimental vestibular vertigo in healthy and in epileptic patients].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1968, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Calorimetry; Ear, Inner; Electroencephalography; Epilepsy; Epilepsy, Temporal Lob

1968
Temporal lobe epilepsy with "absences".
    Diseases of the nervous system, 1971, Volume: 32, Issue:5

    Topics: Adult; Cognition Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Methohe

1971
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
    The Psychiatric quarterly, 1968, Volume: 42, Issue:4

    Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography;

1968
[On the problem of the effect of brain lesions on the vestibular system].
    Practica oto-rhino-laryngologica, 1966, Volume: 28, Issue:1

    Topics: Brain Neoplasms; Cerebral Cortex; Electroencephalography; Epilepsy, Temporal Lobe; Eye Movements; Fi

1966