Page last updated: 2024-11-02

phenobarbital and Atresia, Biliary

phenobarbital has been researched along with Atresia, Biliary in 8 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis."7.79Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013)
" Group 1 (n = 48), group 2 (n = 29), and group 3 (n = 18) received phenobarbital at the dosage of 5 mg/kg/day for at least 5 days, less than 5 mg/kg/day or less than 5 days, and no premedication, respectively."5.32The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome. ( Charearnrad, P; Chongsrisawat, V; Poovorawan, Y; Tepmongkol, S, 2003)
"The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis."3.79Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013)
"Phenobarbital is a long-acting barbiturate metabolized in the liver by the cytochrome p450 3a4 system."1.33Treatment of acute tacrolimus whole-blood elevation with phenobarbital in the pediatric liver transplant recipient. ( Bristow, LJ; Chang, IF; Goss, JA; Karpen, SJ; Quirós-Tejeira, RE, 2005)
" Group 1 (n = 48), group 2 (n = 29), and group 3 (n = 18) received phenobarbital at the dosage of 5 mg/kg/day for at least 5 days, less than 5 mg/kg/day or less than 5 days, and no premedication, respectively."1.32The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome. ( Charearnrad, P; Chongsrisawat, V; Poovorawan, Y; Tepmongkol, S, 2003)
"Phenobarbital was administered to 22 patients before imaging."1.29Utility of Tc-99m mebrofenin scintigraphy in the assessment of infantile jaundice. ( Ben-Haim, S; Brown, BP; Johnson, J; Kao, SC; Seabold, JE; Tran, D, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwatra, N1
Shalaby-Rana, E1
Narayanan, S1
Mohan, P1
Ghelani, S1
Majd, M1
Charearnrad, P1
Chongsrisawat, V1
Tepmongkol, S1
Poovorawan, Y1
Quirós-Tejeira, RE1
Chang, IF1
Bristow, LJ1
Karpen, SJ1
Goss, JA1
Sevilla, A1
Howman-Giles, R1
Saleh, H1
Trpezanovski, J1
Concannon, R1
Williams, K1
Chung, D1
Uren, R1
Ben-Haim, S1
Seabold, JE1
Kao, SC1
Johnson, J1
Tran, D1
Brown, BP1
Lin, WY1
Lin, CC1
Changlai, SP1
Shen, YY1
Wang, SJ1
Golladay, ES1
Slezak, JW1
Seibert, JJ1
Rivera-Echegoyen, M1
Ramírez-Mayans, JA1
Casaubón-Garcín, P1
Núñez-Malaver, CE1
Avila-Ramírez, E1
Sosa-Martínez, C1

Other Studies

8 other studies available for phenobarbital and Atresia, Biliary

ArticleYear
Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center.
    Pediatric radiology, 2013, Volume: 43, Issue:10

    Topics: Biliary Atresia; Causality; Cholestasis; District of Columbia; Female; Humans; Image Enhancement; In

2013
The effect of phenobarbital on the accuracy of technetium-99m diisopropyl iminodiacetic acid hepatobiliary scintigraphy in differentiating biliary atresia from neonatal hepatitis syndrome.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86 Suppl 2

    Topics: Biliary Atresia; Excitatory Amino Acid Antagonists; Female; Hepatitis; Humans; Infant; Infant, Newbo

2003
Treatment of acute tacrolimus whole-blood elevation with phenobarbital in the pediatric liver transplant recipient.
    Pediatric transplantation, 2005, Volume: 9, Issue:6

    Topics: Biliary Atresia; Half-Life; Humans; Immunosuppressive Agents; Infant; Liver Transplantation; Male; P

2005
Hepatobiliary scintigraphy with SPECT in infancy.
    Clinical nuclear medicine, 2007, Volume: 32, Issue:1

    Topics: Biliary Atresia; Female; Humans; Infant; Infant, Newborn; Liver Diseases; Male; Phenobarbital; Retro

2007
Utility of Tc-99m mebrofenin scintigraphy in the assessment of infantile jaundice.
    Clinical nuclear medicine, 1995, Volume: 20, Issue:2

    Topics: Aniline Compounds; Biliary Atresia; Cholestasis, Intrahepatic; Female; Glycine; Hepatitis; Humans; I

1995
Comparison technetium of Tc-99m disofenin cholescintigraphy with ultrasonography in the differentiation of biliary atresia from other forms of neonatal jaundice.
    Pediatric surgery international, 1997, Volume: 12, Issue:1

    Topics: Biliary Atresia; Cholestyramine Resin; Diagnosis, Differential; Female; Humans; Imino Acids; Infant;

1997
Intractable cholangitis due to conduit obstruction.
    The Journal of the Arkansas Medical Society, 1990, Volume: 87, Issue:3

    Topics: Anti-Bacterial Agents; Biliary Atresia; Child; Cholangitis; Clinical Protocols; Humans; Methylpredni

1990
[Neonatal cholestatic syndrome: use of phenobarbital in the gammagram of the bile ducts].
    Boletin medico del Hospital Infantil de Mexico, 1988, Volume: 45, Issue:10

    Topics: Bile Ducts; Biliary Atresia; Bilirubin; Diagnosis, Differential; Female; Humans; Imino Acids; Infant

1988