phenobarbital has been researched along with Atrial Fibrillation in 5 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Additionally, in this case the interaction was managed with concentration-guided dosing of apixaban, suggesting this approach may represent a feasible strategy for managing patients requiring treatment with direct-acting oral anticoagulants and enzyme-inducing antiepileptic drugs." | 1.48 | Managing Direct Oral Anticoagulants in Patients With Antiepileptic Medication. ( Dagan, G; Hochberg-Klein, S; Kalish, Y; Muszkat, M; Perlman, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dagan, G | 1 |
| Perlman, A | 1 |
| Hochberg-Klein, S | 1 |
| Kalish, Y | 1 |
| Muszkat, M | 1 |
| Yang, YH | 1 |
| Zheng, QS | 1 |
| Li, J | 1 |
| Shang, FJ | 1 |
| Liu, T | 1 |
| Wang, HT | 1 |
| Liu, XT | 1 |
| Liu, L | 1 |
| Nölker, G | 1 |
| Sinha, AM | 1 |
| FOERSTER, K | 1 |
| KROETZ, C | 1 |
| DeSilva, RA | 1 |
| Graboys, TB | 1 |
| Podrid, PJ | 1 |
| Lown, B | 1 |
1 review available for phenobarbital and Atrial Fibrillation
| Article | Year |
|---|---|
Cardioversion and defibrillation.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Catheterization; Diazepa | 1980 |
4 other studies available for phenobarbital and Atrial Fibrillation
| Article | Year |
|---|---|
Managing Direct Oral Anticoagulants in Patients With Antiepileptic Medication.
Topics: Administration, Oral; Aged, 80 and over; Anticoagulants; Anticonvulsants; Atrial Fibrillation; Drug | 2018 |
Age-related changes in the atrial muscarinic type 2 receptor and their effects on atrial fibrillation vulnerability in rabbits.
Topics: Aging; Animals; Atrial Fibrillation; Atrial Function, Left; Atrial Function, Right; Blotting, Wester | 2009 |
Gastroesophageal reflux after RF ablation of AF.
Topics: Atrial Fibrillation; Catheter Ablation; Drug Combinations; Esophageal Fistula; Gastroesophageal Refl | 2010 |
[ANTI-ARRHYTHMIC SUBSTANCES IN THE TREATMENT OF THE HEART].
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Drug Ther | 1965 |