Page last updated: 2024-11-02

phenobarbital and Atrophy

phenobarbital has been researched along with Atrophy in 6 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Neonatal stroke presents with seizures that are usually treated with phenobarbital."7.77Different effects of high- and low-dose phenobarbital on post-stroke seizure suppression and recovery in immature CD1 mice. ( Comi, AM; Johnston, MV; Kadam, SD; Markowitz, GJ; Smith, DR, 2011)
"Neonatal stroke presents with seizures that are usually treated with phenobarbital."3.77Different effects of high- and low-dose phenobarbital on post-stroke seizure suppression and recovery in immature CD1 mice. ( Comi, AM; Johnston, MV; Kadam, SD; Markowitz, GJ; Smith, DR, 2011)
"Macro square wave jerks and pendular nystagmus were mildly suppressed after the intramuscular injection of 100 mg of phenobarbital, the oral intake of sodium valproate of 600 mg/day or baclofen of 60 mg/day."1.28[Multiple system atrophy with macro square wave jerks and pendular nystagmus]. ( Fukusako, T; Morimatsu, M; Nogaki, H; Yamamoto, K, 1992)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Markowitz, GJ1
Kadam, SD1
Smith, DR1
Johnston, MV1
Comi, AM1
OKUDA, O1
SHINOHARA, S1
Lindberg, RL1
Porcher, C1
Grandchamp, B1
Ledermann, B1
Bürki, K1
Brandner, S1
Aguzzi, A1
Meyer, UA1
Botez, MI1
Peyronnard, JM1
Bérubé, L1
Labrecque, R1
Yamamoto, K1
Fukusako, T1
Nogaki, H1
Morimatsu, M1
Jensen, ON1
Olesen, OV1

Other Studies

6 other studies available for phenobarbital and Atrophy

ArticleYear
Different effects of high- and low-dose phenobarbital on post-stroke seizure suppression and recovery in immature CD1 mice.
    Epilepsy research, 2011, Volume: 94, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Atrophy; Body Weight; Cognition Disorders;

2011
[OBSERVATION ON TWO CASES OF EPILEPSIA CURSIVA].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1964, Volume: 66

    Topics: Adolescent; Atrophy; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Dichlorphenamide; Electroencep

1964
Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria.
    Nature genetics, 1996, Volume: 12, Issue:2

    Topics: Aminolevulinic Acid; Animals; Atrophy; Axons; Base Sequence; Chimera; Disease Models, Animal; Female

1996
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
    Applied neurophysiology, 1979, Volume: 42, Issue:3

    Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intesti

1979
[Multiple system atrophy with macro square wave jerks and pendular nystagmus].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:11

    Topics: Atrophy; Baclofen; Brain Diseases; Diazepam; Electrooculography; Eye Movements; Female; Humans; Midd

1992
Folic acid concentrations in cerebrospinal fluid in relation to anticonvulsant drugs and cerebral atrophy.
    Acta psychiatrica Scandinavica, 1971, Volume: 47, Issue:2

    Topics: Adult; Anticonvulsants; Atrophy; Brain Diseases; Epilepsy; Female; Folic Acid; Humans; Male; Mental

1971